Result of FASTA (ccds) for pF1KE1303
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1303, 416 aa
  1>>>pF1KE1303     416 - 416 aa - 416 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8307+/-0.000738; mu= 15.1030+/- 0.044
 mean_var=77.1391+/-15.305, 0's: 0 Z-trim(109.8): 45  B-trim: 0 in 0/51
 Lambda= 0.146028
 statistics sampled from 11132 (11175) to 11132 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.343), width:  16
 Scan time:  3.180

The best scores are:                                      opt bits E(32554)
CCDS158.1 CASP9 gene_id:842|Hs108|chr1             ( 416) 2819 603.1 1.6e-172
CCDS159.2 CASP9 gene_id:842|Hs108|chr1             ( 333) 2267 486.7 1.4e-137
CCDS59995.1 CASP9 gene_id:842|Hs108|chr1           ( 266)  918 202.5   4e-52
CCDS5879.1 CASP2 gene_id:835|Hs108|chr7            ( 452)  437 101.3   2e-21
CCDS3836.1 CASP3 gene_id:836|Hs108|chr4            ( 277)  392 91.7 9.4e-19
CCDS2343.1 CASP8 gene_id:841|Hs108|chr2            ( 464)  391 91.6 1.7e-18
CCDS2342.1 CASP8 gene_id:841|Hs108|chr2            ( 479)  391 91.6 1.7e-18
CCDS42799.1 CASP8 gene_id:841|Hs108|chr2           ( 496)  391 91.6 1.8e-18
CCDS42798.1 CASP8 gene_id:841|Hs108|chr2           ( 538)  391 91.6 1.9e-18
CCDS58096.1 CASP7 gene_id:840|Hs108|chr10          ( 278)  320 76.5 3.5e-14
CCDS7581.1 CASP7 gene_id:840|Hs108|chr10           ( 303)  320 76.5 3.8e-14
CCDS73200.1 CASP7 gene_id:840|Hs108|chr10          ( 388)  321 76.8   4e-14
CCDS7580.1 CASP7 gene_id:840|Hs108|chr10           ( 336)  320 76.6 4.1e-14
CCDS3684.1 CASP6 gene_id:839|Hs108|chr4            ( 293)  286 69.4 5.2e-12
CCDS56160.1 CASP10 gene_id:843|Hs108|chr2          ( 478)  270 66.1 8.2e-11
CCDS2339.1 CASP10 gene_id:843|Hs108|chr2           ( 479)  270 66.1 8.2e-11


>>CCDS158.1 CASP9 gene_id:842|Hs108|chr1                  (416 aa)
 initn: 2819 init1: 2819 opt: 2819  Z-score: 3210.8  bits: 603.1 E(32554): 1.6e-172
Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)

               10        20        30        40        50        60
pF1KE1 MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
              310       320       330       340       350       360

              370       380       390       400       410      
pF1KE1 SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
              370       380       390       400       410      

>>CCDS159.2 CASP9 gene_id:842|Hs108|chr1                  (333 aa)
 initn: 2267 init1: 2267 opt: 2267  Z-score: 2583.7  bits: 486.7 E(32554): 1.4e-137
Smith-Waterman score: 2267; 100.0% identity (100.0% similar) in 333 aa overlap (84-416:1-333)

            60        70        80        90       100       110   
pF1KE1 QARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRP
                                     ::::::::::::::::::::::::::::::
CCDS15                               MLASFLRTNRQAAKLSKPTLENLTPVVLRP
                                             10        20        30

           120       130       140       150       160       170   
pF1KE1 EIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 EIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCR
               40        50        60        70        80        90

           180       190       200       210       220       230   
pF1KE1 ESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 ESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVV
              100       110       120       130       140       150

           240       250       260       270       280       290   
pF1KE1 ILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 ILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKD
              160       170       180       190       200       210

           300       310       320       330       340       350   
pF1KE1 HGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 HGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVS
              220       230       240       250       260       270

           360       370       380       390       400       410   
pF1KE1 WRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS15 WRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFF
              280       290       300       310       320       330

          
pF1KE1 KTS
       :::
CCDS15 KTS
          

>>CCDS59995.1 CASP9 gene_id:842|Hs108|chr1                (266 aa)
 initn: 1774 init1: 918 opt: 918  Z-score: 1049.3  bits: 202.5 E(32554): 4e-52
Smith-Waterman score: 1478; 63.9% identity (63.9% similar) in 416 aa overlap (1-416:1-266)

               10        20        30        40        50        60
pF1KE1 MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLII
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 DLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 LRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTR
       :::::::::::::::::::                                         
CCDS59 LRPETPRPVDIGSGGFGDV-----------------------------------------
              130                                                  

              190       200       210       220       230       240
pF1KE1 TGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQ
                                                                   
