FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1047, 346 aa 1>>>pF1KE1047 346 - 346 aa - 346 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4894+/-0.000788; mu= 15.5041+/- 0.047 mean_var=68.8060+/-14.061, 0's: 0 Z-trim(108.8): 24 B-trim: 394 in 1/49 Lambda= 0.154618 statistics sampled from 10414 (10429) to 10414 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.32), width: 16 Scan time: 2.850 The best scores are: opt bits E(32554) CCDS9984.1 XRCC3 gene_id:7517|Hs108|chr14 ( 346) 2281 517.5 6.2e-147 CCDS9790.1 RAD51B gene_id:5890|Hs108|chr14 ( 350) 315 79.0 6.5e-15 CCDS9789.1 RAD51B gene_id:5890|Hs108|chr14 ( 384) 315 79.0 7.1e-15 CCDS81815.1 RAD51B gene_id:5890|Hs108|chr14 ( 425) 315 79.0 7.7e-15 >>CCDS9984.1 XRCC3 gene_id:7517|Hs108|chr14 (346 aa) initn: 2281 init1: 2281 opt: 2281 Z-score: 2751.4 bits: 517.5 E(32554): 6.2e-147 Smith-Waterman score: 2281; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346) 10 20 30 40 50 60 pF1KE1 MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 SILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 SILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 CLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 CLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 IEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 TLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS99 TLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADR 250 260 270 280 290 300 310 320 330 340 pF1KE1 LREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH :::::::::::::::::::::::::::::::::::::::::::::: CCDS99 LREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH 310 320 330 340 >>CCDS9790.1 RAD51B gene_id:5890|Hs108|chr14 (350 aa) initn: 282 init1: 164 opt: 315 Z-score: 381.2 bits: 79.0 E(32554): 6.5e-15 Smith-Waterman score: 339; 27.4% identity (57.0% similar) in 351 aa overlap (3-337:6-342) 10 20 30 40 50 pF1KE1 MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHL : . :. .. ... .. . .. : .: .: ..:.:: : .:: .: . CCDS97 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVS-RA 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 RGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLA . .. :: .. :. . :: .:: :.::. ..::..: . ::::. CCDS97 CAPKMQTAYGIKAQRSA-DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 LQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQ-PRLRTDVPGELLQKLRFG ... . . .: . ::::...::: ::.:: .:: .. .. :: . :: . CCDS97 IMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTS---- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE1 SQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASA---PRAR :.. . . : .:. ... ..:.:. .::..::::. : :::.: .. : . CCDS97 SKVHLYRELTCDEVLQRIESLEEEIISKGI-KLVILDSVASVVRKEFDAQLQGNLKERNK 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 HLQSLGATLRELSSAFQSPVLCINQVTE----AMEEQGAAHGP---LGFWDER-----VS : ...:. :. :. ::. ::.: :. :. .: :.. . : CCDS97 FLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE1 PALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTP ::: ::.... .::. . : :. : . . ..: : .: :::. ::. CCDS97 AALGNTWSHSVNTRLILQYLDSER-------RQILIAKSPLAPFTSFVYTIKEEGLVLQG 300 310 320 330 340 pF1KE1 GTQSH CCDS97 QEKP 350 >>CCDS9789.1 RAD51B gene_id:5890|Hs108|chr14 (384 aa) initn: 282 init1: 164 opt: 315 Z-score: 380.6 bits: 79.0 E(32554): 7.1e-15 Smith-Waterman score: 339; 27.4% identity (57.0% similar) in 351 aa overlap (3-337:6-342) 10 20 30 40 50 pF1KE1 MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHL : . :. .. ... .. . .. : .: .: ..:.:: : .:: .: . CCDS97 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVS-RA 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 RGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLA . .. :: .. :. . :: .:: :.::. ..::..: . ::::. CCDS97 CAPKMQTAYGIKAQRSA-DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 LQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQ-PRLRTDVPGELLQKLRFG ... . . .: . ::::...::: ::.:: .:: .. .. :: . :: . CCDS97 IMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTS---- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE1 SQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASA---PRAR :.. . . : .:. ... ..:.:. .::..::::. : :::.: .. : . CCDS97 SKVHLYRELTCDEVLQRIESLEEEIISKGI-KLVILDSVASVVRKEFDAQLQGNLKERNK 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 HLQSLGATLRELSSAFQSPVLCINQVTE----AMEEQGAAHGP---LGFWDER-----VS : ...:. :. :. ::. ::.: :. :. .: :.. . : CCDS97 FLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE1 PALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTP ::: ::.... .::. . : :. : . . ..: : .: :::. ::. CCDS97 AALGNTWSHSVNTRLILQYLDSER-------RQILIAKSPLAPFTSFVYTIKEEGLVLQE 300 310 320 330 340 pF1KE1 GTQSH CCDS97 TTFCSVTQAELNWAPEILPPQPPEQLGLQMCHHTQLIF 350 360 370 380 >>CCDS81815.1 RAD51B gene_id:5890|Hs108|chr14 (425 aa) initn: 287 init1: 164 opt: 315 Z-score: 379.9 bits: 79.0 E(32554): 7.7e-15 Smith-Waterman score: 339; 27.4% identity (57.0% similar) in 351 aa overlap (3-337:6-342) 10 20 30 40 50 pF1KE1 MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHL : . :. .. ... .. . .. : .: .: ..:.:: : .:: .: . CCDS81 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELLCMVS-RA 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 RGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLA . .. :: .. :. . :: .:: :.::. ..::..: . ::::. CCDS81 CAPKMQTAYGIKAQRSA-DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 LQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQ-PRLRTDVPGELLQKLRFG ... . . .: . ::::...::: ::.:: .:: .. .. :: . :: . CCDS81 IMMSILATLPTNMGGLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTS---- 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE1 SQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASA---PRAR :.. . . : .:. ... ..:.:. .::..::::. : :::.: .. : . CCDS81 SKVHLYRELTCDEVLQRIESLEEEIISKGI-KLVILDSVASVVRKEFDAQLQGNLKERNK 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 HLQSLGATLRELSSAFQSPVLCINQVTE----AMEEQGAAHGP---LGFWDER-----VS : ...:. :. :. ::. ::.: :. :. .: :.. . : CCDS81 FLAREASSLKYLAEEFSIPVILTNQITTHLSGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 290 300 310 320 330 340 pF1KE1 PALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTP ::: ::.... .::. . : :. : . . ..: : .: :::. ::. CCDS81 AALGNTWSHSVNTRLILQYLDSER-------RQILIAKSPLAPFTSFVYTIKEEGLVLQV 300 310 320 330 340 pF1KE1 GTQSH CCDS81 VRTVARVSPRSECWSAADSHPSPTFLIPDVVLRKTRNPRLLPSVSMCPPQMHSTVLSSAL 350 360 370 380 390 400 346 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:46:54 2016 done: Sat Nov 5 07:46:55 2016 Total Scan time: 2.850 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]