Result of FASTA (omim) for
pF1KE1035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1035, 428 aa
1>>>pF1KE1035 428 - 428 aa - 428 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3307+/-0.000407; mu= 17.7082+/- 0.025
mean_var=69.7180+/-13.921, 0's: 0 Z-trim(111.2): 165 B-trim: 42 in 3/51
Lambda= 0.153604
statistics sampled from 19547 (19721) to 19547 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.231), width: 16
Scan time: 8.600
The best scores are: opt bits E(85289)
NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 2817 633.6 2.9e-181
NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 2817 633.6 2.9e-181
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 888 206.1 1.3e-52
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 884 205.2 2.5e-52
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 874 203.0 1.1e-51
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 838 195.1 3.3e-49
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 838 195.1 3.3e-49
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 838 195.1 3.3e-49
NP_009135 (OMIM: 606168) probable ATP-dependent RN ( 824) 782 182.8 2.8e-45
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 732 171.6 3.7e-42
NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479) 724 169.8 1.3e-41
XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484) 724 169.8 1.3e-41
XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539) 724 169.8 1.5e-41
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 688 162.0 5.1e-39
NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370) 676 159.1 1.7e-38
XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 676 159.1 1.7e-38
XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 676 159.1 1.7e-38
NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370) 676 159.1 1.7e-38
NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370) 676 159.1 1.7e-38
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 670 157.8 4.5e-38
NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 660 155.5 1.9e-37
NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448) 644 152.1 2.7e-36
NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453) 644 152.1 2.8e-36
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 644 152.1 2.9e-36
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 644 152.1 2.9e-36
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 644 152.1 2.9e-36
XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508) 644 152.1 3e-36
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 640 151.3 6.6e-36
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 640 151.3 6.6e-36
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 640 151.3 6.6e-36
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 640 151.3 6.6e-36
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 600 142.3 2e-33
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 588 139.7 1.5e-32
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 588 139.7 1.7e-32
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 588 139.7 1.7e-32
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 588 139.7 1.9e-32
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 588 139.8 2e-32
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 578 137.6 1.1e-31
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 578 137.6 1.3e-31
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 578 137.6 1.3e-31
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 578 137.6 1.3e-31
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 578 137.6 1.3e-31
XP_011540947 (OMIM: 600326) PREDICTED: probable AT ( 434) 572 136.1 1.7e-31
NP_001244104 (OMIM: 605812) ATP-dependent RNA heli ( 328) 569 135.4 2.1e-31
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 570 135.8 4.1e-31
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 570 135.8 4.1e-31
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 566 134.9 6.5e-31
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 566 134.9 6.5e-31
XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 557 132.9 2.4e-30
NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 546 130.4 1.2e-29
>>NP_542165 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 2817 init1: 2817 opt: 2817 Z-score: 3375.3 bits: 633.6 E(85289): 2.9e-181
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428)
10 20 30 40 50 60
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
370 380 390 400 410 420
pF1KE1 SSYIEQTR
::::::::
NP_542 SSYIEQTR
>>NP_004631 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 2817 init1: 2817 opt: 2817 Z-score: 3375.3 bits: 633.6 E(85289): 2.9e-181
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428)
10 20 30 40 50 60
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
370 380 390 400 410 420
pF1KE1 SSYIEQTR
::::::::
NP_004 SSYIEQTR
>>NP_001958 (OMIM: 601102) eukaryotic initiation factor (407 aa)
initn: 798 init1: 411 opt: 888 Z-score: 1065.4 bits: 206.1 E(85289): 1.3e-52
Smith-Waterman score: 888; 38.9% identity (73.0% similar) in 370 aa overlap (47-415:35-400)
20 30 40 50 60 70
pF1KE1 EVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECI
: :. :: :::.: :::.:: .:.. :
NP_001 SADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE1 PQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERF
: :.::. ::.:: ::::.:... ::::: ....::. ::::: ::.: .
NP_001 IPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILAL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE1 SKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILD
. :: .. . .:: ..... . :. . ::::::::::.. . . :. : :: :.::
NP_001 GDYM-GATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLD
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE1 ECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETK
: :.:: . .. .. :::. ::...:::. .. : .:::.::..:.: : .
