FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1429, 536 aa 1>>>pF1KE1429 536 - 536 aa - 536 aa Library: /omim/omim.rfq.tfa 65951994 residues in 93482 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8592+/-0.00034; mu= 15.5351+/- 0.021 mean_var=77.6779+/-15.568, 0's: 0 Z-trim(114.4): 208 B-trim: 0 in 0/50 Lambda= 0.145521 statistics sampled from 25177 (25387) to 25177 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.272), width: 16 Scan time: 4.590 The best scores are: opt bits E(93482) NP_000915 (OMIM: 171891) calcium/calmodulin-depend ( 536) 3542 753.5 4.1e-217 XP_011536758 (OMIM: 171891) calcium/calmodulin-dep ( 537) 3287 699.9 5.4e-201 XP_016874921 (OMIM: 171891) calcium/calmodulin-dep ( 501) 3282 698.9 1e-200 NP_001159447 (OMIM: 171891) calcium/calmodulin-dep ( 516) 3282 698.9 1.1e-200 XP_016874922 (OMIM: 171891) calcium/calmodulin-dep ( 495) 3262 694.7 1.9e-199 NP_001275698 (OMIM: 171891) calcium/calmodulin-dep ( 495) 3262 694.7 1.9e-199 NP_001302463 (OMIM: 171891) calcium/calmodulin-dep ( 399) 2662 568.7 1.3e-161 NP_001275697 (OMIM: 171891) calcium/calmodulin-dep ( 399) 2662 568.7 1.3e-161 NP_001302464 (OMIM: 171891) calcium/calmodulin-dep ( 332) 2217 475.2 1.5e-133 NP_001308987 (OMIM: 602987,618140) calcium/calmodu ( 694) 2005 430.8 7e-120 XP_016867755 (OMIM: 602987,618140) calcium/calmodu ( 729) 2005 430.9 7.3e-120 XP_016867754 (OMIM: 602987,618140) calcium/calmodu ( 749) 2005 430.9 7.5e-120 NP_001177987 (OMIM: 602987,618140) calcium/calmodu ( 769) 2005 430.9 7.6e-120 NP_001308988 (OMIM: 602987,618140) calcium/calmodu ( 769) 2005 430.9 7.6e-120 XP_016867753 (OMIM: 602987,618140) calcium/calmodu ( 804) 2005 430.9 7.9e-120 XP_024308727 (OMIM: 171890) calcium/calmodulin-dep ( 535) 1980 425.5 2.1e-118 NP_001003683 (OMIM: 171890) calcium/calmodulin-dep ( 535) 1980 425.5 2.1e-118 XP_016859788 (OMIM: 171890) calcium/calmodulin-dep ( 535) 1980 425.5 2.1e-118 XP_016859790 (OMIM: 171890) calcium/calmodulin-dep ( 535) 1980 425.5 2.1e-118 XP_016859789 (OMIM: 171890) calcium/calmodulin-dep ( 535) 1980 425.5 2.1e-118 NP_005010 (OMIM: 171890) calcium/calmodulin-depend ( 545) 1980 425.5 2.2e-118 XP_016859785 (OMIM: 171890) calcium/calmodulin-dep ( 545) 1980 425.5 2.2e-118 XP_016859784 (OMIM: 171890) calcium/calmodulin-dep ( 545) 1980 425.5 2.2e-118 XP_016859787 (OMIM: 171890) calcium/calmodulin-dep ( 545) 1980 425.5 2.2e-118 XP_016859786 (OMIM: 171890) calcium/calmodulin-dep ( 545) 1980 425.5 2.2e-118 NP_001245241 (OMIM: 171890) calcium/calmodulin-dep ( 549) 1980 425.5 2.2e-118 XP_011509626 (OMIM: 171890) calcium/calmodulin-dep ( 553) 1980 425.5 2.2e-118 XP_011509625 (OMIM: 171890) calcium/calmodulin-dep ( 567) 1980 425.6 2.2e-118 XP_016859783 (OMIM: 171890) calcium/calmodulin-dep ( 586) 1980 425.6 2.3e-118 NP_001177985 (OMIM: 602987,618140) calcium/calmodu ( 634) 1978 425.2 3.3e-118 NP_005011 (OMIM: 602987,618140) calcium/calmodulin ( 634) 1978 425.2 3.3e-118 NP_001308985 (OMIM: 602987,618140) calcium/calmodu ( 634) 1978 425.2 3.3e-118 NP_001308986 (OMIM: 602987,618140) calcium/calmodu ( 634) 1978 425.2 3.3e-118 NP_001308984 (OMIM: 602987,618140) calcium/calmodu ( 709) 1978 425.2 3.6e-118 XP_016867756 (OMIM: 602987,618140) calcium/calmodu ( 709) 1978 425.2 3.6e-118 NP_001177986 (OMIM: 602987,618140) calcium/calmodu ( 709) 1978 425.2 3.6e-118 NP_001177988 (OMIM: 602987,618140) calcium/calmodu ( 709) 1978 425.2 3.6e-118 NP_001245242 (OMIM: 171890) calcium/calmodulin-dep ( 519) 1934 415.9 1.7e-115 NP_001350800 (OMIM: 171890) calcium/calmodulin-dep ( 529) 1934 415.9 1.7e-115 XP_011509627 (OMIM: 171890) calcium/calmodulin-dep ( 570) 1934 415.9 1.8e-115 NP_001245243 (OMIM: 171890) calcium/calmodulin-dep ( 501) 1760 379.3 1.6e-104 XP_011509628 (OMIM: 171890) calcium/calmodulin-dep ( 552) 1760 379.4 1.8e-104 XP_016869027 (OMIM: 171885) high affinity cAMP-spe ( 448) 601 136.0 2.6e-31 XP_011515842 (OMIM: 171885) high affinity cAMP-spe ( 456) 601 136.0 2.6e-31 NP_002594 (OMIM: 171885) high affinity cAMP-specif ( 456) 601 136.0 2.6e-31 NP_001229247 (OMIM: 171885) high affinity cAMP-spe ( 482) 601 136.0 2.8e-31 NP_061818 (OMIM: 604645) cAMP-specific 3',5'-cycli ( 450) 590 133.7 1.3e-30 XP_024307302 (OMIM: 600126) cAMP-specific 3',5'-cy ( 582) 528 120.7 1.3e-26 NP_006193 (OMIM: 