Result of FASTA (omim) for
pF1KE1080
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1080, 1258 aa
1>>>pF1KE1080 1258 - 1258 aa - 1258 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8931+/-0.00051; mu= 5.8324+/- 0.032
mean_var=228.6086+/-46.340, 0's: 0 Z-trim(116.2): 82 B-trim: 414 in 2/49
Lambda= 0.084826
statistics sampled from 27074 (27156) to 27074 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.318), width: 16
Scan time: 17.150
The best scores are: opt bits E(85289)
NP_001172003 (OMIM: 613467) terminal uridylyltrans (1259) 8447 1048.3 0
XP_005252265 (OMIM: 613467) PREDICTED: terminal ur (1381) 3101 394.1 3.4e-108
XP_005252264 (OMIM: 613467) PREDICTED: terminal ur (1478) 3101 394.1 3.5e-108
XP_011517318 (OMIM: 613467) PREDICTED: terminal ur (1490) 3101 394.1 3.6e-108
NP_078893 (OMIM: 613467) terminal uridylyltransfer (1495) 3101 394.2 3.6e-108
XP_016870620 (OMIM: 613467) PREDICTED: terminal ur (1495) 3101 394.2 3.6e-108
NP_001171988 (OMIM: 613467) terminal uridylyltrans (1495) 3101 394.2 3.6e-108
XP_016870619 (OMIM: 613467) PREDICTED: terminal ur (1495) 3101 394.2 3.6e-108
XP_011517317 (OMIM: 613467) PREDICTED: terminal ur (1536) 3101 394.2 3.7e-108
XP_006717346 (OMIM: 613467) PREDICTED: terminal ur (1541) 3101 394.2 3.7e-108
XP_011517314 (OMIM: 613467) PREDICTED: terminal ur (1551) 3101 394.2 3.7e-108
XP_011517315 (OMIM: 613467) PREDICTED: terminal ur (1551) 3101 394.2 3.7e-108
XP_011517313 (OMIM: 613467) PREDICTED: terminal ur (1551) 3101 394.2 3.7e-108
XP_011517316 (OMIM: 613467) PREDICTED: terminal ur (1551) 3101 394.2 3.7e-108
NP_001317647 (OMIM: 613467) terminal uridylyltrans ( 784) 2871 365.8 6.5e-100
XP_016856299 (OMIM: 613692) PREDICTED: terminal ur (1529) 1508 199.2 1.8e-49
XP_016856297 (OMIM: 613692) PREDICTED: terminal ur (1536) 1508 199.2 1.8e-49
XP_016856296 (OMIM: 613692) PREDICTED: terminal ur (1569) 1508 199.2 1.8e-49
XP_016856295 (OMIM: 613692) PREDICTED: terminal ur (1576) 1508 199.2 1.8e-49
XP_016856293 (OMIM: 613692) PREDICTED: terminal ur (1613) 1508 199.2 1.8e-49
XP_016856292 (OMIM: 613692) PREDICTED: terminal ur (1620) 1508 199.2 1.8e-49
XP_005270737 (OMIM: 613692) PREDICTED: terminal ur (1640) 1508 199.2 1.9e-49
NP_056084 (OMIM: 613692) terminal uridylyltransfer (1644) 1508 199.2 1.9e-49
XP_005270736 (OMIM: 613692) PREDICTED: terminal ur (1647) 1508 199.2 1.9e-49
XP_005270735 (OMIM: 613692) PREDICTED: terminal ur (1651) 1508 199.2 1.9e-49
XP_016856298 (OMIM: 613692) PREDICTED: terminal ur (1534) 1496 197.7 4.9e-49
XP_005270739 (OMIM: 613692) PREDICTED: terminal ur (1541) 1496 197.7 4.9e-49
XP_011539401 (OMIM: 613692) PREDICTED: terminal ur (1554) 1496 197.7 4.9e-49
XP_006710563 (OMIM: 613692) PREDICTED: terminal ur (1581) 1496 197.8 5e-49
XP_011539400 (OMIM: 613692) PREDICTED: terminal ur (1625) 1496 197.8 5.1e-49
NP_001009881 (OMIM: 613692) terminal uridylyltrans (1645) 1496 197.8 5.2e-49
XP_006710562 (OMIM: 613692) PREDICTED: terminal ur (1652) 1496 197.8 5.2e-49
XP_006710561 (OMIM: 613692) PREDICTED: terminal ur (1652) 1496 197.8 5.2e-49
XP_011539399 (OMIM: 613692) PREDICTED: terminal ur (1652) 1496 197.8 5.2e-49
XP_005270733 (OMIM: 613692) PREDICTED: terminal ur (1652) 1496 197.8 5.2e-49
XP_016856302 (OMIM: 613692) PREDICTED: terminal ur (1518) 1292 172.8 1.6e-41
XP_016856301 (OMIM: 613692) PREDICTED: terminal ur (1522) 1292 172.8 1.6e-41
XP_016856300 (OMIM: 613692) PREDICTED: terminal ur (1523) 1280 171.3 4.4e-41
XP_005270740 (OMIM: 613692) PREDICTED: terminal ur (1530) 1280 171.3 4.4e-41
XP_011539402 (OMIM: 613692) PREDICTED: terminal ur (1304) 1240 166.4 1.2e-39
XP_016856294 (OMIM: 613692) PREDICTED: terminal ur (1602) 885 123.0 1.6e-26
XP_016856303 (OMIM: 613692) PREDICTED: terminal ur (1412) 872 121.4 4.5e-26
XP_005270738 (OMIM: 613692) PREDICTED: terminal ur (1614) 873 121.5 4.5e-26
XP_016856307 (OMIM: 613692) PREDICTED: terminal ur ( 943) 584 86.0 1.3e-15
XP_016856306 (OMIM: 613692) PREDICTED: terminal ur ( 983) 584 86.0 1.4e-15
XP_016856305 (OMIM: 613692) PREDICTED: terminal ur (1027) 584 86.0 1.4e-15
XP_016856304 (OMIM: 613692) PREDICTED: terminal ur (1038) 584 86.0 1.4e-15
XP_011539403 (OMIM: 613692) PREDICTED: terminal ur (1059) 584 86.0 1.5e-15
XP_016864651 (OMIM: 614121) PREDICTED: poly(A) RNA ( 261) 408 64.0 1.6e-09
XP_016864650 (OMIM: 614121) PREDICTED: poly(A) RNA ( 265) 408 64.0 1.6e-09
>>NP_001172003 (OMIM: 613467) terminal uridylyltransfera (1259 aa)
initn: 5514 init1: 5445 opt: 8447 Z-score: 5599.8 bits: 1048.3 E(85289): 0
Smith-Waterman score: 8447; 99.4% identity (99.8% similar) in 1259 aa overlap (1-1258:1-1259)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 RPRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYP
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_001 RPRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TAKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KVVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFP
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 AIIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLILDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLILDV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 KHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSVKR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 NVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHHPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHHPD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 VQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHPEN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNNES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNNES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 ESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEMIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEMIP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 SDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGEAA
730 740 750 760 770 780
790 800 810 820 830
pF1KE1 KYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGKGLDC
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_001 KYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKGLDC
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE1 VRTIEELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSA
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_001 VRTIEELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE1 YSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIY
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE1 KGEEKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVI
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGEKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVI
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE1 SIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVK
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE1 GFSKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDAL
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFPKDYPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDAL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE1 NQRYPENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQRYPENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPP
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE1 VEKWKRQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEKWKRQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1210 1220 1230 1240 1250
>>XP_005252265 (OMIM: 613467) PREDICTED: terminal uridyl (1381 aa)
initn: 7535 init1: 2966 opt: 3101 Z-score: 2063.5 bits: 394.1 E(85289): 3.4e-108
Smith-Waterman score: 6421; 80.9% identity (81.3% similar) in 1276 aa overlap (92-1130:92-1367)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_005 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_005 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_005 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_005 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_005 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_005 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_005 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_005 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
:::::::::::::::::::::::::::::::::::::::::::..:
XP_005 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRNTRATLKMKKKNCTLKP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.8 bits: 94.1 E(85289): 7.2e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_005 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_005 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_005 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>>XP_005252264 (OMIM: 613467) PREDICTED: terminal uridyl (1478 aa)
initn: 8170 init1: 2966 opt: 3101 Z-score: 2063.1 bits: 394.1 E(85289): 3.5e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_005 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_005 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_005 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_005 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_005 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_005 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_005 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_005 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_005 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_005 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSAFT
1450 1460 1470
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.4 bits: 94.1 E(85289): 7.6e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_005 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_005 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_005 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 444 init1: 444 opt: 444 Z-score: 305.8 bits: 69.0 E(85289): 2.7e-10
