Result of FASTA (omim) for
pF1KE1042
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1042, 501 aa
1>>>pF1KE1042 501 - 501 aa - 501 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7393+/-0.000511; mu= 8.6891+/- 0.031
mean_var=296.6755+/-71.353, 0's: 0 Z-trim(116.0): 42 B-trim: 0 in 0/54
Lambda= 0.074462
statistics sampled from 26759 (26799) to 26759 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.314), width: 16
Scan time: 10.200
The best scores are: opt bits E(85289)
XP_011517279 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
XP_011517280 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
XP_011517278 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
NP_066961 (OMIM: 601895) TNF receptor-associated f ( 501) 3465 386.6 9.2e-107
XP_016870584 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
XP_011517276 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
XP_011517277 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 3465 386.6 9.2e-107
XP_016870583 (OMIM: 601895) PREDICTED: TNF recepto ( 533) 3465 386.6 9.5e-107
XP_011517275 (OMIM: 601895) PREDICTED: TNF recepto ( 556) 3465 386.6 9.7e-107
XP_011535418 (OMIM: 601896,614849) PREDICTED: TNF ( 516) 952 116.6 1.7e-25
NP_005649 (OMIM: 601711) TNF receptor-associated f ( 416) 879 108.7 3.5e-23
NP_001177874 (OMIM: 601711) TNF receptor-associate ( 416) 879 108.7 3.5e-23
NP_001177876 (OMIM: 601711) TNF receptor-associate ( 294) 871 107.6 5.2e-23
XP_011535419 (OMIM: 601896,614849) PREDICTED: TNF ( 512) 838 104.4 8.3e-22
NP_001186356 (OMIM: 601896,614849) TNF receptor-as ( 485) 776 97.7 8.2e-20
XP_011535420 (OMIM: 601896,614849) PREDICTED: TNF ( 485) 776 97.7 8.2e-20
XP_016877108 (OMIM: 601896,614849) PREDICTED: TNF ( 543) 766 96.7 1.8e-19
NP_663778 (OMIM: 601896,614849) TNF receptor-assoc ( 543) 766 96.7 1.8e-19
NP_663777 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 729 92.7 3e-18
XP_016877106 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 729 92.7 3e-18
XP_016877107 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 729 92.7 3e-18
NP_003291 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 729 92.7 3e-18
XP_016857710 (OMIM: 602356) PREDICTED: TNF recepto ( 557) 707 90.4 1.5e-17
NP_001029082 (OMIM: 602356) TNF receptor-associate ( 557) 707 90.4 1.5e-17
NP_665702 (OMIM: 602356) TNF receptor-associated f ( 557) 707 90.4 1.5e-17
NP_004610 (OMIM: 602356) TNF receptor-associated f ( 557) 707 90.4 1.5e-17
XP_011508261 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 689 88.4 5.8e-17
XP_011508262 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 689 88.4 5.8e-17
NP_001306136 (OMIM: 602356) TNF receptor-associate ( 568) 689 88.4 5.8e-17
XP_011508259 (OMIM: 602356) PREDICTED: TNF recepto ( 631) 689 88.5 6.2e-17
XP_011523808 (OMIM: 602464) PREDICTED: TNF recepto ( 454) 416 59.0 3.4e-08
XP_011523807 (OMIM: 602464) PREDICTED: TNF recepto ( 461) 416 59.0 3.5e-08
NP_004286 (OMIM: 602464) TNF receptor-associated f ( 470) 416 59.0 3.5e-08
XP_011523806 (OMIM: 602464) PREDICTED: TNF recepto ( 477) 416 59.0 3.5e-08
XP_011523810 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 405 57.6 6.7e-08
XP_011523809 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 405 57.6 6.7e-08
NP_004611 (OMIM: 602355) TNF receptor-associated f ( 522) 399 57.2 1.3e-07
NP_665802 (OMIM: 602355) TNF receptor-associated f ( 522) 399 57.2 1.3e-07
XP_016877109 (OMIM: 601896,614849) PREDICTED: TNF ( 292) 340 50.5 7.7e-06
>>XP_011517279 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_011 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_011517280 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_011 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_011517278 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_011 KNSYVRDDAIFIKAIVDLTGL
490 500
>>NP_066961 (OMIM: 601895) TNF receptor-associated facto (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
NP_066 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_016870584 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_016 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_011517276 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_011 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_011517277 (OMIM: 601895) PREDICTED: TNF receptor-as (501 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.7 bits: 386.6 E(85289): 9.2e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:1-501)
10 20 30 40 50 60
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEA
430 440 450 460 470 480
490 500
pF1KE1 KNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::
XP_011 KNSYVRDDAIFIKAIVDLTGL
