Result of FASTA (omim) for pF1KE1095
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1095, 360 aa
  1>>>pF1KE1095 360 - 360 aa - 360 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5332+/-0.000404; mu= 15.3726+/- 0.025
 mean_var=81.7771+/-17.242, 0's: 0 Z-trim(112.4): 79  B-trim: 831 in 1/54
 Lambda= 0.141827
 statistics sampled from 21171 (21250) to 21171 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.249), width:  16
 Scan time:  8.090

The best scores are:                                      opt bits E(85289)
NP_001025067 (OMIM: 300526,300894) WD repeat domai ( 360) 2429 507.0 2.6e-143
NP_009006 (OMIM: 300526,300894) WD repeat domain p ( 361) 2417 504.6 1.4e-142
XP_005256434 (OMIM: 609226) PREDICTED: WD repeat d ( 310)  858 185.5 1.4e-46
NP_062559 (OMIM: 609226) WD repeat domain phosphoi ( 344)  858 185.6 1.5e-46
XP_016880351 (OMIM: 609226) PREDICTED: WD repeat d ( 226)  767 166.8 4.2e-41
XP_016880352 (OMIM: 609226) PREDICTED: WD repeat d ( 226)  767 166.8 4.2e-41
NP_001307701 (OMIM: 609224) WD repeat domain phosp ( 364)  356 82.9 1.3e-15
NP_060453 (OMIM: 609224) WD repeat domain phosphoi ( 446)  356 82.9 1.5e-15
NP_001028692 (OMIM: 609225) WD repeat domain phosp ( 384)  319 75.3 2.5e-13
NP_001028691 (OMIM: 609225) WD repeat domain phosp ( 425)  319 75.3 2.7e-13
NP_057087 (OMIM: 609225) WD repeat domain phosphoi ( 436)  319 75.3 2.8e-13
NP_001028690 (OMIM: 609225) WD repeat domain phosp ( 443)  319 75.3 2.8e-13
NP_056425 (OMIM: 609225) WD repeat domain phosphoi ( 454)  319 75.4 2.9e-13
XP_016880297 (OMIM: 609224) PREDICTED: WD repeat d ( 318)  293 69.9 8.7e-12
XP_016867441 (OMIM: 609225) PREDICTED: WD repeat d ( 299)  268 64.8 2.9e-10
XP_006715748 (OMIM: 609225) PREDICTED: WD repeat d ( 310)  268 64.8   3e-10
NP_001265228 (OMIM: 609225) WD repeat domain phosp ( 310)  268 64.8   3e-10


>>NP_001025067 (OMIM: 300526,300894) WD repeat domain ph  (360 aa)
 initn: 2429 init1: 2429 opt: 2429  Z-score: 2693.9  bits: 507.0 E(85289): 2.6e-143
Smith-Waterman score: 2429; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)

               10        20        30        40        50        60
pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 NLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 NRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 TSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 YCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASF
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 TVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF
              310       320       330       340       350       360

>>NP_009006 (OMIM: 300526,300894) WD repeat domain phosp  (361 aa)
 initn: 1906 init1: 1906 opt: 2417  Z-score: 2680.6  bits: 504.6 E(85289): 1.4e-142
Smith-Waterman score: 2417; 99.7% identity (99.7% similar) in 361 aa overlap (1-360:1-361)

               10        20        30        40        50        60
pF1KE1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRS
               10        20        30        40        50        60

               70         80        90       100       110         
pF1KE1 NLLALVGGGSSPKFSEIS-VLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL
       :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_009 NLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE1 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKP
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KE1 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPAT
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE1 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLAS
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KE1 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDD
              310       320       330       340       350       360

     360
pF1KE1 F
       :
NP_009 F
        

>>XP_005256434 (OMIM: 609226) PREDICTED: WD repeat domai  (310 aa)
 initn: 739 init1: 359 opt: 858  Z-score: 957.5  bits: 185.5 E(85289): 1.4e-46
Smith-Waterman score: 934; 43.3% identity (68.7% similar) in 351 aa overlap (8-357:12-308)

                   10        20        30        40        50      
pF1KE1     MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
                  :.    ::::..:: :.::.: :.::..:: ::                
XP_005 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEK----------------
               10        20        30        40                    

         60        70        80        90       100       110      
pF1KE1 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV
                          : .:.::::       :.: :.:. :.  : .:..:.:.::
XP_005 -------------------EKQVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV
                              50              60        70         

        120       130       140       150       160       170      
pF1KE1 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS
       .:: . : :..:  ::..:  :.:  :::::: :::. ...::.::: . : .:::::::
XP_005 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS
      80        90       100       110       120       130         

