Result of FASTA (omim) for pF1KE1394
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1394, 522 aa
  1>>>pF1KE1394 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4636+/-0.00038; mu= 15.5223+/- 0.024
 mean_var=153.9286+/-31.391, 0's: 0 Z-trim(117.8): 25  B-trim: 320 in 2/53
 Lambda= 0.103375
 statistics sampled from 30085 (30108) to 30085 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.353), width:  16
 Scan time: 10.410

The best scores are:                                      opt bits E(85289)
NP_001192183 (OMIM: 251290,602876) occludin isofor ( 522) 3526 537.9 2.8e-152
NP_002529 (OMIM: 251290,602876) occludin isoform a ( 522) 3526 537.9 2.8e-152
NP_001192184 (OMIM: 251290,602876) occludin isofor ( 271) 1822 283.5 5.6e-76
XP_016864402 (OMIM: 251290,602876) PREDICTED: occl ( 468) 1685 263.3 1.2e-69
XP_016864403 (OMIM: 251290,602876) PREDICTED: occl ( 468) 1685 263.3 1.2e-69
XP_016882826 (OMIM: 600284) PREDICTED: RNA polymer ( 337)  247 48.7 3.3e-05
XP_016882825 (OMIM: 600284) PREDICTED: RNA polymer ( 370)  247 48.7 3.6e-05
XP_016882824 (OMIM: 600284) PREDICTED: RNA polymer ( 488)  247 48.8 4.3e-05
NP_006523 (OMIM: 600284) RNA polymerase II elongat ( 621)  247 49.0   5e-05
XP_016864732 (OMIM: 601874) PREDICTED: RNA polymer ( 455)  232 46.6 0.00019
XP_016864729 (OMIM: 601874) PREDICTED: RNA polymer ( 508)  232 46.6 0.00021
XP_016864730 (OMIM: 601874) PREDICTED: RNA polymer ( 508)  232 46.6 0.00021
XP_016864731 (OMIM: 601874) PREDICTED: RNA polymer ( 508)  232 46.6 0.00021
XP_006714638 (OMIM: 601874) PREDICTED: RNA polymer ( 585)  232 46.7 0.00023
NP_036213 (OMIM: 601874) RNA polymerase II elongat ( 640)  232 46.7 0.00024
XP_005248504 (OMIM: 610153,610572) PREDICTED: MARV ( 546)  213 43.8  0.0016
NP_001231663 (OMIM: 610153,610572) MARVEL domain-c ( 546)  213 43.8  0.0016
XP_005248502 (OMIM: 610153,610572) PREDICTED: MARV ( 558)  213 43.8  0.0016
XP_005248503 (OMIM: 610153,610572) PREDICTED: MARV ( 558)  213 43.8  0.0016
NP_001033692 (OMIM: 610153,610572) MARVEL domain-c ( 558)  213 43.8  0.0016


>>NP_001192183 (OMIM: 251290,602876) occludin isoform a   (522 aa)
 initn: 3526 init1: 3526 opt: 3526  Z-score: 2855.0  bits: 537.9 E(85289): 2.8e-152
Smith-Waterman score: 3526; 99.8% identity (99.8% similar) in 522 aa overlap (1-522:1-522)

               10        20        30        40        50        60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
              430       440       450       460       470       480

              490       500       510       520  
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
              490       500       510       520  

>>NP_002529 (OMIM: 251290,602876) occludin isoform a [Ho  (522 aa)
 initn: 3526 init1: 3526 opt: 3526  Z-score: 2855.0  bits: 537.9 E(85289): 2.8e-152
Smith-Waterman score: 3526; 99.8% identity (99.8% similar) in 522 aa overlap (1-522:1-522)

               10        20        30        40        50        60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_002 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
              430       440       450       460       470       480

              490       500       510       520  
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
       ::::::::::::::::::::::::::::::::::::::::::
NP_002 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
              490       500       510       520  

>>NP_001192184 (OMIM: 251290,602876) occludin isoform b   (271 aa)
 initn: 1822 init1: 1822 opt: 1822  Z-score: 1485.0  bits: 283.5 E(85289): 5.6e-76
Smith-Waterman score: 1822; 100.0% identity (100.0% similar) in 271 aa overlap (252-522:1-271)

             230       240       250       260       270       280 
pF1KE1 PAATGLYVDQYSYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILW
                                     ::::::::::::::::::::::::::::::
NP_001                               MIIVAFALIIFFAVKTRRKMDRYDKSNILW
                                             10        20        30

