Result of FASTA (omim) for pF1KE1026
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1026, 979 aa
  1>>>pF1KE1026 979 - 979 aa - 979 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 17.1524+/-0.000566; mu= -31.7690+/- 0.036
 mean_var=832.9317+/-169.272, 0's: 0 Z-trim(124.1): 38  B-trim: 0 in 0/59
 Lambda= 0.044440
 statistics sampled from 44978 (45028) to 44978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.528), width:  16
 Scan time: 16.820

The best scores are:                                      opt bits E(85289)
NP_002909 (OMIM: 600006) MHC class II regulatory f ( 979) 6473 431.1 1.4e-119
XP_011526471 (OMIM: 600006) PREDICTED: MHC class I ( 980) 4695 317.1 2.9e-85
XP_011526472 (OMIM: 600006) PREDICTED: MHC class I ( 980) 4695 317.1 2.9e-85
XP_011526467 (OMIM: 600006) PREDICTED: MHC class I (1089) 4695 317.1 3.1e-85
XP_011526468 (OMIM: 600006) PREDICTED: MHC class I (1089) 4695 317.1 3.1e-85
XP_011526469 (OMIM: 600006) PREDICTED: MHC class I (1089) 4695 317.1 3.1e-85
XP_011526470 (OMIM: 600006) PREDICTED: MHC class I ( 991) 3749 256.5 5.2e-67
XP_016870490 (OMIM: 601337) PREDICTED: transcripti ( 724) 2484 175.2 1.1e-42
NP_001269045 (OMIM: 601337) transcription factor R ( 749) 2439 172.4 8.1e-42
NP_602304 (OMIM: 601337) transcription factor RFX3 ( 749) 2439 172.4 8.1e-42
XP_011516302 (OMIM: 601337) PREDICTED: transcripti ( 745) 2426 171.5 1.4e-41
XP_006716903 (OMIM: 601337) PREDICTED: transcripti ( 780) 2383 168.8   1e-40
XP_011516301 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
XP_006716907 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
XP_006716908 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
XP_016870489 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
XP_006716906 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
XP_011516300 (OMIM: 601337) PREDICTED: transcripti ( 770) 2381 168.7 1.1e-40
NP_002910 (OMIM: 601337) transcription factor RFX3 ( 707) 2378 168.4 1.2e-40
XP_011516303 (OMIM: 601337) PREDICTED: transcripti ( 687) 2342 166.1 5.6e-40
XP_016882597 (OMIM: 142765) PREDICTED: DNA-binding ( 653) 2297 163.2   4e-39
NP_602309 (OMIM: 142765) DNA-binding protein RFX2  ( 698) 2297 163.2 4.2e-39
XP_011526473 (OMIM: 142765) PREDICTED: DNA-binding ( 723) 2263 161.1   2e-38
NP_000626 (OMIM: 142765) DNA-binding protein RFX2  ( 723) 2263 161.1   2e-38
XP_011526474 (OMIM: 142765) PREDICTED: DNA-binding ( 687) 2247 160.0 3.8e-38
XP_016882596 (OMIM: 142765) PREDICTED: DNA-binding ( 678) 2238 159.4 5.7e-38
XP_006716910 (OMIM: 601337) PREDICTED: transcripti ( 492) 1742 127.5 1.7e-28
XP_016870491 (OMIM: 601337) PREDICTED: transcripti ( 501) 1736 127.2 2.2e-28
NP_001269046 (OMIM: 601337) transcription factor R ( 413) 1037 82.3 5.9e-15
NP_115880 (OMIM: 603958) transcription factor RFX4 ( 641)  568 52.4 9.3e-06


>>NP_002909 (OMIM: 600006) MHC class II regulatory facto  (979 aa)
 initn: 6473 init1: 6473 opt: 6473  Z-score: 2267.9  bits: 431.1 E(85289): 1.4e-119
Smith-Waterman score: 6473; 99.9% identity (100.0% similar) in 979 aa overlap (1-979:1-979)

               10        20        30        40        50        60
pF1KE1 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 PGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 VPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVPVPHVYSSQVQYVEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVPVPHVYSSQVQYVEG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 GDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPMYV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPMYV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 SGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYM
       :::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 LGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 GKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE1 KPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE1 GPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE1 RLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLES
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE1 WLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE1 VDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE1 GFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAKGE
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE1 TPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLEPP
              910       920       930       940       950       960

