Result of FASTA (omim) for
pF1KE1069
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1069, 177 aa
1>>>pF1KE1069 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1170+/-0.000296; mu= 8.9682+/- 0.019
mean_var=75.7194+/-15.020, 0's: 0 Z-trim(118.7): 30 B-trim: 1189 in 1/52
Lambda= 0.147391
statistics sampled from 31863 (31893) to 31863 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.374), width: 16
Scan time: 5.410
The best scores are: opt bits E(85289)
NP_758955 (OMIM: 612211) tumor suppressor candidat ( 177) 1130 248.8 3.3e-66
XP_016878377 (OMIM: 128200,614386) PREDICTED: prol ( 340) 339 80.7 2.6e-15
NP_660282 (OMIM: 128200,614386) proline-rich trans ( 340) 339 80.7 2.6e-15
XP_016878378 (OMIM: 128200,614386) PREDICTED: prol ( 340) 331 79.0 8.4e-15
XP_016878376 (OMIM: 128200,614386) PREDICTED: prol ( 346) 331 79.0 8.5e-15
XP_011544018 (OMIM: 128200,614386) PREDICTED: prol ( 394) 331 79.0 9.5e-15
XP_011544017 (OMIM: 128200,614386) PREDICTED: prol ( 394) 331 79.0 9.5e-15
NP_001243371 (OMIM: 128200,614386) proline-rich tr ( 394) 331 79.0 9.5e-15
NP_001243372 (OMIM: 128200,614386) proline-rich tr ( 299) 165 43.7 0.00031
>>NP_758955 (OMIM: 612211) tumor suppressor candidate 5 (177 aa)
initn: 1130 init1: 1130 opt: 1130 Z-score: 1309.6 bits: 248.8 E(85289): 3.3e-66
Smith-Waterman score: 1130; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)
10 20 30 40 50 60
pF1KE1 MAHPVQSEFPSAQEPGSAAFLDLPEMEILLTKAENKDDKTLNLSKTLSGPLDLEQNSQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 MAHPVQSEFPSAQEPGSAAFLDLPEMEILLTKAENKDDKTLNLSKTLSGPLDLEQNSQGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEAPRDYLILAVVACFCPVWPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 PFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEAPRDYLILAVVACFCPVWPLN
70 80 90 100 110 120
130 140 150 160 170
pF1KE1 LIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGIVIIMVAVTVNFTVQKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_758 LIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGIVIIMVAVTVNFTVQKK
130 140 150 160 170
>>XP_016878377 (OMIM: 128200,614386) PREDICTED: proline- (340 aa)
initn: 350 init1: 325 opt: 339 Z-score: 396.0 bits: 80.7 E(85289): 2.6e-15
Smith-Waterman score: 339; 45.7% identity (78.1% similar) in 105 aa overlap (75-176:236-340)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:. : :
XP_016 LIIIASCVINLGVYK
330 340
>>NP_660282 (OMIM: 128200,614386) proline-rich transmemb (340 aa)
initn: 350 init1: 325 opt: 339 Z-score: 396.0 bits: 80.7 E(85289): 2.6e-15
Smith-Waterman score: 339; 45.7% identity (78.1% similar) in 105 aa overlap (75-176:236-340)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
NP_660 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
NP_660 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:. : :
NP_660 LIIIASCVINLGVYK
330 340
>>XP_016878378 (OMIM: 128200,614386) PREDICTED: proline- (340 aa)
initn: 342 init1: 317 opt: 331 Z-score: 386.8 bits: 79.0 E(85289): 8.4e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:.
XP_016 LIIIASCVINLGDAA
330 340
>>XP_016878376 (OMIM: 128200,614386) PREDICTED: proline- (346 aa)
initn: 342 init1: 317 opt: 331 Z-score: 386.7 bits: 79.0 E(85289): 8.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
XP_016 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
XP_016 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:.
XP_016 LIIIASCVINLGGCCMSLKHQ
330 340
>>XP_011544018 (OMIM: 128200,614386) PREDICTED: proline- (394 aa)
initn: 342 init1: 317 opt: 331 Z-score: 385.7 bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
XP_011 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
XP_011 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:.
XP_011 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
330 340 350 360 370 380
>>XP_011544017 (OMIM: 128200,614386) PREDICTED: proline- (394 aa)
initn: 342 init1: 317 opt: 331 Z-score: 385.7 bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
XP_011 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
XP_011 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:.
XP_011 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
330 340 350 360 370 380
>>NP_001243371 (OMIM: 128200,614386) proline-rich transm (394 aa)
initn: 342 init1: 317 opt: 331 Z-score: 385.7 bits: 79.0 E(85289): 9.5e-15
Smith-Waterman score: 331; 45.5% identity (79.2% similar) in 101 aa overlap (75-172:236-336)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
NP_001 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:::.:.:::.::::.::::.:.::::. .. :.
NP_001 RDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGV
270 280 290 300 310 320
170
pF1KE1 VIIMVAVTVNFTVQKK
.::... ..:.
NP_001 LIIIASCVINLGGEWGLGTGRGGMEGLARAALLTPAPALSCLSSLPLLCLSLSPPPPVCP
330 340 350 360 370 380
>>NP_001243372 (OMIM: 128200,614386) proline-rich transm (299 aa)
initn: 176 init1: 151 opt: 165 Z-score: 196.9 bits: 43.7 E(85289): 0.00031
Smith-Waterman score: 165; 39.7% identity (69.0% similar) in 58 aa overlap (75-129:236-293)
50 60 70 80 90 100
pF1KE1 KTLSGPLDLEQNSQGLPFKAISEGHLEAPLPRSPSRASSRRASSIATTSYAQDQEA---P
: :: . ::. :: . .. :. :
NP_001 KKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKP
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE1 RDYLILAVVACFCPVWPLNLIPLIISIMSRSSMQQGNVDGARRLGRLARLLSITLIIMGI
:::.:::...::::.::.:.. . ..:
NP_001 RDYIILAILSCFCPMWPVNIVAFAYAVMVSPMGP
270 280 290
177 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:42:15 2016 done: Fri Nov 4 04:42:16 2016
Total Scan time: 5.410 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]