         180       190       200       210       220       230     
pF1KE1 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT
       : ::     :  : ::.. ..:..::  :: .:.::.::::::.:::.: . . :::::.
XP_005 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS
     140            150       160       170       180       190    

         240       250       260       270       280       290     
pF1KE1 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW
       . :..:::::..:.:..:.:::.::::::: .: . :..:.:: ..    .. .: .:.:
XP_005 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW
          200       210       220       230       240           250

         300       310       320       330       340       350     
pF1KE1 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC
       :...: ::. : :::::: .     :.:::::.::...:..:.: :.: :...  .:.. 
XP_005 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT
              260       270           280       290       300      

         360
pF1KE1 DDDDF
       ::   
XP_005 DDKL 
        310 

>>NP_062559 (OMIM: 609226) WD repeat domain phosphoinosi  (344 aa)
 initn: 731 init1: 359 opt: 858  Z-score: 956.9  bits: 185.6 E(85289): 1.5e-46
Smith-Waterman score: 1101; 47.9% identity (75.5% similar) in 351 aa overlap (8-357:12-342)

                   10        20        30        40        50      
pF1KE1     MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
                  :.    ::::..:: :.::.: :.::..:: :: . .  . :..: :::
NP_062 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM
               10        20        30        40        50          

         60        70        80        90       100       110      
pF1KE1 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV
       : : : :::::::..::.   .:.::::       :.: :.:. :.  : .:..:.:.::
NP_062 LFRCNYLALVGGGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV
      60        70        80              90       100       110   

        120       130       140       150       160       170      
pF1KE1 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS
       .:: . : :..:  ::..:  :.:  :::::: :::. ...::.::: . : .:::::::
NP_062 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS
           120       130       140       150       160       170   

         180       190       200       210       220       230     
pF1KE1 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT
       : ::     :  : ::.. ..:..::  :: .:.::.::::::.:::.: . . :::::.
NP_062 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS
                180       190       200       210       220        

         240       250       260       270       280       290     
pF1KE1 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW
       . :..:::::..:.:..:.:::.::::::: .: . :..:.:: ..    .. .: .:.:
NP_062 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW
      230       240       250       260       270           280    

         300       310       320       330       340       350     
pF1KE1 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC
       :...: ::. : :::::: .     :.:::::.::...:..:.: :.: :...  .:.. 
NP_062 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT
          290       300           310       320       330       340

         360
pF1KE1 DDDDF
       ::   
NP_062 DDKL 
            

>>XP_016880351 (OMIM: 609226) PREDICTED: WD repeat domai  (226 aa)
 initn: 592 init1: 359 opt: 767  Z-score: 858.8  bits: 166.8 E(85289): 4.2e-41
Smith-Waterman score: 767; 48.7% identity (77.5% similar) in 236 aa overlap (123-357:2-224)

            100       110       120       130       140       150  
pF1KE1 EKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCP
                                     : :..:  ::..:  :.:  :::::: :::
XP_016                              MIKVFTFTHNPHQLHVFETCYNPKGLCVLCP
                                            10        20        30 

            160       170        180       190       200       210 
pF1KE1 SLEKQLLVFPGHKCGSLQLVDLAST-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASAS
       . ...::.::: . : .:::::::: ::     :  : ::.. ..:..::  :: .:.::
XP_016 NSNNSLLAFPGTHTGHVQLVDLASTEKP-----PVDIPAHEGVLSCIALNLQGTRIATAS
              40        50             60        70        80      

             220       230       240       250       260       270 
pF1KE1 QKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRL
       .::::::.:::.: . . :::::.. :..:::::..:.:..:.:::.::::::: .: . 
XP_016 EKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKR
         90       100       110       120       130       140      

             280       290       300       310       320       330 
pF1KE1 NRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGT
       :..:.:: ..    .. .: .:.::...: ::. : :::::: .     :.:::::.::.
XP_016 NKQSSLASAS----FLPKYFSSKWSFSKFQVPSGSPCICAFGTEP----NAVIAICADGS
        150           160       170       180           190        

             340       350       360
pF1KE1 FHKYVFTPDGNCNREAFDVYLDICDDDDF
       ..:..:.: :.: :...  .:.. ::   
XP_016 YYKFLFNPKGECIRDVYAQFLEMTDDKL 
      200       210       220       

>>XP_016880352 (OMIM: 609226) PREDICTED: WD repeat domai  (226 aa)
 initn: 592 init1: 359 opt: 767  Z-score: 858.8  bits: 166.8 E(85289): 4.2e-41
Smith-Waterman score: 767; 48.7% identity (77.5% similar) in 236 aa overlap (123-357:2-224)

