FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1041, 350 aa 1>>>pF1KE1041 350 - 350 aa - 350 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1712+/-0.000843; mu= 17.4001+/- 0.051 mean_var=74.2193+/-14.574, 0's: 0 Z-trim(107.9): 61 B-trim: 62 in 1/49 Lambda= 0.148873 statistics sampled from 9799 (9861) to 9799 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.303), width: 16 Scan time: 2.220 The best scores are: opt bits E(32554) CCDS7104.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 350) 2433 531.8 3.3e-151 CCDS53494.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 410) 2433 531.8 3.8e-151 CCDS14304.1 SUV39H1 gene_id:6839|Hs108|chrX ( 412) 1398 309.5 3.1e-84 CCDS65252.1 SUV39H1 gene_id:6839|Hs108|chrX ( 423) 1398 309.5 3.2e-84 CCDS53493.1 SUV39H2 gene_id:79723|Hs108|chr10 ( 230) 864 194.6 6.7e-50 CCDS4726.1 EHMT2 gene_id:10919|Hs108|chr6 (1176) 535 124.5 4.4e-28 CCDS4725.1 EHMT2 gene_id:10919|Hs108|chr6 (1210) 535 124.5 4.5e-28 CCDS75425.1 EHMT2 gene_id:10919|Hs108|chr6 (1233) 535 124.5 4.5e-28 CCDS7050.2 EHMT1 gene_id:79813|Hs108|chr9 (1298) 513 119.8 1.3e-26 CCDS63528.1 SETMAR gene_id:6419|Hs108|chr3 ( 365) 483 113.0 4.1e-25 CCDS2563.2 SETMAR gene_id:6419|Hs108|chr3 ( 684) 483 113.2 6.6e-25 CCDS56517.1 EZH2 gene_id:2146|Hs108|chr7 ( 695) 326 79.5 9.5e-15 CCDS5892.1 EZH2 gene_id:2146|Hs108|chr7 ( 707) 326 79.5 9.6e-15 CCDS56518.1 EZH2 gene_id:2146|Hs108|chr7 ( 737) 326 79.5 1e-14 CCDS56516.1 EZH2 gene_id:2146|Hs108|chr7 ( 746) 326 79.5 1e-14 CCDS5891.1 EZH2 gene_id:2146|Hs108|chr7 ( 751) 326 79.5 1e-14 CCDS2749.2 SETD2 gene_id:29072|Hs108|chr3 (2564) 331 81.0 1.2e-14 CCDS82129.1 EZH1 gene_id:2145|Hs108|chr17 ( 707) 324 79.0 1.3e-14 CCDS82130.1 EZH1 gene_id:2145|Hs108|chr17 ( 738) 324 79.1 1.3e-14 CCDS32659.1 EZH1 gene_id:2145|Hs108|chr17 ( 747) 324 79.1 1.4e-14 CCDS4413.1 NSD1 gene_id:64324|Hs108|chr5 (2427) 324 79.4 3.4e-14 CCDS4412.1 NSD1 gene_id:64324|Hs108|chr5 (2696) 324 79.5 3.6e-14 CCDS33940.1 WHSC1 gene_id:7468|Hs108|chr4 (1365) 306 75.4 3.1e-13 CCDS1113.2 ASH1L gene_id:55870|Hs108|chr1 (2964) 308 76.1 4.2e-13 CCDS43729.1 WHSC1L1 gene_id:54904|Hs108|chr8 (1437) 297 73.5 1.2e-12 CCDS31686.1 KMT2A gene_id:4297|Hs108|chr11 (3969) 276 69.3 6.2e-11 CCDS55791.1 KMT2A gene_id:4297|Hs108|chr11 (3972) 276 69.3 6.2e-11 >>CCDS7104.1 SUV39H2 gene_id:79723|Hs108|chr10 (350 aa) initn: 2433 init1: 2433 opt: 2433 Z-score: 2828.1 bits: 531.8 E(32554): 3.3e-151 Smith-Waterman score: 2433; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350) 10 20 30 40 50 60 pF1KE1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 PAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 ISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 ISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 NRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 GITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 GITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTR 250 260 270 280 290 300 310 320 330 340 350 pF1KE1 TINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS71 TINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 310 320 330 340 350 >>CCDS53494.1 SUV39H2 gene_id:79723|Hs108|chr10 (410 aa) initn: 2433 init1: 2433 opt: 2433 Z-score: 2827.1 bits: 531.8 E(32554): 3.8e-151 