Smith-Waterman score: 444; 100.0% identity (100.0% similar) in 62 aa overlap (1177-1238:1414-1475)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_005 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::::
XP_005 DDKDLREKRCFICGREGHIKKECPQFKGSSGSAFT
1450 1460 1470
>>XP_011517318 (OMIM: 613467) PREDICTED: terminal uridyl (1490 aa)
initn: 8165 init1: 2966 opt: 3101 Z-score: 2063.0 bits: 394.1 E(85289): 3.6e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_011 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_011 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_011 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_011 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_011 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_011 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_011 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_011 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGYHQVFQCQHCSVEREI
1450 1460 1470 1480 1490
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.3 bits: 94.1 E(85289): 7.6e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_011 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_011 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_011 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 439 init1: 439 opt: 439 Z-score: 302.4 bits: 68.4 E(85289): 4.2e-10
Smith-Waterman score: 439; 100.0% identity (100.0% similar) in 61 aa overlap (1177-1237:1414-1474)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_011 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
:::::::::::::::::::::::::::::::
XP_011 DDKDLREKRCFICGREGHIKKECPQFKGSSGYHQVFQCQHCSVEREI
1450 1460 1470 1480 1490
>>NP_078893 (OMIM: 613467) terminal uridylyltransferase (1495 aa)
initn: 8290 init1: 2966 opt: 3101 Z-score: 2063.0 bits: 394.2 E(85289): 3.6e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
NP_078 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_078 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
NP_078 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
NP_078 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_078 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
NP_078 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
NP_078 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_078 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_078 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_078 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
NP_078 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
NP_078 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.3 bits: 94.1 E(85289): 7.7e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_078 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
NP_078 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
NP_078 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 564 init1: 564 opt: 564 Z-score: 385.1 bits: 83.7 E(85289): 1e-14
Smith-Waterman score: 564; 100.0% identity (100.0% similar) in 82 aa overlap (1177-1258:1414-1495)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
NP_078 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>>XP_016870620 (OMIM: 613467) PREDICTED: terminal uridyl (1495 aa)
initn: 8290 init1: 2966 opt: 3101 Z-score: 2063.0 bits: 394.2 E(85289): 3.6e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_016 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_016 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_016 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_016 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_016 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_016 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_016 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_016 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.3 bits: 94.1 E(85289): 7.7e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_016 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_016 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 564 init1: 564 opt: 564 Z-score: 385.1 bits: 83.7 E(85289): 1e-14
Smith-Waterman score: 564; 100.0% identity (100.0% similar) in 82 aa overlap (1177-1258:1414-1495)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_016 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>>NP_001171988 (OMIM: 613467) terminal uridylyltransfera (1495 aa)
initn: 8290 init1: 2966 opt: 3101 Z-score: 2063.0 bits: 394.2 E(85289): 3.6e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
NP_001 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_001 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
