FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1050, 476 aa 1>>>pF1KE1050 476 - 476 aa - 476 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.5058+/-0.000426; mu= -7.6767+/- 0.026 mean_var=495.4815+/-101.104, 0's: 0 Z-trim(125.3): 253 B-trim: 1606 in 1/57 Lambda= 0.057618 statistics sampled from 48570 (48870) to 48570 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.837), E-opt: 0.2 (0.573), width: 16 Scan time: 11.720 The best scores are: opt bits E(85289) NP_003293 (OMIM: 602933) thyroid receptor-interact ( 476) 3499 305.0 2.9e-82 NP_005569 (OMIM: 600700) lipoma-preferred partner ( 612) 1296 122.0 4.6e-27 XP_016861867 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_005247503 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_016861868 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511129 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_016861869 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_005247510 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_005247507 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511130 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511133 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511135 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511122 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511136 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 NP_001161143 (OMIM: 600700) lipoma-preferred partn ( 612) 1296 122.0 4.6e-27 XP_016861866 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_005247508 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1296 122.0 4.6e-27 XP_011511125 (OMIM: 600700) PREDICTED: lipoma-pref ( 637) 1296 122.0 4.7e-27 XP_016861871 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 1289 121.3 5.6e-27 XP_011511138 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 1289 121.3 5.6e-27 NP_001161144 (OMIM: 600700) lipoma-preferred partn ( 465) 1272 119.9 1.5e-26 XP_011514871 (OMIM: 602002) PREDICTED: zyxin isofo ( 541) 1033 100.1 1.6e-20 NP_003452 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 1011 98.3 6e-20 NP_001010972 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 1011 98.3 6e-20 XP_016868076 (OMIM: 602002) PREDICTED: zyxin isofo ( 631) 1011 98.3 6.4e-20 NP_116265 (OMIM: 609066) LIM domain-containing pro ( 538) 812 81.7 5.5e-15 NP_001073905 (OMIM: 614790) Wilms tumor protein 1- ( 430) 797 80.4 1.1e-14 NP_055055 (OMIM: 604543) LIM domain-containing pro ( 676) 776 78.8 5.1e-14 XP_005245966 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 719 73.8 9.1e-13 XP_011539919 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 719 73.8 9.1e-13 NP_060026 (OMIM: 607747) filamin-binding LIM prote ( 373) 719 73.8 9.1e-13 XP_016857014 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 719 73.8 9.1e-13 XP_011524754 (OMIM: 614790) PREDICTED: Wilms tumor ( 472) 680 70.7 1e-11 XP_006723077 (OMIM: 614790) PREDICTED: Wilms tumor ( 384) 670 69.8 1.6e-11 NP_001019387 (OMIM: 607747) filamin-binding LIM pr ( 276) 666 69.3 1.6e-11 XP_011524755 (OMIM: 614790) PREDICTED: Wilms tumor ( 231) 548 59.4 1.3e-08 NP_932352 (OMIM: 609066) LIM domain-containing pro ( 121) 520 56.7 4.1e-08 XP_011539918 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_005245959 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_016857013 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_016857008 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_016857011 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_005245957 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_016857012 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 NP_001019386 (OMIM: 607747) filamin-binding LIM pr ( 374) 470 53.1 1.6e-06 XP_016857009 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_005245958 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_006710768 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_016857010 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 XP_005245960 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 470 53.1 1.6e-06 >>NP_003293 (OMIM: 602933) thyroid receptor-interacting (476 aa) initn: 3499 init1: 3499 opt: 3499 Z-score: 1597.8 bits: 305.0 E(85289): 2.9e-82 Smith-Waterman score: 3499; 100.0% identity (100.0% similar) in 476 aa overlap (1-476:1-476) 10 20 30 40 50 60 pF1KE1 MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRPDR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QAYEPPPPPAYRTGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QAYEPPPPPAYRTGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVKVAQPVRG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 CGPPRRGASQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 CGPPRRGASQASGPLPGPHFPLPGRGEVWGPGYRSQREPGPGAKEEAAGVSGPAGRGRGG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 EHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EHGPQVPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 HVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HVGCFVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 GCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVA 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 LDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC 430 440 450 460 470 >>NP_005569 (OMIM: 600700) lipoma-preferred partner isof (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : NP_005 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : NP_005 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : NP_005 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. NP_005 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. NP_005 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : NP_005 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: NP_005 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. NP_005 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: NP_005 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_016861867 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_016 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_016 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_016 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_016 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_016 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_016 