FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1351, 637 aa 1>>>pF1KE1351 637 - 637 aa - 637 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3143+/-0.000385; mu= 19.0354+/- 0.024 mean_var=68.6687+/-13.695, 0's: 0 Z-trim(112.2): 51 B-trim: 0 in 0/53 Lambda= 0.154773 statistics sampled from 21061 (21097) to 21061 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.247), width: 16 Scan time: 9.490 The best scores are: opt bits E(85289) NP_006100 (OMIM: 604045) protein arginine N-methyl ( 637) 4369 985.1 0 NP_001034708 (OMIM: 604045) protein arginine N-met ( 620) 4151 936.4 0 NP_001269883 (OMIM: 604045) protein arginine N-met ( 531) 3644 823.2 0 XP_016876416 (OMIM: 604045) PREDICTED: protein arg ( 531) 3644 823.2 0 NP_001269882 (OMIM: 604045) protein arginine N-met ( 576) 3553 802.9 0 NP_001269884 (OMIM: 604045) protein arginine N-met ( 593) 3553 802.9 0 NP_001269885 (OMIM: 604045) protein arginine N-met ( 466) 2597 589.4 9.7e-168 XP_011525940 (OMIM: 603934) PREDICTED: histone-arg ( 447) 156 44.3 0.0011 XP_005259765 (OMIM: 603934) PREDICTED: histone-arg ( 585) 156 44.4 0.0014 NP_954592 (OMIM: 603934) histone-arginine methyltr ( 608) 156 44.4 0.0014 NP_001229795 (OMIM: 601961) protein arginine N-met ( 277) 142 41.1 0.0066 NP_001273606 (OMIM: 601961) protein arginine N-met ( 289) 142 41.1 0.0068 NP_996845 (OMIM: 601961) protein arginine N-methyl ( 433) 142 41.2 0.0095 XP_005261168 (OMIM: 601961) PREDICTED: protein arg ( 433) 142 41.2 0.0095 NP_001526 (OMIM: 601961) protein arginine N-methyl ( 433) 142 41.2 0.0095 >>NP_006100 (OMIM: 604045) protein arginine N-methyltran (637 aa) initn: 4369 init1: 4369 opt: 4369 Z-score: 5268.8 bits: 985.1 E(85289): 0 Smith-Waterman score: 4369; 100.0% identity (100.0% similar) in 637 aa overlap (1-637:1-637) 10 20 30 40 50 60 pF1KE1 MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 AFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 GEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 KGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDM 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 REWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 REWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 YNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 PVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICV 550 560 570 580 590 600 610 620 630 pF1KE1 RFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::::::::::::::::::: NP_006 RFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 610 620 630 >>NP_001034708 (OMIM: 604045) protein arginine N-methylt (620 aa) initn: 4151 init1: 4151 opt: 4151 Z-score: 5005.9 bits: 936.4 E(85289): 0 Smith-Waterman score: 4151; 100.0% identity (100.0% similar) in 603 aa overlap (35-637:18-620) 10 20 30 40 50 60 pF1KE1 AVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPG :::::::::::::::::::::::::::::: NP_001 MRGPNSGTEKGRLVIPEKQGFDFLCMPVFHPRFKREFIQEPAKNRPG 10 20 30 40 70 80 90 100 110 120 pF1KE1 PQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 PLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 TWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFP 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 VLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE1 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE1 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE1 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE1 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR 530 540 550 560 570 580 610 620 630 pF1KE1 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::::::::::::::: NP_001 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 590 600 610 620 >>NP_001269883 (OMIM: 604045) protein arginine N-methylt (531 aa) initn: 3644 init1: 3644 opt: 3644 Z-score: 4395.1 bits: 823.2 E(85289): 0 Smith-Waterman score: 3644; 100.0% identity (100.0% similar) in 531 aa overlap (107-637:1-531) 80 90 100 110 120 130 pF1KE1 DWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLAR :::::::::::::::::::::::::::::: NP_001 MLQELNFGAYLGLPAFLLPLNQEDNTNLAR 10 20 30 140 150 160 170 180 190 pF1KE1 VLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLC 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE1 DYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE1 LLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLM 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE1 DNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE1 RAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSEL 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE1 LGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEA 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE1 QFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFE 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE1 TVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWA 460 470 480 490 500 510 620 630 pF1KE1 VTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::: NP_001 VTAPVCSAIHNPTGRSYTIGL 520 530 >>XP_016876416 (OMIM: 604045) PREDICTED: protein arginin (531 aa) initn: 3644 init1: 3644 opt: 3644 Z-score: 4395.1 bits: 823.2 E(85289): 0 Smith-Waterman score: 3644; 100.0% identity (100.0% similar) in 531 aa overlap (107-637:1-531) 80 90 100 110 120 130 pF1KE1 DWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDNTNLAR :::::::::::::::::::::::::::::: XP_016 MLQELNFGAYLGLPAFLLPLNQEDNTNLAR 10 20 30 140 150 160 170 180 190 pF1KE1 VLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEKTWMWWHNFRTLC 40 50 60 70 80 90 200 210 220 230 240 250 pF1KE1 DYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMHQRLIFR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KE1 LLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLM 160 170 180 190 200 210 320 330 340 350 360 370 pF1KE1 DNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASL 220 230 240 250 260 270 380 390 400 410 420 430 pF1KE1 RAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKADIIVSEL 280 290 300 310 320 330 440 450 460 470 480 490 pF1KE1 LGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREKDRDPEA 340 350 360 370 380 390 500 510 520 530 540 550 pF1KE1 QFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFE 400 410 420 430 440 450 560 570 580 590 600 610 pF1KE1 TVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWA 460 470 480 490 500 510 620 630 pF1KE1 VTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::: XP_016 VTAPVCSAIHNPTGRSYTIGL 520 530 >>NP_001269882 (OMIM: 604045) protein arginine N-methylt (576 aa) initn: 3839 init1: 3550 opt: 3553 Z-score: 4284.8 bits: 802.9 E(85289): 0 Smith-Waterman score: 3755; 92.7% identity (92.7% similar) in 603 aa overlap (35-637:18-576) 10 20 30 40 50 60 pF1KE1 AVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPG :::::::::::::::::::::::::::::: NP_001 MRGPNSGTEKGRLVIPEKQGFDFLCMPVFHPRFKREFIQEPAKNRPG 10 20 30 40 70 80 90 100 110 120 pF1KE1 PQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLL :::::::::::: :::: NP_001 PQTRSDLLLSGR--------------------------------------------AFLL 50 60 130 140 150 160 170 180 pF1KE1 PLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEK 70 80 90 100 110 120 190 200 210 220 230 240 pF1KE1 TWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFP 130 140 150 160 170 180 250 260 270 280 290 300 pF1KE1 VLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY 190 200 210 220 230 240 310 320 330 340 350 360 pF1KE1 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL 250 260 270 280 290 300 370 380 390 400 410 420 pF1KE1 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV 310 320 330 340 350 360 430 440 450 460 470 480 pF1KE1 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV 370 380 390 400 410 420 490 500 510 520 530 540 pF1KE1 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV 430 440 450 460 470 480 550 560 570 580 590 600 pF1KE1 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR 490 500 510 520 530 540 610 620 630 pF1KE1 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::::::::::::::: NP_001 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 550 560 570 >>NP_001269884 (OMIM: 604045) protein arginine N-methylt (593 aa) initn: 4057 init1: 3550 opt: 3553 Z-score: 4284.6 bits: 802.9 E(85289): 0 Smith-Waterman score: 3973; 93.1% identity (93.1% similar) in 637 aa overlap (1-637:1-593) 10 20 30 40 50 60 pF1KE1 MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAAMAVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 NRPGPQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLP :::::::::::::::: NP_001 NRPGPQTRSDLLLSGR-------------------------------------------- 70 130 140 150 160 170 180 pF1KE1 AFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFLLPLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYS 80 90 100 110 120 130 190 200 210 