Result of FASTA (omim) for pF1KE1038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1038, 672 aa
  1>>>pF1KE1038 672 - 672 aa - 672 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1638+/-0.000454; mu= 15.0101+/- 0.028
 mean_var=79.6404+/-15.983, 0's: 0 Z-trim(110.7): 24  B-trim: 784 in 1/50
 Lambda= 0.143717
 statistics sampled from 19128 (19146) to 19128 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.224), width:  16
 Scan time: 11.200

The best scores are:                                      opt bits E(85289)
NP_060660 (OMIM: 607590,615984) Bardet-Biedl syndr ( 672) 4410 924.7       0
NP_789794 (OMIM: 607590,615984) Bardet-Biedl syndr ( 715) 4410 924.7       0
XP_005263163 (OMIM: 607590,615984) PREDICTED: Bard ( 716) 4398 922.2       0
XP_016863846 (OMIM: 607590,615984) PREDICTED: Bard ( 660) 3310 696.6 7.4e-200
XP_016863847 (OMIM: 607590,615984) PREDICTED: Bard ( 618) 3298 694.1 3.9e-199
XP_011530381 (OMIM: 607590,615984) PREDICTED: Bard ( 731) 3090 651.0 4.4e-186
XP_011530382 (OMIM: 607590,615984) PREDICTED: Bard ( 730) 3079 648.8 2.1e-185
XP_011530383 (OMIM: 607590,615984) PREDICTED: Bard ( 676) 1990 422.9 1.9e-117


>>NP_060660 (OMIM: 607590,615984) Bardet-Biedl syndrome   (672 aa)
 initn: 4410 init1: 4410 opt: 4410  Z-score: 4941.5  bits: 924.7 E(85289):    0
Smith-Waterman score: 4410; 100.0% identity (100.0% similar) in 672 aa overlap (1-672:1-672)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE1 VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE1 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
              610       620       630       640       650       660

              670  
pF1KE1 KKQPAHLERLYG
       ::::::::::::
NP_060 KKQPAHLERLYG
              670  

>>NP_789794 (OMIM: 607590,615984) Bardet-Biedl syndrome   (715 aa)
 initn: 4410 init1: 4410 opt: 4410  Z-score: 4941.1  bits: 924.7 E(85289):    0
Smith-Waterman score: 4410; 100.0% identity (100.0% similar) in 672 aa overlap (1-672:1-672)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE1 VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE1 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_789 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
              610       620       630       640       650       660

              670                                             
pF1KE1 KKQPAHLERLYG                                           
       ::::::::::::                                           
NP_789 KKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA
              670       680       690       700       710     

>>XP_005263163 (OMIM: 607590,615984) PREDICTED: Bardet-B  (716 aa)
 initn: 4396 init1: 3087 opt: 4398  Z-score: 4927.6  bits: 922.2 E(85289):    0
Smith-Waterman score: 4398; 99.9% identity (99.9% similar) in 673 aa overlap (1-672:1-673)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200        210       220       230         
pF1KE1 MYAVEVPGPPTVLALHNGNG-GDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRG
       :::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_005 MYAVEVPGPPTVLALHNGNGVGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRG
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE1 GILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGK
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KE1 DSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQE
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KE1 RENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLD
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KE1 VDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPK
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KE1 TCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGE
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KE1 CVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINE
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KE1 VSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEE
              610       620       630       640       650       660

     660       670                                             
pF1KE1 YKKQPAHLERLYG                                           
       :::::::::::::                                           
XP_005 YKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA
              670       680       690       700       710      

>>XP_016863846 (OMIM: 607590,615984) PREDICTED: Bardet-B  (660 aa)
 initn: 3310 init1: 3310 opt: 3310  Z-score: 3709.0  bits: 696.6 E(85289): 7.4e-200
Smith-Waterman score: 3906; 91.8% identity (91.8% similar) in 672 aa overlap (1-672:1-617)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYAVEVPGPPTVLALHNGNGGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRGG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGKD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQER
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLDV
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPKT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE1 CQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGEC
       ::::::::::::::::::::::::                                    
XP_016 CQVRQYHIKPLSLHQRTHFIDHDR------------------------------------
              490       500                                        

              550       560       570       580       590       600
pF1KE1 VTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
                          :::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------KGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINEV
                             510       520       530       540     

              610       620       630       640       650       660
pF1KE1 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEEY
         550       560       570       580       590       600     