CCDS59 ------------------------------------------------------------
                                                                   

              250       260       270       280       290       300
pF1KE1 ASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVAS
                                                        :::::::::::
CCDS59 -------------------------------------------------EQKDHGFEVAS
                                                      140       150

              310       320       330       340       350       360
pF1KE1 TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSG
              160       170       180       190       200       210

              370       380       390       400       410      
pF1KE1 SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 SWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
              220       230       240       250       260      

>>CCDS5879.1 CASP2 gene_id:835|Hs108|chr7                 (452 aa)
 initn: 308 init1: 200 opt: 437  Z-score: 498.1  bits: 101.3 E(32554): 2e-21
Smith-Waterman score: 548; 31.3% identity (59.0% similar) in 422 aa overlap (1-410:32-430)

                                             10        20        30
pF1KE1                               MDEADRRLLRRCRLRLVEELQVDQLWDALL
                                     :    .. :.. :. :...: ...: . ::
CCDS58 AAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLL
              10        20        30        40        50        60 

               40         50        60        70        80         
pF1KE1 SRELFRPHMIEDIQ-RAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFL
        ....  .: : :: ..:: :   :  .:.  :  :: ::.  :   :..: :  : ..:
CCDS58 EKDIITLEMRELIQAKVGSFS---QNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDML
              70        80           90       100       110        

      90       100             110        120       130        140 
pF1KE1 RTNRQAAKLSKPTLE---NLT---PVVLR-PEIRKPEVLRPETPRPVDIGSGGFG-DVGA
        :. .. .   : :    .:.   ::    :  .: ..    . . .:  .:    .:  
CCDS58 LTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKP
      120       130       140       150       160       170        

               150       160       170       180       190         
pF1KE1 L--ESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHF
          :  . . .::: :. .: :  :...::.:  :. :. :.:...:   :   :. : .
CCDS58 CTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGY
      180       190       200       210       220       230        

     200       210       220        230       240       250        
pF1KE1 MVEVKGDLTAKKMVLALLELAQQD-HGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPV
        :.:  : ::..:   : ..::   : . : :.:..:::: .       ::.::.::  .
CCDS58 DVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVE-------GAIYGVDGKLL
      240       250       260       270       280              290 

      260       270       280       290       300       310        
pF1KE1 SVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATP
       ..... ..:....:::: .:::.:::::: :.. :.: .  . . .  ::: . : ::  
CCDS58 QLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCE-ESDA--
             300       310       320       330       340           

      320       330       340       350       360       370        
pF1KE1 FQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSE
          : . . ..     ::: ::.. .:. . : .. :. : ::::.:.: ..: . : . 
CCDS58 ---GKEKLPKM----RLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDM
         350           360       370       380       390       400 

      380       390       400       410                      
pF1KE1 DLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS                
        . ..:..: ::. .:      ::  .: : :                      
CCDS58 HVADMLVKV-NAL-IKDREGYAPGT-EFHRCKEMSEYCSTLCRHLYLFPGHPPT
             410         420        430       440       450  

>>CCDS3836.1 CASP3 gene_id:836|Hs108|chr4                 (277 aa)
 initn: 509 init1: 221 opt: 392  Z-score: 450.1  bits: 91.7 E(32554): 9.4e-19
Smith-Waterman score: 514; 33.2% identity (61.3% similar) in 274 aa overlap (150-413:34-275)

     120       130       140       150       160       170         
pF1KE1 VLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRT
                                     : .: ...   : :.:::: :: . .:. .
CCDS38 TENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTS
            10        20        30        40        50        60   

     180       190       200       210       220       230         
pF1KE1 RTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGC
       :.:...:  .::. : .:.. :. :.::: ...:  . .....::.  .  : :.:::: 
CCDS38 RSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGE
            70        80        90       100       110       120   

     240       250       260       270       280       290         
pF1KE1 QASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVA
       .       : ..::.: ::...::.:.: :  : :: ::::::.:::: : . : :.:. 
CCDS38 E-------GIIFGTNG-PVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETD
                  130        140       150       160       170     

     300       310       320       330       340       350         
pF1KE1 STSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKS
       :   .:                         :  ..:. .:.. .::: ::. :::. :.
CCDS38 SGVDDDM------------------------ACHKIPVEADFLYAYSTAPGYYSWRNSKD
         180                               190       200       210 

     360       370       380       390                 400         
pF1KE1 GSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVK----------GIYKQMPGCFNFLRK
       :::....:  ...:.: . ... .: ::   :...             ::.:   ..: :
CCDS38 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTK
             220       230       240       250       260       270 