              970         
pF1KE1 AKLARTDARGLFVQALPSS
       :::::::::::::::::::
NP_002 AKLARTDARGLFVQALPSS
              970         

>>XP_011526471 (OMIM: 600006) PREDICTED: MHC class II re  (980 aa)
 initn: 4600 init1: 4600 opt: 4695  Z-score: 1651.8  bits: 317.1 E(85289): 2.9e-85
Smith-Waterman score: 5457; 88.7% identity (88.8% similar) in 980 aa overlap (110-979:1-980)

      80        90       100       110       120       130         
pF1KE1 AVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEASPGSTASQTGVPTQVVQQVQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MRASETVSEASPGSTASQTGVPTQVVQQVQ
                                             10        20        30

     140       150       160       170       180       190         
pF1KE1 GTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSAAPGSKGGQVSLTVHGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSAAPGSKGGQVSLTVHGT
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KE1 QQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQERSVVQATPQAPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQERSVVQATPQAPKP
              100       110       120       130       140       150

     260       270                                                 
pF1KE1 GPVQPLTVQGLQPVHVAQE-----------------------------------------
       :::::::::::::::::::                                         
XP_011 GPVQPLTVQGLQPVHVAQESSGSQFPARKAEQRDPRPTPPPEPPPRPPACSGEAPQLGSP
              160       170       180       190       200       210

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 EPPPPHYEPGAEQWVELVGVLPPHLLLPQQKVVFEPLSRLPARASPDQRVRIQRIPQVLV
              220       230       240       250       260       270

               280       290       300       310       320         
pF1KE1 ---------VQQLQQVPVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTAST
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGTAATALKVQQLQQVPVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTAST
              280       290       300       310       320       330

     330       340       350       360       370       380         
pF1KE1 SYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSASTGAGASNSSGGGGSGGGG
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 SYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGG
              340       350       360       370       380       390

     390       400       410       420       430       440         
pF1KE1 GGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSHTTRASPATVQWLLDNYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSHTTRASPATVQWLLDNYETA
              400       410       420       430       440       450

     450       460       470       480       490       500         
pF1KE1 EGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGL
              460       470       480       490       500       510

     510       520       530       540       550       560         
pF1KE1 RIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQPSTGLSDISAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQPSTGLSDISAQ
              520       530       540       550       560       570

     570       580       590       600       610       620         
pF1KE1 VQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFT
              580       590       600       610       620       630

     630       640       650       660       670       680         
pF1KE1 LVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQ
              640       650       660       670       680       690

     690       700       710       720       730       740         
pF1KE1 GLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLR
              700       710       720       730       740       750

     750       760       770       780       790       800         
pF1KE1 RYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFK
              760       770       780       790       800       810

     810       820       830       840       850       860         
pF1KE1 VTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSA
              820       830       840       850       860       870

     870       880       890       900       910       920         
pF1KE1 ASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEE
              880       890       900       910       920       930

     930       940       950       960       970         
pF1KE1 EEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARGLFVQALPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARGLFVQALPSS
              940       950       960       970       980

>>XP_011526472 (OMIM: 600006) PREDICTED: MHC class II re  (980 aa)
 initn: 4600 init1: 4600 opt: 4695  Z-score: 1651.8  bits: 317.1 E(85289): 2.9e-85
Smith-Waterman score: 5457; 88.7% identity (88.8% similar) in 980 aa overlap (110-979:1-980)

      80        90       100       110       120       130         
pF1KE1 AVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEASPGSTASQTGVPTQVVQQVQ
                                     ::::::::::::::::::::::::::::::
XP_011                               MRASETVSEASPGSTASQTGVPTQVVQQVQ
                                             10        20        30

     140       150       160       170       180       190         
pF1KE1 GTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSAAPGSKGGQVSLTVHGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVVQSAAPGSKGGQVSLTVHGT
               40        50        60        70        80        90

     200       210       220       230       240       250         
pF1KE1 QQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQERSVVQATPQAPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQSVPVTQERSVVQATPQAPKP
              100       110       120       130       140       150

