FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1095, 360 aa 1>>>pF1KE1095 360 - 360 aa - 360 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1783+/-0.000954; mu= 11.2728+/- 0.057 mean_var=71.3477+/-14.779, 0's: 0 Z-trim(105.6): 52 B-trim: 239 in 1/48 Lambda= 0.151839 statistics sampled from 8465 (8508) to 8465 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.261), width: 16 Scan time: 2.320 The best scores are: opt bits E(32554) CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX ( 360) 2429 541.4 4.4e-154 CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX ( 361) 2417 538.8 2.7e-153 CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 ( 344) 858 197.3 1.7e-50 CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 ( 364) 356 87.3 2.2e-17 CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 ( 446) 356 87.3 2.7e-17 CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 ( 384) 319 79.2 6.5e-15 CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 ( 425) 319 79.2 7.1e-15 CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 ( 436) 319 79.2 7.3e-15 CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 ( 443) 319 79.2 7.4e-15 CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 ( 454) 319 79.2 7.6e-15 >>CCDS35250.1 WDR45 gene_id:11152|Hs108|chrX (360 aa) initn: 2429 init1: 2429 opt: 2429 Z-score: 2879.7 bits: 541.4 E(32554): 4.4e-154 Smith-Waterman score: 2429; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 NLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 NRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 NRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 TSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 TSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 YCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 YCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 TVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 TVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF 310 320 330 340 350 360 >>CCDS14318.1 WDR45 gene_id:11152|Hs108|chrX (361 aa) initn: 1906 init1: 1906 opt: 2417 Z-score: 2865.5 bits: 538.8 E(32554): 2.7e-153 Smith-Waterman score: 2417; 99.7% identity (99.7% similar) in 361 aa overlap (1-360:1-361) 10 20 30 40 50 60 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 NLLALVGGGSSPKFSEIS-VLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: CCDS14 NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD 310 320 330 340 350 360 360 pF1KE1 F : CCDS14 F >>CCDS11815.2 WDR45B gene_id:56270|Hs108|chr17 (344 aa) initn: 731 init1: 359 opt: 858 Z-score: 1020.2 bits: 197.3 E(32554): 1.7e-50 Smith-Waterman score: 1101; 47.9% identity (75.5% similar) in 351 aa overlap (8-357:12-342) 10 20 30 40 50 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM :. ::::..:: :.::.: :.::..:: :: . . . :..: ::: CCDS11 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV : : : :::::::..::. .:.:::: :.: :.:. :. : .:..:.:.:: CCDS11 LFRCNYLALVGGGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS .:: . : :..: ::..: :.: :::::: :::. ...::.::: . : .::::::: CCDS11 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE1 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT : :: : : ::.. ..:..:: :: .:.::.::::::.:::.: . . :::::. CCDS11 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS 180 190 200 210 220 240 250 260 270 280 290 pF1KE1 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW . :..:::::..:.:..:.:::.::::::: .: . :..:.:: .. .. .: .:.: CCDS11 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE1 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC :...: ::. : :::::: . :.:::::.::...:..:.: :.: :... .:.. CCDS11 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT 290 300 310 320 330 340 360 pF1KE1 DDDDF :: CCDS11 DDKL >>CCDS82193.1 WIPI1 gene_id:55062|Hs108|chr17 (364 aa) initn: 240 init1: 152 opt: 356 Z-score: 425.4 bits: 87.3 E(32554): 2.2e-17 Smith-Waterman score: 356; 35.7% identity (67.0% similar) in 182 aa overlap (96-273:12-186) 70 80 90 100 110 120 pF1KE1 VGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYV . ...... .::.:. ...... :.. ::. CCDS82 MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYI 10 20 30 40 130 140 150 160 170 180 pF1KE1 YSFPDNPRKLFE--FDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTS ... : ::.. .: :: ::: : . .. :..:: : . : : : : CCDS82 HNIKDM--KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK---- 50 60 70 80 90 190 200 210 220 230 240 pF1KE1 SAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDP-ATLY . :: ::.. .: ...: :. .::::.:::.::.:.. . .:: :.::: .:. CCDS82 -TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTIS 100 110 120 130 140 150 250 260 270 280 290 300 pF1KE1 CINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFT . :: ::.::::::. ::::: :... .: CCDS82 SLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSD 160 170 180 190 