FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1073, 811 aa 1>>>pF1KE1073 811 - 811 aa - 811 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.2556+/-0.000729; mu= -21.0986+/- 0.044 mean_var=659.1030+/-136.845, 0's: 0 Z-trim(116.2): 308 B-trim: 328 in 1/54 Lambda= 0.049957 statistics sampled from 26808 (27111) to 26808 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.318), width: 16 Scan time: 14.760 The best scores are: opt bits E(85289) NP_009090 (OMIM: 602701) sarcolemmal membrane-asso ( 811) 5173 389.3 3.7e-107 XP_005265523 (OMIM: 602701) PREDICTED: sarcolemmal ( 811) 5173 389.3 3.7e-107 XP_005265522 (OMIM: 602701) PREDICTED: sarcolemmal ( 813) 5159 388.3 7.4e-107 XP_016862642 (OMIM: 602701) PREDICTED: sarcolemmal ( 807) 5011 377.6 1.2e-103 XP_005265524 (OMIM: 602701) PREDICTED: sarcolemmal ( 809) 4997 376.6 2.4e-103 XP_016862641 (OMIM: 602701) PREDICTED: sarcolemmal ( 808) 4975 375.0 7.2e-103 XP_011532405 (OMIM: 602701) PREDICTED: sarcolemmal ( 809) 4974 374.9 7.6e-103 XP_016862640 (OMIM: 602701) PREDICTED: sarcolemmal ( 810) 4961 374.0 1.5e-102 XP_016862643 (OMIM: 602701) PREDICTED: sarcolemmal ( 804) 4813 363.3 2.3e-99 XP_016862644 (OMIM: 602701) PREDICTED: sarcolemmal ( 804) 4341 329.3 4.1e-89 XP_005265525 (OMIM: 602701) PREDICTED: sarcolemmal ( 806) 4304 326.7 2.6e-88 XP_016862646 (OMIM: 602701) PREDICTED: sarcolemmal ( 801) 4143 315.0 8e-85 XP_016862645 (OMIM: 602701) PREDICTED: sarcolemmal ( 803) 4106 312.4 5.1e-84 XP_016862653 (OMIM: 602701) PREDICTED: sarcolemmal ( 767) 3094 239.4 4.5e-62 XP_006713389 (OMIM: 602701) PREDICTED: sarcolemmal ( 770) 3094 239.4 4.5e-62 XP_011532406 (OMIM: 602701) PREDICTED: sarcolemmal ( 772) 3080 238.4 9.1e-62 XP_016862654 (OMIM: 602701) PREDICTED: sarcolemmal ( 763) 2961 229.8 3.4e-59 XP_016862655 (OMIM: 602701) PREDICTED: sarcolemmal ( 763) 2938 228.2 1.1e-58 XP_016862636 (OMIM: 602701) PREDICTED: sarcolemmal ( 828) 2816 219.4 5.1e-56 XP_005265517 (OMIM: 602701) PREDICTED: sarcolemmal ( 830) 2816 219.4 5.1e-56 XP_005265518 (OMIM: 602701) PREDICTED: sarcolemmal ( 828) 2815 219.3 5.3e-56 NP_001291349 (OMIM: 602701) sarcolemmal membrane-a ( 828) 2815 219.3 5.3e-56 XP_005265516 (OMIM: 602701) PREDICTED: sarcolemmal ( 830) 2815 219.3 5.4e-56 XP_005265514 (OMIM: 602701) PREDICTED: sarcolemmal ( 845) 2790 217.6 1.9e-55 XP_005265513 (OMIM: 602701) PREDICTED: sarcolemmal ( 847) 2790 217.6 1.9e-55 XP_016862652 (OMIM: 602701) PREDICTED: sarcolemmal ( 784) 2664 208.4 9.7e-53 XP_016862650 (OMIM: 602701) PREDICTED: sarcolemmal ( 787) 2664 208.4 9.7e-53 XP_005265519 (OMIM: 602701) PREDICTED: sarcolemmal ( 826) 2662 208.3 1.1e-52 NP_001291350 (OMIM: 602701) sarcolemmal membrane-a ( 790) 2651 207.5 1.9e-52 XP_005265528 (OMIM: 602701) PREDICTED: sarcolemmal ( 790) 2651 207.5 1.9e-52 XP_005265527 (OMIM: 602701) PREDICTED: sarcolemmal ( 792) 2651 207.5 1.9e-52 XP_016862649 (OMIM: 602701) PREDICTED: sarcolemmal ( 787) 2634 206.3 4.4e-52 XP_016862639 (OMIM: 602701) PREDICTED: sarcolemmal ( 825) 2618 205.1 1e-51 XP_016862638 (OMIM: 602701) PREDICTED: sarcolemmal ( 825) 2617 205.1 1.1e-51 XP_016862637 (OMIM: 602701) PREDICTED: sarcolemmal ( 827) 2617 205.1 1.1e-51 XP_016862635 (OMIM: 602701) PREDICTED: sarcolemmal ( 842) 2592 203.3 3.7e-51 XP_005265515 (OMIM: 602701) PREDICTED: sarcolemmal ( 844) 2592 203.3 3.7e-51 XP_005265521 (OMIM: 602701) PREDICTED: sarcolemmal ( 821) 2590 203.1 4e-51 XP_016862657 (OMIM: 602701) PREDICTED: sarcolemmal ( 746) 2524 198.3 1e-49 XP_016862658 (OMIM: 602701) PREDICTED: sarcolemmal ( 585) 2451 193.0 3.3e-48 XP_016862647 (OMIM: 602701) PREDICTED: sarcolemmal ( 789) 2453 193.2 3.7e-48 NP_001291351 (OMIM: 602701) sarcolemmal membrane-a ( 362) 2273 179.9 1.7e-44 XP_011532408 (OMIM: 602701) PREDICTED: sarcolemmal ( 362) 2273 179.9 1.7e-44 XP_016862659 (OMIM: 602701) PREDICTED: sarcolemmal ( 359) 2075 165.7 3.3e-40 NP_001298107 (OMIM: 602701) sarcolemmal membrane-a ( 359) 2075 165.7 3.3e-40 XP_011532407 (OMIM: 602701) PREDICTED: sarcolemmal ( 751) 1979 159.1 6.9e-38 XP_016862648 (OMIM: 602701) PREDICTED: sarcolemmal ( 789) 1968 158.3 1.2e-37 XP_005265529 (OMIM: 602701) PREDICTED: sarcolemmal ( 768) 1946 156.7 3.6e-37 NP_001291352 (OMIM: 