NP_001 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
NP_001 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
NP_001 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
NP_001 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_001 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
NP_001 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
NP_001 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.3 bits: 94.1 E(85289): 7.7e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
NP_001 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
NP_001 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 564 init1: 564 opt: 564 Z-score: 385.1 bits: 83.7 E(85289): 1e-14
Smith-Waterman score: 564; 100.0% identity (100.0% similar) in 82 aa overlap (1177-1258:1414-1495)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
NP_001 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>>XP_016870619 (OMIM: 613467) PREDICTED: terminal uridyl (1495 aa)
initn: 8290 init1: 2966 opt: 3101 Z-score: 2063.0 bits: 394.2 E(85289): 3.6e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_016 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_016 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_016 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_016 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_016 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_016 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_016 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_016 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_016 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.3 bits: 94.1 E(85289): 7.7e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_016 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_016 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_016 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 564 init1: 564 opt: 564 Z-score: 385.1 bits: 83.7 E(85289): 1e-14
Smith-Waterman score: 564; 100.0% identity (100.0% similar) in 82 aa overlap (1177-1258:1414-1495)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_016 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
1450 1460 1470 1480 1490
>>XP_011517317 (OMIM: 613467) PREDICTED: terminal uridyl (1536 aa)
initn: 8165 init1: 2966 opt: 3101 Z-score: 2062.9 bits: 394.2 E(85289): 3.7e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_011 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_011 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_011 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_011 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_011 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_011 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_011 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_011 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_011 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGMSKSDCMFGSPSPVPLKPTGLFVQAVL
1450 1460 1470 1480 1490 1500
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.1 bits: 94.1 E(85289): 7.8e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_011 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_011 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_011 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 439 init1: 439 opt: 442 Z-score: 304.2 bits: 68.8 E(85289): 3.3e-10
Smith-Waterman score: 442; 92.6% identity (94.1% similar) in 68 aa overlap (1177-1244:1414-1481)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_011 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::: .: :
XP_011 DDKDLREKRCFICGREGHIKKECPQFKGSSGMSKSDCMFGSPSPVPLKPTGLFVQAVLLH
1450 1460 1470 1480 1490 1500
XP_011 EDKKKQKTTIFLSPQSGYHQVFQCQHCSVEREI
1510 1520 1530
>>XP_006717346 (OMIM: 613467) PREDICTED: terminal uridyl (1541 aa)
initn: 8165 init1: 2966 opt: 3101 Z-score: 2062.8 bits: 394.2 E(85289): 3.7e-108
Smith-Waterman score: 6742; 81.7% identity (82.0% similar) in 1322 aa overlap (92-1176:92-1413)
70 80 90 100 110 120
pF1KE1 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
::::::::::::::::::::::::::::::
XP_006 GNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGPR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PRKPRKTRNEENEQDGDLEGPVIDESALSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
XP_006 PRKPRKTRNEENEQDGDLEGPVIDESVLSTKELLGLQQAEERLKRDCIDRLKRRPRNYPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKYTCRLCDVLIESIAFAHKHIKEKRHKKNIKEKQEEELLTTLPPPTPSQINAVGIAIDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 VVQEFGLHNESLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVQEFGLHNENLEQRLEIKRIMENVFQHKLPDCSLRLYGSSCSRLGFKNSDVNIDIQFPA
310 320 330 340 350 360
pF1KE1 I-----------------------------------------------------------
:
XP_006 IMSQPDVLLLVQECLKNSDSFIDVDADFHARVPVVVCREKQSGLLCKVSAGNENACLTTK
370 380 390 400 410 420
