FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1077, 228 aa 1>>>pF1KE1077 228 - 228 aa - 228 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9269+/-0.000965; mu= 7.9600+/- 0.057 mean_var=215.8712+/-47.686, 0's: 0 Z-trim(112.2): 82 B-trim: 0 in 0/51 Lambda= 0.087292 statistics sampled from 12902 (12975) to 12902 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.399), width: 16 Scan time: 1.920 The best scores are: opt bits E(32554) CCDS33482.1 RNF114 gene_id:55905|Hs108|chr20 ( 228) 1633 217.7 4.8e-57 CCDS10969.1 RNF166 gene_id:115992|Hs108|chr16 ( 237) 752 106.8 1.2e-23 CCDS54056.1 RNF166 gene_id:115992|Hs108|chr16 ( 128) 457 69.3 1.3e-12 CCDS54057.1 RNF166 gene_id:115992|Hs108|chr16 ( 156) 430 66.0 1.5e-11 >>CCDS33482.1 RNF114 gene_id:55905|Hs108|chr20 (228 aa) initn: 1633 init1: 1633 opt: 1633 Z-score: 1137.6 bits: 217.7 E(32554): 4.8e-57 Smith-Waterman score: 1633; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KE1 MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 VKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMP 130 140 150 160 170 180 190 200 210 220 pF1KE1 WGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 WGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ 190 200 210 220 >>CCDS10969.1 RNF166 gene_id:115992|Hs108|chr16 (237 aa) initn: 616 init1: 410 opt: 752 Z-score: 537.8 bits: 106.8 E(32554): 1.2e-23 Smith-Waterman score: 752; 45.2% identity (71.7% similar) in 230 aa overlap (2-225:10-234) 10 20 30 40 50 pF1KE1 MAAQQRDCGGAAQLAGPAAEADPL-GRFTCPVCLEVYEKPVQV-PCGHVFCS .::::. ::::. . : ...:::.:::::..:: . :::.::. CCDS10 MAMFRSLVASAQQRQ-----PPAGPAGGDSGLEAQYTCPICLEVYHRPVAIGSCGHTFCG 10 20 30 40 50 60 70 80 90 100 pF1KE1 ACLQECLKPKKPVCGVCRSALAPGV--RAVELERQIESTETSCHGCRKNFFLSKIRSHVA ::: ::. .:.: .:: . : .:...:.:. : .. :.:: :. :.:.: :.. CCDS10 ECLQPCLQVPSPLCPLCRLPFDPKKVDKATHVEKQLSSYKAPCRGCNKKVTLAKMRVHIS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE1 TCSKYQNYIMEGVK--ATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHST .: : :. . . : .. .. : :.::: :: :::: .:.::. ::.:: : . CCDS10 SCLKVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRS 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE1 DTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSII : . ::::::..::::::.:.:::: .:. .::.:::::::::..::: .. .: :. CCDS10 DPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLS 180 190 200 210 220 230 pF1KE1 DQ CCDS10 EN >>CCDS54056.1 RNF166 gene_id:115992|Hs108|chr16 (128 aa) initn: 432 init1: 410 opt: 457 Z-score: 339.9 bits: 69.3 E(32554): 1.3e-12 Smith-Waterman score: 457; 48.0% identity (73.6% similar) in 125 aa overlap (103-225:1-125) 80 90 100 110 120 130 pF1KE1 PGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEGVK--ATIKDASL .: :...: : :. . . : .. .. CCDS54 MRVHISSCLKVQEQMANCPKFVPVVPTSQP 10 20 30 140 150 160 170 180 190 pF1KE1 QPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSAN : :.::: :: :::: .:.::. ::.:: : .: . ::::::..::::::.:.::: CCDS54 IPSNIPNRSTFACPYCGARNLDQQELVKHCVESHRSDPNRVVCPICSAMPWGDPSYKSAN 40 50 60 70 80 90 200 210 220 pF1KE1 FREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ : .:. .::.:::::::::..::: .. .: :. CCDS54 FLQHLLHRHKFSYDTFVDYSIDEEAAFQAALALSLSEN 100 110 120 >>CCDS54057.1 RNF166 gene_id:115992|Hs108|chr16 (156 aa) initn: 506 init1: 410 opt: 430 Z-score: 320.6 bits: 66.0 E(32554): 1.5e-11 Smith-Waterman score: 430; 57.4% identity (79.8% similar) in 94 aa overlap (132-225:60-153) 110 120 130 140 150 160 pF1KE1 KIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCK : :.::: :: :::: .:.::. ::.:: CCDS54 QYTCPICLEVQEQMANCPKFVPVVPTSQPIPSNIPNRSTFACPYCGARNLDQQELVKHCV 30 40 50 60 70 80 170 180 190 200 210 220 pF1KE1 LFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVL : .: . ::::::..::::::.:.:::: .:. .::.:::::::::..::: .. .: CCDS54 ESHRSDPNRVVCPICSAMPWGDPSYKSANFLQHLLHRHKFSYDTFVDYSIDEEAAFQAAL 90 100 110 120 130 140 pF1KE1 QRSIIDQ :. CCDS54 ALSLSEN 150 228 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:34:05 2016 done: Sat Nov 5 19:34:05 2016 Total Scan time: 1.920 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]