NP_001 EADEMLSR-GFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE-E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE1 LTLHGLQQYYVKLKDNE-KNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAI
:::.:..:.:.... .: : : :: ..: ..:.:::... .. :.. . ..: .
NP_001 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE1 AIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRV
:.: : :.:: ...:.. . :.:..:.:..::.:...:....:::.: . ..:.::.
NP_001 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
310 320 330 340 350 360
380 390 400 410 420
pF1KE1 ARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
.:.:::: ::.::.::..: : .:: :.. ..... :.:
NP_001 GRGGRFGRKGVAINFVTEE-DKRILRDIETFYNTTVEEMPMNVADLI
370 380 390 400
>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation (411 aa)
initn: 766 init1: 408 opt: 884 Z-score: 1060.5 bits: 205.2 E(85289): 2.5e-52
Smith-Waterman score: 884; 38.1% identity (73.0% similar) in 370 aa overlap (47-415:40-404)
20 30 40 50 60 70
pF1KE1 EVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECI
: . :. .:::.: :::.:: .:.. :
NP_055 SGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE1 PQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERF
: : : ::. :..:: ::::.: ...:: :. . ....:.. ::::: ::.: .
NP_055 KQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLAL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE1 SKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILD
. :: ::. . .:: .. .: . : . :.:.:::::.. . : .:: . :: ..::
NP_055 GDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLD
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE1 ECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETK
: :.::.. ..... ...:. : ::...:::: .:: . ::: ::..:.: . .
NP_055 EADEMLNK-GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRD-E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE1 LTLHGLQQYYVKLKDNE-KNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAI
:::.:..:..: .. .: : : :: :.: ..:.::: .. .. :.. . : :: .
NP_055 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE1 AIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRV
..: :::.:: : ...:.. :.:..:....::.:. .:.. .:::.:.. . :.::.
NP_055 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI
310 320 330 340 350 360
380 390 400 410 420
pF1KE1 ARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
.:.::.: ::.::.::... : .:: :... . ..:.:.:
NP_055 GRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQIDEMPMNVADLI
370 380 390 400 410
>>NP_001407 (OMIM: 602641) eukaryotic initiation factor (406 aa)
initn: 780 init1: 405 opt: 874 Z-score: 1048.6 bits: 203.0 E(85289): 1.1e-51
Smith-Waterman score: 874; 37.1% identity (72.3% similar) in 394 aa overlap (23-415:13-399)
10 20 30 40 50 60
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
: :: : : . ..... : .: : :. :. :::.:
NP_001 MSASQDSRSRDNGPDGME-P-EGVIESNWNEIVDS-FDDMNLSESLLRGI
10 20 30 40
70 80 90 100 110 120
pF1KE1 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
:::.:: .:.. : : :.::. ::.:: ::::.:... :::.: ...::.
NP_001 YAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE1 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
::::: ::.: .. :: ... . .:: ... . . :. . :::.::::::.. .
NP_001 PTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDML
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE1 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
. :. :.:: :.::: :.:: . .. .. .::. . ::...:::. ... : .
NP_001 NRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTK
170 180 190 200 210 220
250 260 270 280 290
pF1KE1 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVLEFNQVVIFVKSVQR
:::.::..:.: : .:::.:..:.:.... .: : : :: ..: ..:.:::... ..
NP_001 KFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 CIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIA
:.. . ..: . :.: : :.:: ...:.. . :.:..:.:..::.:...:...
NP_001 VDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE1 FNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEID
.:::.: . ..:.::..:.:::: ::.::..:..: : . : :.. ....: :.:
NP_001 INYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIETFYNTSIEEMPLNVA
350 360 370 380 390 400
420
pF1KE1 ISSYIEQTR
NP_001 DLI
>>NP_001244120 (OMIM: 600326) probable ATP-dependent RNA (483 aa)
initn: 723 init1: 349 opt: 838 Z-score: 1004.4 bits: 195.1 E(85289): 3.3e-49
Smith-Waterman score: 838; 34.7% identity (67.8% similar) in 429 aa overlap (4-426:49-472)
10 20 30
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAK-
: ..: . .. . : :: . :
NP_001 GQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKL
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 --KD--VKGSYV-SIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC
:: .: : : : ... :.:. :: ::: .: . :.:.:: .:.: :: :. : :.:
NP_001 PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 QAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAV
.::.: ::...... :..:. .....:. :::::.:.:. . ::.: ..:: .
