FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1125, 572 aa 1>>>pF1KE1125 572 - 572 aa - 572 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.8435+/-0.000466; mu= -28.4889+/- 0.029 mean_var=765.4889+/-155.228, 0's: 0 Z-trim(126.5): 235 B-trim: 0 in 0/60 Lambda= 0.046356 statistics sampled from 52390 (52680) to 52390 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.851), E-opt: 0.2 (0.618), width: 16 Scan time: 12.050 The best scores are: opt bits E(85289) NP_001010972 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 4138 291.8 4.1e-78 NP_003452 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 4138 291.8 4.1e-78 XP_016868076 (OMIM: 602002) PREDICTED: zyxin isofo ( 631) 4138 291.8 4.4e-78 XP_011514871 (OMIM: 602002) PREDICTED: zyxin isofo ( 541) 3049 218.9 3.3e-56 XP_011511130 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_005247510 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_011511129 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_005247508 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_016861869 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_011511135 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_011511122 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_005247503 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_011511133 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_016861867 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_016861868 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_011511136 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 NP_001161143 (OMIM: 600700) lipoma-preferred partn ( 612) 1105 89.0 5e-17 XP_005247507 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 XP_016861866 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 1105 89.0 5e-17 NP_005569 (OMIM: 600700) lipoma-preferred partner ( 612) 1105 89.0 5e-17 XP_011511125 (OMIM: 600700) PREDICTED: lipoma-pref ( 637) 1105 89.0 5.1e-17 XP_016861871 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 1012 82.6 3e-15 XP_011511138 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 1012 82.6 3e-15 NP_003293 (OMIM: 602933) thyroid receptor-interact ( 476) 1011 82.6 3.2e-15 NP_001161144 (OMIM: 600700) lipoma-preferred partn ( 465) 1006 82.2 4e-15 XP_005245966 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 798 68.2 5.3e-11 XP_011539919 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 798 68.2 5.3e-11 XP_016857014 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 798 68.2 5.3e-11 NP_060026 (OMIM: 607747) filamin-binding LIM prote ( 373) 798 68.2 5.3e-11 NP_055055 (OMIM: 604543) LIM domain-containing pro ( 676) 783 67.5 1.6e-10 NP_001019387 (OMIM: 607747) filamin-binding LIM pr ( 276) 733 63.8 8.6e-10 NP_001073905 (OMIM: 614790) Wilms tumor protein 1- ( 430) 737 64.2 9.9e-10 NP_116265 (OMIM: 609066) LIM domain-containing pro ( 538) 686 60.9 1.2e-08 XP_011524754 (OMIM: 614790) PREDICTED: Wilms tumor ( 472) 629 57.0 1.6e-07 XP_006723077 (OMIM: 614790) PREDICTED: Wilms tumor ( 384) 606 55.4 3.9e-07 XP_011524755 (OMIM: 614790) PREDICTED: Wilms tumor ( 231) 520 49.5 1.5e-05 XP_011539920 (OMIM: 607747) PREDICTED: filamin-bin ( 314) 512 49.0 2.7e-05 XP_016857015 (OMIM: 607747) PREDICTED: filamin-bin ( 309) 510 48.9 2.9e-05 XP_016857008 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_005245958 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_005245957 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_005245960 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_011539918 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_016857010 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 NP_001019386 (OMIM: 607747) filamin-binding LIM pr ( 374) 510 49.0 3.3e-05 XP_005245959 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_016857012 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_016857013 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_006710768 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 XP_006710767 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 510 49.0 3.3e-05 >>NP_001010972 (OMIM: 602002) zyxin [Homo sapiens] (572 aa) initn: 4138 init1: 4138 opt: 4138 Z-score: 1523.3 bits: 291.8 E(85289): 4.1e-78 Smith-Waterman score: 4138; 100.0% identity (100.0% similar) in 572 aa overlap (1-572:1-572) 10 20 30 40 50 60 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC 490 500 510 520 530 540 550 560 570 pF1KE1 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT :::::::::::::::::::::::::::::::: NP_001 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT 550 560 570 >>NP_003452 (OMIM: 602002) zyxin [Homo sapiens] (572 aa) initn: 4138 init1: 4138 opt: 4138 Z-score: 1523.3 bits: 291.8 E(85289): 4.1e-78 Smith-Waterman score: 4138; 100.0% identity (100.0% similar) in 572 aa overlap (1-572:1-572) 10 20 30 40 50 60 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC 490 500 510 520 530 540 550 560 570 pF1KE1 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT :::::::::::::::::::::::::::::::: NP_003 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT 550 560 570 >>XP_016868076 (OMIM: 602002) PREDICTED: zyxin isoform X (631 aa) initn: 4138 init1: 4138 opt: 4138 Z-score: 1522.8 bits: 291.8 E(85289): 4.4e-78 Smith-Waterman score: 4138; 100.0% identity (100.0% similar) in 572 aa overlap (1-572:60-631) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVV :::::::::::::::::::::::::::::: XP_016 SGPGRRVCGPGAEAATRDAARTLRPAPGPAMAAPRPSPAISVSVSAPAFYAPQKKFGPVV 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE1 APKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APKPKVNPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALG 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE1 GAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAFPPPPPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDS 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE1 LSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSSLLDDMTKNDPFKARVSSGYVPPPVATPFSSKSSTKPAAGGTAPLPPWKSPSSSQPLP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE1 QVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVPAPAQSQTQFHVQPQPQPKPQVQLHVQSQTQPVSLANTQPRGPPASSPAPAPKFSPVT 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE1 PKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKFTPVASKFSPGAPGGSGSQPNQKLGHPEALSAGTGSPQPPSFTYAQQREKPRVQEKQH 330 340 350 360 370 380 340 350 360 370 380 390 pF1KE1 PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPPPAQNQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQP 390 400 410 420 430 440 400 410 420 430 440 450 pF1KE1 LARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LARAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEP 450 460 470 480 490 500 460 470 480 490 500 510 pF1KE1 ITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITDRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEP 510 520 530 540 550 560 520 530 540 550 560 570 pF1KE1 IMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMPEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARA 570 580 590 600 610 620 pF1KE1 QT :: XP_016 QT 630 >>XP_011514871 (OMIM: 602002) PREDICTED: zyxin isoform X (541 aa) initn: 2954 init1: 2954 opt: 3049 Z-score: 1130.0 bits: 218.9 E(85289): 3.3e-56 Smith-Waterman score: 3870; 94.6% identity (94.6% similar) in 572 aa overlap (1-572:1-541) 10 20 30 40 50 60 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKVNPFRPGDSEPPPAPGAQRAQMGRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPPPPPIEESFPPAPLEEEIFPSPPPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 PEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATP :::::::::::::::: ::::::::::::: XP_011 PEEEGGPEAPIPPPPQ-------------------------------VSSGYVPPPVATP 130 140 190 200 210 220 230 240 pF1KE1 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSSKSSTKPAAGGTAPLPPWKSPSSSQPLPQVPAPAQSQTQFHVQPQPQPKPQVQLHVQS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KE1 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTQPVSLANTQPRGPPASSPAPAPKFSPVTPKFTPVASKFSPGAPGGSGSQPNQKLGHPE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KE1 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSAGTGSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEVEELE 270 280 290 300 310 320 370 380 390 400 410 420 pF1KE1 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLTQQLMQDMEHPQRQNVAVNELCGRCHQPLARAQPAVRALGQLFHIACFTCHQCAQQLQ 330 340 350 360 370 380 430 440 450 460 470 480 pF1KE1 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQQFYSLEGAPYCEGCYTDTLEKCNTCGEPITDRMLRATGKAYHPHCFTCVVCARPLEGT 390 400 410 420 430 440 490 500 510 520 530 540 pF1KE1 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFIVDQANRPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDC 450 460 470 480 490 500 550 560 570 pF1KE1 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT :::::::::::::::::::::::::::::::: XP_011 GKPLSIEADDNGCFPLDGHVLCRKCHTARAQT 510 520 530 540 >>XP_011511130 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_011 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_011 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_011 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_011 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_011 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_011 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_011 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_011 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_011 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_011 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_011 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_011 LTAKASTDL 610 >>XP_005247510 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_005 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_005 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_005 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_005 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_005 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_005 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_005 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_005 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_005 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_005 