FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1218, 213 aa 1>>>pF1KE1218 213 - 213 aa - 213 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2692+/-0.000887; mu= 2.6516+/- 0.054 mean_var=186.6356+/-36.475, 0's: 0 Z-trim(113.2): 27 B-trim: 7 in 2/52 Lambda= 0.093881 statistics sampled from 13800 (13817) to 13800 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.424), width: 16 Scan time: 2.410 The best scores are: opt bits E(32554) CCDS4577.1 HIST1H1C gene_id:3006|Hs108|chr6 ( 213) 1308 188.3 3e-48 CCDS4586.1 HIST1H1E gene_id:3008|Hs108|chr6 ( 219) 1106 161.0 5.3e-40 CCDS4597.1 HIST1H1D gene_id:3007|Hs108|chr6 ( 221) 1053 153.8 7.7e-38 CCDS4635.1 HIST1H1B gene_id:3009|Hs108|chr6 ( 226) 978 143.7 8.9e-35 CCDS4569.1 HIST1H1A gene_id:3024|Hs108|chr6 ( 215) 799 119.4 1.7e-27 CCDS34349.1 HIST1H1T gene_id:3010|Hs108|chr6 ( 207) 524 82.1 2.7e-16 >>CCDS4577.1 HIST1H1C gene_id:3006|Hs108|chr6 (213 aa) initn: 1308 init1: 1308 opt: 1308 Z-score: 979.7 bits: 188.3 E(32554): 3e-48 Smith-Waterman score: 1308; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213) 10 20 30 40 50 60 pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA 130 140 150 160 170 180 190 200 210 pF1KE1 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK ::::::::::::::::::::::::::::::::: CCDS45 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 190 200 210 >>CCDS4586.1 HIST1H1E gene_id:3008|Hs108|chr6 (219 aa) initn: 931 init1: 931 opt: 1106 Z-score: 831.7 bits: 161.0 E(32554): 5.3e-40 Smith-Waterman score: 1106; 86.9% identity (93.9% similar) in 214 aa overlap (1-212:1-213) 10 20 30 40 50 60 pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA ::::::::::: ::::.:::::: :.::.. :::::::::::::::::::::::::::: CCDS45 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS45 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA ::::..: :::.:::::::::.:.::::::::::::::::::::. .:: ::::::::.: CCDS45 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA 130 140 150 160 170 190 200 210 pF1KE1 KPKKAAKSAAKA--VKPKAAKPKVVKPKKAAPKKK ::::: :: ::: :::::::::..::: : ::: CCDS45 KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK 180 190 200 210 >>CCDS4597.1 HIST1H1D gene_id:3007|Hs108|chr6 (221 aa) initn: 1231 init1: 882 opt: 1053 Z-score: 792.8 bits: 153.8 E(32554): 7.7e-38 Smith-Waterman score: 1053; 81.1% identity (90.5% similar) in 222 aa overlap (1-213:1-221) 10 20 30 40 50 pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTP--RKASGPPVSELITKAVAASKERSGVS :::::: ::. ::::.:::::: ::::.: :::::::::::::::::::::::::: CCDS45 MSETAPLAPTIPAPAEKTPVKKKA-KKAGATAGKRKASGPPVSELITKAVAASKERSGVS 10 20 30 40 50 60 70 80 90 100 110 pF1KE1 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS45 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 KVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAK :.::::..::.::.::::::::.::.:::::: ::::::.::::.:. ::::::: ::.: CCDS45 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVK 120 130 140 150 160 170 180 190 200 210 pF1KE1 VAKPKKAAKSAAKA-------VKPKAAKPKVVKPKKAAPKKK . .::::::: ::: .:::..::::.: :::::::: CCDS45 TPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK 180 190 200 210 220 >>CCDS4635.1 HIST1H1B gene_id:3009|Hs108|chr6 (226 aa) initn: 737 init1: 737 opt: 978 Z-score: 737.8 bits: 143.7 E(32554): 8.9e-35 Smith-Waterman score: 978; 79.4% identity (89.9% similar) in 218 aa overlap (1-211:1-214) 10 20 30 40 50 pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT---PRKASGPPVSELITKAVAASKERSGV ::::::: :. :.::.:.::::.:::.:. :::.::::::::::::::::::.:. CCDS46 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK :::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 PKVKKAGGTKPKKPVGAA-KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKK ::.::::..: :::.::. :: :::::. ::..::::::::::::: : ::::::::: CCDS46 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPAAAGV-KKVAKSPKK 130 140 150 160 170 180 190 200 210 pF1KE1 AKVA-KPKKAAKSAAK--AVKPKAAKPKVVKPKKAAPKKK ::.: :::::.:: :: ::::::::::..::: : :: CCDS46 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 180 190 200 210 220 >>CCDS4569.1 HIST1H1A gene_id:3024|Hs108|chr6 (215 aa) initn: 585 init1: 511 opt: 799 Z-score: 607.1 bits: 119.4 E(32554): 1.7e-27 Smith-Waterman score: 799; 67.7% identity (83.4% similar) in 223 aa overlap (1-213:1-215) 10 20 30 40 50 pF1KE1 MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV ::::.: ::::. :: . ::: :: :... .: .:: :::::..:...::::.:: CCDS45 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK ::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.: CCDS45 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA : ..:.. :: : .::.:: :::.:.. :::.: :::::::::: :.: .:.::: CCDS45 PGASKVA-TKTKA-TGASKKLKKATGAS--KKSVK-TPKKAKKPAA---TRKSSKNPKKP 130 140 150 160 170 180 190 200 210 pF1KE1 KVAKPKKAAKSAAKA--VKPKAAK-----PKVVKPKKAAPKKK :..::::.::: ::: ::::::: ::..:::::::::: CCDS45 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK 180 190 200 210 >>CCDS34349.1 HIST1H1T gene_id:3010|Hs108|chr6 (207 aa) initn: 531 init1: 379 opt: 524 Z-score: 406.0 bits: 82.1 E(32554): 2.7e-16 Smith-Waterman score: 553; 52.7% identity (73.2% similar) in 220 aa overlap (1-212:1-207) 10 20 30 40 50 pF1KE1 MSETAPAAPAAAPPA--EKAPVKKKAAKKAG--GTPRKASGPPVSELITKAVAASKERSG ::::.::: :.: : :: :.::.. : :: .. ::. . ::.:::.:...:.:: : CCDS34 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA .::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::. . CCDS34 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 KPKVKKAGGTKPKKPVGA--AKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSP . :.::. ..: :: : . .:.:: : :: :.:::: :.: :...: CCDS34 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT--PKTVRSG 130 140 150 160 180 190 200 210 pF1KE1 KKAKVAKPKKAAKSA--AKAVKPKAAKPKVVKPKKAAPKKK .::: :: :. :: :.: : : .. . :. .::. :: CCDS34 RKAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK 170 180 190 200 213 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 11 16:59:36 2016 done: Fri Nov 11 16:59:36 2016 Total Scan time: 2.410 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]