     410      
pF1KE1 KLFFKTS
       .:.:   
CCDS38 ELYFYH 
              

>>CCDS2343.1 CASP8 gene_id:841|Hs108|chr2                 (464 aa)
 initn: 394 init1: 199 opt: 391  Z-score: 445.6  bits: 91.6 E(32554): 1.7e-18
Smith-Waterman score: 486; 34.1% identity (60.9% similar) in 279 aa overlap (150-415:208-463)

     120       130       140       150       160       170         
pF1KE1 VLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFC--RES--
                                     : .: .. .: :.:::::: ::   ::.  
CCDS23 YEEFSKGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVP
       180       190       200       210       220       230       

            180       190       200       210       220        230 
pF1KE1 ---GLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQ-QDHGALDCCV
          ..: :.:...:   :   :  ::: .. . : :... .  .:.. : .::. .:: .
CCDS23 KLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQ-IYEILKIYQLMDHSNMDCFI
       240       250       260       270        280       290      

             240       250       260       270       280       290 
pF1KE1 VVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQ
         ::::: .       : .:::::  . . .... :.: .::::.::::.:::::: :..
CCDS23 CCILSHGDK-------GIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDN
        300              310       320       330       340         

             300       310       320       330       340       350 
pF1KE1 KDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGF
        ..:. : . : :.            :. :   .  :   :   :  .:......:  . 
CCDS23 YQKGIPVETDSEEQ------------PYLEMDLSSPQTRYI---PDEADFLLGMATVNNC
     350       360                   370          380       390    

             360        370       380       390           400      
pF1KE1 VSWRDPKSGSWYVETL-DDIFEQWAHSEDLQSLLLRVANAVSVK----GIYKQMPGCFNF
       ::.:.:  :.::...: ... :.  ...:. ..: .:   :: :    .. ::::     
CCDS23 VSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFT
          400       410       420       430       440       450    

        410      
pF1KE1 LRKKLFFKTS
       ::::: : . 
CCDS23 LRKKLVFPSD
          460    

>>CCDS2342.1 CASP8 gene_id:841|Hs108|chr2                 (479 aa)
 initn: 394 init1: 199 opt: 391  Z-score: 445.4  bits: 91.6 E(32554): 1.7e-18
Smith-Waterman score: 486; 34.1% identity (60.9% similar) in 279 aa overlap (150-415:223-478)

     120       130       140       150       160       170         
pF1KE1 VLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFC--RES--
                                     : .: .. .: :.:::::: ::   ::.  
CCDS23 PDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVP
            200       210       220       230       240       250  

            180       190       200       210       220        230 
pF1KE1 ---GLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQ-QDHGALDCCV
          ..: :.:...:   :   :  ::: .. . : :... .  .:.. : .::. .:: .
CCDS23 KLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQ-IYEILKIYQLMDHSNMDCFI
            260       270       280       290        300       310 

             240       250       260       270       280       290 
pF1KE1 VVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQ
         ::::: .       : .:::::  . . .... :.: .::::.::::.:::::: :..
CCDS23 CCILSHGDK-------GIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDN
             320              330       340       350       360    

             300       310       320       330       340       350 
pF1KE1 KDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGF
        ..:. : . : :.            :. :   .  :   :   :  .:......:  . 
CCDS23 YQKGIPVETDSEEQ------------PYLEMDLSSPQTRYI---PDEADFLLGMATVNNC
          370                   380       390          400         

             360        370       380       390           400      
pF1KE1 VSWRDPKSGSWYVETL-DDIFEQWAHSEDLQSLLLRVANAVSVK----GIYKQMPGCFNF
       ::.:.:  :.::...: ... :.  ...:. ..: .:   :: :    .. ::::     
CCDS23 VSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFT
     410       420       430       440       450       460         

        410      
pF1KE1 LRKKLFFKTS
       ::::: : . 
CCDS23 LRKKLVFPSD
     470         

>>CCDS42799.1 CASP8 gene_id:841|Hs108|chr2                (496 aa)
 initn: 394 init1: 199 opt: 391  Z-score: 445.1  bits: 91.6 E(32554): 1.8e-18
Smith-Waterman score: 486; 34.1% identity (60.9% similar) in 279 aa overlap (150-415:240-495)

     120       130       140       150       160       170         
pF1KE1 VLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFC--RES--
                                     : .: .. .: :.:::::: ::   ::.  
CCDS42 YEEFSKGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVP
     210       220       230       240       250       260         

            180       190       200       210       220        230 
pF1KE1 ---GLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQ-QDHGALDCCV
          ..: :.:...:   :   :  ::: .. . : :... .  .:.. : .::. .:: .
CCDS42 KLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQ-IYEILKIYQLMDHSNMDCFI
     270       280       290       300        310       320        