            100       110       120       130       140       150  
pF1KE1 EKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCP
                                     : :..:  ::..:  :.:  :::::: :::
XP_016                              MIKVFTFTHNPHQLHVFETCYNPKGLCVLCP
                                            10        20        30 

            160       170        180       190       200       210 
pF1KE1 SLEKQLLVFPGHKCGSLQLVDLAST-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASAS
       . ...::.::: . : .:::::::: ::     :  : ::.. ..:..::  :: .:.::
XP_016 NSNNSLLAFPGTHTGHVQLVDLASTEKP-----PVDIPAHEGVLSCIALNLQGTRIATAS
              40        50             60        70        80      

             220       230       240       250       260       270 
pF1KE1 QKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRL
       .::::::.:::.: . . :::::.. :..:::::..:.:..:.:::.::::::: .: . 
XP_016 EKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKR
         90       100       110       120       130       140      

             280       290       300       310       320       330 
pF1KE1 NRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGT
       :..:.:: ..    .. .: .:.::...: ::. : :::::: .     :.:::::.::.
XP_016 NKQSSLASAS----FLPKYFSSKWSFSKFQVPSGSPCICAFGTEP----NAVIAICADGS
        150           160       170       180           190        

             340       350       360
pF1KE1 FHKYVFTPDGNCNREAFDVYLDICDDDDF
       ..:..:.: :.: :...  .:.. ::   
XP_016 YYKFLFNPKGECIRDVYAQFLEMTDDKL 
      200       210       220       

>>NP_001307701 (OMIM: 609224) WD repeat domain phosphoin  (364 aa)
 initn: 240 init1: 152 opt: 356  Z-score: 401.4  bits: 82.9 E(85289): 1.3e-15
Smith-Waterman score: 356; 35.7% identity (67.0% similar) in 182 aa overlap (96-273:12-186)

          70        80        90       100       110       120     
pF1KE1 VGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYV
                                     . ...... .::.:. ...... :.. ::.
NP_001                    MNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYI
                                  10        20        30        40 

         130         140       150       160        170       180  
pF1KE1 YSFPDNPRKLFE--FDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTS
       ... :   ::..  .:   :: ::: :  .  .. :..::    : . : :  : :    
NP_001 HNIKDM--KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK----
                50        60        70        80        90         

            190       200       210       220       230        240 
pF1KE1 SAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDP-ATLY
        .  :: ::.. .: ...:  :. .::::.:::.::.:.. . .:: :.:::    .:. 
NP_001 -TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTIS
          100       110       120       130       140       150    

             250       260       270       280       290       300 
pF1KE1 CINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFT
        . :: ::.::::::.  ::::: :...  .:                            
NP_001 SLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSD
          160       170       180       190       200       210    

             310       320       330       340       350       360 
pF1KE1 VPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF 
                                                                   
NP_001 MMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKT
          220       230       240       250       260       270    

>>NP_060453 (OMIM: 609224) WD repeat domain phosphoinosi  (446 aa)
 initn: 271 init1: 152 opt: 356  Z-score: 400.2  bits: 82.9 E(85289): 1.5e-15
Smith-Waterman score: 395; 30.3% identity (63.8% similar) in 271 aa overlap (9-273:17-268)

                       10        20        30          40        50
pF1KE1         MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPL--MEKGHLDHEQVGS
                       .. . :::: . .  . ..: .....  .  ... : ..: . .
NP_060 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNE-IPD
               10        20        30        40        50          

               60        70        80        90       100       110
pF1KE1 MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRM
       . .:: :  :.:...:   :  :  ...:  .   ..: .     . ...... .::.:.
NP_060 VYIVERLFSSSLVVVV---SHTKPRQMNVYHF---KKGTE-----ICNYSYSSNILSIRL
      60        70           80           90            100        

              120       130         140       150       160        
pF1KE1 RHDKIVIVLKNRIYVYSFPDNPRKLFE--FDTRDNPKGLCDLCPSLEKQLLVFPGH-KCG
        ...... :.. ::.... :   ::..  .:   :: ::: :  .  .. :..::    :
NP_060 NRQRLLVCLEESIYIHNIKDM--KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSG
      110       120         130       140       150       160      

       170       180       190       200       210       220       
pF1KE1 SLQLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEK
        . : :  : :     .  :: ::.. .: ...:  :. .::::.:::.::.:.. . .:
NP_060 EIVLYDGNSLK-----TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQK
        170            180       190       200       210       220 

       230        240       250       260       270       280      
pF1KE1 LVELRRGTDP-ATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPM
       : :.:::    .:.  . :: ::.::::::.  ::::: :...  .:             
NP_060 LYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGK
             230       240       250       260       270       280 