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_016 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_016 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_016 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_005247503 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_005 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_005 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_005 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_005 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_005 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_005 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_005 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_005 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_005 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_016861868 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_016 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_016 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_016 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_016 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_016 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_016 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_016 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_016 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_016 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_011511129 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_011 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_011 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_011 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_011 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_011 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_011 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_011 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_011 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_011 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_016861869 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_016 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_016 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_016 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_016 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_016 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_016 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_016 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_016 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_016 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_005247510 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_005 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_005 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_005 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_005 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_005 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_005 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_005 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_005 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_005 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_005247507 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_005 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_005 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_005 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_005 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_005 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_005 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_005 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_005 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_005 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 >>XP_011511130 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1268 init1: 1032 opt: 1296 Z-score: 606.8 bits: 122.0 E(85289): 4.6e-27 Smith-Waterman score: 1361; 47.9% identity (62.9% similar) in 501 aa overlap (89-475:113-611) 60 70 80 90 100 110 pF1KE1 GGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLLSSTLAELNGGRGHASRRP : .::::::: :.: ::.:. . . : : XP_011 SISGNFPPPPPLDEEAFKVQGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRPP 90 100 110 120 130 140 120 130 140 150 pF1KE1 DRQ--AYEPPP----------------PP--AYRTGSLKPNPA---SPLPASPYGG---- . . . :: :: : . ..:::.:: .:.:..: : XP_011 QSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQ 150 160 170 180 190 200 160 170 180 pF1KE1 --PTPASYTTASTPAGPAFPVQVKVAQP---------------------------VRG-C :.::::::::: . :.: :::: ::: : : : XP_011 PQPVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQC 210 220 230 240 250 260 190 200 210 pF1KE1 GPP--RRGASQASGPLPGPHFPLPGRGEV------------WGPGY--RS---------- :: : : . : : :: . : :: : . :::: :. XP_011 PPPSTRGGMDYAYIPPPGLQ-PEPGYGYAPNQGRYYEGYYAAGPGYGGRNDSDPTYGQQG 270 280 290 300 310 320 220 230 240 pF1KE1 -----QREPG---PGA-KEEAAG---VSGPAGR------------------GRGGEHGPQ .:::: ::: ... : :.:: :..:. ::. XP_011 HPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPS 330 340 350 360 370 380 250 260 270 280 290 300 pF1KE1 -VPLSQPPEDELDRLTKKLVHDMNHPPSGEYFGQCGGCGEDVVGDGAGVVALDRVFHVGC : : :::::..::::...::..::. ::::.:. :::.:::.:.: .:.:.:::: : XP_011 SVAPSFRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDC 390 400 410 420 430 440 310 320 330 340 350 360 pF1KE1 FVCSTCRAQLRGQHFYAVERRAYCEGCYVATLEKCATCSQPILDRILRAMGKAYHPGCFT :.: : .:::: :::::..:::: ::. :::.: .::.::..::::: :::::: ::: XP_011 FTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIMERILRATGKAYHPHCFT 450 460 470 480 490 500 370 380 390 400 410 420 pF1KE1 CVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEPGQEETVRIVALDRS ::.:::.:::::::::: . ::::::::.::::::::: ::: ::::::::::::::. XP_011 CVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRD 510 520 530 540 550 560 430 440 450 460 470 pF1KE1 FHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRIQELSATVTTDC ::. ::.::.:: ::: ::. :::::::::::::.:.. ::. :.: ..:: XP_011 FHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRVLTAKASTDL 570 580 590 600 610 476 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:48:41 2016 done: Sat Nov 5 07:48:43 2016 Total Scan time: 11.720 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]