     260       270                                                 
pF1KE1 GPVQPLTVQGLQPVHVAQE-----------------------------------------
       :::::::::::::::::::                                         
XP_011 GPVQPLTVQGLQPVHVAQESSGSQFPARKAEQRDPRPTPPPEPPPRPPACSGEAPQLGSP
              160       170       180       190       200       210

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 EPPPPHYEPGAEQWVELVGVLPPHLLLPQQKVVFEPLSRLPARASPDQRVRIQRIPQVLV
              220       230       240       250       260       270

               280       290       300       310       320         
pF1KE1 ---------VQQLQQVPVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTAST
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGTAATALKVQQLQQVPVPHVYSSQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTAST
              280       290       300       310       320       330

     330       340       350       360       370       380         
pF1KE1 SYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSASTGAGASNSSGGGGSGGGG
       ::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 SYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGG
              340       350       360       370       380       390

     390       400       410       420       430       440         
pF1KE1 GGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSHTTRASPATVQWLLDNYETA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSHTTRASPATVQWLLDNYETA
              400       410       420       430       440       450

     450       460       470       480       490       500         
pF1KE1 EGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGL
              460       470       480       490       500       510

     510       520       530       540       550       560         
pF1KE1 RIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQPSTGLSDISAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQPSTGLSDISAQ
              520       530       540       550       560       570

     570       580       590       600       610       620         
pF1KE1 VQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFT
              580       590       600       610       620       630

     630       640       650       660       670       680         
pF1KE1 LVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQ
              640       650       660       670       680       690

     690       700       710       720       730       740         
pF1KE1 GLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLR
              700       710       720       730       740       750

     750       760       770       780       790       800         
pF1KE1 RYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFK
              760       770       780       790       800       810

     810       820       830       840       850       860         
pF1KE1 VTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSA
              820       830       840       850       860       870

     870       880       890       900       910       920         
pF1KE1 ASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEE
              880       890       900       910       920       930

     930       940       950       960       970         
pF1KE1 EEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARGLFVQALPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARGLFVQALPSS
              940       950       960       970       980

>>XP_011526467 (OMIM: 600006) PREDICTED: MHC class II re  (1089 aa)
 initn: 4600 init1: 4600 opt: 4695  Z-score: 1651.2  bits: 317.1 E(85289): 3.1e-85
Smith-Waterman score: 5668; 89.0% identity (89.1% similar) in 1011 aa overlap (79-979:79-1089)

       50        60        70        80        90       100        
pF1KE1 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
                                     ::::::::::::::::::::::::::::::
XP_011 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
       50        60        70        80        90       100        

      110       120       130       140       150       160        
pF1KE1 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
      110       120       130       140       150       160        

      170       180       190       200       210       220        
pF1KE1 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
      170       180       190       200       210       220        

      230       240       250       260       270                  
pF1KE1 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQE----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQESSGSQFPARK
      230       240       250       260       270       280        

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 AEQRDPRPTPPPEPPPRPPACSGEAPQLGSPEPPPPHYEPGAEQWVELVGVLPPHLLLPQ
      290       300       310       320       330       340        

                                              280       290        
pF1KE1 ----------------------------------------VQQLQQVPVPHVYSSQVQYV
                                               ::::::::::::::::::::
XP_011 QKVVFEPLSRLPARASPDQRVRIQRIPQVLVFGTAATALKVQQLQQVPVPHVYSSQVQYV
      350       360       370       380       390       400        

      300       310       320       330       340       350        
pF1KE1 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
      410       420       430       440       450       460        

      360       370       380       390       400       410        
pF1KE1 YVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
      470       480       490       500       510       520        

      420       430       440       450       460       470        
pF1KE1 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
      530       540       550       560       570       580        

      480       490       500       510       520       530        
pF1KE1 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
      590       600       610       620       630       640        

      540       550       560       570       580       590        
pF1KE1 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
      650       660       670       680       690       700        

      600       610       620       630       640       650        
pF1KE1 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
      710       720       730       740       750       760        

      660       670       680       690       700       710        
pF1KE1 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
      770       780       790       800       810       820        

      720       730       740       750       760       770        
pF1KE1 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
      830       840       850       860       870       880        

      780       790       800       810       820       830        
pF1KE1 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
      890       900       910       920       930       940        

      840       850       860       870       880       890        
pF1KE1 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
      950       960       970       980       990      1000        

