FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1036, 558 aa 1>>>pF1KE1036 558 - 558 aa - 558 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6426+/-0.000834; mu= 16.7163+/- 0.050 mean_var=63.7026+/-12.872, 0's: 0 Z-trim(106.6): 18 B-trim: 158 in 1/48 Lambda= 0.160693 statistics sampled from 9086 (9100) to 9086 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.28), width: 16 Scan time: 3.490 The best scores are: opt bits E(32554) CCDS4713.1 ABHD16A gene_id:7920|Hs108|chr6 ( 558) 3820 894.4 0 CCDS54988.1 ABHD16A gene_id:7920|Hs108|chr6 ( 525) 3250 762.2 0 CCDS13539.1 ABHD16B gene_id:140701|Hs108|chr20 ( 469) 1498 356.0 5.7e-98 >>CCDS4713.1 ABHD16A gene_id:7920|Hs108|chr6 (558 aa) initn: 3820 init1: 3820 opt: 3820 Z-score: 4780.4 bits: 894.4 E(32554): 0 Smith-Waterman score: 3820; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558) 10 20 30 40 50 60 pF1KE1 MAKLLSCVLGPRLYKIYRERDSERAPASVPETPTAVTAPHSSSWDTYYQPRALEKHADSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MAKLLSCVLGPRLYKIYRERDSERAPASVPETPTAVTAPHSSSWDTYYQPRALEKHADSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 LALASVFWSISYYSSPFAFFYLYRKGYLSLSKVVPFSHYAGTLLLLLAGVACLRGIGRWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LALASVFWSISYYSSPFAFFYLYRKGYLSLSKVVPFSHYAGTLLLLLAGVACLRGIGRWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 NPQYRQFITILEATHRNQSSENKRQLANYNFDFRSWPVDFHWEEPSSRKESRGGPSRRGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NPQYRQFITILEATHRNQSSENKRQLANYNFDFRSWPVDFHWEEPSSRKESRGGPSRRGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 ALLRPEPLHRGTADTLLNRVKKLPCQITSYLVAHTLGRRMLYPGSVYLLQKALMPVLLQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ALLRPEPLHRGTADTLLNRVKKLPCQITSYLVAHTLGRRMLYPGSVYLLQKALMPVLLQG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 QARLVEECNGRRAKLLACDGNEIDTMFVDRRGTAEPQGQKLVICCEGNAGFYEVGCVSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QARLVEECNGRRAKLLACDGNEIDTMFVDRRGTAEPQGQKLVICCEGNAGFYEVGCVSTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 LEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVVVQFAIHRLGFQPQDIIIYAWSIGGFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVVVQFAIHRLGFQPQDIIIYAWSIGGFT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 ATWAAMSYPDVSAMILDASFDDLVPLALKVMPDSWRGLVTRTVRQHLNLNNAEQLCRYQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 ATWAAMSYPDVSAMILDASFDDLVPLALKVMPDSWRGLVTRTVRQHLNLNNAEQLCRYQG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 PVLLIRRTKDEIITTTVPEDIMSNRGNDLLLKLLQHRYPRVMAEEGLRVVRQWLEASSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PVLLIRRTKDEIITTTVPEDIMSNRGNDLLLKLLQHRYPRVMAEEGLRVVRQWLEASSQL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 EEASIYSRWEVEEDWCLSVLRSYQAEHGPDFPWSVGEDMSADGRRQLALFLARKHLHNFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 EEASIYSRWEVEEDWCLSVLRSYQAEHGPDFPWSVGEDMSADGRRQLALFLARKHLHNFE 490 500 510 520 530 540 550 pF1KE1 ATHCTPLPAQNFQMPWHL :::::::::::::::::: CCDS47 ATHCTPLPAQNFQMPWHL 550 >>CCDS54988.1 ABHD16A gene_id:7920|Hs108|chr6 (525 aa) initn: 3250 init1: 3250 opt: 3250 Z-score: 4066.7 bits: 762.2 E(32554): 0 Smith-Waterman score: 3250; 100.0% identity (100.0% similar) in 473 aa overlap (86-558:53-525) 60 70 80 90 100 110 pF1KE1 HADSILALASVFWSISYYSSPFAFFYLYRKGYLSLSKVVPFSHYAGTLLLLLAGVACLRG :::::::::::::::::::::::::::::: CCDS54 RSCIRRSSPQPPPNLAWRPESLYSGELAGGGYLSLSKVVPFSHYAGTLLLLLAGVACLRG 30 40 50 60 70 80 120 130 140 150 160 170 pF1KE1 IGRWTNPQYRQFITILEATHRNQSSENKRQLANYNFDFRSWPVDFHWEEPSSRKESRGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IGRWTNPQYRQFITILEATHRNQSSENKRQLANYNFDFRSWPVDFHWEEPSSRKESRGGP 90 100 110 120 130 140 180 190 200 210 220 230 pF1KE1 