             290       300       310       320       330       340 
pF1KE1 DKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESS
               40        50        60        70        80        90

             350       360       370       380       390       400 
pF1KE1 YKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETD
              100       110       120       130       140       150

             410       420       430       440       450       460 
pF1KE1 YTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLD
              160       170       180       190       200       210

             470       480       490       500       510       520 
pF1KE1 KELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQK
              220       230       240       250       260       270

        
pF1KE1 T
       :
NP_001 T
        

>>XP_016864402 (OMIM: 251290,602876) PREDICTED: occludin  (468 aa)
 initn: 1662 init1: 1662 opt: 1685  Z-score: 1371.7  bits: 263.3 E(85289): 1.2e-69
Smith-Waterman score: 3046; 89.5% identity (89.5% similar) in 522 aa overlap (1-522:1-468)

               10        20        30        40        50        60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
       :::                                                      :::
XP_016 PQE------------------------------------------------------VKN
                                                                   

              310       320       330       340       350       360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
        250       260       270       280       290       300      

              370       380       390       400       410       420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
        310       320       330       340       350       360      

              430       440       450       460       470       480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
        370       380       390       400       410       420      

              490       500       510       520  
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
        430       440       450       460        

>>XP_016864403 (OMIM: 251290,602876) PREDICTED: occludin  (468 aa)
 initn: 1662 init1: 1662 opt: 1685  Z-score: 1371.7  bits: 263.3 E(85289): 1.2e-69
Smith-Waterman score: 3046; 89.5% identity (89.5% similar) in 522 aa overlap (1-522:1-468)

               10        20        30        40        50        60
pF1KE1 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVD
       :::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 ILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE1 PQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKN
       :::                                                      :::
XP_016 PQE------------------------------------------------------VKN
                                                                   

              310       320       330       340       350       360
pF1KE1 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPV
        250       260       270       280       290       300      

              370       380       390       400       410       420
pF1KE1 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREY
        310       320       330       340       350       360      

              430       440       450       460       470       480
pF1KE1 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADE
        370       380       390       400       410       420      

              490       500       510       520  
pF1KE1 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
        430       440       450       460        

>>XP_016882826 (OMIM: 600284) PREDICTED: RNA polymerase   (337 aa)
 initn: 255 init1: 148 opt: 247  Z-score: 214.4  bits: 48.7 E(85289): 3.3e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:101-332)

              290       300       310       320       330       340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
                                     ::     :. .:.:  ::   .. :   : 
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
               80        90       100       110       120          

              350       360        370       380       390         
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
       .  ..:.: :   ::: .   .  .:. : : .. .  ::.   : ::...:   :  : 
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
     130       140       150       160       170       180         

       400       410                        420       430       440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
         . ..: :   :                     :.. .:  :.:..::: :: .:..  
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
     190       200       210       220       230       240         

              450       460       470           480       490      
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
       .::..:......:......:: .: .  . :::: ..     .:: ..:  : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
     250       260       270       280       290         300       

        500       510       520      
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT    
       :..:. :.:::.:::.....::...     
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
       310       320       330       

>>XP_016882825 (OMIM: 600284) PREDICTED: RNA polymerase   (370 aa)
 initn: 255 init1: 148 opt: 247  Z-score: 213.9  bits: 48.7 E(85289): 3.6e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:134-365)

              290       300       310       320       330       340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
                                     ::     :. .:.:  ::   .. :   : 
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
           110       120       130       140       150        160  

              350       360        370       380       390         
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
       .  ..:.: :   ::: .   .  .:. : : .. .  ::.   : ::...:   :  : 
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
            170       180       190       200       210       220  

       400       410                        420       430       440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
         . ..: :   :                     :.. .:  :.:..::: :: .:..  
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
            230       240       250       260       270       280  

              450       460       470           480       490      
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
       .::..:......:......:: .: .  . :::: ..     .:: ..:  : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
            290       300       310       320       330         340

        500       510       520      
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT    
       :..:. :.:::.:::.....::...     
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
              350       360       370

>>XP_016882824 (OMIM: 600284) PREDICTED: RNA polymerase   (488 aa)
 initn: 255 init1: 148 opt: 247  Z-score: 212.4  bits: 48.8 E(85289): 4.3e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:252-483)

