FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1039, 495 aa
  1>>>pF1KE1039 495 - 495 aa - 495 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3547+/-0.000387; mu= 4.4273+/- 0.024
 mean_var=196.0678+/-41.067, 0's: 0 Z-trim(118.1): 55  B-trim: 232 in 1/53
 Lambda= 0.091595
 statistics sampled from 30642 (30700) to 30642 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.36), width:  16
 Scan time: 10.250

The best scores are:                                      opt bits E(85289)
NP_064550 (OMIM: 605256) E3 ubiquitin-protein liga ( 495) 3227 439.2 1.3e-122
XP_016862362 (OMIM: 605256) PREDICTED: E3 ubiquiti ( 409) 2597 355.9 1.3e-97


>>NP_064550 (OMIM: 605256) E3 ubiquitin-protein ligase R  (495 aa)
 initn: 3227 init1: 3227 opt: 3227  Z-score: 2322.4  bits: 439.2 E(85289): 1.3e-122
Smith-Waterman score: 3227; 99.8% identity (100.0% similar) in 495 aa overlap (1-495:1-495)

               10        20        30        40        50        60
pF1KE1 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG
       :.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA
              430       440       450       460       470       480

              490     
pF1KE1 AESAEIEPRNKRNRN
       :::::::::::::::
NP_064 AESAEIEPRNKRNRN
              490     

>>XP_016862362 (OMIM: 605256) PREDICTED: E3 ubiquitin-pr  (409 aa)
 initn: 2597 init1: 2597 opt: 2597  Z-score: 1873.6  bits: 355.9 E(85289): 1.3e-97
Smith-Waterman score: 2597; 99.8% identity (100.0% similar) in 406 aa overlap (90-495:4-409)

      60        70        80        90       100       110         
pF1KE1 CPTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTP
                                     ::::::::::::::::::::::::::::::
XP_016                            MNWNHLLQFALESPAKSPASSSSKNLAVKVYTP
                                          10        20        30   

     120       130       140       150       160       170         
pF1KE1 VASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIA
            40        50        60        70        80        90   

     180       190       200       210       220       230         
pF1KE1 PDPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHK
           100       110       120       130       140       150   

     240       250       260       270       280       290         
pF1KE1 RKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAE
           160       170       180       190       200       210   

     300       310       320       330       340       350         
pF1KE1 IVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARK
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVREIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARK
           220       230       240       250       260       270   

     360       370       380       390       400       410         
pF1KE1 GYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREE
           280       290       300       310       320       330   

     420       430       440       450       460       470         
pF1KE1 DSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTR
           340       350       360       370       380       390   

     480       490     
pF1KE1 AAESAEIEPRNKRNRN
       ::::::::::::::::
XP_016 AAESAEIEPRNKRNRN
           400         




495 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:42:34 2016 done: Sat Nov  5 07:42:36 2016
 Total Scan time: 10.250 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]