490 500
>>XP_016870583 (OMIM: 601895) PREDICTED: TNF receptor-as (533 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.5 bits: 386.6 E(85289): 9.5e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:33-533)
10 20 30
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEA
::::::::::::::::::::::::::::::
XP_016 LEGLQGSLKLCDSASLSLDRRALFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 KYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 FPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKER
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 HLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 KCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 RCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKM
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE1 CLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPD
430 440 450 460 470 480
460 470 480 490 500
pF1KE1 VTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
490 500 510 520 530
>>XP_011517275 (OMIM: 601895) PREDICTED: TNF receptor-as (556 aa)
initn: 3465 init1: 3465 opt: 3465 Z-score: 2037.3 bits: 386.6 E(85289): 9.7e-107
Smith-Waterman score: 3465; 100.0% identity (100.0% similar) in 501 aa overlap (1-501:56-556)
10 20 30
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEA
::::::::::::::::::::::::::::::
XP_011 WESPELRHGQSESPLSSQQTRALFAGVTALMAAASVTPPGSLELLQPGFSKTLLGTKLEA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 KYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSA
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 FPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKER
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 HLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 KCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQ
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 RCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGL
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKM
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE1 CLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPD
450 460 470 480 490 500
460 470 480 490 500
pF1KE1 VTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
510 520 530 540 550
>>XP_011535418 (OMIM: 601896,614849) PREDICTED: TNF rece (516 aa)
initn: 840 init1: 495 opt: 952 Z-score: 578.6 bits: 116.6 E(85289): 1.7e-25
Smith-Waterman score: 989; 35.1% identity (62.5% similar) in 502 aa overlap (16-501:36-513)
10 20 30 40
pF1KE1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPF
: :... .. : .: :: : :. :: :
XP_011 KMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKT-VEDKYKCEKCHLVLCSPK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 QAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPA
:..::::.: :.:..:::. .:.:: .:.: .. . : :: .::. .:
XP_011 QTECGHRFCESCMAALLSSSSPKCTAC-QESIVKDKV--------FKDNCCKREILALQI
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 VC--PSDGCTWKGTLKEYESCHEGRCPLMLTEC--PACKGLVRLGEKERHLEHECPERSL
: : ::. . : . .. : . : : :: : . . :.:. : :
XP_011 YCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREA
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 SCRHCRA--PCC---GAD--VKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRV
.: ::.. : :.. .:::. .. .... .. . .. : .
XP_011 TCSHCKSQVPMIALQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE1 PCRFHAIGCLETVEGEKQQE----HEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQ
.: : .: :.:.: .: . : :: ...: : : . . . .
XP_011 IQSLHNQICSFEIEIERQKEMLRNNESKIL--HLQRVIDSQAEKLKELDKEIRPFRQNWE
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE1 RCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGL
. .:..... ...: : :.: : .: .:. : : :.... .. ...
XP_011 EADSMKSSVESLQNRVT----ELESVDKSAGQVARNTGL-------LESQLSRHDQMLSV
300 310 320 330 340
340 350 360 370 380 390
pF1KE1 KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKM
.:. .::.. . .:...:.::.:::: :. :..:::: :. ...: :::. .::::
XP_011 HDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKM
350 360 370 380 390 400
400 410 420 430 440
pF1KE1 CLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRP
: :.:::::: :.:::::::::.:.: :::: :::.:::::::.:: ..:.:. :::.:
XP_011 CARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKP
410 420 430 440 450 460
450 460 470 480 490 500
pF1KE1 DVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
: .::::..:...::::::::.: . .: ...:..::.::::.::: . :
XP_011 DPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDTSDLPDP
470 480 490 500 510
501 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:44:19 2016 done: Sat Nov 5 07:44:21 2016
Total Scan time: 10.200 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]