NP_001 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDM
:: ... : : . :.:..:::::: : .. .. :.. ..::: ::.: : :.
NP_001 TTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 RRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYV
. ...:. :...:....:::. .. . .: :.:: . .: :::.:. :::.
NP_001 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 KLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL
. . .: . : :.. :..:: .:: .: :: ::. . . .. . :: : ::.:
NP_001 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLA
...:.. : :: :.:: ::.::. ::...:.:.:. ..:::::..:.:::: :::
NP_001 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA
380 390 400 410 420 430
390 400 410 420
pF1KE1 ITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
:.... .: :....... ..:. .:..:: : :. .
NP_001 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
440 450 460 470 480
>>NP_004388 (OMIM: 600326) probable ATP-dependent RNA he (483 aa)
initn: 723 init1: 349 opt: 838 Z-score: 1004.4 bits: 195.1 E(85289): 3.3e-49
Smith-Waterman score: 838; 34.7% identity (67.8% similar) in 429 aa overlap (4-426:49-472)
10 20 30
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAK-
: ..: . .. . : :: . :
NP_004 GQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKL
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 --KD--VKGSYV-SIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC
:: .: : : : ... :.:. :: ::: .: . :.:.:: .:.: :: :. : :.:
NP_004 PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 QAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAV
.::.: ::...... :..:. .....:. :::::.:.:. . ::.: ..:: .
NP_004 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDM
:: ... : : . :.:..:::::: : .. .. :.. ..::: ::.: : :.
NP_004 TTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 RRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYV
. ...:. :...:....:::. .. . .: :.:: . .: :::.:. :::.
NP_004 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 KLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL
. . .: . : :.. :..:: .:: .: :: ::. . . .. . :: : ::.:
NP_004 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLA
...:.. : :: :.:: ::.::. ::...:.:.:. ..:::::..:.:::: :::
NP_004 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA
380 390 400 410 420 430
390 400 410 420
pF1KE1 ITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
:.... .: :....... ..:. .:..:: : :. .
NP_004 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
440 450 460 470 480
>>XP_005271474 (OMIM: 600326) PREDICTED: probable ATP-de (483 aa)
initn: 723 init1: 349 opt: 838 Z-score: 1004.4 bits: 195.1 E(85289): 3.3e-49
Smith-Waterman score: 838; 34.7% identity (67.8% similar) in 429 aa overlap (4-426:49-472)
10 20 30
pF1KE1 MAENDVDNELLDYEDDEVETAAGGDGAEAPAK-
: ..: . .. . : :: . :
XP_005 GQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKL
20 30 40 50 60 70
40 50 60 70 80
pF1KE1 --KD--VKGSYV-SIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLC
:: .: : : : ... :.:. :: ::: .: . :.:.:: .:.: :: :. : :.:
XP_005 PPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILA
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE1 QAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAV
.::.: ::...... :..:. .....:. :::::.:.:. . ::.: ..:: .
XP_005 RAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMA
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDM
:: ... : : . :.:..:::::: : .. .. :.. ..::: ::.: : :.
XP_005 TTGGTNLRDDIMRLD-DTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DF
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 RRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYV
. ...:. :...:....:::. .. . .: :.:: . .: :::.:. :::.
XP_005 VQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYA
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE1 KLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERL
. . .: . : :.. :..:: .:: .: :: ::. . . .. . :: : ::.:
XP_005 YVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRN
320 330 340 350 360 370
330 340 350 360 370 380
pF1KE1 SRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLA
...:.. : :: :.:: ::.::. ::...:.:.:. ..:::::..:.:::: :::
XP_005 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA
380 390 400 410 420 430
390 400 410 420
pF1KE1 ITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
:.... .: :....... ..:. .:..:: : :. .