        290       300       310       320       330       340      
pF1KE1 IGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNRE
                                                                   
NP_060 MFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMY
             290       300       310       320       330       340 

>>NP_001028692 (OMIM: 609225) WD repeat domain phosphoin  (384 aa)
 initn: 260 init1: 138 opt: 319  Z-score: 360.2  bits: 75.3 E(85289): 2.5e-13
Smith-Waterman score: 335; 26.6% identity (57.1% similar) in 308 aa overlap (53-343:19-308)

             30        40        50        60        70        80  
pF1KE1 CAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSSPKFSEISVLIW
                                     .:: :  :.:.:.:.  ..:.  ..  .  
NP_001             MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSL-KAPRKLKVCHF--
                           10        20        30         40       

             90       100       110       120       130       140  
pF1KE1 DDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRD
          ..: .     . ...... .:.:.. ...... :.. .:.... :        .:  
NP_001 ---KKGTE-----ICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP
             50             60        70        80        90       

            150       160        170       180       190       200 
pF1KE1 NPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAHQSDIACVSLN
       :: ::: :  . ..  :..::    : .:. :  . .     :   : ::.: .: ....
NP_001 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAHDSPLAALAFD
       100       110       120       130            140       150  

             210       220       230       240        250       260
pF1KE1 QPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSSFLCASSDKGT
         :: .:.::.:::.::.:.    .:: :.:::.   .  : . :: :. :: :::.  :
NP_001 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET
            160       170       180       190       200       210  

              270           280       290               300        
pF1KE1 VHIFALKDTRLNR----RSALARVGKVGPMIGQYVDSQWS--------LASFTVP-AESA
       :::: :. .. .      .  .  :::     .:. :: .        .:.  .:     
NP_001 VHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHK
            220       230       240       250       260       270  

       310       320       330       340         350       360     
pF1KE1 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPD--GNCNREAFDVYLDICDDDDF     
        ::...  : ...  ...  .:: .. : . :.  :.:                      
NP_001 NICSLA--TIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSA
              280       290       300       310       320       330

NP_001 SHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
              340       350       360       370       380    

>>NP_001028691 (OMIM: 609225) WD repeat domain phosphoin  (425 aa)
 initn: 293 init1: 138 opt: 319  Z-score: 359.6  bits: 75.3 E(85289): 2.7e-13
Smith-Waterman score: 359; 25.9% identity (57.3% similar) in 351 aa overlap (14-343:20-349)

                     10        20        30          40          50
pF1KE1       MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPL--MEKGH--LDHEQVGS
                          ::::.. .  . ..: .....  .  .:. .   : :.:  
NP_001 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDV--
               10        20        30        40        50          

               60        70        80        90       100       110
pF1KE1 MGLVEMLHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRM
         .:: :  :.:.:.:.  ..:.  ..  .     ..: .     . ...... .:.:..
NP_001 -CIVERLFSSSLVAIVSL-KAPRKLKVCHF-----KKGTE-----ICNYSYSNTILAVKL
        60        70         80             90            100      

              120       130       140       150       160          
pF1KE1 RHDKIVIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSL
        ...... :.. .:.... :        .:  :: ::: :  . ..  :..::    : .
NP_001 NRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEV
        110       120       130       140       150       160      

     170       180       190       200       210       220         
pF1KE1 QLVDLASTKPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLV
       :. :  . .     :   : ::.: .: ....  :: .:.::.:::.::.:.    .:: 
NP_001 QVFDTINLR-----AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLF
        170            180       190       200       210       220 

     230       240        250       260       270           280    
pF1KE1 ELRRGTDPATLYC-INFSHDSSFLCASSDKGTVHIFALKDTRLNR----RSALARVGKVG
       :.:::.   .  : . :: :. :: :::.  ::::: :. .. .      .  .  ::: 
NP_001 EFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVL
             230       240       250       260       270       280 

          290               300        310       320       330     
pF1KE1 PMIGQYVDSQWS--------LASFTVP-AESACICAFGRNTSKNVNSVIAICVDGTFHKY
           .:. :: .        .:.  .:      ::...  : ...  ...  .:: .. :
NP_001 MASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLA--TIQKIPRLLVGAADGYLYMY
             290       300       310         320       330         

         340         350       360                                 
pF1KE1 VFTPD--GNCNREAFDVYLDICDDDDF                                 
        . :.  :.:                                                  
NP_001 NLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGG
     340       350       360       370       380       390         




360 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:08:02 2016 done: Sat Nov  5 19:08:04 2016
 Total Scan time:  8.090 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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