              290       300       310       320       330       340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
                                     ::     :. .:.:  ::   .. :   : 
XP_016 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
             230       240       250       260       270        280

              350       360        370       380       390         
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
       .  ..:.: :   ::: .   .  .:. : : .. .  ::.   : ::...:   :  : 
XP_016 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
              290       300       310       320       330       340

       400       410                        420       430       440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
         . ..: :   :                     :.. .:  :.:..::: :: .:..  
XP_016 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
              350       360       370       380       390       400

              450       460       470           480       490      
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
       .::..:......:......:: .: .  . :::: ..     .:: ..:  : ...:...
XP_016 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
              410       420       430       440         450        

        500       510       520      
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT    
       :..:. :.:::.:::.....::...     
XP_016 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
      460       470       480        

>>NP_006523 (OMIM: 600284) RNA polymerase II elongation   (621 aa)
 initn: 230 init1: 148 opt: 247  Z-score: 211.2  bits: 49.0 E(85289): 5e-05
Smith-Waterman score: 282; 28.1% identity (59.6% similar) in 235 aa overlap (311-521:385-616)

              290       300       310       320       330       340
pF1KE1 WDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPES
                                     ::     :. .:.:  ::   .. :   : 
NP_006 KLGVPNGREALLPTPGPPASTDTLSSSTHLPPRLEPPRAHDPLADVSNDLGHSGR-DCEH
          360       370       380       390       400        410   

              350       360        370       380       390         
pF1KE1 SYKSTPVPEVVQELPLTSPVDDFRQPRYS-SGGNFETPSKRAPAKGRAGRSKRTEQ--DH
       .  ..:.: :   ::: .   .  .:. : : .. .  ::.   : ::...:   :  : 
NP_006 GEAAAPAPTVRLGLPLLTDCAQPSRPHGSPSRSKPKKKSKKHKDKERAAEDKPRAQLPDC
           420       430       440       450       460       470   

       400       410                        420       430       440
pF1KE1 YETDYTTGGESCDE-----------------LEEDWIREYPPITSDQQRQLYKRNFDTGL
         . ..: :   :                     :.. .:  :.:..::: :: .:..  
NP_006 APATHATPGAPADTPGLNGTCSVSSVPTSTSETPDYLLKYAAISSSEQRQSYKNDFNAEY
           480       490       500       510       520       530   

              450       460       470           480       490      
pF1KE1 QEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAA----DEYNRLKQVKGSADYKSK
       .::..:......:......:: .: .  . :::: ..     .:: ..:  : ...:...
NP_006 SEYRDLHARIERITRRFTQLDAQLRQLSQGSEEYETTRGQILQEYRKIK--KTNTNYSQE
           540       550       560       570       580         590 

        500       510       520      
pF1KE1 KNHCKQLKSKLSHIKKMVGDYDRQKT    
       :..:. :.:::.:::.....::...     
NP_006 KHRCEYLHSKLAHIKRLIAEYDQRQLQAWP
             600       610       620 

>>XP_016864732 (OMIM: 601874) PREDICTED: RNA polymerase   (455 aa)
 initn: 238 init1: 100 opt: 232  Z-score: 200.7  bits: 46.6 E(85289): 0.00019
Smith-Waterman score: 232; 29.6% identity (65.1% similar) in 152 aa overlap (375-521:302-450)

          350       360       370       380       390       400    
pF1KE1 TPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTT
                                     :   ::    .. . :. . .   . : :.
XP_016 MSHKKSKKKSKKHKEKDQIKKHDIETIEEKEEDLKREEEIAKLNNSSPNSSGGVKEDCTA
             280       290       300       310       320       330 

           410       420       430       440       450       460   
pF1KE1 GGE-SCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKE
       . : :  ::  :.. .:  :.: .::: :: .:..  .::..:..... . ... .:: .
XP_016 SMEPSAIELP-DYLIKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQ
             340        350       360       370       380       390

           470       480           490       500       510         
pF1KE1 LDDYREESEEYMAAADE----YNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDR
              :.::. . .:    :...::  .: .:. .: .:. :..::.:::...:..:.
XP_016 RKRLSPGSKEYQNVHEEVLQEYQKIKQ--SSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQ
              400       410         420       430       440        

     520      
pF1KE1 QKT    
       :.     
XP_016 QQAESWS
      450     




522 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:22:49 2016 done: Sat Nov  5 19:22:50 2016
 Total Scan time: 10.410 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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