FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1067, 506 aa
  1>>>pF1KE1067 506 - 506 aa - 506 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5546+/-0.000324; mu= 8.5710+/- 0.020
 mean_var=146.9859+/-29.415, 0's: 0 Z-trim(120.1): 87  B-trim: 35 in 1/56
 Lambda= 0.105788
 statistics sampled from 34818 (34924) to 34818 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.409), width:  16
 Scan time:  9.350

The best scores are:                                      opt bits E(85289)
NP_055512 (OMIM: 605551) carboxyl-terminal PDZ lig ( 506) 3331 520.0 6.5e-147
NP_001158229 (OMIM: 605551) carboxyl-terminal PDZ  ( 501) 3284 512.8 9.3e-145
NP_001119532 (OMIM: 605551) carboxyl-terminal PDZ  ( 211) 1282 207.0 4.4e-53


>>NP_055512 (OMIM: 605551) carboxyl-terminal PDZ ligand   (506 aa)
 initn: 3331 init1: 3331 opt: 3331  Z-score: 2758.6  bits: 520.0 E(85289): 6.5e-147
Smith-Waterman score: 3331; 100.0% identity (100.0% similar) in 506 aa overlap (1-506:1-506)

               10        20        30        40        50        60
pF1KE1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
              430       440       450       460       470       480

              490       500      
pF1KE1 QEELPRLLNVLQRQELGDGLDDEIAV
       ::::::::::::::::::::::::::
NP_055 QEELPRLLNVLQRQELGDGLDDEIAV
              490       500      

>>NP_001158229 (OMIM: 605551) carboxyl-terminal PDZ liga  (501 aa)
 initn: 2718 init1: 2718 opt: 3284  Z-score: 2719.9  bits: 512.8 E(85289): 9.3e-145
Smith-Waterman score: 3284; 99.0% identity (99.0% similar) in 506 aa overlap (1-506:1-501)

               10        20        30        40        50        60
pF1KE1 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVS
       ::::::::::::::::::::::::::::::     :::::::::::::::::::::::::
NP_001 EFKAKNIKKKKVSIMVSVDGVKVILKKKKK-----KKEWTWDESKMLVMQDPIYRIFYVS
               70        80        90            100       110     

              130       140       150       160       170       180
pF1KE1 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNA
         120       130       140       150       160       170     

              190       200       210       220       230       240
pF1KE1 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDL
         180       190       200       210       220       230     

              250       260       270       280       290       300
pF1KE1 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLL
         240       250       260       270       280       290     

              310       320       330       340       350       360
pF1KE1 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELE
         300       310       320       330       340       350     

              370       380       390       400       410       420
pF1KE1 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLG
         360       370       380       390       400       410     

              430       440       450       460       470       480
pF1KE1 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWS
         420       430       440       450       460       470     

              490       500      
pF1KE1 QEELPRLLNVLQRQELGDGLDDEIAV
       ::::::::::::::::::::::::::
NP_001 QEELPRLLNVLQRQELGDGLDDEIAV
         480       490       500 

>>NP_001119532 (OMIM: 605551) carboxyl-terminal PDZ liga  (211 aa)
 initn: 1282 init1: 1282 opt: 1282  Z-score: 1074.0  bits: 207.0 E(85289): 4.4e-53
Smith-Waterman score: 1282; 100.0% identity (100.0% similar) in 194 aa overlap (313-506:18-211)

            290       300       310       320       330       340  
pF1KE1 TETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQN
                                     ::::::::::::::::::::::::::::::
NP_001              MSLSSLCPVFSAAASSLQVHLLKDQLAAEAAARLEAQARVHQLLLQN
                            10        20        30        40       

            350       360       370       380       390       400  
pF1KE1 KDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSP
        50        60        70        80        90       100       

            410       420       430       440       450       460  
pF1KE1 PLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGI
       110       120       130       140       150       160       

            470       480       490       500      
pF1KE1 ASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV
       170       180       190       200       210 




506 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:31:27 2016 done: Sat Nov  5 19:31:28 2016
 Total Scan time:  9.350 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]