SRRGVALLRPEPLHRGTADTLLNRVKKLPCQITSYLVAHTLGRRMLYPGSVYLLQKALMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SRRGVALLRPEPLHRGTADTLLNRVKKLPCQITSYLVAHTLGRRMLYPGSVYLLQKALMP 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE1 VLLQGQARLVEECNGRRAKLLACDGNEIDTMFVDRRGTAEPQGQKLVICCEGNAGFYEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VLLQGQARLVEECNGRRAKLLACDGNEIDTMFVDRRGTAEPQGQKLVICCEGNAGFYEVG 210 220 230 240 250 260 300 310 320 330 340 350 pF1KE1 CVSTPLEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVVVQFAIHRLGFQPQDIIIYAWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CVSTPLEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVVVQFAIHRLGFQPQDIIIYAWS 270 280 290 300 310 320 360 370 380 390 400 410 pF1KE1 IGGFTATWAAMSYPDVSAMILDASFDDLVPLALKVMPDSWRGLVTRTVRQHLNLNNAEQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IGGFTATWAAMSYPDVSAMILDASFDDLVPLALKVMPDSWRGLVTRTVRQHLNLNNAEQL 330 340 350 360 370 380 420 430 440 450 460 470 pF1KE1 CRYQGPVLLIRRTKDEIITTTVPEDIMSNRGNDLLLKLLQHRYPRVMAEEGLRVVRQWLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CRYQGPVLLIRRTKDEIITTTVPEDIMSNRGNDLLLKLLQHRYPRVMAEEGLRVVRQWLE 390 400 410 420 430 440 480 490 500 510 520 530 pF1KE1 ASSQLEEASIYSRWEVEEDWCLSVLRSYQAEHGPDFPWSVGEDMSADGRRQLALFLARKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ASSQLEEASIYSRWEVEEDWCLSVLRSYQAEHGPDFPWSVGEDMSADGRRQLALFLARKH 450 460 470 480 490 500 540 550 pF1KE1 LHNFEATHCTPLPAQNFQMPWHL ::::::::::::::::::::::: CCDS54 LHNFEATHCTPLPAQNFQMPWHL 510 520 >>CCDS13539.1 ABHD16B gene_id:140701|Hs108|chr20 (469 aa) initn: 1771 init1: 869 opt: 1498 Z-score: 1872.4 bits: 356.0 E(32554): 5.7e-98 Smith-Waterman score: 1755; 57.3% identity (79.6% similar) in 450 aa overlap (147-558:20-469) 120 130 140 150 160 170 pF1KE1 GRWTNPQYRQFITILEATHRNQSSENKRQLANYNFDFRSWPVDFHWEE------PSSRKE :.:.. ::.::: :.:.. ::.. CCDS13 MCVICFVKALVRVFKIYLTASYTYPFRGWPVAFRWDDVRAVGRSSSHRA 10 20 30 40 180 190 200 210 pF1KE1 SRGGPSRRGVALLRPEPLH-----------RGTADTLLNRVKKLPCQITSYLVAHTLGRR . . :: ::: : : :. :. ::.....:: :..:: .::.::: CCDS13 LTCAAAAAGVWLLRDETLGGDALGRPPRGARSQAQCLLQQLRELPGQLASYALAHSLGRW 50 60 70 80 90 100 220 230 240 250 260 270 pF1KE1 MLYPGSVYLLQKALMPVLLQGQARLVEECNGRRAKLLACDGNEIDTMFVDRRGT--AEPQ ..::::: :. .::.:.: ::: ::::. .::::::.:::::::::::.::: .. . CCDS13 LVYPGSVSLMTRALLPLLQQGQERLVERYHGRRAKLVACDGNEIDTMFMDRRQHPGSHVH 110 120 130 140 150 160 280 290 300 310 320 330 pF1KE1 GQKLVICCEGNAGFYEVGCVSTPLEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVVVQF : .:::::::::::::.::.:.::::::::::::::::..::::::::..::::::::.. CCDS13 GPRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGSSTGVPFPQHDANAMDVVVEY 170 180 190 200 210 220 340 350 360 370 380 390 pF1KE1 AIHRLGFQPQDIIIYAWSIGGFTATWAAMSYPDVSAMILDASFDDLVPLALKVMPDSWRG :.::: : : ...:.::.::::::::.:.::...:..:::.::::::::::::: ::.: CCDS13 ALHRLHFPPAHLVVYGWSVGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKG 230 240 250 260 270 280 400 410 420 430 440 450 pF1KE1 LVTRTVRQHLNLNNAEQLCRYQGPVLLIRRTKDEIITTT------VPEDIMSNRGNDLLL ::.::::.:.::: ::::: : :::::.:::.:....:. : :. .::::.::: CCDS13 LVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSGRLRPLSPGDVEGNRGNELLL 290 300 310 320 330 340 460 470 480 490 500 pF1KE1 KLLQHRYPRVMAEEGLRVVRQWLEASSQLEEASIYSRWEVEEDWCLSVLRSYQAE----- .::.:::: :::.:: :: .::.:.: .::..:.:..:.:::::..::::.:. CCDS13 RLLEHRYPVVMAREGRAVVTRWLRAGSLAQEAAFYARYRVDEDWCLALLRSYRARCEEEL 350 360 370 380 390 400 510 520 530 540 550 pF1KE1 --------HGPDFPWSVGEDMSADGRRQLALFLARKHLHNFEATHCTPLPAQNFQMPWHL ::: ::: ::. .:. ::.::::::::::.: :::: .:: ..::.::.: CCDS13 EGEEALGPHGPAFPWLVGQGLSSRRRRRLALFLARKHLKNVEATHFSPLEPEEFQLPWRL 410 420 430 440 450 460 558 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:40:42 2016 done: Sat Nov 5 07:40:42 2016 Total Scan time: 3.490 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]