FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1099, 320 aa 1>>>pF1KE1099 320 - 320 aa - 320 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6725+/-0.000338; mu= 13.7788+/- 0.021 mean_var=67.6381+/-12.965, 0's: 0 Z-trim(115.2): 22 B-trim: 0 in 0/53 Lambda= 0.155948 statistics sampled from 25547 (25568) to 25547 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.3), width: 16 Scan time: 6.770 The best scores are: opt bits E(85289) NP_060909 (OMIM: 615319) protein IMPACT [Homo sapi ( 320) 2163 495.4 6.5e-140 XP_016881321 (OMIM: 615319) PREDICTED: protein IMP ( 302) 2043 468.4 8.3e-132 >>NP_060909 (OMIM: 615319) protein IMPACT [Homo sapiens] (320 aa) initn: 2163 init1: 2163 opt: 2163 Z-score: 2632.9 bits: 495.4 E(85289): 6.5e-140 Smith-Waterman score: 2163; 100.0% identity (100.0% similar) in 320 aa overlap (1-320:1-320) 10 20 30 40 50 60 pF1KE1 MAEGDAGSDQRQNEEIEAMAAIYGEEWCVIDDCAKIFCIRISDDIDDPKWTLCLQVMLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAEGDAGSDQRQNEEIEAMAAIYGEEWCVIDDCAKIFCIRISDDIDDPKWTLCLQVMLPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 EYPGTAPPIYQLNAPWLKGQERADLSNSLEEIYIQNIGESILYLWVEKIRDVLIQKSQMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EYPGTAPPIYQLNAPWLKGQERADLSNSLEEIYIQNIGESILYLWVEKIRDVLIQKSQMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 EPGPDVKKKTEEEDVECEDDLILACQPESSVKALDFDISETRTEVEVEELPPIDHGIPIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EPGPDVKKKTEEEDVECEDDLILACQPESSVKALDFDISETRTEVEVEELPPIDHGIPIT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 DRRSTFQAHLAPVVCPKQVKMVLSKLYENKKIASATHNIYAYRIYCEDKQTFLQDCEDDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DRRSTFQAHLAPVVCPKQVKMVLSKLYENKKIASATHNIYAYRIYCEDKQTFLQDCEDDG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 ETAAGGRLLHLMEILNVKNVMVVVSRWYGGILLGPDRFKHINNCARNILVEKNYTNSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ETAAGGRLLHLMEILNVKNVMVVVSRWYGGILLGPDRFKHINNCARNILVEKNYTNSPEE 250 260 270 280 290 300 310 320 pF1KE1 SSKALGKNKKVRKDKKRNEH :::::::::::::::::::: NP_060 SSKALGKNKKVRKDKKRNEH 310 320 >>XP_016881321 (OMIM: 615319) PREDICTED: protein IMPACT (302 aa) initn: 2043 init1: 2043 opt: 2043 Z-score: 2487.4 bits: 468.4 E(85289): 8.3e-132 Smith-Waterman score: 2043; 99.7% identity (100.0% similar) in 302 aa overlap (19-320:1-302) 10 20 30 40 50 60 pF1KE1 MAEGDAGSDQRQNEEIEAMAAIYGEEWCVIDDCAKIFCIRISDDIDDPKWTLCLQVMLPN :::::::::::::::::::::::::::::::::::::::::: XP_016 MAAIYGEEWCVIDDCAKIFCIRISDDIDDPKWTLCLQVMLPN 10 20 30 40 70 80 90 100 110 120 pF1KE1 EYPGTAPPIYQLNAPWLKGQERADLSNSLEEIYIQNIGESILYLWVEKIRDVLIQKSQMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYPGTAPPIYQLNAPWLKGQERADLSNSLEEIYIQNIGESILYLWVEKIRDVLIQKSQMT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 EPGPDVKKKTEEEDVECEDDLILACQPESSVKALDFDISETRTEVEVEELPPIDHGIPIT ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: XP_016 EPGPDVKKKTEEEDVECEDDLILACQPESSLKALDFDISETRTEVEVEELPPIDHGIPIT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 DRRSTFQAHLAPVVCPKQVKMVLSKLYENKKIASATHNIYAYRIYCEDKQTFLQDCEDDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRRSTFQAHLAPVVCPKQVKMVLSKLYENKKIASATHNIYAYRIYCEDKQTFLQDCEDDG 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 ETAAGGRLLHLMEILNVKNVMVVVSRWYGGILLGPDRFKHINNCARNILVEKNYTNSPEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETAAGGRLLHLMEILNVKNVMVVVSRWYGGILLGPDRFKHINNCARNILVEKNYTNSPEE 230 240 250 260 270 280 310 320 pF1KE1 SSKALGKNKKVRKDKKRNEH :::::::::::::::::::: XP_016 SSKALGKNKKVRKDKKRNEH 290 300 320 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 19:12:53 2016 done: Sat Nov 5 19:12:54 2016 Total Scan time: 6.770 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]