              670                                             
pF1KE1 KKQPAHLERLYG                                           
       ::::::::::::                                           
XP_016 KKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQNALISFFDAA
         610       620       630       640       650       660

>>XP_016863847 (OMIM: 607590,615984) PREDICTED: Bardet-B  (618 aa)
 initn: 3296 init1: 1987 opt: 3298  Z-score: 3696.0  bits: 694.1 E(85289): 3.9e-199
Smith-Waterman score: 3894; 91.7% identity (91.7% similar) in 673 aa overlap (1-672:1-618)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200        210       220       230         
pF1KE1 MYAVEVPGPPTVLALHNGNG-GDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRG
       :::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
XP_016 MYAVEVPGPPTVLALHNGNGVGDSGEDLLFGTSDGKLALIQITTSKPVRKWEIQNEKKRG
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE1 GILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQMLSESVTSIQGGCVGK
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KE1 DSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSLRNELEHLQYKVLQE
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KE1 RENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAIDNVLIQSDVPIDLLD
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KE1 VDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQYGTLQAYVTPRIQPK
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KE1 TCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVVFCLPEVPEKPPAGE
       :::::::::::::::::::::::::                                   
XP_016 TCQVRQYHIKPLSLHQRTHFIDHDR-----------------------------------
              490       500                                        

     540       550       560       570       580       590         
pF1KE1 CVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINE
                           ::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------KGEGVFKSDNISTISILKDVLSKEATKRKINLNISYEINE
                             510       520       530       540     

     600       610       620       630       640       650         
pF1KE1 VSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPEYHCILEEADHLQEE
         550       560       570       580       590       600     

     660       670  
pF1KE1 YKKQPAHLERLYG
       :::::::::::::
XP_016 YKKQPAHLERLYG
         610        

>>XP_011530381 (OMIM: 607590,615984) PREDICTED: Bardet-B  (731 aa)
 initn: 3090 init1: 3090 opt: 3090  Z-score: 3461.8  bits: 651.0 E(85289): 4.4e-186
Smith-Waterman score: 4368; 97.7% identity (97.7% similar) in 688 aa overlap (1-672:1-688)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200                       210       220    
pF1KE1 MYAVEVPGPPTVLALHNGNGG----------------DSGEDLLFGTSDGKLALIQITTS
       :::::::::::::::::::::                :::::::::::::::::::::::
XP_011 MYAVEVPGPPTVLALHNGNGGNQDFIFHKSTMCFNIGDSGEDLLFGTSDGKLALIQITTS
              190       200       210       220       230       240

          230       240       250       260       270       280    
pF1KE1 KPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQM
              250       260       270       280       290       300

          290       300       310       320       330       340    
pF1KE1 LSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISS
              310       320       330       340       350       360

          350       360       370       380       390       400    
pF1KE1 LRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAI
              370       380       390       400       410       420

          410       420       430       440       450       460    
pF1KE1 DNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQ
              430       440       450       460       470       480

          470       480       490       500       510       520    
pF1KE1 YGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWV
              490       500       510       520       530       540

          530       540       550       560       570       580    
pF1KE1 VFCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEA
              550       560       570       580       590       600

          590       600       610       620       630       640    
pF1KE1 TKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIP
              610       620       630       640       650       660

          650       660       670                                  
pF1KE1 EYHCILEEADHLQEEYKKQPAHLERLYG                                
       ::::::::::::::::::::::::::::                                
XP_011 EYHCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYD
              670       680       690       700       710       720

>>XP_011530382 (OMIM: 607590,615984) PREDICTED: Bardet-B  (730 aa)
 initn: 3079 init1: 3079 opt: 3079  Z-score: 3449.5  bits: 648.8 E(85289): 2.1e-185
Smith-Waterman score: 4370; 97.8% identity (97.8% similar) in 687 aa overlap (1-672:1-687)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200                      210       220     
pF1KE1 MYAVEVPGPPTVLALHNGNGG---------------DSGEDLLFGTSDGKLALIQITTSK
       :::::::::::::::::::::               ::::::::::::::::::::::::
XP_011 MYAVEVPGPPTVLALHNGNGGNQDFIFHKSTMCFNSDSGEDLLFGTSDGKLALIQITTSK
              190       200       210       220       230       240

         230       240       250       260       270       280     
pF1KE1 PVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQML
              250       260       270       280       290       300