600126) cAMP-specific 3',5'-cycli ( 647) 528 120.7 1.5e-26 XP_011526357 (OMIM: 600126) cAMP-specific 3',5'-cy ( 657) 528 120.7 1.5e-26 >>NP_000915 (OMIM: 171891) calcium/calmodulin-dependent (536 aa) initn: 3542 init1: 3542 opt: 3542 Z-score: 4019.6 bits: 753.5 E(93482): 4.1e-217 Smith-Waterman score: 3542; 100.0% identity (100.0% similar) in 536 aa overlap (1-536:1-536) 10 20 30 40 50 60 pF1KE1 MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 EYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 KFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHAL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 RTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 FRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 ALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 QIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVS 430 440 450 460 470 480 490 500 510 520 530 pF1KE1 FRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 490 500 510 520 530 >>XP_011536758 (OMIM: 171891) calcium/calmodulin-depende (537 aa) initn: 3287 init1: 3287 opt: 3287 Z-score: 3730.2 bits: 699.9 E(93482): 5.4e-201 Smith-Waterman score: 3287; 98.6% identity (98.8% similar) in 508 aa overlap (29-536:30-537) 10 20 30 40 50 pF1KE1 MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKN :. : : ::::::::::::::::::::: XP_011 MLPFSFFCLWMWSCCEDCSINYGSLDLWRKRSVIFLMPWLRYMVKQLENGEINIEELKKN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE1 LEYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE1 PKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHA 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE1 LRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE1 LRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE1 VFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE1 KALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQ 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE1 SQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVV 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE1 SFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 490 500 510 520 530 >>XP_016874921 (OMIM: 171891) calcium/calmodulin-depende (501 aa) initn: 3282 init1: 3282 opt: 3282 Z-score: 3725.0 bits: 698.9 E(93482): 1e-200 Smith-Waterman score: 3282; 100.0% identity (100.0% similar) in 498 aa overlap (39-536:4-501) 10 20 30 40 50 60 pF1KE1 PEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLE :::::::::::::::::::::::::::::: XP_016 MIRLRYMVKQLENGEINIEELKKNLEYTASLLE 10 20 30 70 80 90 100 110 120 pF1KE1 AVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE1 VQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE1 TRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCL 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE1 SEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE1 MNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHA 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE1 ADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFI 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE1 VEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKR 400 410 420 430 440 450 490 500 510 520 530 pF1KE1 IQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 460 470 480 490 500 >>NP_001159447 (OMIM: 171891) calcium/calmodulin-depende (516 aa) initn: 3282 init1: 3282 opt: 3282 Z-score: 3724.8 bits: 698.9 E(93482): 1.1e-200 Smith-Waterman score: 3282; 100.0% identity (100.0% similar) in 498 aa overlap (39-536:19-516) 10 20 30 40 50 60 pF1KE1 PEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLE :::::::::::::::::::::::::::::: NP_001 MANPVPVQRSHLQGPILRLRYMVKQLENGEINIEELKKNLEYTASLLE 10 20 30 40 70 80 90 100 110 120 pF1KE1 AVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 VQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 TRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 SEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 MNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHA 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE1 ADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFI 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE1 VEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKR 410 420 430 440 450 460 490 500 510 520 530 pF1KE1 IQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 470 480 490 500 510 >>XP_016874922 (OMIM: 171891) calcium/calmodulin-depende (495 aa) initn: 3262 init1: 3262 opt: 3262 Z-score: 3702.4 bits: 694.7 E(93482): 1.9e-199 Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 495 aa overlap (42-536:1-495) 20 30 40 50 60 70 pF1KE1 LEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLEAVY :::::::::::::::::::::::::::::: XP_016 MVKQLENGEINIEELKKNLEYTASLLEAVY 10 20 30 80 90 100 110 120 130 pF1KE1 IDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 GIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE1 NLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEI 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE1 ELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNI 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE1 FINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADI 280 290 300 310 320 330 380 390 400 410 420 430 pF1KE1 SHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 340 350 360 370 380 390 440 450 460 470 480 490 pF1KE1 TFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQE 400 410 420 430 440 450 500 510 520 530 pF1KE1 NKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD ::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 460 470 480 490 >>NP_001275698 (OMIM: 171891) calcium/calmodulin-depende (495 aa) initn: 3262 init1: 3262 opt: 3262 Z-score: 3702.4 bits: 694.7 E(93482): 1.9e-199 Smith-Waterman score: 3262; 100.0% identity (100.0% similar) in 495 aa overlap (42-536:1-495) 20 30 40 50 60 70 pF1KE1 LEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLEAVY :::::::::::::::::::::::::::::: NP_001 MVKQLENGEINIEELKKNLEYTASLLEAVY 10 20 30 80 90 100 110 120 130 pF1KE1 IDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE1 GIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE1 NLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEI 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE1 ELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNI 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE1 FINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADI 280 290 300 310 320 330 380 390 400 410 420 430 pF1KE1 SHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEP 340 350 360 370 380 390 440 450 460 470 480 490 pF1KE1 TFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQE 400 410 420 430 440 450 500 510 520 530 pF1KE1 NKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD ::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD 460 470 480 490 >>NP_001302463 (OMIM: 171891) calcium/calmodulin-depende (399 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 3023.1 bits: 568.7 E(93482): 1.3e-161 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 399 aa overlap (138-536:1-399) 110 120 130 140 150 160 pF1KE1 QARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFD :::::::::::::::::::::::::::::: NP_001 MFRRTYTSVGPTYSTAVLNCLKNLDLWCFD 10 20 30 170 180 190 200 210 220 pF1KE1 VFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIH 40 50 60 70 80 90 230 240 250 260 270 280 pF1KE1 AADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYN 100 110 120 130 140 150 290 300 310 320 330 340 pF1KE1 DRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMK 160 170 180 190 200 210 350 360 370 380 390 400 pF1KE1 TALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFS 220 230 240 250 260 270 410 420 430 440 450 460 pF1KE1 PLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSL 280 290 300 310 320 330 470 480 490 500 510 520 pF1KE1 DVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAED 340 350 360 370 380 390 530 pF1KE1 EHNQNGNLD ::::::::: NP_001 EHNQNGNLD >>NP_001275697 (OMIM: 171891) calcium/calmodulin-depende (399 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 3023.1 bits: 568.7 E(93482): 1.3e-161 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 399 aa overlap (138-536:1-399) 110 120 130 140 150 160 pF1KE1 QARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFD :::::::::::::::::::::::::::::: NP_001 MFRRTYTSVGPTYSTAVLNCLKNLDLWCFD 10 20 30 170 180 190 200 210 220 pF1KE1 VFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIH 40 50 60 70 80 90 230 240 250 260 270 280 pF1KE1 AADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYN 100 110 