602701) sarcolemmal membrane-a ( 296) 1777 144.1 8.5e-34 XP_016862656 (OMIM: 602701) PREDICTED: sarcolemmal ( 748) 1781 144.8 1.4e-33 >>NP_009090 (OMIM: 602701) sarcolemmal membrane-associat (811 aa) initn: 5173 init1: 5173 opt: 5173 Z-score: 2044.9 bits: 389.3 E(85289): 3.7e-107 Smith-Waterman score: 5173; 100.0% identity (100.0% similar) in 811 aa overlap (1-811:1-811) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE1 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE1 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE1 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN 730 740 750 760 770 780 790 800 810 pF1KE1 NKPWPWMPMLAALVAVTAIVLYVPGLARASP ::::::::::::::::::::::::::::::: NP_009 NKPWPWMPMLAALVAVTAIVLYVPGLARASP 790 800 810 >>XP_005265523 (OMIM: 602701) PREDICTED: sarcolemmal mem (811 aa) initn: 5173 init1: 5173 opt: 5173 Z-score: 2044.9 bits: 389.3 E(85289): 3.7e-107 Smith-Waterman score: 5173; 100.0% identity (100.0% similar) in 811 aa overlap (1-811:1-811) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE1 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE1 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE1 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN 730 740 750 760 770 780 790 800 810 pF1KE1 NKPWPWMPMLAALVAVTAIVLYVPGLARASP ::::::::::::::::::::::::::::::: XP_005 NKPWPWMPMLAALVAVTAIVLYVPGLARASP 790 800 810 >>XP_005265522 (OMIM: 602701) PREDICTED: sarcolemmal mem (813 aa) initn: 4382 init1: 4382 opt: 5159 Z-score: 2039.5 bits: 388.3 E(85289): 7.4e-107 Smith-Waterman score: 5159; 99.8% identity (99.8% similar) in 813 aa overlap (1-811:1-813) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK--VTH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_005 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKGTVTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE1 KIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE1 KENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE1 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE1 HIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAE 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE1 LERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE1 LKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSAD 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE1 LKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREK 730 740 750 760 770 780 780 790 800 810 pF1KE1 GNNKPWPWMPMLAALVAVTAIVLYVPGLARASP ::::::::::::::::::::::::::::::::: XP_005 GNNKPWPWMPMLAALVAVTAIVLYVPGLARASP 790 800 810 >>XP_016862642 (OMIM: 602701) PREDICTED: sarcolemmal mem (807 aa) initn: 5003 init1: 2571 opt: 5011 Z-score: 1981.8 bits: 377.6 E(85289): 1.2e-103 Smith-Waterman score: 5011; 97.5% identity (98.2% similar) in 814 aa overlap (1-811:1-807) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 390 400 410 pF1KE1 EALQADNDFTNERLTALQ---EHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKL :::::::::::::::::: ::: :. .:. . .::::::::::::::::: XP_016 EALQADNDFTNERLTALQVRLEHLQEKTLKECSSL-------EKLIVEGHLTKAVEETKL 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 SKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIE 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE1 AKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE1 LHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE1 ELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECH 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE1 SLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSA 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE1 DLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLRE 720 730 740 750 760 770 780 790 800 810 pF1KE1 KGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP :::::::::::::::::::::::::::::::::: XP_016 KGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP 780 790 800 >>XP_005265524 (OMIM: 602701) PREDICTED: sarcolemmal mem (809 aa) initn: 4212 init1: 2571 opt: 4997 Z-score: 1976.4 bits: 376.6 E(85289): 2.4e-103 Smith-Waterman score: 4997; 97.3% identity (97.9% similar) in 816 aa overlap (1-811:1-809) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK--VTH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_005 