XP_005 INLIT-YDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
440 450 460 470 480
>>NP_009135 (OMIM: 606168) probable ATP-dependent RNA he (824 aa)
initn: 793 init1: 366 opt: 782 Z-score: 933.9 bits: 182.8 E(85289): 2.8e-45
Smith-Waterman score: 782; 35.2% identity (67.1% similar) in 398 aa overlap (37-426:54-447)
10 20 30 40 50 60
pF1KE1 DNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFE
:. . . . :...::. .:... :::
NP_009 AVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFE
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 HPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELA
.:: :: . :: . :.:.. ::::: ::: :: .:..: . ....:.. :::.:
NP_009 RPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIA
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 FQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLN
:: . .. : ... ::.:: ...:. ::: : ::.::.:::: : . ::
NP_009 VQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK-C-HIAVGSPGRIKQLIELDYLN
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE1 LKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDP
:. ::::: ::.::. ....... :. : ::.. ::: . . . :.:.::
NP_009 PGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDP
210 220 230 240 250 260
250 260 270 280 290
pF1KE1 MEIFVDDETKLTLHGLQQYYVKLKD--------NEKNRKLFDLLDVLEFNQVVIFVKSVQ
. ... . .: ::.::: ... .::...: .:.. . :::...: . .
NP_009 TFVRLNS-SDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQELFSRIPFNQALVFSNLHS
270 280 290 300 310 320
300 310 320 330 340 350
pF1KE1 RCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI
: ::..: ..::: : .: :..::. . ..: :. :.:..:.: .::.: :.::.
NP_009 RAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCRVLISTDLTSRGIDAEKVNL
330 340 350 360 370 380
360 370 380 390 400 410
pF1KE1 AFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEI
. : :.: : .::.::..::::::: ::..:. .. ... . .. ..:. ::: :
NP_009 VVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENMMMRIAQKCNINLLPLPDPI
390 400 410 420 430 440
420
pF1KE1 DISSYIEQTR
:. .:.
NP_009 P-SGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQIQKIERTLQIQKAHGDHMASSRNN
450 460 470 480 490
>>NP_057439 (OMIM: 615428) probable ATP-dependent RNA he (455 aa)
initn: 714 init1: 304 opt: 732 Z-score: 877.8 bits: 171.6 E(85289): 3.7e-42
Smith-Waterman score: 732; 33.6% identity (70.7% similar) in 375 aa overlap (47-419:26-394)
20 30 40 50 60 70
pF1KE1 EVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECI
:.:. . : .: . :. .:...: : :
NP_057 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAI
10 20 30 40 50
80 90 100 110 120 130
pF1KE1 PQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERF
: :. : :.. :..: :::..:.: :. : . .. .::. :::::::::...: .
NP_057 PLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEAL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE1 SKYMPNVKVAVFFGGL-SIKKDEEVLKKNCPHIVVGTPGRILA-LARNKSLNLKHIKHFI
.. . .:. ::. ::. :.... . :: :::...::::.. : .:..::. .:...
NP_057 GSSI-GVQSAVIVGGIDSMSQSLALAKK--PHIIIATPGRLIDHLENTKGFNLRALKYLV
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE1 LDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDE
.:: :..:. .:.. .:..:... :.......::::..:... . : ...:.. :...
NP_057 MDEADRILN-MDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSK
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE1 TKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPA
. :.. :::::. . .. :. : .:. : :. .:: .. . : :: . .: :
NP_057 YQ-TVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTA
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE1 IAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHR
: .: : : .::. ..:: : ::.::.. .::.:: .:... :.:.: : :.::
NP_057 IPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHR
300 310 320 330 340 350
380 390 400 410 420
pF1KE1 VARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR
:.:..: : .: :::::. . :..... .. . .. .: . :
NP_057 VGRTARAGRSGKAITFVT-QYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRF
360 370 380 390 400
NP_057 ARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
410 420 430 440 450
428 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:29:58 2016 done: Sat Nov 5 13:29:59 2016
Total Scan time: 8.600 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]