pF1KE1 ------------------------------------------------------------
XP_006 HLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPPYVFALMAIFFLQQRKEPLLPVY
430 440 450 460 470 480
370 380 390 400 410
pF1KE1 ----IEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGSWIEGFSLSKLGNFNLQDIEKDVVIWEHTDSAAGDTGITKEEAPRETPIKRGQVSLIL
490 500 510 520 530 540
420 430 440 450 460 470
pF1KE1 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVKHQPSVPVGQLWVELLRFYALEFNLADLVISIRVKELVSRELKDWPKKRIAIEDPYSV
550 560 570 580 590 600
480 490 500 510 520 530
pF1KE1 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KRNVARTLNSQPVFEYILHCLRTTYKYFALPHKITKSSLLKPLNAITCISEHSKEVINHH
610 620 630 640 650 660
540 550 560 570 580 590
pF1KE1 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDVQTKDDKLKNSVLAQGPGATSSAANTCKVQPLTLKETAESFGSPPKEEMGNEHISVHP
670 680 690 700 710 720
600 610 620 630 640 650
pF1KE1 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENSDCIQADVNSDDYKGDKVYHPETGRKNEKEKVGRKGKHLLTVDQKRGEHVVCGSTRNN
730 740 750 760 770 780
660 670 680 690 700 710
pF1KE1 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESESTLDLEGFQNPTAKECEGLATLDNKADLDGESTEGTEELEDSLNHFTHSVQGQTSEM
790 800 810 820 830 840
720 730 740 750 760 770
pF1KE1 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPSDEEEEDDEEEEEEEEPRLTINQREDEDGMANEDELDNTYTGSGDEDALSEEDDELGE
850 860 870 880 890 900
780 790 800 810 820 830
pF1KE1 AAKYEDVKECGKHVERALLVELNKISLKEENVCEE-NSPVDQSDFFYEFSKLIFTKGK--
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_006 AAKYEDVKECGKHVERALLVELNKISLKEENVCEEKNSPVDQSDFFYEFSKLIFTKGKSP
910 920 930 940 950 960
pF1KE1 ------------------------------------------------------------
XP_006 TVVCSLCKREGHLKKDCPEDFKRIQLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQA
970 980 990 1000 1010 1020
840
pF1KE1 ---------------------------------------------------GLDCVRTIE
:::::::::
XP_006 REHIRQNLESFIRQDFPGTKLSLFGSSKNGFGFKQSDLDVCMTINGLETAEGLDCVRTIE
1030 1040 1050 1060 1070 1080
850 860 870 880 890 900
pF1KE1 ELARVLRKHSGLRNILPITTAKMPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_006 ELARVLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAID
1090 1100 1110 1120 1130 1140
910 920 930 940 950 960
pF1KE1 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_006 PRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEIYKGEKK
1150 1160 1170 1180 1190 1200
970 980 990 1000 1010 1020
pF1KE1 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRK
1210 1220 1230 1240 1250 1260
1030 1040 1050 1060 1070 1080
pF1KE1 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 SLLTTFKKQWTSKYIVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPVKGFPKD
1270 1280 1290 1300 1310 1320
1090 1100 1110 1120 1130 1140
pF1KE1 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPSKMEYFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCPMRRKVRRRRDQEDALNQRYP
1330 1340 1350 1360 1370 1380
1150 1160 1170 1180 1190 1200
pF1KE1 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
::::::::::::::::::::::::::::::::
XP_006 ENKEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWK
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
XP_006 RQDDKDLREKRCFICGREGHIKKECPQFKGSSGMSKSDCMFGSPSPVPLKPTGLFVQAVL
1450 1460 1470 1480 1490 1500
>--
initn: 649 init1: 649 opt: 649 Z-score: 441.1 bits: 94.1 E(85289): 7.8e-18
Smith-Waterman score: 649; 98.9% identity (100.0% similar) in 91 aa overlap (1-91:1-91)
10 20 30 40 50 60
pF1KE1 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGGKMEKGLQKKKITPGN
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
XP_006 MGDTAKPYFVKRTKDRGTMDDDDFRRGHPQQDYLIIDDHAKGHGSKMEKGLQKKKITPGN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
:::::::::::::::::::::::::::::::
XP_006 YGNTPRKGPCAVSSNPYAFKNPIYSQPAWMNDSHKDQSKRWLSDEHTGNSDNWREFKPGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
XP_006 RIPVINRQRKDSFQENEDGYRWQDTRGCRTVRRLFHKDLTSLETTSEMEAGSPENKKQRS
130 140 150 160 170 180
>--
initn: 439 init1: 439 opt: 442 Z-score: 304.2 bits: 68.8 E(85289): 3.3e-10
Smith-Waterman score: 442; 92.6% identity (94.1% similar) in 68 aa overlap (1177-1244:1414-1481)
1150 1160 1170 1180 1190 1200
pF1KE1 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
::::::::::::::::::::::::::::::
XP_006 KEKRSKEDKEIHNKYTEREVSTKEDKPIQCTPQKAKPMRAAADLGREKILRPPVEKWKRQ
1390 1400 1410 1420 1430 1440
1210 1220 1230 1240 1250
pF1KE1 DDKDLREKRCFICGREGHIKKECPQFKGSSGSLSSKYMTQGKASAKRTQQES
::::::::::::::::::::::::::::::: .: :
XP_006 DDKDLREKRCFICGREGHIKKECPQFKGSSGMSKSDCMFGSPSPVPLKPTGLFVQAVLLH
1450 1460 1470 1480 1490 1500
XP_006 EDKKKQKTTIFLSPQSGSLSSKYMTQGKASAKRTQQES
1510 1520 1530 1540
1258 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 23:15:57 2016 done: Sat Nov 5 23:16:00 2016
Total Scan time: 17.150 Total Display time: 0.770
Function used was FASTA [36.3.4 Apr, 2011]