FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1052, 375 aa 1>>>pF1KE1052 375 - 375 aa - 375 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3005+/-0.000897; mu= 11.8779+/- 0.054 mean_var=91.7667+/-17.990, 0's: 0 Z-trim(106.7): 41 B-trim: 0 in 0/54 Lambda= 0.133885 statistics sampled from 9129 (9157) to 9129 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.281), width: 16 Scan time: 2.710 The best scores are: opt bits E(32554) CCDS6003.1 PDGFRL gene_id:5157|Hs108|chr8 ( 375) 2501 493.3 1.4e-139 CCDS53861.1 FLT1 gene_id:2321|Hs108|chr13 ( 541) 347 77.4 3.4e-14 CCDS73556.1 FLT1 gene_id:2321|Hs108|chr13 ( 687) 347 77.4 4.2e-14 CCDS53860.1 FLT1 gene_id:2321|Hs108|chr13 ( 733) 347 77.4 4.4e-14 CCDS9330.1 FLT1 gene_id:2321|Hs108|chr13 (1338) 347 77.6 7.3e-14 >>CCDS6003.1 PDGFRL gene_id:5157|Hs108|chr8 (375 aa) initn: 2501 init1: 2501 opt: 2501 Z-score: 2619.3 bits: 493.3 E(32554): 1.4e-139 Smith-Waterman score: 2501; 100.0% identity (100.0% similar) in 375 aa overlap (1-375:1-375) 10 20 30 40 50 60 pF1KE1 MKVWLLLGLLLVHEALEDVTGQHLPKNKRPKEPGENRIKPTNKKVKPKIPKMKDRDSANS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MKVWLLLGLLLVHEALEDVTGQHLPKNKRPKEPGENRIKPTNKKVKPKIPKMKDRDSANS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 APKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 APKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 QNERYGQLTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QNERYGQLTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFFTEKGELFVPSPSY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 FDVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FDVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYDMKRGFVYLQPHSEH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 QGVVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QGVVYCRAEAGGRSQISVKYQLLYVAVPSGPPSTTILASSNKVKSGDDISVLCTVLGEPD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 VEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVITVEDFETIDAGYYICTAQ 310 320 330 340 350 360 370 pF1KE1 NLQGQTTVATTVEFS ::::::::::::::: CCDS60 NLQGQTTVATTVEFS 370 >>CCDS53861.1 FLT1 gene_id:2321|Hs108|chr13 (541 aa) initn: 267 init1: 80 opt: 347 Z-score: 368.3 bits: 77.4 E(32554): 3.4e-14 Smith-Waterman score: 347; 26.0% identity (58.7% similar) in 300 aa overlap (86-372:43-326) 60 70 80 90 100 110 pF1KE1 DSANSAPKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIG-WSYPAYLDTFKD . ::::..:.:.: :: : ... .. CCDS53 ALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSK-ES 20 30 40 50 60 70 120 130 140 150 160 pF1KE1 SRLSVKQNE--RYGQ-----LTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFF :::. .. : :. ::: .. . :: .:: . . .: :... . :::. CCDS53 ERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSC--KYLAVPTSKKKETES-AIYIFI 80 90 100 110 120 170 180 190 200 210 220 pF1KE1 TEKGELFVPSPSYF-DVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYD .. :. :: : . ...... :. :.::::: . ::: ..:: . .: :..: CCDS53 SDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTL-KKFPLDTLIPDGKRIIWD 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE1 MKRGFVYLQPHSEHQGVVYCRAEAGGR----SQISVKYQLLYVAVPSGPPSTTILASSNK ..::. . .. :.. :.: ..:. . .. . . : . : . : CCDS53 SRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV------K 190 200 210 220 230 240 290 300 310 320 330 340 pF1KE1 VKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVI . : . . ::. ...:..:: .: .:..: .... : : .. .:.. : ::. CCDS53 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKR-ASVR---RRIDQSNSHAN-IFYSVL 250 260 270 280 290 350 360 370 pF1KE1 TVEDFETIDAGYYICTAQNLQGQTTVATTVEFS :.. ... : : : : ... . .: :.: CCDS53 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 300 310 320 330 340 350 >>CCDS73556.1 FLT1 gene_id:2321|Hs108|chr13 (687 aa) initn: 267 init1: 80 opt: 347 Z-score: 366.8 bits: 77.4 E(32554): 4.2e-14 Smith-Waterman score: 347; 26.0% identity (58.7% similar) in 300 aa overlap (86-372:43-326) 60 70 80 90 100 110 pF1KE1 DSANSAPKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIG-WSYPAYLDTFKD . ::::..:.:.: :: : ... .. CCDS73 ALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSK-ES 20 30 40 50 60 70 120 130 140 150 160 pF1KE1 SRLSVKQNE--RYGQ-----LTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFF :::. .. : :. ::: .. . :: .:: . . .: :... . :::. CCDS73 ERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSC--KYLAVPTSKKKETES-AIYIFI 80 90 100 110 120 170 180 190 200 210 220 pF1KE1 TEKGELFVPSPSYF-DVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYD .. :. :: : . ...... :. :.::::: . ::: ..:: . .: :..: CCDS73 SDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTL-KKFPLDTLIPDGKRIIWD 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE1 MKRGFVYLQPHSEHQGVVYCRAEAGGR----SQISVKYQLLYVAVPSGPPSTTILASSNK ..::. . .. :.. :.: ..:. . .. . . : . : . : CCDS73 SRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV------K 190 200 210 220 230 240 290 300 310 320 330 340 pF1KE1 VKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVI . : . . ::. ...:..:: .: .:..: .... : : .. .:.. : ::. CCDS73 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKR-ASVR---RRIDQSNSHAN-IFYSVL 250 260 270 280 290 350 360 370 pF1KE1 TVEDFETIDAGYYICTAQNLQGQTTVATTVEFS :.. ... : : : : ... . .: :.: CCDS73 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 300 310 320 330 340 350 >>CCDS53860.1 FLT1 gene_id:2321|Hs108|chr13 (733 aa) initn: 267 init1: 80 opt: 347 Z-score: 366.3 bits: 77.4 E(32554): 4.4e-14 Smith-Waterman score: 347; 26.0% identity (58.7% similar) in 300 aa overlap (86-372:43-326) 60 70 80 90 100 110 pF1KE1 DSANSAPKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIG-WSYPAYLDTFKD . ::::..:.:.: :: : ... .. CCDS53 ALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSK-ES 20 30 40 50 60 70 120 130 140 150 160 pF1KE1 SRLSVKQNE--RYGQ-----LTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFF :::. .. : :. ::: .. . :: .:: . . .: :... . :::. CCDS53 ERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSC--KYLAVPTSKKKETES-AIYIFI 80 90 100 110 120 170 180 190 200 210 220 pF1KE1 TEKGELFVPSPSYF-DVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYD .. :. :: : . ...... :. :.::::: . ::: ..:: . .: :..: CCDS53 SDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTL-KKFPLDTLIPDGKRIIWD 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE1 MKRGFVYLQPHSEHQGVVYCRAEAGGR----SQISVKYQLLYVAVPSGPPSTTILASSNK ..::. . .. :.. :.: ..:. . .. . . : . : . : CCDS53 SRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV------K 190 200 210 220 230 240 290 300 310 320 330 340 pF1KE1 VKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVI . : . . ::. ...:..:: .: .:..: .... : : .. .:.. : ::. CCDS53 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKR-ASVR---RRIDQSNSHAN-IFYSVL 250 260 270 280 290 350 360 370 pF1KE1 TVEDFETIDAGYYICTAQNLQGQTTVATTVEFS :.. ... : : : : ... . .: :.: CCDS53 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 300 310 320 330 340 350 >>CCDS9330.1 FLT1 gene_id:2321|Hs108|chr13 (1338 aa) initn: 267 init1: 80 opt: 347 Z-score: 362.4 bits: 77.6 E(32554): 7.3e-14 Smith-Waterman score: 347; 26.0% identity (58.7% similar) in 300 aa overlap (86-372:43-326) 60 70 80 90 100 110 pF1KE1 DSANSAPKTQSIMMQVLDKGRFQKPAATLSLLAGQTVELRCKGSRIG-WSYPAYLDTFKD . ::::..:.:.: :: : ... .. CCDS93 ALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSK-ES 20 30 40 50 60 70 120 130 140 150 160 pF1KE1 SRLSVKQNE--RYGQ-----LTLVNSTSADTGEFSCWVQLCSGYICRKDEAKTGSTYIFF :::. .. : :. ::: .. . :: .:: . . .: :... . :::. CCDS93 ERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSC--KYLAVPTSKKKETES-AIYIFI 80 90 100 110 120 170 180 190 200 210 220 pF1KE1 TEKGELFVPSPSYF-DVVYLNPDRQAVVPCRVTVLSAKVTLHREFPAKEIPANGTDIVYD .. :. :: : . ...... :. :.::::: . ::: ..:: . .: :..: CCDS93 SDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTL-KKFPLDTLIPDGKRIIWD 130 140 150 160 170 180 230 240 250 260 270 280 pF1KE1 MKRGFVYLQPHSEHQGVVYCRAEAGGR----SQISVKYQLLYVAVPSGPPSTTILASSNK ..::. . .. :.. :.: ..:. . .. . . : . : . : CCDS93 SRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPV------K 190 200 210 220 230 240 290 300 310 320 330 340 pF1KE1 VKSGDDISVLCTVLGEPDVEVEFTWIFPGQKDERPVTIQDTWRLIHRGLGHTTRISQSVI . : . . ::. ...:..:: .: .:..: .... : : .. .:.. : ::. CCDS93 LLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKR-ASVR---RRIDQSNSHAN-IFYSVL 250 260 270 280 290 350 360 370 pF1KE1 TVEDFETIDAGYYICTAQNLQGQTTVATTVEFS :.. ... : : : : ... . .: :.: CCDS93 TIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLS 300 310 320 330 340 350 375 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:49:47 2016 done: Sat Nov 5 07:49:48 2016 Total Scan time: 2.710 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]