FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1037, 387 aa 1>>>pF1KE1037 387 - 387 aa - 387 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4262+/-0.000403; mu= 15.7524+/- 0.025 mean_var=60.5644+/-11.758, 0's: 0 Z-trim(111.5): 28 B-trim: 0 in 0/55 Lambda= 0.164803 statistics sampled from 20053 (20065) to 20053 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.61), E-opt: 0.2 (0.235), width: 16 Scan time: 7.590 The best scores are: opt bits E(85289) XP_005253216 (OMIM: 603312) PREDICTED: gamma-butyr ( 387) 2656 640.2 2.5e-183 XP_016873892 (OMIM: 603312) PREDICTED: gamma-butyr ( 387) 2656 640.2 2.5e-183 XP_005253218 (OMIM: 603312) PREDICTED: gamma-butyr ( 387) 2656 640.2 2.5e-183 NP_003977 (OMIM: 603312) gamma-butyrobetaine dioxy ( 387) 2656 640.2 2.5e-183 XP_005253217 (OMIM: 603312) PREDICTED: gamma-butyr ( 387) 2656 640.2 2.5e-183 XP_011518704 (OMIM: 603312) PREDICTED: gamma-butyr ( 387) 2656 640.2 2.5e-183 XP_011529484 (OMIM: 300777,300872) PREDICTED: trim ( 370) 589 148.7 2.1e-35 NP_060666 (OMIM: 300777,300872) trimethyllysine di ( 421) 586 148.0 3.8e-35 NP_001171726 (OMIM: 300777,300872) trimethyllysine ( 376) 431 111.2 4.3e-24 XP_016885109 (OMIM: 300777,300872) PREDICTED: trim ( 259) 309 82.1 1.7e-15 >>XP_005253216 (OMIM: 603312) PREDICTED: gamma-butyrobet (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: XP_005 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>XP_016873892 (OMIM: 603312) PREDICTED: gamma-butyrobet (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: XP_016 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>XP_005253218 (OMIM: 603312) PREDICTED: gamma-butyrobet (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: XP_005 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>NP_003977 (OMIM: 603312) gamma-butyrobetaine dioxygena (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: NP_003 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>XP_005253217 (OMIM: 603312) PREDICTED: gamma-butyrobet (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: XP_005 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>XP_011518704 (OMIM: 603312) PREDICTED: gamma-butyrobet (387 aa) initn: 2656 init1: 2656 opt: 2656 Z-score: 3412.4 bits: 640.2 E(85289): 2.5e-183 Smith-Waterman score: 2656; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISR 310 320 330 340 350 360 370 380 pF1KE1 HLEGAYADWDVVMSRLRILRQRVENGN ::::::::::::::::::::::::::: XP_011 HLEGAYADWDVVMSRLRILRQRVENGN 370 380 >>XP_011529484 (OMIM: 300777,300872) PREDICTED: trimethy (370 aa) initn: 530 init1: 223 opt: 589 Z-score: 756.7 bits: 148.7 E(85289): 2.1e-35 Smith-Waterman score: 589; 28.1% identity (61.5% similar) in 366 aa overlap (16-379:7-366) 10 20 30 40 50 60 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDV . : : : . . :::::.: ..:: .... :.: . ..:. XP_011 MWVIKEMNQELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASVDL 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 NIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSEL : : . .:. ...:::: : .... .:: : . : . .: .... : .. XP_011 CIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIY--QQA 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 QLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHT :.:..: .. :. .: :.:... ::. . .. .. ::..:.... :.::. XP_011 QVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYGRM 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 WQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQK : . .. ...::: :. ::: ...: :.:..::.:. ::: . .:::: . .. XP_011 WYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQ 170 180 190 200 210 220 250 260 270 280 290 pF1KE1 LKKNNPQAFQILSSTFVDFTDI-GVDYCDFSVQSKHKIIELDD-KGQVVRINFNNATRDT . .. :. :..::.. . : : : . . .... . .. : .:: : . XP_011 VLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRYNNYDRAV 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE1 IFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEI : :: . :. .:.: . .. . :..: :..:: :. .::::.::::. . . XP_011 INTVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTG---- 290 300 310 320 330 340 360 370 380 pF1KE1 SRHLEGAYADWDVVMSRLRILRQRVENGN :.: : : : :.. :.: XP_011 YRQLCGCYLTRDDVLNTARLLGLQA 350 360 370 >>NP_060666 (OMIM: 300777,300872) trimethyllysine dioxyg (421 aa) initn: 530 init1: 223 opt: 