FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1444, 274 aa 1>>>pF1KE1444 274 - 274 aa - 274 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4207+/-0.000896; mu= 13.9879+/- 0.054 mean_var=62.5323+/-12.599, 0's: 0 Z-trim(104.7): 20 B-trim: 0 in 0/51 Lambda= 0.162189 statistics sampled from 8012 (8024) to 8012 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.246), width: 16 Scan time: 2.290 The best scores are: opt bits E(32554) CCDS10883.1 NQO1 gene_id:1728|Hs108|chr16 ( 274) 1833 437.6 4.7e-123 CCDS32471.1 NQO1 gene_id:1728|Hs108|chr16 ( 236) 933 226.9 1e-59 CCDS32472.1 NQO1 gene_id:1728|Hs108|chr16 ( 240) 926 225.3 3.2e-59 CCDS4481.1 NQO2 gene_id:4835|Hs108|chr6 ( 231) 736 180.8 7.5e-46 CCDS67067.1 NQO1 gene_id:1728|Hs108|chr16 ( 202) 696 171.5 4.4e-43 CCDS75388.1 NQO2 gene_id:4835|Hs108|chr6 ( 193) 309 80.9 7.6e-16 >>CCDS10883.1 NQO1 gene_id:1728|Hs108|chr16 (274 aa) initn: 1833 init1: 1833 opt: 1833 Z-score: 2322.7 bits: 437.6 E(32554): 4.7e-123 Smith-Waterman score: 1833; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 190 200 210 220 230 240 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK :::::::::::::::::::::::::::::::::: CCDS10 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 250 260 270 >>CCDS32471.1 NQO1 gene_id:1728|Hs108|chr16 (236 aa) initn: 921 init1: 921 opt: 933 Z-score: 1185.6 bits: 226.9 E(32554): 1e-59 Smith-Waterman score: 1468; 86.1% identity (86.1% similar) in 274 aa overlap (1-274:1-236) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV ::::::::::::::::::::::::::::::::::::::::: CCDS32 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC ::::::::::::::::::::::::::::::::::::::::: CCDS32 -------------------SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 110 120 130 140 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 150 160 170 180 190 200 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK :::::::::::::::::::::::::::::::::: CCDS32 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 210 220 230 >>CCDS32472.1 NQO1 gene_id:1728|Hs108|chr16 (240 aa) initn: 926 init1: 926 opt: 926 Z-score: 1176.7 bits: 225.3 E(32554): 3.2e-59 Smith-Waterman score: 1532; 87.6% identity (87.6% similar) in 274 aa overlap (1-274:1-240) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC :::::::::::::::::::: :::::: CCDS32 FIGEFAYTYAAMYDKGPFRS----------------------------------GILHFC 130 140 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 150 160 170 180 190 200 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK :::::::::::::::::::::::::::::::::: CCDS32 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 210 220 230 240 >>CCDS4481.1 NQO2 gene_id:4835|Hs108|chr6 (231 aa) initn: 740 init1: 715 opt: 736 Z-score: 936.7 bits: 180.8 E(32554): 7.5e-46 Smith-Waterman score: 736; 48.4% identity (76.5% similar) in 221 aa overlap (1-221:1-221) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :.:...::: ::.: ::: ..:..:. :...: :. :::::::..: . ::::: : CCDS44 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV ..: :.: .:. :::. :. ::. ::::.. :::::::::: ::.::::::::..:: CCDS44 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC . ::. ..::.: ...: :.::.::::.. ::. :..:: .:::.: : :::: CCDS44 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK ::.:: ::.... . . : .. .:..::..:: : :. CCDS44 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 190 200 210 220 230 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK >>CCDS67067.1 NQO1 gene_id:1728|Hs108|chr16 (202 aa) initn: 696 init1: 696 opt: 696 Z-score: 887.0 bits: 171.5 E(32554): 4.4e-43 Smith-Waterman score: 1177; 73.7% identity (73.7% similar) in 274 aa overlap (1-274:1-202) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV ::::::::::::::::::::::::::::::::::::::::: CCDS67 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC ::::::: CCDS67 -----------------------------------------------------SGILHFC 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 110 120 130 140 150 160 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK :::::::::::::::::::::::::::::::::: CCDS67 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 170 180 190 200 >>CCDS75388.1 NQO2 gene_id:4835|Hs108|chr6 (193 aa) initn: 565 init1: 306 opt: 309 Z-score: 397.9 bits: 80.9 E(32554): 7.6e-16 Smith-Waterman score: 502; 39.4% identity (62.9% similar) in 221 aa overlap (1-221:1-183) 10 20 30 40 50 60 pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL :.:...::: ::.: ::: ..:..:. :...: :. :::::::..: . ::::: : CCDS75 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV ..: :.: .:. :::. :. ::. ::::.. ::::::: CCDS75 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQ------------------- 70 80 90 100 130 140 150 160 170 180 pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC .: :.::.::::.. ::. :..:: .:::.: : :::: CCDS75 -------------------GKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 110 120 130 140 190 200 210 220 230 240 pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK ::.:: ::.... . . : .. .:..::..:: : :. CCDS75 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ 150 160 170 180 190 250 260 270 pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 02:12:25 2016 done: Mon Nov 7 02:12:25 2016 Total Scan time: 2.290 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]