         290       300       310       320       330       340     
pF1KE1 SESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISSL
              310       320       330       340       350       360

         350       360       370       380       390       400     
pF1KE1 RNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAID
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAID
              370       380       390       400       410       420

         410       420       430       440       450       460     
pF1KE1 NVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQY
              430       440       450       460       470       480

         470       480       490       500       510       520     
pF1KE1 GTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWVV
              490       500       510       520       530       540

         530       540       550       560       570       580     
pF1KE1 FCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEAT
              550       560       570       580       590       600

         590       600       610       620       630       640     
pF1KE1 KRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIPE
              610       620       630       640       650       660

         650       660       670                                   
pF1KE1 YHCILEEADHLQEEYKKQPAHLERLYG                                 
       :::::::::::::::::::::::::::                                 
XP_011 YHCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYDQ
              670       680       690       700       710       720

>>XP_011530383 (OMIM: 607590,615984) PREDICTED: Bardet-B  (676 aa)
 initn: 2085 init1: 1990 opt: 1990  Z-score: 2229.7  bits: 422.9 E(85289): 1.9e-117
Smith-Waterman score: 3864; 89.7% identity (89.7% similar) in 688 aa overlap (1-672:1-633)

               10        20        30        40        50        60
pF1KE1 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLILNRMDYLQVGVTSQKTMKLIPASRHRATQKVVIGDHDGVVMCFGMKKGEAAAVFKT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPGPKIARLELGGVINTPQEKIFIAAASEIRGFTKRGKQFLSFETNLTESIKAMHISGSD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLSASYIYNHYCDCKDQHYYLSGDKINDVICLPVERLSRITPVLACQDRVLRVLQGSDV
              130       140       150       160       170       180

              190       200                       210       220    
pF1KE1 MYAVEVPGPPTVLALHNGNGG----------------DSGEDLLFGTSDGKLALIQITTS
       :::::::::::::::::::::                :::::::::::::::::::::::
XP_011 MYAVEVPGPPTVLALHNGNGGNQDFIFHKSTMCFNIGDSGEDLLFGTSDGKLALIQITTS
              190       200       210       220       230       240

          230       240       250       260       270       280    
pF1KE1 KPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPVRKWEIQNEKKRGGILCIDSFDIVGDGVKDLLVGRDDGMVEVYSFDNANEPVLRFDQM
              250       260       270       280       290       300

          290       300       310       320       330       340    
pF1KE1 LSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSESVTSIQGGCVGKDSYDEIVVSTYSGWVTGLTTEPIHKESGPGEELKINQEMQNKISS
              310       320       330       340       350       360

          350       360       370       380       390       400    
pF1KE1 LRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRNELEHLQYKVLQERENYQQSSQSSKAKSAVPSFGINDKFTLNKDDASYSLILEVQTAI
              370       380       390       400       410       420

          410       420       430       440       450       460    
pF1KE1 DNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNVLIQSDVPIDLLDVDKNSAVVSFSSCDSESNDNFLLATYRCQADTTRLELKIRSIEGQ
              430       440       450       460       470       480

          470       480       490       500       510       520    
pF1KE1 YGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDRPMNTLTLTGQFSFAEVHSWV
       ::::::::::::::::::::::::::::::::::::::::                    
XP_011 YGTLQAYVTPRIQPKTCQVRQYHIKPLSLHQRTHFIDHDR--------------------
              490       500       510       520                    

          530       540       550       560       570       580    
pF1KE1 VFCLPEVPEKPPAGECVTFYFQNTFLDTQLESTYRKGEGVFKSDNISTISILKDVLSKEA
                                          :::::::::::::::::::::::::
XP_011 -----------------------------------KGEGVFKSDNISTISILKDVLSKEA
                                                 530       540     

          590       600       610       620       630       640    
pF1KE1 TKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRKINLNISYEINEVSVKHTLKLIHPKLEYQLLLAKKVQLIDALKELQIHEGNTNFLIP
         550       560       570       580       590       600     

          650       660       670                                  
pF1KE1 EYHCILEEADHLQEEYKKQPAHLERLYG                                
       ::::::::::::::::::::::::::::                                
XP_011 EYHCILEEADHLQEEYKKQPAHLERLYGMITDLFIDKFKFKGTNVKTKVPLLLEILDSYD
         610       620       630       640       650       660     




672 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:41:52 2016 done: Sat Nov  5 07:41:53 2016
 Total Scan time: 11.200 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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