200 210 310 320 330 340 350 360 pF1KE1 VPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF CCDS82 MMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKT 220 230 240 250 260 270 >>CCDS11677.1 WIPI1 gene_id:55062|Hs108|chr17 (446 aa) initn: 271 init1: 152 opt: 356 Z-score: 424.0 bits: 87.3 E(32554): 2.7e-17 Smith-Waterman score: 395; 30.3% identity (63.8% similar) in 271 aa overlap (9-273:17-268) 10 20 30 40 50 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPL--MEKGHLDHEQVGS .. . :::: . . . ..: ..... . ... : ..: . . CCDS11 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNE-IPD 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRM . .:: : :.:...: : : ...: . ..: . . ...... .::.:. CCDS11 VYIVERLFSSSLVVVV---SHTKPRQMNVYHF---KKGTE-----ICNYSYSSNILSIRL 60 70 80 90 100 120 130 140 150 160 pF1KE1 RHDKIVIVLKNRIYVYSFPDNPRKLFE--FDTRDNPKGLCDLCPSLEKQLLVFPGH-KCG ...... :.. ::.... : ::.. .: :: ::: : . .. :..:: : CCDS11 NRQRLLVCLEESIYIHNIKDM--KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSG 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE1 SLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEK . : : : : . :: ::.. .: ...: :. .::::.:::.::.:.. . .: CCDS11 EIVLYDGNSLK-----TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQK 170 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 LVELRRGTDP-ATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPM : :.::: .:. . :: ::.::::::. ::::: :... .: CCDS11 LYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGK 230 240 250 260 270 280 290 300 310 320 330 340 pF1KE1 IGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNRE CCDS11 MFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMY 290 300 310 320 330 340 >>CCDS47533.1 WIPI2 gene_id:26100|Hs108|chr7 (384 aa) initn: 260 init1: 138 opt: 319 Z-score: 381.3 bits: 79.2 E(32554): 6.5e-15 Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (53-343:19-308) 30 40 50 60 70 80 pF1KE1 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW .:: : :.:.:.:. ..:. .. . CCDS47 MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF-- 10 20 30 40 90 100 110 120 130 140 pF1KE1 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD ..: . . ...... .:.:.. ...... :.. .:.... : .: CCDS47 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 50 60 70 80 90 150 160 170 180 190 200 pF1KE1 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN :: ::: : . .. :..:: : .:. : . . : : ::.: .: .... CCDS47 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE1 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT :: .:.::.:::.::.:. .:: :.:::. . : . :: :. :: :::. : CCDS47 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET 160 170 180 190 200 210 270 280 290 300 pF1KE1 VHIFALKDTRLNR----RSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA :::: :. .. . . . ::: .:. :: . .:. .: CCDS47 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE1 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF ::... : ... ... .:: .. : . :. :.: CCDS47 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA 280 290 300 310 320 330 CCDS47 SHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 340 350 360 370 380 >>CCDS47532.1 WIPI2 gene_id:26100|Hs108|chr7 (425 aa) initn: 293 init1: 138 opt: 319 Z-score: 380.5 bits: 79.2 E(32554): 7.1e-15 Smith-Waterman score: 359; 25.9% identity (57.3% similar) in 351 aa overlap (14-343:20-349) 10 20 30 40 50 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPL--MEKGH--LDHEQVGS ::::.. . . ..: ..... . .:. . : :.: CCDS47 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDV-- 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRM .:: : :.:.:.:. ..:. .. . ..: . . ...... .:.:.. CCDS47 -CIVERLFSSSLVAIVSL-KAPRKLKVCHF-----KKGTE-----ICNYSYSNTILAVKL 60 70 80 90 100 120 130 140 150 160 pF1KE1 RHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSL ...... :.. .:.... : .: :: ::: : . .. :..:: : . CCDS47 NRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEV 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE1 QLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLV :. : . . : : ::.: .: .... :: .:.::.:::.::.:. .:: CCDS47 QVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 ELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTRLNR----RSALARVGKVG :.:::. . : . :: :. :: :::. ::::: :. .. . . . ::: CCDS47 EFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVL 230 240 250 260 270 280 290 300 310 320 330 pF1KE1 PMIGQYVDSQWS--------LASFTVP-AESACICAFGRNTSKNVNSVIAICVDGTFHKY .:. :: . .:. .: ::... : ... ... .:: .. : CCDS47 MASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLA--TIQKIPRLLVGAADGYLYMY 290 300 310 320 330 340 350 360 pF1KE1 VFTPD--GNCNREAFDVYLDICDDDDF . :. :.: CCDS47 NLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGG 340 350 360 370 380 390 >>CCDS34593.1 WIPI2 gene_id:26100|Hs108|chr7 (436 aa) initn: 293 init1: 138 opt: 319 Z-score: 380.3 bits: 