FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1046, 145 aa
  1>>>pF1KE1046 145 - 145 aa - 145 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8627+/-0.00034; mu= 13.4444+/- 0.021
 mean_var=55.1373+/-11.203, 0's: 0 Z-trim(113.4): 21  B-trim: 0 in 0/50
 Lambda= 0.172723
 statistics sampled from 22749 (22769) to 22749 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.267), width:  16
 Scan time:  4.900

The best scores are:                                      opt bits E(85289)
NP_001160093 (OMIM: 610969) trafficking protein pa ( 145)  977 251.2 4.4e-67
NP_067033 (OMIM: 610969) trafficking protein parti ( 145)  977 251.2 4.4e-67
NP_057230 (OMIM: 610971) trafficking protein parti ( 219)  167 49.4 3.6e-06
NP_001305419 (OMIM: 610971) trafficking protein pa ( 176)  157 46.9 1.7e-05
NP_001305421 (OMIM: 610971) trafficking protein pa ( 114)  154 46.0   2e-05
NP_001305418 (OMIM: 610971) trafficking protein pa ( 165)  136 41.6  0.0006


>>NP_001160093 (OMIM: 610969) trafficking protein partic  (145 aa)
 initn: 977 init1: 977 opt: 977  Z-score: 1325.3  bits: 251.2 E(85289): 4.4e-67
Smith-Waterman score: 977; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)

               10        20        30        40        50        60
pF1KE1 MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 FLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQT
               70        80        90       100       110       120

              130       140     
pF1KE1 VQSELFRSRLDSYVRSLPFFSARAG
       :::::::::::::::::::::::::
NP_001 VQSELFRSRLDSYVRSLPFFSARAG
              130       140     

>>NP_067033 (OMIM: 610969) trafficking protein particle   (145 aa)
 initn: 977 init1: 977 opt: 977  Z-score: 1325.3  bits: 251.2 E(85289): 4.4e-67
Smith-Waterman score: 977; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145)

               10        20        30        40        50        60
pF1KE1 MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 FLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 FLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQT
               70        80        90       100       110       120

              130       140     
pF1KE1 VQSELFRSRLDSYVRSLPFFSARAG
       :::::::::::::::::::::::::
NP_067 VQSELFRSRLDSYVRSLPFFSARAG
              130       140     

>>NP_057230 (OMIM: 610971) trafficking protein particle   (219 aa)
 initn: 138 init1: 106 opt: 167  Z-score: 231.8  bits: 49.4 E(85289): 3.6e-06
Smith-Waterman score: 167; 34.3% identity (67.6% similar) in 105 aa overlap (28-130:99-202)

                  10        20        30         40         50     
pF1KE1    MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPK-EEEYKLMYGMLF-SIRSFVSKMSPL
                                     : :.   . ::: . .: :. .. :..:: 
NP_057 MDVNGRYTADGKEVLEYLGNPANYPVSIRFGRPRLTSNEKLMLASMFHSLFAIGSQLSPE
       70        80        90       100       110       120        

          60        70        80        90       100       110     
pF1KE1 DMKDGFLAFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLC
       . ..:.  ..:. .::: :.: :::: :. .:   . : ..:..::  .: ....:::. 
NP_057 QGSSGIEMLETDTFKLHCYQTLTGIKFVVLADPRQAGIDSLLRKIYE-IYSDFALKNPFY
      130       140       150       160       170        180       

         120       130       140       
pF1KE1 PLGQTVQSELFRSRLDSYVRSLPFFSARAG  
        : . .. ::: . :                 
NP_057 SLEMPIRCELFDQNLKLALEVAEKAGTFGPGS
       190       200       210         

>>NP_001305419 (OMIM: 610971) trafficking protein partic  (176 aa)
 initn: 138 init1: 106 opt: 157  Z-score: 219.8  bits: 46.9 E(85289): 1.7e-05
Smith-Waterman score: 157; 36.3% identity (68.1% similar) in 91 aa overlap (40-130:73-159)

      10        20        30        40        50        60         
pF1KE1 DRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLAFQTSRY
                                     : ::.: :   ..:: . ..:.  ..:. .
NP_001 HDERVLVAFGQRDGIRVGHAVLAINGMDVNGRLFAIGS---QLSPEQGSSGIEMLETDTF
             50        60        70        80           90         

      70        80        90       100       110       120         
pF1KE1 KLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQTVQSELFRSR
       ::: :.: :::: :. .:   . : ..:..::  .: ....:::.  : . .. ::: . 
NP_001 KLHCYQTLTGIKFVVLADPRQAGIDSLLRKIYE-IYSDFALKNPFYSLEMPIRCELFDQN
     100       110       120       130        140       150        

     130       140       
pF1KE1 LDSYVRSLPFFSARAG  
       :                 
NP_001 LKLALEVAEKAGTFGPGS
      160       170      

>>NP_001305421 (OMIM: 610971) trafficking protein partic  (114 aa)
 initn: 138 init1: 106 opt: 154  Z-score: 218.6  bits: 46.0 E(85289): 2e-05
Smith-Waterman score: 154; 34.1% identity (69.3% similar) in 88 aa overlap (43-130:11-97)

             20        30        40        50        60        70  
pF1KE1 GVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLAFQTSRYKLH
                                     : . .. :..:: . ..:.  ..:. .:::
NP_001                     MKNATDPDLDFRLFAIGSQLSPEQGSSGIEMLETDTFKLH
                                   10        20        30        40

             80        90       100       110       120       130  
pF1KE1 YYETPTGIKVVMNTDLGVGPIRDVLHHIYSALYVELVVKNPLCPLGQTVQSELFRSRLDS
        :.: :::: :. .:   . : ..:..::  .: ....:::.  : . .. ::: . :  
NP_001 CYQTLTGIKFVVLADPRQAGIDSLLRKIYE-IYSDFALKNPFYSLEMPIRCELFDQNLKL
               50        60        70         80        90         

            140       
pF1KE1 YVRSLPFFSARAG  
                      
NP_001 ALEVAEKAGTFGPGS
     100       110    

>>NP_001305418 (OMIM: 610971) trafficking protein partic  (165 aa)
 initn: 123 init1:  91 opt: 136  Z-score: 191.9  bits: 41.6 E(85289): 0.0006
Smith-Waterman score: 136; 37.5% identity (68.1% similar) in 72 aa overlap (59-130:78-148)

       30        40        50        60        70        80        
pF1KE1 IPKEEEYKLMYGMLFSIRSFVSKMSPLDMKDGFLAFQTSRYKLHYYETPTGIKVVMNTDL
                                     ::   ..:. .::: :.: :::: :. .: 
NP_001 LVAFGQRDGIRVGHAVLAINGMDVNGRYTADGKEMLETDTFKLHCYQTLTGIKFVVLADP
        50        60        70        80        90       100       

       90       100       110       120       130       140       
pF1KE1 GVGPIRDVLHHIYSALYVELVVKNPLCPLGQTVQSELFRSRLDSYVRSLPFFSARAG  
         . : ..:..::  .: ....:::.  : . .. ::: . :                 
NP_001 RQAGIDSLLRKIYE-IYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPGS
       110       120        130       140       150       160     




145 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 07:46:21 2016 done: Sat Nov  5 07:46:22 2016
 Total Scan time:  4.900 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]