120 130 140 150 290 300 310 320 330 340 pF1KE1 DRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMK 160 170 180 190 200 210 350 360 370 380 390 400 pF1KE1 TALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFS 220 230 240 250 260 270 410 420 430 440 450 460 pF1KE1 PLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSL 280 290 300 310 320 330 470 480 490 500 510 520 pF1KE1 DVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAED 340 350 360 370 380 390 530 pF1KE1 EHNQNGNLD ::::::::: NP_001 EHNQNGNLD >>NP_001302464 (OMIM: 171891) calcium/calmodulin-depende (332 aa) initn: 2217 init1: 2217 opt: 2217 Z-score: 2519.4 bits: 475.2 E(93482): 1.5e-133 Smith-Waterman score: 2217; 100.0% identity (100.0% similar) in 332 aa overlap (205-536:1-332) 180 190 200 210 220 230 pF1KE1 ADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQT :::::::::::::::::::::::::::::: NP_001 MSFLDALETGYGKYKNPYHNQIHAADVTQT 10 20 30 240 250 260 270 280 290 pF1KE1 VHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLEN 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE1 HHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLE 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE1 RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTS 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE1 TLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDP 220 230 240 250 260 270 480 490 500 510 520 530 pF1KE1 NPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGN 280 290 300 310 320 330 pF1KE1 LD :: NP_001 LD >>NP_001308987 (OMIM: 602987,618140) calcium/calmodulin- (694 aa) initn: 2051 init1: 1243 opt: 2005 Z-score: 2274.0 bits: 430.8 E(93482): 7e-120 Smith-Waterman score: 2023; 61.0% identity (81.9% similar) in 518 aa overlap (5-499:77-584) 10 20 30 pF1KE1 MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIK :: : :.: . :: . : .. .: NP_001 SKSQNCLWNSLIDGLTGNVKEKPRPTIVHDPRPPEEILAD-------ELPQLDSPEVLVK 50 60 70 80 90 40 50 60 70 80 90 pF1KE1 LRSLLRYMVKQLENGEINIEELKKNLEYTASLLEAVYIDETRQILDTEDELQELRSDAVP :: .::::: :: .. .:::::::.:..::.:::::::..:::::::....::::: NP_001 TSFRLRSLVKQLERGEASVVDLKKNLEYAATVLESVYIDETRRLLDTEDELSDIQSDAVP 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE1 SEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAV ::::::::::::.: ::..:::.:.:::::::::::::::.::: . :: .: :: NP_001 SEVRDWLASTFTRQMGMMLRRSDEKPRFKSIVHAVQAGIFVERMYRRTSNMVGLSYPPAV 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE1 LNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETG .. ::..: : :::::::.:. ::::. : .:::::..:::::::: :.::..:::.: NP_001 IEALKDVDKWSFDVFSLNEASGDHALKFIFYELLTRYDLISRFKIPISALVSFVEALEVG 220 230 240 250 260 270 220 230 240 250 260 270 pF1KE1 YGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSF :.:.:::::: .:::::::::: .: .::... :.:.:..::::.:::::::::::::.: NP_001 YSKHKNPYHNLMHAADVTQTVHYLLYKTGVANWLTELEIFAIIFSAAIHDYEHTGTTNNF 280 290 300 310 320 330 280 290 300 310 320 330 pF1KE1 HIQTKSECAIVYNDRSVLENHHISSVFRLMQDDE-MNIFINLTKDEFVELRALVIEMVLA ::::.:. ::.:::::::::::.:...::.:::: :::.:::.::.. :.:.::::::.: NP_001 HIQTRSDPAILYNDRSVLENHHLSAAYRLLQDDEEMNILINLSKDDWREFRTLVIEMVMA 340 350 360 370 380 390 340 350 360 370 380 390 pF1KE1 TDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFF :::::::::.:.::::::: : :.:::::::.::.::::::.: : .: ::: .:.:::: NP_001 TDMSCHFQQIKAMKTALQQPEAIEKPKALSLMLHTADISHPAKAWDLHHRWTMSLLEEFF 400 410 420 430 440 450 400 410 420 430 440 450 pF1KE1 RQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSK ::::.:::::::::::::: ::.:::::.:::::::::::.::::..:: :.:: :: :. NP_001 RQGDREAELGLPFSPLCDRKSTMVAQSQVGFIDFIVEPTFTVLTDMTEKIVSPLIDETSQ 460 470 480 490 500 510 460 470 480 490 pF1KE1 SKNQPSFQWRQPSLD-VEVGD---------------P-NPDVVS-----FRSTWVKRIQE . . . :. ::. . .: : : .:.: :..::.. .. NP_001 TGGTGQ---RRSSLNSISSSDAKRSGVKTSGSEGSAPINNSVISVDYKSFKATWTEVVHI 520 530 540 550 560 570 500 510 520 530 pF1KE1 NKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD :...:. . NP_001 NRERWRAKVPKEEKAKKEAEEKARLAAEEQQKEMEAKSQAEEGASGKAEKKTSGETKNQV 580 590 600 610 620 630 536 residues in 1 query sequences 65951994 residues in 93482 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Jun 19 14:27:42 2019 done: Wed Jun 19 14:27:42 2019 Total Scan time: 4.590 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]