      900       910       920       930       940       950        
pF1KE1 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
     1010      1020      1030      1040      1050      1060        

      960       970         
pF1KE1 PPAKLARTDARGLFVQALPSS
       :::::::::::::::::::::
XP_011 PPAKLARTDARGLFVQALPSS
     1070      1080         

>--
 initn: 575 init1: 575 opt: 575  Z-score: 223.7  bits: 53.0 E(85289): 1e-05
Smith-Waterman score: 575; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)

               10        20        30        40        50        60
pF1KE1 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
       ::::::::::::::::::                                          
XP_011 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
               70        80        90       100       110       120

>>XP_011526468 (OMIM: 600006) PREDICTED: MHC class II re  (1089 aa)
 initn: 4600 init1: 4600 opt: 4695  Z-score: 1651.2  bits: 317.1 E(85289): 3.1e-85
Smith-Waterman score: 5668; 89.0% identity (89.1% similar) in 1011 aa overlap (79-979:79-1089)

       50        60        70        80        90       100        
pF1KE1 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
                                     ::::::::::::::::::::::::::::::
XP_011 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
       50        60        70        80        90       100        

      110       120       130       140       150       160        
pF1KE1 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
      110       120       130       140       150       160        

      170       180       190       200       210       220        
pF1KE1 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
      170       180       190       200       210       220        

      230       240       250       260       270                  
pF1KE1 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQE----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQESSGSQFPARK
      230       240       250       260       270       280        

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 AEQRDPRPTPPPEPPPRPPACSGEAPQLGSPEPPPPHYEPGAEQWVELVGVLPPHLLLPQ
      290       300       310       320       330       340        

                                              280       290        
pF1KE1 ----------------------------------------VQQLQQVPVPHVYSSQVQYV
                                               ::::::::::::::::::::
XP_011 QKVVFEPLSRLPARASPDQRVRIQRIPQVLVFGTAATALKVQQLQQVPVPHVYSSQVQYV
      350       360       370       380       390       400        

      300       310       320       330       340       350        
pF1KE1 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
      410       420       430       440       450       460        

      360       370       380       390       400       410        
pF1KE1 YVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
      470       480       490       500       510       520        

      420       430       440       450       460       470        
pF1KE1 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
      530       540       550       560       570       580        

      480       490       500       510       520       530        
pF1KE1 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
      590       600       610       620       630       640        

      540       550       560       570       580       590        
pF1KE1 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
      650       660       670       680       690       700        

      600       610       620       630       640       650        
pF1KE1 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
      710       720       730       740       750       760        

      660       670       680       690       700       710        
pF1KE1 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
      770       780       790       800       810       820        

      720       730       740       750       760       770        
pF1KE1 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
      830       840       850       860       870       880        

      780       790       800       810       820       830        
pF1KE1 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
      890       900       910       920       930       940        

      840       850       860       870       880       890        
pF1KE1 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
      950       960       970       980       990      1000        

      900       910       920       930       940       950        
pF1KE1 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
     1010      1020      1030      1040      1050      1060        

      960       970         
pF1KE1 PPAKLARTDARGLFVQALPSS
       :::::::::::::::::::::
XP_011 PPAKLARTDARGLFVQALPSS
     1070      1080         

>--
 initn: 575 init1: 575 opt: 575  Z-score: 223.7  bits: 53.0 E(85289): 1e-05
Smith-Waterman score: 575; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)

               10        20        30        40        50        60
pF1KE1 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
       ::::::::::::::::::                                          
XP_011 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
               70        80        90       100       110       120

>>XP_011526469 (OMIM: 600006) PREDICTED: MHC class II re  (1089 aa)
 initn: 4600 init1: 4600 opt: 4695  Z-score: 1651.2  bits: 317.1 E(85289): 3.1e-85
Smith-Waterman score: 5668; 89.0% identity (89.1% similar) in 1011 aa overlap (79-979:79-1089)

       50        60        70        80        90       100        
pF1KE1 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
                                     ::::::::::::::::::::::::::::::
XP_011 TPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEG
       50        60        70        80        90       100        

      110       120       130       140       150       160        
pF1KE1 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMRASETVSEASPGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQV
      110       120       130       140       150       160        

