FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1082, 439 aa 1>>>pF1KE1082 439 - 439 aa - 439 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.4188+/-0.000774; mu= 5.2118+/- 0.047 mean_var=182.7195+/-36.269, 0's: 0 Z-trim(115.1): 20 B-trim: 37 in 1/53 Lambda= 0.094882 statistics sampled from 15687 (15702) to 15687 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.482), width: 16 Scan time: 3.850 The best scores are: opt bits E(32554) CCDS6359.2 MYC gene_id:4609|Hs108|chr8 ( 454) 2925 412.1 5.7e-115 CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 ( 464) 468 75.8 1e-13 >>CCDS6359.2 MYC gene_id:4609|Hs108|chr8 (454 aa) initn: 2925 init1: 2925 opt: 2925 Z-score: 2177.6 bits: 412.1 E(32554): 5.7e-115 Smith-Waterman score: 2925; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:16-454) 10 20 30 40 pF1KE1 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP ::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAP 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 SEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTEL 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE1 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPA 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE1 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE1 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 STESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAG 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE1 GHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 GHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSP 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE1 RSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 RSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILS 370 380 390 400 410 420 410 420 430 pF1KE1 VQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA :::::::::::::::::::::::::::::::::: CCDS63 VQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA 430 440 450 >>CCDS1687.1 MYCN gene_id:4613|Hs108|chr2 (464 aa) initn: 791 init1: 360 opt: 468 Z-score: 359.8 bits: 75.8 E(32554): 1e-13 Smith-Waterman score: 872; 40.7% identity (62.1% similar) in 477 aa overlap (10-438:15-464) 10 20 30 40 50 pF1KE1 MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFEL .: ::..::.:: :: ::.. :: .: : :.::::::::: CCDS16 MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDD-FYFGGPDS---TP-PGEDIWKKFEL 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 LPTPPLSPSRRSGLCS---PSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVN :::::::::: . : ::.: : . : .:. : : :.. . ::: : CCDS16 LPTPPLSPSRGFAEHSSEPPSWV--TEMLL--ENELWG---SPAEEDAFGLGGLGGLTPN 60 70 80 90 100 120 130 140 150 160 pF1KE1 QSFICDPDDETFIKNIIIQDCMWSGFSAAAKL---VSEKL--------ASYQAARKDSGS : .:.:::::::::: :: ::::: :. : .:. CCDS16 ------P--------VILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGA 110 120 130 140 150 170 180 190 200 210 pF1KE1 PNPA-RGHSVCS----TSSLYLQDLSAAASECIDPSVVFPYPLNDSS-SPKSCASQDSSA .:: :::. . ... .:. :.::.::.::::.:.: .: : .. : CCDS16 ASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPA 160 170 180 190 200 210 220 230 240 250 260 pF1KE1 FSPS--SDSLLSSTESSPQ-GSPEP------------LVLHEETPPTTSSDSEEEQEDEE .:. : . ... ..: . :.: : : . :.: ..:.:::: CCDS16 AGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEE 220 230 240 250 260 270 270 280 290 300 310 pF1KE1 E-IDVVSVEKRQAPGKRSESGS------P--SAGGHSKPPHSPLVLKRCHVSTHQHNYAA : ::::.::::.. .. . . : .: : .. : :.:::: .:::::: CCDS16 EEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCLPIHQQHNYAA 280 290 300 310 320 330 320 330 340 350 360 pF1KE1 P-PSTR-KDYPAAKRVKLD-SVRVLRQISNNR-KCTSPRSSDTEENVKRRTHNVLERQRR : : .. .: : :..: . : : :... . : :::.::.:.. .::.::.:::::: CCDS16 PSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRR 340 350 360 370 380 390 370 380 390 400 410 420 pF1KE1 NELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQL :.:. ::..:::..::: .:::: ::::::::: :. :.::::..:. :.. :. :..:: CCDS16 NDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQL 400 410 420 430 440 450 430 pF1KE1 KHKLEQLRNSCA .:.:. : .: CCDS16 LKKIEHAR-TC 460 439 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:02:25 2016 done: Sat Nov 5 19:02:26 2016 Total Scan time: 3.850 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]