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_005 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_005 LTAKASTDL 610 >>XP_011511129 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_011 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_011 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_011 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_011 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_011 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_011 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_011 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_011 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_011 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_011 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_011 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_011 LTAKASTDL 610 >>XP_005247508 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_005 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_005 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_005 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_005 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_005 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_005 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_005 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_005 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_005 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_005 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_005 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_005 LTAKASTDL 610 >>XP_016861869 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_016 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_016 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_016 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_016 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_016 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_016 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_016 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_016 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_016 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_016 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_016 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_016 LTAKASTDL 610 >>XP_011511135 (OMIM: 600700) PREDICTED: lipoma-preferre (612 aa) initn: 1012 init1: 761 opt: 1105 Z-score: 426.7 bits: 89.0 E(85289): 5e-17 Smith-Waterman score: 1312; 37.6% identity (59.8% similar) in 627 aa overlap (7-569:31-600) 10 20 30 pF1KE1 MAAPRPSPAISVSVSAPAFYAPQKKFGPVVAPKPKV .:.::::.. : : :::.:::::::: XP_011 MSHPSWLPPKSTGEPLGHVPARMETTHSFGNPSISVSTQQP----P-KKFAPVVAPKPKY 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 NPFRPGDSEPPPAPGAQRAQMGRVGEIPPPPPEDFPLPPPPLAGDGDDAEGALGGAFPPP ::.. ::.. :.. :::: ::: : ..: ...: :::: XP_011 NPYKQ--------PGGE-------GDFLPPPP-------PPL--DDSSALPSISGNFPPP 60 70 80 90 100 110 120 130 140 150 pF1KE1 PPPIEESFPPAPLEEEIFPSPPPPPEEEGGPEAPIPPPPQPREKVSSIDLEIDSLSSLLD :: :.:: : : :: .:. ::.: :::::.:.: XP_011 PP----------LDEEAFKVQGNP----GGKTL--------EERRSSLDAEIDSLTSILA 100 110 120 160 170 180 190 pF1KE1 DMTKNDPFKAR---VSSGYVP-PPVATPFSS----------------KSSTKPAAGGTAP :. ..:.: : :.: . :::.:: .. ::. :: . : XP_011 DLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAG 130 140 150 160 170 180 200 210 220 230 240 pF1KE1 LPPWKSPSSSQPLPQVPAPAQ-------SQTQFHVQPQP-QPKPQVQLHVQS-------- : .. .: :: :.::. :. :.:: . ::.:. . .: XP_011 PIPVAPIGTLKPQPQ-PVPASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGP 190 200 210 220 230 240 250 260 270 280 pF1KE1 ---QTQPVSLANTQP----RG--------PPASSPAPAPKFSPVTPKFTPVASKFSPGAP .:::: ... : :: ::. .: :. ..: .. .:: XP_011 QGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRYYEGYYAAGPGYG 250 260 270 280 290 300 290 300 310 320 330 pF1KE1 GGSGSQPNQ-KLGHPEALS-------AGTGSPQPPSFTYAQQREKPRVQEK-QHPVPPPA : . :.:. . :::.. . :.:. .::.. . .: . . . : :: XP_011 GRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE1 Q----NQNQVRSPGAPGPLTLKEVEELEQLTQQLMQDMEHPQRQNVAVNELCGRCHQPLA : ...:. .:.. .: ... .:::.::.... :::.: .. :.:: . .. XP_011 QPKGGHSGQL-GPSSVAP-SFRPEDELEHLTKKMLYDMENPPADEYFGR--CARCGENVV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE1 RAQPAVRALGQLFHIACFTCHQCAQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGEPIT . :. :.::. :::: : ..:.:: ::..: ::: :: .:::.::.:..:: XP_011 GEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQCNVCSKPIM 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE1 DRMLRATGKAYHPHCFTCVVCARPLEGTSFIVDQANRPHCVPDYHKQYAPRCSVCSEPIM .:.::::::::::::::::.: : :.: : :: .. ::. :.::..:::::::.:::: XP_011 ERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIM 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE1 PEPGRDETVRVVALDKNFHMKCYKCEDCGKPLSIEADDNGCFPLDGHVLCRKCHTARAQT : ::..::::.::::..::..::.::::: :: :.:..::.:::::.::. :..:: XP_011 PAPGQEETVRIVALDRDFHVHCYRCEDCGGLLS-EGDNQGCYPLDGHILCKTCNSARIRV 550 560 570 580 590 600 XP_011 LTAKASTDL 610 572 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 02:07:08 2016 done: Mon Nov 7 02:07:10 2016 Total Scan time: 12.050 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]