      170       180       190       200       210       220        
pF1KE1 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQQALPTQRLVVQSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTV
      170       180       190       200       210       220        

      230       240       250       260       270                  
pF1KE1 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQE----------
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_011 PQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQESSGSQFPARK
      230       240       250       260       270       280        

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 AEQRDPRPTPPPEPPPRPPACSGEAPQLGSPEPPPPHYEPGAEQWVELVGVLPPHLLLPQ
      290       300       310       320       330       340        

                                              280       290        
pF1KE1 ----------------------------------------VQQLQQVPVPHVYSSQVQYV
                                               ::::::::::::::::::::
XP_011 QKVVFEPLSRLPARASPDQRVRIQRIPQVLVFGTAATALKVQQLQQVPVPHVYSSQVQYV
      350       360       370       380       390       400        

      300       310       320       330       340       350        
pF1KE1 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPM
      410       420       430       440       450       460        

      360       370       380       390       400       410        
pF1KE1 YVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGG
      470       480       490       500       510       520        

      420       430       440       450       460       470        
pF1KE1 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAA
      530       540       550       560       570       580        

      480       490       500       510       520       530        
pF1KE1 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQ
      590       600       610       620       630       640        

      540       550       560       570       580       590        
pF1KE1 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLKPIQKMEGMTNGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPE
      650       660       670       680       690       700        

      600       610       620       630       640       650        
pF1KE1 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEA
      710       720       730       740       750       760        

      660       670       680       690       700       710        
pF1KE1 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSL
      770       780       790       800       810       820        

      720       730       740       750       760       770        
pF1KE1 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDL
      830       840       850       860       870       880        

      780       790       800       810       820       830        
pF1KE1 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQG
      890       900       910       920       930       940        

      840       850       860       870       880       890        
pF1KE1 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAK
      950       960       970       980       990      1000        

      900       910       920       930       940       950        
pF1KE1 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLE
     1010      1020      1030      1040      1050      1060        

      960       970         
pF1KE1 PPAKLARTDARGLFVQALPSS
       :::::::::::::::::::::
XP_011 PPAKLARTDARGLFVQALPSS
     1070      1080         

>--
 initn: 575 init1: 575 opt: 575  Z-score: 223.7  bits: 53.0 E(85289): 1e-05
Smith-Waterman score: 575; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)

               10        20        30        40        50        60
pF1KE1 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
       ::::::::::::::::::                                          
XP_011 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
               70        80        90       100       110       120

>>XP_011526470 (OMIM: 600006) PREDICTED: MHC class II re  (991 aa)
 initn: 5447 init1: 3584 opt: 3749  Z-score: 1324.0  bits: 256.5 E(85289): 5.2e-67
Smith-Waterman score: 5406; 80.9% identity (80.9% similar) in 1089 aa overlap (1-979:1-991)

               10        20        30        40        50        60
pF1KE1 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MATQAYTELQAAPPPSQPPQAPPQAQPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQPQAQPPGGQKQYVTELPAVPAPSQPTGAPTPSPAPQQYIVVTVSEGAMRASETVSEAS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 PGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGSTASQTGVPTQVVQQVQGTQQRLLVQTSVQAKPGHVSPLQLTNIQVPQQALPTQRLVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 QSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSAAPGSKGGQVSLTVHGTQQVHSPPEQSPVQANSSSSKTAGAPTGTVPQQLQVHGVQQS
              190       200       210       220       230       240

              250       260       270                              
pF1KE1 VPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQE----------------------
       ::::::::::::::::::::::::::::::::::::::                      
XP_011 VPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQESSGSQFPARKAEQRDPRPTPPP
              250       260       270       280       290       300

                                                                   
pF1KE1 ------------------------------------------------------------
                                                                   
XP_011 EPPPRPPACSGEAPQLGSPEPPPPHYEPGAEQWVELVGVLPPHLLLPQQKVVFEPLSRLP
              310       320       330       340       350       360

                                  280       290       300       310
pF1KE1 ----------------------------VQQLQQVPVPHVYSSQVQYVEGGDASYTASAI
                                   ::::::::::::::::::::::::::::::::
XP_011 ARASPDQRVRIQRIPQVLVFGTAATALKVQQLQQVPVPHVYSSQVQYVEGGDASYTASAI
              370       380       390       400       410       420