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKGTVTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE1 KIEALQADNDFTNERLTALQ---EHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEET :::::::::::::::::::: ::: :. .:. . .::::::::::::::: XP_005 KIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSL-------EKLIVEGHLTKAVEET 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 KLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSE 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE1 IEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQL 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE1 QRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKV 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE1 RAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETE 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE1 CHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE1 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLL 720 730 740 750 760 770 780 790 800 810 pF1KE1 REKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP :::::::::::::::::::::::::::::::::::: XP_005 REKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP 780 790 800 >>XP_016862641 (OMIM: 602701) PREDICTED: sarcolemmal mem (808 aa) initn: 4965 init1: 4965 opt: 4975 Z-score: 1967.8 bits: 375.0 E(85289): 7.2e-103 Smith-Waterman score: 4975; 97.9% identity (98.9% similar) in 802 aa overlap (1-802:1-801) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE1 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE1 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSADLK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE1 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREKGN 730 740 750 760 770 780 790 800 810 pF1KE1 NKPWPWMPMLAALVAVTAIVLYVPGLARASP : : .:. :..... :. XP_016 N-PSILQPVPAVFIGLFLAFLFWCFGPLW 790 800 >>XP_011532405 (OMIM: 602701) PREDICTED: sarcolemmal mem (809 aa) initn: 4212 init1: 2573 opt: 4974 Z-score: 1967.4 bits: 374.9 E(85289): 7.6e-103 Smith-Waterman score: 4974; 96.9% identity (97.7% similar) in 817 aa overlap (1-811:1-809) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK--VTH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_011 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKGTVTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE1 KIEALQADNDFTNERLTALQ----EHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEE :::::::::::::::::::: . .: : .:. ..:::::::::::::: XP_011 KIEALQADNDFTNERLTALQGIQVDDFLPKINGSTE--------KEKLIVEGHLTKAVEE 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 TKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQS 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE1 EIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQ 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE1 LQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKK 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE1 VRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALET 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE1 ECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLR 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE1 DSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKL 720 730 740 750 760 770 780 790 800 810 pF1KE1 LREKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP ::::::::::::::::::::::::::::::::::::: XP_011 LREKGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP 780 790 800 >>XP_016862640 (OMIM: 602701) PREDICTED: sarcolemmal mem (810 aa) initn: 4174 init1: 4174 opt: 4961 Z-score: 1962.3 bits: 374.0 E(85289): 1.5e-102 Smith-Waterman score: 4961; 97.6% identity (98.6% similar) in 804 aa overlap (1-802:1-803) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRK--VTH ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: XP_016 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKGTVTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCIVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQA 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE1 KIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE1 KENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE1 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE1 HIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAE 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE1 LERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE1 LKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSAD 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE1 LKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLREK 730 740 750 760 770 780 780 790 800 810 pF1KE1 GNNKPWPWMPMLAALVAVTAIVLYVPGLARASP ::: : .:. :..... :. XP_016 GNN-PSILQPVPAVFIGLFLAFLFWCFGPLW 790 800 810 >>XP_016862643 (OMIM: 602701) PREDICTED: sarcolemmal mem (804 aa) initn: 4795 init1: 2446 opt: 4813 Z-score: 1904.7 bits: 363.3 E(85289): 2.3e-99 Smith-Waterman score: 4813; 95.4% identity (97.0% similar) in 805 aa overlap (1-802:1-797) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 390 400 410 pF1KE1 EALQADNDFTNERLTALQ---EHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKL :::::::::::::::::: ::: :. .:. . .::::::::::::::::: XP_016 EALQADNDFTNERLTALQVRLEHLQEKTLKECSSL-------EKLIVEGHLTKAVEETKL 370 380 390 400 410 420 430 440 450 460 470 pF1KE1 SKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIE 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE1 AKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQR 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE1 LHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRA 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE1 ELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECH 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE1 SLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRDSA 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE1 DLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCKNNLKLLRE 720 730 740 750 760 770 780 790 800 810 pF1KE1 KGNNKPWPWMPMLAALVAVTAIVLYVPGLARASP :::: : .:. :..... :. XP_016 KGNN-PSILQPVPAVFIGLFLAFLFWCFGPLW 780 790 800 >>XP_016862644 (OMIM: 602701) PREDICTED: sarcolemmal mem (804 aa) initn: 4347 init1: 2446 opt: 4341 Z-score: 1720.9 bits: 329.3 E(85289): 4.1e-89 Smith-Waterman score: 4744; 91.1% identity (91.1% similar) in 845 aa overlap (1-811:1-804) 10 20 30 40 50 60 pF1KE1 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSALAIFTCRPNSHPFQERHVYLDEPIKIGRSVARCRPAQNNATFDCKVLSRNHALVWF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHKTGKFYLQDTKSSNGTFINSQRLSRGSEESPPCEILSGDIIQFGVDVTENTRKVTHGC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVSTIKLFLPDGMEARLRSDVIHAPLPSPVDKVAANTPSMYSQELFQLSQYLQEALHREQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLRKEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQEEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAKI 310 320 330 340 350 360 370 380 pF1KE1 EALQADNDFTNERLTALQ----------------------------------EHLLSKSG :::::::::::::::::: :::::::: XP_016 EALQADNDFTNERLTALQVRLEHLQEKTLKECSSLGIQVDDFLPKINGSTEKEHLLSKSG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KE1 GDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTT 430 440 450 460 470 480 450 460 470 480 490 500 pF1KE1 DAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFEL :::::::::::::::::::: XP_016 DAQMDEQDLNEPLAKVSLLK---------------------------------------- 490 500 510 520 530 540 550 560 pF1KE1 QALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -ALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDE 510 520 530 540 550 570 580 590 600 610 620 pF1KE1 ILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQ 560 570 580 590 600 610 630 640 650 660 670 680 pF1KE1 CEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLE 620 630 640 650 660 670 690 700 710 720 730 740 pF1KE1 LTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTSDLSILQMSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDVQKEYEKTQTVLSE 680 690 700 710 720 730 750 760 770 780 790 800 pF1KE1 LKLKFEMTEQEKQSITDELKQCKNNLKLLREKGNNKPWPWMPMLAALVAVTAIVLYVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKLKFEMTEQEKQSITDELKQCKNNLKLLREKGNNKPWPWMPMLAALVAVTAIVLYVPGL 740 750 760 770 780 790 810 pF1KE1 ARASP ::::: XP_016 ARASP 800 811 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:32:13 2016 done: Sat Nov 5 19:32:15 2016 Total Scan time: 14.760 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]