FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1345, 264 aa
  1>>>pF1KE1345 264 - 264 aa - 264 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9031+/-0.000732; mu= 17.9393+/- 0.044
 mean_var=76.1030+/-15.036, 0's: 0 Z-trim(109.7): 13  B-trim: 0 in 0/53
 Lambda= 0.147019
 statistics sampled from 11065 (11074) to 11065 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.34), width:  16
 Scan time:  2.580

The best scores are:                                      opt bits E(32554)
CCDS8368.1 NNMT gene_id:4837|Hs108|chr11           ( 264) 1759 382.0 2.4e-106
CCDS5430.1 INMT gene_id:11185|Hs108|chr7           ( 263)  894 198.5   4e-51
CCDS56479.1 INMT gene_id:11185|Hs108|chr7          ( 262)  886 196.8 1.3e-50
CCDS11343.1 PNMT gene_id:5409|Hs108|chr17          ( 282)  592 134.5 8.1e-32


>>CCDS8368.1 NNMT gene_id:4837|Hs108|chr11                (264 aa)
 initn: 1759 init1: 1759 opt: 1759  Z-score: 2022.8  bits: 382.0 E(32554): 2.4e-106
Smith-Waterman score: 1759; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)

               10        20        30        40        50        60
pF1KE1 MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS83 RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
              190       200       210       220       230       240

              250       260    
pF1KE1 SYSSTMANNEGLFSLVARKLSRPL
       ::::::::::::::::::::::::
CCDS83 SYSSTMANNEGLFSLVARKLSRPL
              250       260    

>>CCDS5430.1 INMT gene_id:11185|Hs108|chr7                (263 aa)
 initn: 891 init1: 891 opt: 894  Z-score: 1031.3  bits: 198.5 E(32554): 4e-51
Smith-Waterman score: 894; 53.2% identity (74.5% similar) in 263 aa overlap (1-263:1-263)

               10        20        30        40        50        60
pF1KE1 MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
       :..:::. : : .:: :::::  ::.: .  : :...::  :. : : :   :..:: ::
CCDS54 MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
       ::::::::::.:.::.::..:...:..:.: .:::::::::: :.::.:.: ..:.::::
CCDS54 DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
         .  ::::::: :::.::::::  ..::. . :: :::::. : .. :: .: .:  ::
CCDS54 SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
        ::.::::::: ::   .:.   ::.:...:: . : .: :: :: .::. :: .    :
CCDS54 CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ
              190       200       210       220       230       240

              250       260    
pF1KE1 SYSSTMANNEGLFSLVARKLSRPL
       ::: : : :.:.  .::::   : 
CCDS54 SYSVTNAANNGVCFIVARKKPGP 
              250       260    

>>CCDS56479.1 INMT gene_id:11185|Hs108|chr7               (262 aa)
 initn: 885 init1: 747 opt: 886  Z-score: 1022.2  bits: 196.8 E(32554): 1.3e-50
Smith-Waterman score: 886; 53.2% identity (74.5% similar) in 263 aa overlap (1-263:1-262)

               10        20        30        40        50        60
pF1KE1 MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
       :..:::. : : .:: :::::  ::.: .  : :...::  :. : : :   :..:: ::
CCDS56 MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFG-PGLQGDTLI
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KE1 DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
       ::::::::::.:.::.::..:...:..:.: .:::::::::: :.::.:.: ..:.::::
CCDS56 DIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGN
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE1 RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
         .  ::::::: :::.::::::  ..::. . :: :::::. : .. :: .: .:  ::
CCDS56 SGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAAL
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KE1 RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
        ::.::::::: ::   .:.   ::.:...:: . : .: :: :: .::. :: .    :
CCDS56 CNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQ
     180       190       200       210       220       230         

              250       260    
pF1KE1 SYSSTMANNEGLFSLVARKLSRPL
       ::: : : :.:.  .::::   : 
CCDS56 SYSVTNAANNGVCFIVARKKPGP 
     240       250       260   

>>CCDS11343.1 PNMT gene_id:5409|Hs108|chr17               (282 aa)
 initn: 583 init1: 345 opt: 592  Z-score: 684.7  bits: 134.5 E(32554): 8.1e-32
Smith-Waterman score: 592; 39.7% identity (67.9% similar) in 252 aa overlap (15-260:30-280)

                              10        20        30          40   
pF1KE1                MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHS--AESQILKHLLK
                                    :.:: ::.. :    : .    . .    :.
CCDS11 MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYA-PPRGDLCNPNGVGPWKLR
               10        20        30        40         50         

            50        60        70        80        90       100   
pF1KE1 NLFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPE
        : . :    :.:  :::::::::.:::::::  :..:..::. . : ::: .::..:: 
CCDS11 CLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPG
      60        70        80        90       100       110         

           110       120       130       140       150         160 
pF1KE1 AFDWSPVVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGA-VPLP-PADCVL
       ::.::    ..: .::.     .::..::  ::.::  :: : :::::  : : ::: ..
CCDS11 AFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALV
     120       130       140       150       160       170         

             170       180       190       200       210       220 
pF1KE1 STLCLDAACPDLPTYCRALRNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAV
       :..::.:. ::: .. ::: .. .::.::: :... ::. :.:. :: ... .:...: :
CCDS11 SAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEV
     180       190       200       210       220       230         

             230         240       250       260    
pF1KE1 EAAVKEAGYTIEWFE--VISQSYSSTMANNEGLFSLVARKLSRPL
       . :. ..:: .. ..  ..    .. . . .:.:   :.:.    
CCDS11 REALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL  
     240       250       260       270       280    




264 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 23:37:45 2016 done: Sun Nov  6 23:37:45 2016
 Total Scan time:  2.580 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]