Smith-Waterman score: 2433; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:61-410) 10 20 30 pF1KE1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLL :::::::::::::::::::::::::::::: CCDS53 KLTCKSIGITKRNLNNYEVEYLCDYKVVKDMEYYLVKWKGWPDSTNTWEPLQNLKCPLLL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE1 QQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 QQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNH 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE1 KGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLL 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE1 AYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 AYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVK 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE1 IKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 IKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVN 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE1 HSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPA 340 350 360 370 380 390 340 350 pF1KE1 KKRVRTVCKCGAVTCRGYLN :::::::::::::::::::: CCDS53 KKRVRTVCKCGAVTCRGYLN 400 410 >>CCDS14304.1 SUV39H1 gene_id:6839|Hs108|chrX (412 aa) initn: 1429 init1: 925 opt: 1398 Z-score: 1625.7 bits: 309.5 E(32554): 3.1e-84 Smith-Waterman score: 1466; 60.1% identity (77.8% similar) in 361 aa overlap (2-349:58-411) 10 20 30 pF1KE1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ :::::::.:.::: .:::: ::::: .:. CCDS14 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE1 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK :: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...: CCDS14 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL 90 100 110 120 130 140 100 110 120 130 140 pF1KE1 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV : : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. . CCDS14 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH 150 160 170 180 190 200 150 160 170 180 190 200 pF1KE1 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL .::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.:: CCDS14 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL 210 220 230 240 250 260 210 220 230 240 250 260 pF1KE1 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF ::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.::: CCDS14 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF 270 280 290 300 310 320 270 280 290 300 310 320 pF1KE1 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .: CCDS14 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS 330 340 350 360 370 380 330 340 350 pF1KE1 ---------SPAKKRVRTVCKCGAVTCRGYLN :: ::::: ::::. .:: :: CCDS14 NFGLAGLPGSP-KKRVRIECKCGTESCRKYLF 390 400 410 >>CCDS65252.1 SUV39H1 gene_id:6839|Hs108|chrX (423 aa) initn: 1429 init1: 925 opt: 1398 Z-score: 1625.6 bits: 309.5 E(32554): 3.2e-84 Smith-Waterman score: 1466; 60.1% identity (77.8% similar) in 361 aa overlap (2-349:69-422) 10 20 30 pF1KE1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQ :::::::.:.::: .:::: ::::: .:. CCDS65 LSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE1 QFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHK :: .: . : . .. .. ::. : :..:.:.:.::::: ::.::..::: ...: CCDS65 QFHKDLERELLR-RHHRSKTPRH----LDPSLANYLVQKAKQRRALRRWEQELNAKRSHL 