              320       330       340       350       360       370
pF1KE1 RSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPMYVSGSQVVASSA
       :::::::::::::::::::::::::::::::                             
XP_011 RSSTYSYPETPLYTQTASTSYYEAAGTATQV-----------------------------
              430       440       450                              

              380       390       400       410       420       430
pF1KE1 STGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQGGYMLGSASQSYSH
                                                                   
XP_011 ------------------------------------------------------------
                                                                   

              440       450       460       470       480       490
pF1KE1 TTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMG
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ---------QWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMG
                      460       470       480       490       500  

              500       510       520       530       540       550
pF1KE1 LRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMT
            510       520       530       540       550       560  

              560       570       580       590       600       610
pF1KE1 NGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGVAVGQQPSTGLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGVGPGDIKAFQV
            570       580       590       600       610       620  

              620       630       640       650       660       670
pF1KE1 LYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPKAILVLL
            630       640       650       660       670       680  

              680       690       700       710       720       730
pF1KE1 SKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIP
            690       700       710       720       730       740  

              740       750       760       770       780       790
pF1KE1 EEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQA
            750       760       770       780       790       800  

              800       810       820       830       840       850
pF1KE1 SWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFPKAAKLFL
            810       820       830       840       850       860  

              860       870       880       890       900       910
pF1KE1 LKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFA
            870       880       890       900       910       920  

              920       930       940       950       960       970
pF1KE1 NLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPALGPETLEPPAKLARTDARG
            930       940       950       960       970       980  

                
pF1KE1 LFVQALPSS
       :::::::::
XP_011 LFVQALPSS
            990 

>>XP_016870490 (OMIM: 601337) PREDICTED: transcription f  (724 aa)
 initn: 2407 init1: 1360 opt: 2484  Z-score: 887.5  bits: 175.2 E(85289): 1.1e-42
Smith-Waterman score: 2671; 62.0% identity (82.2% similar) in 676 aa overlap (268-937:29-659)

       240       250       260       270       280        290      
pF1KE1 QQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVP-VPHVYSSQVQ
                                     : .: : : :.:::.: :  : ::: .:::
XP_016   MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQ
                 10        20        30        40        50        

        300       310       320       330       340       350      
pF1KE1 YVEGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSM
       ::::.:. :: .:::..:: : :: .:.:... .:... :...::.: ..:......:..
XP_016 YVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGI
       60        70        80        90       100       110        

        360       370       380       390       400       410      
pF1KE1 PMYVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQ
        : :.:.:...::.                                        :::.: 
XP_016 QMGVTGGQLISSSG----------------------------------------GTYLI-
      120       130                                                

        420       430       440       450       460       470      
pF1KE1 GGYMLGSASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVN
        :  . ....: .:::::::::.::::::::::::::::::::: ::: ::::.::.:::
XP_016 -GNSMENSGHSVTHTTRASPATLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVN
        140       150       160       170       180       190      

        480       490       500       510       520       530      
pF1KE1 AASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQ
       ::::::::::.:::::::::::::::::::::.:.: .::: ::.::.:.:::: ::..:
XP_016 AASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQ
        200       210       220       230       240       250      

        540       550        560        570       580       590    
pF1KE1 KQRLKPIQKMEGMTNG-VAVGQQPSTGLSD-ISAQVQQYQQFLDASRSLPDFTELDLQGK
       ::: ::.::..:...: .. ::: .:.. . . :: :..::::::::.::.: :..... 
XP_016 KQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISS-
        260       270       280       290       300       310      

          600       610       620       630       640       650    
pF1KE1 VLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAV
        ::.:.   :::..: :::::::::.::.:::::.:.: ::.:::::. : :...  .. 
XP_016 -LPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTITE
          320       330       340       350       360       370    

             660       670       680       690       700       710 
pF1KE1 HD---EAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAI
        .   : :.::::: :. : : : .:.:  .::. .::.:::::::::::::::::::::
XP_016 SSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAI
          380       390       400       410       420       430    

             720       730       740       750       760       770 
pF1KE1 RNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQI
       ::::::::.::..:: :::..:...::::..::::::::::::::::::::::::::.::
XP_016 RNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQI
          440       450       460       470       480       490    

