FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1043, 470 aa 1>>>pF1KE1043 470 - 470 aa - 470 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.0037+/-0.00121; mu= 1.4975+/- 0.071 mean_var=374.1902+/-99.805, 0's: 0 Z-trim(111.0): 71 B-trim: 533 in 1/49 Lambda= 0.066302 statistics sampled from 12016 (12060) to 12016 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.37), width: 16 Scan time: 3.350 The best scores are: opt bits E(32554) CCDS11243.1 TRAF4 gene_id:9618|Hs108|chr17 ( 470) 3397 339.5 4.5e-93 CCDS7901.1 TRAF6 gene_id:7189|Hs108|chr11 ( 522) 641 76.0 1.1e-13 >>CCDS11243.1 TRAF4 gene_id:9618|Hs108|chr17 (470 aa) initn: 3397 init1: 3397 opt: 3397 Z-score: 1784.4 bits: 339.5 E(32554): 4.5e-93 Smith-Waterman score: 3397; 100.0% identity (100.0% similar) in 470 aa overlap (1-470:1-470) 10 20 30 40 50 60 pF1KE1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 AQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 AQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS 430 440 450 460 470 >>CCDS7901.1 TRAF6 gene_id:7189|Hs108|chr11 (522 aa) initn: 711 init1: 143 opt: 641 Z-score: 359.2 bits: 76.0 E(32554): 1.1e-13 Smith-Waterman score: 746; 26.7% identity (58.0% similar) in 469 aa overlap (1-462:53-499) 10 20 30 pF1KE1 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQ . :.: .: . . ::.: .:: :: CCDS79 MASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQ 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE1 VSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGC . :::::: .:. . . .. ::: :. : ...:: . ..:.: ..: .::: CCDS79 -TPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKC--PNEGC 90 100 110 120 130 100 110 120 130 140 150 pF1KE1 RWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSG . ::::. : : : .. :: .: ... . :. .:::.:...:. :. ... CCDS79 LHKMELRHLEDHQAHCEFALMDCP-QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAF 140 150 160 170 180 190 160 170 180 190 200 pF1KE1 EAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTY----CTKEFVFDT : : :. :: .: :: :.. ..:. . .: .:: :::. : ... . CCDS79 EDKEIHDQNCPLANVICEY-CNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNH 200 210 220 230 240 250 210 220 230 240 250 260 pF1KE1 IQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCP-KLA . : . . . : .: ... :.... : :... :. .:. CCDS79 LARHLQENTQSHMRMLAQ-AVHSLSVIPDSGYISEVRN-------FQET--IHQLEGRLV 260 270 280 290 300 270 280 290 300 310 320 pF1KE1 MARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGS-DGVLIWKIGSYGRRLQEA : . . .. . ::. .. .. :. .. :. . . .:. :::::..: .:. CCDS79 RQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQ 310 320 330 340 350 360 330 340 350 360 370 380 pF1KE1 KAKPNLECFSPAFYTHKYGYKLQVSAFLN-GNGSGEGTHLSLYIRVLPGAFDNLLEWPFA . . . ::.::: : :::: . :. ... ....::..... : .:. : ::: CCDS79 EEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KE1 RRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQ . ...::::. . . .: : . :. ::.: .. .. :::: :. . CCDS79 GTIRLTILDQSEAPV-RQNH-EEIMDAKPELLAFQRP-----TIPRNPKGFGYVTFMHLE 430 440 450 460 470 480 450 460 470 pF1KE1 DIRKRNYVRDDAVFIRAAVELPRKILS .:.:....::....: : CCDS79 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV 490 500 510 520 470 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:44:54 2016 done: Sat Nov 5 07:44:54 2016 Total Scan time: 3.350 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]