100 110 120 130 140 150 100 110 120 130 140 pF1KE1 GMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQK---CCPAEAGV : : ::: :::.::: : :::::. . ::.: :... :: : ::.. :::. . CCDS65 GRITVENEVDLDGPPRAFVYINEYRVGEGITL-NQVAVGCECQDCLWAPTGGCCPGASLH 160 170 180 190 200 210 150 160 170 180 190 200 pF1KE1 LLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTL .::: . :... : :::::::::.:: :::::.:::: .:.::::::..::::::.:: CCDS65 KFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTL 220 230 240 250 260 270 210 220 230 240 250 260 pF1KE1 VKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHF ::.. :::::::::.:::::::::::.:: .: :::::::: : .::::: :::.::: CCDS65 EKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHF 280 290 300 310 320 330 270 280 290 300 310 320 pF1KE1 VNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSG-DISSDSIDH :::::::::::.:::::::: ::::::.:.:::: :::::::::.:. . :. : .: CCDS65 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS 340 350 360 370 380 390 330 340 350 pF1KE1 ---------SPAKKRVRTVCKCGAVTCRGYLN :: ::::: ::::. .:: :: CCDS65 NFGLAGLPGSP-KKRVRIECKCGTESCRKYLF 400 410 420 >>CCDS53493.1 SUV39H2 gene_id:79723|Hs108|chr10 (230 aa) initn: 864 init1: 864 opt: 864 Z-score: 1009.4 bits: 194.6 E(32554): 6.7e-50 Smith-Waterman score: 864; 97.7% identity (100.0% similar) in 131 aa overlap (220-350:100-230) 190 200 210 220 230 240 pF1KE1 YSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLD :...:::::::::::::::::::::::::: CCDS53 GWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVITSEEAERRGQFYDNKGITYLFDLD 70 80 90 100 110 120 250 260 270 280 290 300 pF1KE1 YESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELT 130 140 150 160 170 180 310 320 330 340 350 pF1KE1 FDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN ::::::::::::::::::::::::::::::::::::::::: CCDS53 FDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN 190 200 210 220 230 >-- initn: 293 init1: 293 opt: 293 Z-score: 346.6 bits: 72.0 E(32554): 5.5e-13 Smith-Waterman score: 293; 100.0% identity (100.0% similar) in 39 aa overlap (1-39:61-99) 10 20 30 pF1KE1 MEYYLVKWKGWPDSTNTWEPLQNLKCPLLL :::::::::::::::::::::::::::::: CCDS53 KLTCKSIGITKRNLNNYEVEYLCDYKVVKDMEYYLVKWKGWPDSTNTWEPLQNLKCPLLL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE1 QQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNH ::::::::: CCDS53 QQFSNDKHNYLSQVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVN 100 110 120 130 140 150 >>CCDS4726.1 EHMT2 gene_id:10919|Hs108|chr6 (1176 aa) initn: 460 init1: 233 opt: 535 Z-score: 617.7 bits: 124.5 E(32554): 4.4e-28 Smith-Waterman score: 552; 38.8% identity (62.0% similar) in 258 aa overlap (98-346:905-1142) 70 80 90 100 110 120 pF1KE1 VKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEA : :: : : :. ::.: . ... . CCDS47 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 880 890 900 910 920 930 130 140 150 160 170 pF1KE1 TF--GCSCTD-CFFQKCCPAEAGVLLAYNKNQQI-----KIPPGTPIYECNSRCQCGPDC : :.:.: : ..: .. .. :.:. .. :: : :.:::. :.: .: CCDS47 THLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQACSCWRNC 940 950 960 970 980 990 180 190 200 210 220 230 pF1KE1 PNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDN ::.::.: . : ..::.. ::::..: : . .:. :::::.:.. ::. : :. CCDS47 KNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR---EDD 1000 1010 1020 1030 1040 240 250 260 270 280 290 pF1KE1 KGITYLFDLDYESDE-FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS .:::::: .. : . .:: :::.:.:.:: ::::. ::. . : :.::::.:: CCDS47 ---SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFS 1050 1060 1070 1080 1090 1100 300 310 320 330 340 350 pF1KE1 TRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN .: : .:::: ::: :: : :.. : :.::. :. CCDS47 SRDIRTGEELGFDY-----GDRFWD------IKSKYFT-CQCGSEKCKHSAEAIALEQSR 1110 1120 1130 1140 1150 CCDS47 LARLDPHPELLPELGSLPPVNT 1160 1170 >>CCDS4725.1 EHMT2 gene_id:10919|Hs108|chr6 (1210 aa) initn: 460 init1: 233 opt: 535 Z-score: 617.5 bits: 124.5 E(32554): 4.5e-28 Smith-Waterman score: 552; 38.8% identity (62.0% similar) in 258 aa overlap (98-346:939-1176) 70 80 90 100 110 120 pF1KE1 VKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEA : :: : : :. ::.: . ... . CCDS47 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 910 920 930 940 950 960 130 140 150 160 170 pF1KE1 TF--GCSCTD-CFFQKCCPAEAGVLLAYNKNQQI-----KIPPGTPIYECNSRCQCGPDC : :.:.: : ..: .. .. :.:. .. :: : :.:::. :.: .: CCDS47 THLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQACSCWRNC 970 980 990 1000 1010 1020 180 190 200 210 220 230 pF1KE1 PNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDN ::.::.: . : ..::.. ::::..: : . .:. :::::.:.. ::. : :. CCDS47 KNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR---EDD 1030 1040 1050 1060 1070 1080 240 250 260 270 280 290 pF1KE1 KGITYLFDLDYESDE-FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS .:::::: .. : . .:: :::.:.:.:: ::::. ::. . : :.::::.:: CCDS47 ---SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFS 1090 1100 1110 1120 1130 1140 300 310 320 330 340 350 pF1KE1 TRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN .: : .:::: ::: :: : :.. : :.::. :. CCDS47 SRDIRTGEELGFDY-----GDRFWD------IKSKYFT-CQCGSEKCKHSAEAIALEQSR 1150 1160 1170 1180 CCDS47 LARLDPHPELLPELGSLPPVNT 1190 1200 1210 >>CCDS75425.1 EHMT2 gene_id:10919|Hs108|chr6 (1233 aa) initn: 460 init1: 233 opt: 535 Z-score: 617.4 bits: 124.5 E(32554): 4.5e-28 Smith-Waterman score: 552; 38.8% identity (62.0% similar) in 258 aa overlap (98-346:962-1199) 70 80 90 100 110 120 pF1KE1 VKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEA : :: : : :. ::.: . ... . CCDS75 LGVGNRAIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNI 940 950 960 970 980 990 130 140 150 160 170 pF1KE1 TF--GCSCTD-CFFQKCCPAEAGVLLAYNKNQQI-----KIPPGTPIYECNSRCQCGPDC : :.:.: : ..: .. .. :.:. .. :: : :.:::. :.: .: CCDS75 THLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPL-IFECNQACSCWRNC 1000 1010 1020 1030 1040 1050 180 190 200 210 220 230 pF1KE1 PNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDN ::.::.: . : ..::.. ::::..: : . .:. :::::.:.. ::. : :. CCDS75 KNRVVQSGIKVRLQLYRTAK-MGWGVRALQTIPQGTFICEYVGELISDAEADVR---EDD 1060 1070 1080 1090 1100 240 250 260 270 280 290 pF1KE1 KGITYLFDLDYESDE-FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS .:::::: .. : . .:: :::.:.:.:: ::::. ::. . : :.::::.:: CCDS75 ---SYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFS 1110 1120 1130 1140 1150 1160 300 310 320 330 340 350 pF1KE1 TRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN .: : .:::: ::: :: : :.. : :.::. :. CCDS75 SRDIRTGEELGFDY-----GDRFWD------IKSKYFT-CQCGSEKCKHSAEAIALEQSR 1170 1180 1190 1200 1210 CCDS75 LARLDPHPELLPELGSLPPVNT 1220 1230 >>CCDS7050.2 EHMT1 gene_id:79813|Hs108|chr9 (1298 aa) initn: 480 init1: 238 opt: 513 Z-score: 591.6 bits: 119.8 E(32554): 1.3e-26 Smith-Waterman score: 526; 38.4% identity (61.6% similar) in 258 aa overlap (98-346:1027-1264) 70 80 90 100 110 120 pF1KE1 VKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEA :.:: : ::.. :... . ... . CCDS70 DSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNI 1000 1010 1020 1030 1040 1050 130 140 150 160 170 pF1KE1 TF--GCSCTD-CFFQKCCPAEAGVLLAYNKNQQIKIPP---GTP--IYECNSRCQCGPDC : : : : : ..: .. .. :.:. .. .: . : :.::: :.: .: CCDS70 THLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRL-LPEFNMAEPPLIFECNHACSCWRNC 1060 1070 1080 1090 1100 1110 180 190 200 210 220 230 pF1KE1 PNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDN ::.::.: . : ..:: . ::::..: : .:: :::::.:.. ::. : . : CCDS70 RNRVVQNGLRARLQLYRTRD-MGWGVRSLQDIPPGTFVCEYVGELISDSEADVREE--D- 1120 1130 1140 1150 1160 1170 240 250 260 270 280 290 pF1KE1 KGITYLFDLDYESDE-FTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS .:::::: .. : . .:: :::::.:.:: :.::: ::. . : :.::::.:: CCDS70 ---SYLFDLDNKDGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFS 1180 1190 1200 1210 1220 300 310 320 330 340 350 pF1KE1 TRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN :: :.:::.: ::: . :: : .. . :.::. :: CCDS70 TRLIEAGEQLGFDYGER-FWDI----------KGKLFS-CRCGSPKCRHSSAALAQRQAS 1230 1240 1250 1260 1270 CCDS70 AAQEAQEDGLPDTSSAAAADPL 1280 1290 >>CCDS63528.1 SETMAR gene_id:6419|Hs108|chr3 (365 aa) initn: 250 init1: 145 opt: 483 Z-score: 564.3 bits: 113.0 E(32554): 4.1e-25 Smith-Waterman score: 483; 34.1% identity (62.1% similar) in 261 aa overlap (106-349:48-298) 80 90 100 110 120 130 pF1KE1 ALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISL-VNEATF-GCSC :. : : .. .:: .. .. :: :: : CCDS63 KEKPEAPTEQLDVACGQENLPVGAWPPGAAPAPFQYTPDHVVGPGADIDPTQITFPGCIC 20 30 40 50 60 70 140 150 160 170 180 pF1KE1 --TDCFFQKCCPAEAGVLLAYNKNQQIK-IPPG----TPIYECNSRCQCGPDCPNRIVQK : :. : . : :. :. .. : : :..::: :.:. : ::.::: CCDS63 VKTPCLPGTCSCLRHGE--NYDDNSCLRDIGSGGKYAEPVFECNVLCRCSDHCRNRVVQK 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE1 GTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLF : :. . .:.: . .:::..:: : . :: ::.:::. :..:: .. .. .:.. CCDS63 GLQFHFQVFKTHK-KGWGLRTLEFIPKGRFVCEYAGEVLGFSEVQRRIHLQTKSDSNYII 140 150 160 170 180 190 250 260 270 280 290 300 pF1KE1 DLD---YESD--EFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRT . :... : :: . ::...:.::::.::: .. : ::.. .:..:::... CCDS63 AIREHVYNGQVMETFVDPTYIGNIGRFLNHSCEPNLLMIPVRIDSM---VPKLALFAAKD 200 210 220 230 240 250 310 320 330 340 350 pF1KE1 INAGEELTFDYQMKGSG-DISSDS--IDHSPAKKRVRTVCKCGAVTCRGYLN : :::..::. . . .: :. .::. ..: : ::: .: ..: CCDS63 IVPEEELSYDYSGRYLNLTVSEDKERLDHG----KLRKPCYCGAKSCTAFLPFDSSLYCP 260 270 280 290 300 CCDS63 VEKSNISCGNEKEPSMCGSAPSVFPSCKRLTLEVSLFSDKQLAPPYSGRQWLASFTSA 310 320 330 340 350 360 350 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:43:42 2016 done: Sat Nov 5 07:43:42 2016 Total Scan time: 2.220 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]