             240       250       260       270       280       290 
pF1KE1 VVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQ
         ::::: .       : .:::::  . . .... :.: .::::.::::.:::::: :..
CCDS42 CCILSHGDK-------GIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDN
      330              340       350       360       370       380 

             300       310       320       330       340       350 
pF1KE1 KDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGF
        ..:. : . : :.            :. :   .  :   :   :  .:......:  . 
CCDS42 YQKGIPVETDSEEQ------------PYLEMDLSSPQTRYI---PDEADFLLGMATVNNC
             390                   400       410          420      

             360        370       380       390           400      
pF1KE1 VSWRDPKSGSWYVETL-DDIFEQWAHSEDLQSLLLRVANAVSVK----GIYKQMPGCFNF
       ::.:.:  :.::...: ... :.  ...:. ..: .:   :: :    .. ::::     
CCDS42 VSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFT
        430       440       450       460       470       480      

        410      
pF1KE1 LRKKLFFKTS
       ::::: : . 
CCDS42 LRKKLVFPSD
        490      

>>CCDS42798.1 CASP8 gene_id:841|Hs108|chr2                (538 aa)
 initn: 394 init1: 199 opt: 391  Z-score: 444.6  bits: 91.6 E(32554): 1.9e-18
Smith-Waterman score: 486; 34.1% identity (60.9% similar) in 279 aa overlap (150-415:282-537)

     120       130       140       150       160       170         
pF1KE1 VLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFC--RES--
                                     : .: .. .: :.:::::: ::   ::.  
CCDS42 PDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVP
             260       270       280       290       300       310 

            180       190       200       210       220        230 
pF1KE1 ---GLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQ-QDHGALDCCV
          ..: :.:...:   :   :  ::: .. . : :... .  .:.. : .::. .:: .
CCDS42 KLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQ-IYEILKIYQLMDHSNMDCFI
             320       330       340       350        360       370

             240       250       260       270       280       290 
pF1KE1 VVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQ
         ::::: .       : .:::::  . . .... :.: .::::.::::.:::::: :..
CCDS42 CCILSHGDK-------GIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDN
                     380       390       400       410       420   

             300       310       320       330       340       350 
pF1KE1 KDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGF
        ..:. : . : :.            :. :   .  :   :   :  .:......:  . 
CCDS42 YQKGIPVETDSEEQ------------PYLEMDLSSPQTRYI---PDEADFLLGMATVNNC
           430                   440       450          460        

             360        370       380       390           400      
pF1KE1 VSWRDPKSGSWYVETL-DDIFEQWAHSEDLQSLLLRVANAVSVK----GIYKQMPGCFNF
       ::.:.:  :.::...: ... :.  ...:. ..: .:   :: :    .. ::::     
CCDS42 VSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFT
      470       480       490       500       510       520        

        410      
pF1KE1 LRKKLFFKTS
       ::::: : . 
CCDS42 LRKKLVFPSD
      530        

>>CCDS58096.1 CASP7 gene_id:840|Hs108|chr10               (278 aa)
 initn: 438 init1: 200 opt: 320  Z-score: 368.1  bits: 76.5 E(32554): 3.5e-14
Smith-Waterman score: 458; 33.3% identity (59.0% similar) in 273 aa overlap (153-413:35-276)

            130       140       150       160       170       180  
pF1KE1 PETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTG
                                     : ...:  :.:.:::: :: . .:. .:.:
CCDS58 LFSDGDTSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG
           10        20        30        40        50        60    

            190       200       210       220       230       240  
pF1KE1 SNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQAS
       .. : : : . : :: : : : .: .  ::   : . ...::    : . ..:::: .  
CCDS58 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEE--
           70        80        90       100       110       120    

            250       260       270       280       290       300  
pF1KE1 HLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTS
            ...:: ::  . .. ..  : :  : .:  :::::::::: : . : :.. :...
CCDS58 -----NVIYGKDGV-TPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQ-ADSG
                 130        140       150       160       170      

            310       320       330       340       350       360  
pF1KE1 PEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSW
       : ...       ::.:  .             .:. .:.. .::: ::. :::.:  :::
CCDS58 PINDT-------DANPRYK-------------IPVEADFLFAYSTVPGYYSWRSPGRGSW
         180                           190       200       210     

            370       380         390                 400       410
pF1KE1 YVETLDDIFEQWAHSEDLQ--SLLLRVANAVSVK----------GIYKQMPGCFNFLRKK
       .:..: .:.:.  :..::.  ..: :: . :. .             ::.:   ..: :.
CCDS58 FVQALCSILEE--HGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKE
         220         230       240       250       260       270   

             
pF1KE1 LFFKTS
       :.:   
CCDS58 LYFSQ 
             




416 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon May 22 10:33:28 2017 done: Mon May 22 10:33:29 2017
 Total Scan time:  3.180 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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