FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1415, 257 aa
  1>>>pF1KE1415 257 - 257 aa - 257 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9505+/-0.00073; mu= 17.1145+/- 0.044
 mean_var=69.4448+/-13.974, 0's: 0 Z-trim(109.7): 16  B-trim: 108 in 1/51
 Lambda= 0.153906
 statistics sampled from 11080 (11091) to 11080 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.341), width:  16
 Scan time:  1.520

The best scores are:                                      opt bits E(32554)
CCDS8211.1 FOLR1 gene_id:2348|Hs108|chr11          ( 257) 1920 434.8 2.8e-122
CCDS8212.1 FOLR2 gene_id:2350|Hs108|chr11          ( 255) 1382 315.4 2.5e-86
CCDS73344.1 FOLR3 gene_id:2352|Hs108|chr11         ( 245) 1368 312.2 2.1e-85
CCDS81615.1 IZUMO1R gene_id:390243|Hs108|chr11     ( 250) 1047 241.0 6.1e-64


>>CCDS8211.1 FOLR1 gene_id:2348|Hs108|chr11               (257 aa)
 initn: 1920 init1: 1920 opt: 1920  Z-score: 2308.9  bits: 434.8 E(32554): 2.8e-122
Smith-Waterman score: 1920; 100.0% identity (100.0% similar) in 257 aa overlap (1-257:1-257)

               10        20        30        40        50        60
pF1KE1 MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 RKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 DQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 DQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 YFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 YFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWA
              190       200       210       220       230       240

              250       
pF1KE1 AWPFLLSLALMLLWLLS
       :::::::::::::::::
CCDS82 AWPFLLSLALMLLWLLS
              250       

>>CCDS8212.1 FOLR2 gene_id:2350|Hs108|chr11               (255 aa)
 initn: 1350 init1: 1321 opt: 1382  Z-score: 1663.3  bits: 315.4 E(32554): 2.5e-86
Smith-Waterman score: 1382; 74.6% identity (87.3% similar) in 252 aa overlap (9-256:8-254)

               10        20        30        40        50        60
pF1KE1 MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPW
               :::::: ::..  :: :     :.::::::.::::: :::::::::.:: ::
CCDS82  MVWKWMPLLLLLVCVATMCSAQDR-----TDLLNVCMDAKHHKTKPGPEDKLHDQCSPW
                10        20             30        40        50    

               70        80        90       100       110       120
pF1KE1 RKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQV
       .:::::...:::: :::.: :: :::.:::.: :::::::::::::::::::::::::::
CCDS82 KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPACKRHFIQDTCLYECSPNLGPWIQQV
           60        70        80        90       100       110    

              130       140       150       160       170       180
pF1KE1 DQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHF
       .::::::: :.::::::::..:::::.::.:::::::.::.:::: ::: .:: :. :. 
CCDS82 NQSWRKERFLDVPLCKEDCQRWWEDCHTSHTCKSNWHRGWDWTSGVNKCPAGALCRTFES
          120       130       140       150       160       170    

              190       200       210       220       230          
pF1KE1 YFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMS-GAGPW
       :::::..::. .:.::::::::::::::::::::: :::::::::::::::::  .::  
CCDS82 YFPTPAALCEGLWSHSYKVSNYSRGSGRCIQMWFDSAQGNPNEEVARFYAAAMHVNAGEM
          180       190       200       210       220       230    

       240       250        
pF1KE1 --AAWPFLLSLALML-LWLLS
         ..  .:::::::: :::: 
CCDS82 LHGTGGLLLSLALMLQLWLLG
          240       250     

>>CCDS73344.1 FOLR3 gene_id:2352|Hs108|chr11              (245 aa)
 initn: 1409 init1: 1365 opt: 1368  Z-score: 1646.8  bits: 312.2 E(32554): 2.1e-85
Smith-Waterman score: 1368; 73.9% identity (90.3% similar) in 238 aa overlap (1-238:3-238)

                 10        20        30        40        50        
pF1KE1   MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCR
         :: .:    ::::. :...: :: : : :::.:::::::::::: .:.:::.:. :: 
CCDS73 MDMAWQMMQ--LLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCS
                 10        20        30        40        50        

       60        70        80        90       100       110        
pF1KE1 PWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQ
       ::.:::::...:::: :::.: :: :::.:::.: :.::::::::.:::::::::::::.
CCDS73 PWKKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIR
       60        70        80        90       100       110        

      120       130       140       150       160       170        
pF1KE1 QVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPF
       ::.:::::::.:::::::::::.::::::::::::::::::::::::.:.: .:: :. :
CCDS73 QVNQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTF
      120       130       140       150       160       170        

      180       190       200       210       220       230        
pF1KE1 HFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGP
       . :::::..::. .:.::.:::::::::::::::::: ::::::::::.::::::....:
CCDS73 ESYFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAP
      180       190       200       210       220       230        

      240       250       
pF1KE1 WAAWPFLLSLALMLLWLLS
                          
CCDS73 SRGIIDS            
      240                 

>>CCDS81615.1 IZUMO1R gene_id:390243|Hs108|chr11          (250 aa)
 initn: 1044 init1: 564 opt: 1047  Z-score: 1261.5  bits: 241.0 E(32554): 6.1e-64
Smith-Waterman score: 1047; 55.8% identity (74.7% similar) in 249 aa overlap (15-255:4-249)

               10        20         30        40        50         
pF1KE1 MAQRMTTQLLLLLVWVAVVGEAQTRI-AWARTELLNVCMNAKHHKEKPGPEDKLHEQCRP
                     :  .. :  : . .::  ::::.::::::::. :.:::::.:.: :
CCDS81            MACWWPLLLELWTVMPTWAGDELLNICMNAKHHKRVPSPEDKLYEECIP
                          10        20        30        40         

      60        70        80        90       100       110         
pF1KE1 WRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQ
       :. ::::. .:: ::: ::: :: :.  ::: . :.:..::::  :.:::::::::::: 
CCDS81 WKDNACCTLTTSWEAHLDVSPLYNFSLFHCGLLMPGCRKHFIQAICFYECSPNLGPWIQP
      50        60        70        80        90       100         

     120              130       140       150       160       170  
pF1KE1 VDQ-SW------RKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVG
       : . .:      . :::.:::::.::::.:::::: ::::::::. ::.:..: :.:  :
CCDS81 VGSLGWEVAPSGQGERVVNVPLCQEDCEEWWEDCRMSYTCKSNWRGGWDWSQGKNRCPKG
     110       120       130       140       150       160         

            180       190       200       210       220       230  
pF1KE1 AACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAA
       : : ::  :::::. ::.. :..:.:.:   :.::::.: ::.:::::::  :::..:  
CCDS81 AQCLPFSHYFPTPADLCEKTWSNSFKASPERRNSGRCLQKWFEPAQGNPNVAVARLFA--
     170       180       190       200       210       220         

            240       250       
pF1KE1 MSGAGPWAAWPFLLSLALMLLWLLS
        :.:  :     ..  .:.: .:  
CCDS81 -SSAPSWELSYTIMVCSLFLPFLS 
        230       240       250 




257 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 17:35:01 2016 done: Tue Nov  8 17:35:01 2016
 Total Scan time:  1.520 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]