             780       790       800       810       820       830 
pF1KE1 NQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQ
       :::::::::::::::::::::::.:.: .::::: :::.:::::..:::::::::.:. :
XP_016 NQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQ
          500       510       520       530       540       550    

             840       850       860       870       880       890 
pF1KE1 VLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIE
       .::::.:  .:::::. ::::::::::::::::::::::::::::::::::::::.::.:
XP_016 ALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVE
          560       570       580       590       600       610    

             900       910       920       930       940       950 
pF1KE1 HRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESPA
       :::::: :::::::::::..: ....: . ::::  : : : ..::              
XP_016 HRVAQATGETPIAVMGEFGDL-NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKTE
          620       630        640       650       660       670   

             960       970                                
pF1KE1 LGPETLEPPAKLARTDARGLFVQALPSS                       
                                                          
XP_016 LSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
           680       690       700       710       720    

>>NP_001269045 (OMIM: 601337) transcription factor RFX3   (749 aa)
 initn: 2571 init1: 1360 opt: 2439  Z-score: 871.7  bits: 172.4 E(85289): 8.1e-42
Smith-Waterman score: 2636; 61.2% identity (82.3% similar) in 677 aa overlap (268-937:29-684)

       240       250       260       270       280        290      
pF1KE1 QQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVP-VPHVYSSQVQ
                                     : .: : : :.:::.: :  : ::: .:::
NP_001   MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQ
                 10        20        30        40        50        

        300       310       320       330       340       350      
pF1KE1 YVEGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSM
       ::::.:. :: .:::..:: : :: .:.:... .:... :...::.: ..:......:..
NP_001 YVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGI
       60        70        80        90       100       110        

        360       370       380       390       400       410      
pF1KE1 PMYVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQ
        : :.:.:...::                  ::    :..  .:: .    . :.  .:.
NP_001 QMGVTGGQLISSS------------------GGTYLIGNSMENSGHSVTHTTRASPATIE
      120       130                         140       150       160

        420        430       440       450       460       470     
pF1KE1 GGYMLGSASQSYS-HTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPV
        .    . :.. : : .    . .::::::::::::::::::::: ::: ::::.::.::
NP_001 MAIETLQKSDGLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPV
              170       180       190       200       210       220

         480       490       500       510       520       530     
pF1KE1 NAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFS
       :::::::::::.:::::::::::::::::::::.:.: .::: ::.::.:.:::: ::..
NP_001 NAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQ
              230       240       250       260       270       280

         540       550        560        570       580       590   
pF1KE1 QKQRLKPIQKMEGMTNG-VAVGQQPSTGLSD-ISAQVQQYQQFLDASRSLPDFTELDLQG
       :::: ::.::..:...: .. ::: .:.. . . :: :..::::::::.::.: :.....
NP_001 QKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISS
              290       300       310       320       330       340

           600       610       620       630       640       650   
pF1KE1 KVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLA
         ::.:.   :::..: :::::::::.::.:::::.:.: ::.:::::. : :...  ..
NP_001 --LPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTIT
                350       360       370       380       390        

              660       670       680       690       700       710
pF1KE1 VHD---EAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQA
         .   : :.::::: :. : : : .:.:  .::. .::.::::::::::::::::::::
NP_001 ESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQA
      400       410       420       430       440       450        

              720       730       740       750       760       770
pF1KE1 IRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQ
       :::::::::.::..:: :::..:...::::..::::::::::::::::::::::::::.:
NP_001 IRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQ
      460       470       480       490       500       510        

              780       790       800       810       820       830
pF1KE1 INQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVS
       ::::::::::::::::::::::::.:.: .::::: :::.:::::..:::::::::.:. 
NP_001 INQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMM
      520       530       540       550       560       570        

              840       850       860       870       880       890
pF1KE1 QVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLI
       :.::::.:  .:::::. ::::::::::::::::::::::::::::::::::::::.::.
NP_001 QALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLV
      580       590       600       610       620       630        

              900       910       920       930       940       950
pF1KE1 EHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESP
       ::::::: :::::::::::..: ....: . ::::  : : : ..::             
NP_001 EHRVAQATGETPIAVMGEFGDL-NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKT
      640       650       660        670       680       690       

              960       970                                
pF1KE1 ALGPETLEPPAKLARTDARGLFVQALPSS                       
                                                           
NP_001 ELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
       700       710       720       730       740         