79.2 E(32554): 7.3e-15 Smith-Waterman score: 359; 25.9% identity (57.3% similar) in 351 aa overlap (14-343:20-349) 10 20 30 40 50 pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPL--MEKGH--LDHEQVGS ::::.. . . ..: ..... . .:. . : :.: CCDS34 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDV-- 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRM .:: : :.:.:.:. ..:. .. . ..: . . ...... .:.:.. CCDS34 -CIVERLFSSSLVAIVSL-KAPRKLKVCHF-----KKGTE-----ICNYSYSNTILAVKL 60 70 80 90 100 120 130 140 150 160 pF1KE1 RHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSL ...... :.. .:.... : .: :: ::: : . .. :..:: : . CCDS34 NRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEV 110 120 130 140 150 160 170 180 190 200 210 220 pF1KE1 QLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLV :. : . . : : ::.: .: .... :: .:.::.:::.::.:. .:: CCDS34 QVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLF 170 180 190 200 210 220 230 240 250 260 270 280 pF1KE1 ELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTRLNR----RSALARVGKVG :.:::. . : . :: :. :: :::. ::::: :. .. . . . ::: CCDS34 EFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVL 230 240 250 260 270 280 290 300 310 320 330 pF1KE1 PMIGQYVDSQWS--------LASFTVP-AESACICAFGRNTSKNVNSVIAICVDGTFHKY .:. :: . .:. .: ::... : ... ... .:: .. : CCDS34 MASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLA--TIQKIPRLLVGAADGYLYMY 290 300 310 320 330 340 350 360 pF1KE1 VFTPD--GNCNREAFDVYLDICDDDDF . :. :.: CCDS34 NLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRL 340 350 360 370 380 390 >>CCDS47531.1 WIPI2 gene_id:26100|Hs108|chr7 (443 aa) initn: 260 init1: 138 opt: 319 Z-score: 380.2 bits: 79.2 E(32554): 7.4e-15 Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (53-343:78-367) 30 40 50 60 70 80 pF1KE1 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW .:: : :.:.:.:. ..:. .. . CCDS47 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF-- 50 60 70 80 90 100 90 100 110 120 130 140 pF1KE1 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD ..: . . ...... .:.:.. ...... :.. .:.... : .: CCDS47 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 110 120 130 140 150 150 160 170 180 190 200 pF1KE1 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN :: ::: : . .. :..:: : .:. : . . : : ::.: .: .... CCDS47 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD 160 170 180 190 200 210 210 220 230 240 250 260 pF1KE1 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT :: .:.::.:::.::.:. .:: :.:::. . : . :: :. :: :::. : CCDS47 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET 220 230 240 250 260 270 270 280 290 300 pF1KE1 VHIFALKDTRLNR----RSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA :::: :. .. . . . ::: .:. :: . .:. .: CCDS47 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK 280 290 300 310 320 330 310 320 330 340 350 360 pF1KE1 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF ::... : ... ... .:: .. : . :. :.: CCDS47 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA 340 350 360 370 380 CCDS47 SHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 390 400 410 420 430 440 >>CCDS5339.1 WIPI2 gene_id:26100|Hs108|chr7 (454 aa) initn: 260 init1: 138 opt: 319 Z-score: 380.0 bits: 79.2 E(32554): 7.6e-15 Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (53-343:78-367) 30 40 50 60 70 80 pF1KE1 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW .:: : :.:.:.:. ..:. .. . CCDS53 GSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF-- 50 60 70 80 90 100 90 100 110 120 130 140 pF1KE1 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD ..: . . ...... .:.:.. ...... :.. .:.... : .: CCDS53 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 110 120 130 140 150 150 160 170 180 190 200 pF1KE1 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN :: ::: : . .. :..:: : .:. : . . : : ::.: .: .... CCDS53 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD 160 170 180 190 200 210 210 220 230 240 250 260 pF1KE1 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT :: .:.::.:::.::.:. .:: :.:::. . : . :: :. :: :::. : CCDS53 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET 220 230 240 250 260 270 270 280 290 300 pF1KE1 VHIFALKDTRLNR----RSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA :::: :. .. . . . ::: .:. :: . .:. .: CCDS53 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK 280 290 300 310 320 330 310 320 330 340 350 360 pF1KE1 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF ::... : ... ... .:: .. : . :. :.: CCDS53 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA 340 350 360 370 380 CCDS53 SHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPM 390 400 410 420 430 440 360 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:08:02 2016 done: Sat Nov 5 19:08:02 2016 Total Scan time: 2.320 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]