FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1068, 577 aa 1>>>pF1KE1068 577 - 577 aa - 577 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.4039+/-0.000444; mu= 0.8804+/- 0.028 mean_var=243.8104+/-50.226, 0's: 0 Z-trim(118.9): 18 B-trim: 396 in 1/53 Lambda= 0.082139 statistics sampled from 32239 (32257) to 32239 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.378), width: 16 Scan time: 12.000 The best scores are: opt bits E(85289) NP_065827 (OMIM: 616480) protein hinderin isoform ( 577) 3829 467.1 6.8e-131 XP_005258374 (OMIM: 616480) PREDICTED: protein hin ( 573) 3688 450.4 7.2e-126 XP_016881367 (OMIM: 616480) PREDICTED: protein hin ( 469) 3137 385.1 2.8e-106 XP_011524402 (OMIM: 616480) PREDICTED: protein hin ( 456) 2683 331.3 4.3e-90 XP_005258372 (OMIM: 616480) PREDICTED: protein hin ( 613) 2683 331.3 5.4e-90 XP_016881365 (OMIM: 616480) PREDICTED: protein hin ( 609) 2542 314.6 5.8e-85 XP_016881366 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79 XP_011524401 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79 XP_005258375 (OMIM: 616480) PREDICTED: protein hin ( 568) 2383 295.8 2.6e-79 NP_001309256 (OMIM: 616480) protein hinderin isofo ( 505) 1991 249.3 2.3e-65 XP_016881370 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51 XP_016881369 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51 XP_016881368 (OMIM: 616480) PREDICTED: protein hin ( 436) 1580 200.5 9.2e-51 >>NP_065827 (OMIM: 616480) protein hinderin isoform 1 [H (577 aa) initn: 3829 init1: 3829 opt: 3829 Z-score: 2470.9 bits: 467.1 E(85289): 6.8e-131 Smith-Waterman score: 3829; 99.7% identity (100.0% similar) in 577 aa overlap (1-577:1-577) 10 20 30 40 50 60 pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE :.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_065 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN 490 500 510 520 530 540 550 560 570 pF1KE1 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI ::::::::::::::::::::::::::::::::::::: NP_065 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 550 560 570 >>XP_005258374 (OMIM: 616480) PREDICTED: protein hinderi (573 aa) initn: 3688 init1: 3688 opt: 3688 Z-score: 2380.7 bits: 450.4 E(85289): 7.2e-126 Smith-Waterman score: 3688; 99.6% identity (100.0% similar) in 557 aa overlap (21-577:17-573) 10 20 30 40 50 60 pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT :::::::::::::::::::::::::::::::::::::::: XP_005 MPDNIIVFSFMFSCVVSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE :.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE1 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN 480 490 500 510 520 530 550 560 570 pF1KE1 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI ::::::::::::::::::::::::::::::::::::: XP_005 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 540 550 560 570 >>XP_016881367 (OMIM: 616480) PREDICTED: protein hinderi (469 aa) initn: 3137 init1: 3137 opt: 3137 Z-score: 2029.0 bits: 385.1 E(85289): 2.8e-106 Smith-Waterman score: 3137; 99.6% identity (99.8% similar) in 469 aa overlap (109-577:1-469) 80 90 100 110 120 130 pF1KE1 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE . :::::::::::::::::::::::::::: XP_016 MNRVSEEKEVTEERLKAEQESFEKKIRQLE 10 20 30 140 150 160 170 180 190 pF1KE1 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE1 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE1 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE1 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE1 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGWLLGTSSSIKKHQDPPNSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGWLLGTSSSIKKHQDPPNSG 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE1 ENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTA 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE1 SPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGM 400 410 420 430 440 450 560 570 pF1KE1 HRTPEELEENQILEDIFFI ::::::::::::::::::: XP_016 HRTPEELEENQILEDIFFI 460 >>XP_011524402 (OMIM: 616480) PREDICTED: protein hinderi (456 aa) initn: 2683 init1: 2683 opt: 2683 Z-score: 1738.4 bits: 331.3 E(85289): 4.3e-90 Smith-Waterman score: 2683; 99.5% identity (100.0% similar) in 410 aa overlap (1-410:1-410) 10 20 30 40 50 60 pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE :.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_011 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD XP_011 RELVAEKQLTKPQELKLDMNGSDSGPSSFIVVLSVY 430 440 450 >>XP_005258372 (OMIM: 616480) PREDICTED: protein hinderi (613 aa) initn: 3802 init1: 2683 opt: 2683 Z-score: 1736.6 bits: 331.3 E(85289): 5.4e-90 Smith-Waterman score: 3707; 93.6% identity (93.9% similar) in 609 aa overlap (1-573:1-609) 10 20 30 40 50 60 pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE :.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_005 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 310 320 330 340 350 360 370 380 390 400 410 pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS 370 380 390 400 410 420 420 430 440 pF1KE1 --------------------------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER ::::::::::::::::::::::::::::::::: XP_005 RELVAEKQLTKPQELKLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER 430 440 450 460 470 480 450 460 470 480 490 500 pF1KE1 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH 490 500 510 520 530 540 510 520 530 540 550 560 pF1KE1 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE 550 560 570 580 590 600 570 pF1KE1 LEENQILEDIFFI ::::::::: XP_005 LEENQILEDIFFI 610 >>XP_016881365 (OMIM: 616480) PREDICTED: protein hinderi (609 aa) initn: 3661 init1: 2542 opt: 2542 Z-score: 1646.4 bits: 314.6 E(85289): 5.8e-85 Smith-Waterman score: 3566; 93.4% identity (93.7% similar) in 589 aa overlap (21-573:17-605) 10 20 30 40 50 60 pF1KE1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT :::::::::::::::::::::::::::::::::::::::: XP_016 MPDNIIVFSFMFSCVVSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 DVSISMESLKGTGDSADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE :.:::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: XP_016 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE1 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 300 310 320 330 340 350 370 380 390 400 410 pF1KE1 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN---------- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKS 360 370 380 390 400 410 420 430 440 pF1KE1 --------------------------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER ::::::::::::::::::::::::::::::::: XP_016 RELVAEKQLTKPQELKLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKER 420 430 440 450 460 470 450 460 470 480 490 500 pF1KE1 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQH 480 490 500 510 520 530 510 520 530 540 550 560 pF1KE1 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEE 540 550 560 570 580 590 570 pF1KE1 LEENQILEDIFFI ::::::::: XP_016 LEENQILEDIFFI 600 >>XP_016881366 (OMIM: 616480) PREDICTED: protein hinderi (568 aa) initn: 3502 init1: 2383 opt: 2383 Z-score: 1545.0 bits: 295.8 E(85289): 2.6e-79 Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564) 20 30 40 50 60 70 pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS ::::::::::::::::.::::::::::::: XP_016 MSPKADVKLKTSRVTDASISMESLKGTGDS 10 20 30 80 90 100 110 120 130 pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM 280 290 300 310 320 330 380 390 400 410 pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN------------------------- ::::::::::::::::::::::::::::::::::: XP_016 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL 340 350 360 370 380 390 420 430 440 450 pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW 400 410 420 430 440 450 460 470 480 490 500 510 pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS 460 470 480 490 500 510 520 530 540 550 560 570 pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 520 530 540 550 560 >>XP_011524401 (OMIM: 616480) PREDICTED: protein hinderi (568 aa) initn: 3502 init1: 2383 opt: 2383 Z-score: 1545.0 bits: 295.8 E(85289): 2.6e-79 Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564) 20 30 40 50 60 70 pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS ::::::::::::::::.::::::::::::: XP_011 MSPKADVKLKTSRVTDASISMESLKGTGDS 10 20 30 80 90 100 110 120 130 pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM 280 290 300 310 320 330 380 390 400 410 pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN------------------------- ::::::::::::::::::::::::::::::::::: XP_011 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL 340 350 360 370 380 390 420 430 440 450 pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW 400 410 420 430 440 450 460 470 480 490 500 510 pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS 460 470 480 490 500 510 520 530 540 550 560 570 pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 520 530 540 550 560 >>XP_005258375 (OMIM: 616480) PREDICTED: protein hinderi (568 aa) initn: 3502 init1: 2383 opt: 2383 Z-score: 1545.0 bits: 295.8 E(85289): 2.6e-79 Smith-Waterman score: 3407; 93.1% identity (93.4% similar) in 564 aa overlap (46-573:1-564) 20 30 40 50 60 70 pF1KE1 WSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDVSISMESLKGTGDS ::::::::::::::::.::::::::::::: XP_005 MSPKADVKLKTSRVTDASISMESLKGTGDS 10 20 30 80 90 100 110 120 130 pF1KE1 ADEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE1 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE1 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE1 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM 280 290 300 310 320 330 380 390 400 410 pF1KE1 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYN------------------------- ::::::::::::::::::::::::::::::::::: XP_005 ELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQEL 340 350 360 370 380 390 420 430 440 450 pF1KE1 -----------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLDMNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQW 400 410 420 430 440 450 460 470 480 490 500 510 pF1KE1 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQS 460 470 480 490 500 510 520 530 540 550 560 570 pF1KE1 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSPNSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 520 530 540 550 560 >>NP_001309256 (OMIM: 616480) protein hinderin isoform 2 (505 aa) initn: 3110 init1: 1991 opt: 1991 Z-score: 1294.6 bits: 249.3 E(85289): 2.3e-65 Smith-Waterman score: 3015; 92.2% identity (92.4% similar) in 501 aa overlap (109-573:1-501) 80 90 100 110 120 130 pF1KE1 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE . :::::::::::::::::::::::::::: NP_001 MNRVSEEKEVTEERLKAEQESFEKKIRQLE 10 20 30 140 150 160 170 180 190 pF1KE1 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE1 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDD 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE1 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDS 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE1 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE 220 230 240 250 260 270 380 390 400 410 pF1KE1 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYN---------------------------- :::::::::::::::::::::::::::::::: NP_001 IEKERLQHLLAQQETKLLLKQQQLHQSRLDYNWLKAQALFKSRELVAEKQLTKPQELKLD 280 290 300 310 320 330 420 430 440 450 460 pF1KE1 --------CLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQ ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNGSDSGPSLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQ 340 350 360 370 380 390 470 480 490 500 510 520 pF1KE1 KKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSP 400 410 420 430 440 450 530 540 550 560 570 pF1KE1 NSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSAPKPQRYPSREAGAWNHGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 460 470 480 490 500 577 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:30:49 2016 done: Sat Nov 5 19:30:51 2016 Total Scan time: 12.000 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]