>>NP_602304 (OMIM: 601337) transcription factor RFX3 iso  (749 aa)
 initn: 2571 init1: 1360 opt: 2439  Z-score: 871.7  bits: 172.4 E(85289): 8.1e-42
Smith-Waterman score: 2636; 61.2% identity (82.3% similar) in 677 aa overlap (268-937:29-684)

       240       250       260       270       280        290      
pF1KE1 QQSVPVTQERSVVQATPQAPKPGPVQPLTVQGLQPVHVAQEVQQLQQVP-VPHVYSSQVQ
                                     : .: : : :.:::.: :  : ::: .:::
NP_602   MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQ
                 10        20        30        40        50        

        300       310       320       330       340       350      
pF1KE1 YVEGGDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSM
       ::::.:. :: .:::..:: : :: .:.:... .:... :...::.: ..:......:..
NP_602 YVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGI
       60        70        80        90       100       110        

        360       370       380       390       400       410      
pF1KE1 PMYVSGSQVVASSASTGAGASNSSGGGGSGGGGGGGGGGGGGGSGSTGGGGSGAGTYVIQ
        : :.:.:...::                  ::    :..  .:: .    . :.  .:.
NP_602 QMGVTGGQLISSS------------------GGTYLIGNSMENSGHSVTHTTRASPATIE
      120       130                         140       150       160

        420        430       440       450       460       470     
pF1KE1 GGYMLGSASQSYS-HTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPV
        .    . :.. : : .    . .::::::::::::::::::::: ::: ::::.::.::
NP_602 MAIETLQKSDGLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPV
              170       180       190       200       210       220

         480       490       500       510       520       530     
pF1KE1 NAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFS
       :::::::::::.:::::::::::::::::::::.:.: .::: ::.::.:.:::: ::..
NP_602 NAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQ
              230       240       250       260       270       280

         540       550        560        570       580       590   
pF1KE1 QKQRLKPIQKMEGMTNG-VAVGQQPSTGLSD-ISAQVQQYQQFLDASRSLPDFTELDLQG
       :::: ::.::..:...: .. ::: .:.. . . :: :..::::::::.::.: :.....
NP_602 QKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISS
              290       300       310       320       330       340

           600       610       620       630       640       650   
pF1KE1 KVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLA
         ::.:.   :::..: :::::::::.::.:::::.:.: ::.:::::. : :...  ..
NP_602 --LPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPTDGTTIT
                350       360       370       380       390        

              660       670       680       690       700       710
pF1KE1 VHD---EAEKRLPKAILVLLSKFEPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQA
         .   : :.::::: :. : : : .:.:  .::. .::.::::::::::::::::::::
NP_602 ESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQA
      400       410       420       430       440       450        

              720       730       740       750       760       770
pF1KE1 IRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQ
       :::::::::.::..:: :::..:...::::..::::::::::::::::::::::::::.:
NP_602 IRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQ
      460       470       480       490       500       510        

              780       790       800       810       820       830
pF1KE1 INQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVS
       ::::::::::::::::::::::::.:.: .::::: :::.:::::..:::::::::.:. 
NP_602 INQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMM
      520       530       540       550       560       570        

              840       850       860       870       880       890
pF1KE1 QVLKPYQGSAGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLI
       :.::::.:  .:::::. ::::::::::::::::::::::::::::::::::::::.::.
NP_602 QALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLV
      580       590       600       610       620       630        

              900       910       920       930       940       950
pF1KE1 EHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGGESP
       ::::::: :::::::::::..: ....: . ::::  : : : ..::             
NP_602 EHRVAQATGETPIAVMGEFGDL-NAVSPGNLDKDEGSEVESEMDEELDDSSEPQAKREKT
      640       650       660        670       680       690       

              960       970                                
pF1KE1 ALGPETLEPPAKLARTDARGLFVQALPSS                       
                                                           
NP_602 ELSQAFPVGCMQPVLETGVQPSLLNPIHSEHIVTSTQTIRQCSATGNTYTAV
       700       710       720       730       740         




979 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:28:00 2016 done: Sat Nov  5 07:28:03 2016
 Total Scan time: 16.820 Total Display time:  0.330

Function used was FASTA [36.3.4 Apr, 2011]
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