220 230 240 pF1KE1 GEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEEKTWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNK 140 150 160 170 180 190 250 260 270 280 290 300 pF1KE1 KGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGFPVLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELF 200 210 220 230 240 250 310 320 330 340 350 360 pF1KE1 AKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQV 260 270 280 290 300 310 370 380 390 400 410 420 pF1KE1 LMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDM 320 330 340 350 360 370 430 440 450 460 470 480 pF1KE1 REWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKL 380 390 400 410 420 430 490 500 510 520 530 540 pF1KE1 YNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEF 440 450 460 470 480 490 550 560 570 580 590 600 pF1KE1 PVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICV 500 510 520 530 540 550 610 620 630 pF1KE1 RFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::::::::::::::::::: NP_001 RFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 560 570 580 590 >>NP_001269885 (OMIM: 604045) protein arginine N-methylt (466 aa) initn: 2597 init1: 2597 opt: 2597 Z-score: 3132.5 bits: 589.4 E(85289): 9.7e-168 Smith-Waterman score: 2781; 74.5% identity (74.5% similar) in 603 aa overlap (35-637:18-466) 10 20 30 40 50 60 pF1KE1 AVGGAGGSRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPG :::::::::::::::::::::::::::::: NP_001 MRGPNSGTEKGRLVIPEKQGFDFLCMPVFHPRFKREFIQEPAKNRPG 10 20 30 40 70 80 90 100 110 120 pF1KE1 PQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLL ::::::::::::::::::::::::::::::::::::::::: NP_001 PQTRSDLLLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEA------------------- 50 60 70 80 130 140 150 160 170 180 pF1KE1 PLNQEDNTNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEEYSGEEK NP_001 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KE1 TWMWWHNFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFP NP_001 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KE1 VLSKMHQRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY ::::::::::::::::::::::::::::::::::::::::::::: NP_001 ---------------LEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGY 90 100 110 120 130 310 320 330 340 350 360 pF1KE1 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVL 140 150 160 170 180 190 370 380 390 400 410 420 pF1KE1 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWV 200 210 220 230 240 250 430 440 450 460 470 480 pF1KE1 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV 260 270 280 290 300 310 490 500 510 520 530 540 pF1KE1 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEV 320 330 340 350 360 370 550 560 570 580 590 600 pF1KE1 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWR 380 390 400 410 420 430 610 620 630 pF1KE1 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ::::::::::::::::::::::::::::::::: NP_001 CSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL 440 450 460 >>XP_011525940 (OMIM: 603934) PREDICTED: histone-arginin (447 aa) initn: 133 init1: 133 opt: 156 Z-score: 187.0 bits: 44.3 E(85289): 0.0011 Smith-Waterman score: 181; 23.3% identity (51.1% similar) in 309 aa overlap (329-621:3-295) 300 310 320 330 340 350 pF1KE1 LFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNV .: .. . ::.:: . : :: XP_011 MMQDYVRTGTYQRAILQNHTDF-----KD--- 10 20 360 370 380 390 400 410 pF1KE1 QVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSS .... .: : : : :. :: :: : :.:::: . : . . .. ....:. . XP_011 KIVLDVGCGSGIL---SFFAA-QAGAR-KIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG 30 40 50 60 70 420 430 440 450 460 470 pF1KE1 DMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSS ..: ::..:::.:: .: . :: : :...:: .: .: :::... XP_011 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE 80 90 100 110 120 130 480 490 500 510 520 pF1KE1 KLYNE---------------VRACREKDRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSH .:: : : . . :..: :: ... : : . .: . XP_011 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQP-VVDTFDIRILMAKSVKYTVNF 140 150 160 170 180 190 530 540 550 560 570 580 pF1KE1 PNRDPMIDNNRY-CTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPI . : .: ..: . . ..::.: .:.... .: . . . :. . XP_011 LEAKEG-DLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQV 200 210 220 230 240 250 590 600 610 620 630 pF1KE1 LFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGRSYTIGL ...:. .. :.:. .:... :. ...: : XP_011 RCLFQSPLFAKAGDTLSGTCLLIANKRQS-YDISIVAQVDQTGSKSSNLLDLKNPFFRYT 260 270 280 290 300 310 XP_011 GTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIP 320 330 340 350 360 370 >>XP_005259765 (OMIM: 603934) PREDICTED: histone-arginin (585 aa) initn: 167 init1: 133 opt: 156 Z-score: 185.3 bits: 44.4 E(85289): 0.0014 Smith-Waterman score: 187; 22.9% identity (49.5% similar) in 380 aa overlap (264-621:98-456) 240 250 260 270 280 pF1KE1 SIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIIT-GTNH-----HSEKEFCSYLQYLEYL :::: : : . ..:::. . :. XP_005 GIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILK-- 70 80 90 100 110 120 290 300 310 320 330 340 pF1KE1 SQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLD : .:.. :. .. : .: . . .: .. . ::.:: . : XP_005 -TCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQ--QNMMQDYVRTGTYQRAILQNHTD 130 140 150 160 170 180 350 360 370 380 390 400 pF1KE1 RVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFE :: .... .: : : : :. :: :: : :.:::: . : . . . XP_005 -----FKD---KIVLDVGCGSGIL---SFFAA-QAGAR-KIYAVEASTMAQHAEVLVKSN 190 200 210 220 410 420 430 440 450 460 pF1KE1 EWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGE . ....:. . ..: ::..:::.:: .: . :: : :...:: .: .: XP_005 NLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTI 230 240 250 260 270 280 470 480 490 500 510 pF1KE1 YTSFLAPISSSKLYNE---------------VRACREKDRDPEAQFEMPYVVRLHNFHQL :::... .:: : : . . :..: :: ... : XP_005 GDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQP-VVDTFDIRIL 290 300 310 320 330 340 520 530 540 550 560 570 pF1KE1 SAPQPCFTFSHPNRDPMIDNNRY-CTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPET : . .: . . : .: ..: . . ..::.: .:.... .: . XP_005 MAKSVKYTVNFLEAKEG-DLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTA 350 360 370 380 390 400 580 590 600 610 620 630 pF1KE1 HSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGR . . :. . ...:. .. :.:. .:... :. ...: : XP_005 PTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQS-YDISIVAQVDQTGSKSSNL 410 420 430 440 450 460 pF1KE1 SYTIGL XP_005 LDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAS 470 480 490 500 510 520 >>NP_954592 (OMIM: 603934) histone-arginine methyltransf (608 aa) initn: 167 init1: 133 opt: 156 Z-score: 185.1 bits: 44.4 E(85289): 0.0014 Smith-Waterman score: 187; 22.9% identity (49.5% similar) in 380 aa overlap (264-621:98-456) 240 250 260 270 280 pF1KE1 SIFLTNKKGFPVLSKMHQRLIFRLLKLEVQFIIT-GTNH-----HSEKEFCSYLQYLEYL :::: : : . ..:::. . :. NP_954 GIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILK-- 70 80 90 100 110 120 290 300 310 320 330 340 pF1KE1 SQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLD : .:.. :. .. : .: . . .: .. . ::.:: . : NP_954 -TCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQ--QNMMQDYVRTGTYQRAILQNHTD 130 140 150 160 170 180 350 360 370 380 390 400 pF1KE1 RVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFE :: .... .: : : : :. :: :: : :.:::: . : . . . NP_954 -----FKD---KIVLDVGCGSGIL---SFFAA-QAGAR-KIYAVEASTMAQHAEVLVKSN 190 200 210 220 410 420 430 440 450 460 pF1KE1 EWGSQVTVVSSDMREWVAPEKADIIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGE . ....:. . ..: ::..:::.:: .: . :: : :...:: .: .: NP_954 NLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTI 230 240 250 260 270 280 470 480 490 500 510 pF1KE1 YTSFLAPISSSKLYNE---------------VRACREKDRDPEAQFEMPYVVRLHNFHQL :::... .:: : : . . :..: :: ... : NP_954 GDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQP-VVDTFDIRIL 290 300 310 320 330 340 520 530 540 550 560 570 pF1KE1 SAPQPCFTFSHPNRDPMIDNNRY-CTLEFPVEVNTVLHGFAGYFETVLYQDITLSIRPET : . .: . . : .: ..: . . ..::.: .:.... .: . NP_954 MAKSVKYTVNFLEAKEG-DLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTA 350 360 370 380 390 400 580 590 600 610 620 630 pF1KE1 HSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKKVWYEWAVTAPVCSAIHNPTGR . . :. . ...:. .. :.:. .:... :. ...: : NP_954 PTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQS-YDISIVAQVDQTGSKSSNL 410 420 430 440 450 460 pF1KE1 SYTIGL NP_954 LDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIAS 470 480 490 500 510 520 637 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 00:31:54 2016 done: Mon Nov 7 00:31:55 2016 Total Scan time: 9.490 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]