586 Z-score: 751.9 bits: 148.0 E(85289): 3.8e-35 Smith-Waterman score: 586; 28.3% identity (62.3% similar) in 353 aa overlap (29-379:71-417) 10 20 30 40 50 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEAL . :::::.: ..:: .... :.: . .. NP_060 WHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASV 50 60 70 80 90 100 60 70 80 90 100 110 pF1KE1 DVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGS :. : : . .:. ...:::: : .... .:: : . : . .: .... : . NP_060 DLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIY--Q 110 120 130 140 150 120 130 140 150 160 170 pF1KE1 ELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYG . :.:..: .. :. .: :.:... ::. . .. .. ::..:.... :.:: NP_060 QAQVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYG 160 170 180 190 200 210 180 190 200 210 220 230 pF1KE1 HTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVC . : . .. ...::: :. ::: ...: :.:..::.:. ::: . .:::: . NP_060 RMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAA 220 230 240 250 260 270 240 250 260 270 280 290 pF1KE1 QKLKKNNPQAFQILSSTFVDFTDI-GVDYCDFSVQSKHKIIELDD-KGQVVRINFNNATR ... .. :. :..::.. . : : : . . .... . .. : .:: : NP_060 EQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRYNNYDR 280 290 300 310 320 330 300 310 320 330 340 350 pF1KE1 DTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGT .: :: . :. .:.: . .. . :..: :..:: :. .::::.::::. . . NP_060 AVINTVPYDVVHRWYTAHRTLTIELRRPENEFWVKLKPGRVLFIDNWRVLHGRECFTG-- 340 350 360 370 380 390 360 370 380 pF1KE1 EISRHLEGAYADWDVVMSRLRILRQRVENGN :.: : : : :.. :.: NP_060 --YRQLCGCYLTRDDVLNTARLLGLQA 400 410 420 >>NP_001171726 (OMIM: 300777,300872) trimethyllysine dio (376 aa) initn: 392 init1: 223 opt: 431 Z-score: 553.5 bits: 111.2 E(85289): 4.3e-24 Smith-Waterman score: 431; 28.9% identity (66.2% similar) in 225 aa overlap (29-253:71-293) 10 20 30 40 50 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEAL . :::::.: ..:: .... :.: . .. NP_001 WHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASV 50 60 70 80 90 100 60 70 80 90 100 110 pF1KE1 DVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGS :. : : . .:. ...:::: : .... .:: : . : . .: .... : . NP_001 DLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIY--Q 110 120 130 140 150 120 130 140 150 160 170 pF1KE1 ELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYG . :.:..: .. :. .: :.:... ::. . .. .. ::..:.... :.:: NP_001 QAQVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYG 160 170 180 190 200 210 180 190 200 210 220 230 pF1KE1 HTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVC . : . .. ...::: :. ::: ...: :.:..::.:. ::: . .:::: . NP_001 RMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAA 220 230 240 250 260 270 240 250 260 270 280 290 pF1KE1 QKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDT ... .. :. :..:: NP_001 EQVLQKAPEEFELLSKVPLKHEYIEDVGECHNHMIGIGPVLNIYPWNKELYLIRLFKEKQ 280 290 300 310 320 330 >>XP_016885109 (OMIM: 300777,300872) PREDICTED: trimethy (259 aa) initn: 259 init1: 183 opt: 309 Z-score: 399.4 bits: 82.1 E(85289): 1.7e-15 Smith-Waterman score: 309; 27.0% identity (63.8% similar) in 185 aa overlap (29-213:71-253) 10 20 30 40 50 pF1KE1 MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEAL . :::::.: ..:: .... :.: . .. XP_016 WHHTASKSLTCAWQQHEDHFELKYANTVMRFDYVWLRDHCRSASCYNSKTHQRSLDTASV 50 60 70 80 90 100 60 70 80 90 100 110 pF1KE1 DVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGS :. : : . .:. ...:::: : .... .:: : . : . .: .... : . XP_016 DLCIKPKTIRLDETTLFFTWPDGHVTKYDLNWLVKNSYEGQKQKVIQPRILWNAEIY--Q 110 120 130 140 150 120 130 140 150 160 170 pF1KE1 ELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYG . :.:..: .. :. .: :.:... ::. . .. .. ::..:.... :.:: XP_016 QAQVPSVDCQSFLETNEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLAERISLIRETIYG 160 170 180 190 200 210 180 190 200 210 220 230 pF1KE1 HTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVC . : . .. ...::: :. ::: ...: : XP_016 RMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGFLAFSY 220 230 240 250 240 250 260 270 280 290 pF1KE1 QKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDT 387 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:41:13 2016 done: Sat Nov 5 07:41:14 2016 Total Scan time: 7.590 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]