Result of FASTA (omim) for pF1KE1444
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1444, 274 aa
  1>>>pF1KE1444 274 - 274 aa - 274 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9789+/-0.000376; mu= 16.5613+/- 0.023
 mean_var=60.3645+/-12.449, 0's: 0 Z-trim(111.7): 28  B-trim: 80 in 1/54
 Lambda= 0.165076
 statistics sampled from 20336 (20356) to 20336 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.239), width:  16
 Scan time:  6.710

The best scores are:                                      opt bits E(85289)
NP_000894 (OMIM: 125860) NAD(P)H dehydrogenase [qu ( 274) 1833 445.0 6.9e-125
NP_001020605 (OMIM: 125860) NAD(P)H dehydrogenase  ( 236)  933 230.7   2e-60
NP_001020604 (OMIM: 125860) NAD(P)H dehydrogenase  ( 240)  926 229.0 6.5e-60
NP_000895 (OMIM: 114480,160998) ribosyldihydronico ( 231)  736 183.7 2.6e-46
NP_001277150 (OMIM: 114480,160998) ribosyldihydron ( 231)  736 183.7 2.6e-46
NP_001305869 (OMIM: 114480,160998) ribosyldihydron ( 231)  736 183.7 2.6e-46
NP_001273066 (OMIM: 125860) NAD(P)H dehydrogenase  ( 202)  696 174.2 1.7e-43
NP_001277151 (OMIM: 114480,160998) ribosyldihydron ( 193)  309 82.0 9.4e-16


>>NP_000894 (OMIM: 125860) NAD(P)H dehydrogenase [quinon  (274 aa)
 initn: 1833 init1: 1833 opt: 1833  Z-score: 2363.1  bits: 445.0 E(85289): 6.9e-125
Smith-Waterman score: 1833; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
              190       200       210       220       230       240

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
       ::::::::::::::::::::::::::::::::::
NP_000 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
              250       260       270    

>>NP_001020605 (OMIM: 125860) NAD(P)H dehydrogenase [qui  (236 aa)
 initn: 921 init1: 921 opt: 933  Z-score: 1205.7  bits: 230.7 E(85289): 2e-60
Smith-Waterman score: 1468; 86.1% identity (86.1% similar) in 274 aa overlap (1-274:1-236)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       :::::::::::::::::::::::::::::::::::::::::                   
NP_001 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ-------------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
                          :::::::::::::::::::::::::::::::::::::::::
NP_001 -------------------SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
                                110       120       130       140  

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
            150       160       170       180       190       200  

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
       ::::::::::::::::::::::::::::::::::
NP_001 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
            210       220       230      

>>NP_001020604 (OMIM: 125860) NAD(P)H dehydrogenase [qui  (240 aa)
 initn: 926 init1: 926 opt: 926  Z-score: 1196.6  bits: 229.0 E(85289): 6.5e-60
Smith-Waterman score: 1532; 87.6% identity (87.6% similar) in 274 aa overlap (1-274:1-240)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
       ::::::::::::::::::::                                  ::::::
NP_001 FIGEFAYTYAAMYDKGPFRS----------------------------------GILHFC
              130       140                                        

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
        150       160       170       180       190       200      

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
       ::::::::::::::::::::::::::::::::::
NP_001 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
        210       220       230       240

>>NP_000895 (OMIM: 114480,160998) ribosyldihydronicotina  (231 aa)
 initn: 740 init1: 715 opt: 736  Z-score: 952.3  bits: 183.7 E(85289): 2.6e-46
Smith-Waterman score: 736; 48.4% identity (76.5% similar) in 221 aa overlap (1-221:1-221)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       :.:...::: ::.:  ::: ..:..:.  :...:  :. :::::::..:  . ::::: :
NP_000 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ..:  :.: .:.  :::.  :. ::. ::::.. :::::::::: ::.::::::::..::
NP_000 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
       .   ::.   ..::.: ...: :.::.::::.. ::.  :..::   .:::.: : ::::
NP_000 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::.:: ::....   .  . :  .. .:..::..:: : :.                   
NP_000 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ         
              190       200       210       220       230          

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK

>>NP_001277150 (OMIM: 114480,160998) ribosyldihydronicot  (231 aa)
 initn: 740 init1: 715 opt: 736  Z-score: 952.3  bits: 183.7 E(85289): 2.6e-46
Smith-Waterman score: 736; 48.4% identity (76.5% similar) in 221 aa overlap (1-221:1-221)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       :.:...::: ::.:  ::: ..:..:.  :...:  :. :::::::..:  . ::::: :
NP_001 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ..:  :.: .:.  :::.  :. ::. ::::.. :::::::::: ::.::::::::..::
NP_001 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
       .   ::.   ..::.: ...: :.::.::::.. ::.  :..::   .:::.: : ::::
NP_001 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::.:: ::....   .  . :  .. .:..::..:: : :.                   
NP_001 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ         
              190       200       210       220       230          

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK

>>NP_001305869 (OMIM: 114480,160998) ribosyldihydronicot  (231 aa)
 initn: 740 init1: 715 opt: 736  Z-score: 952.3  bits: 183.7 E(85289): 2.6e-46
Smith-Waterman score: 736; 48.4% identity (76.5% similar) in 221 aa overlap (1-221:1-221)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       :.:...::: ::.:  ::: ..:..:.  :...:  :. :::::::..:  . ::::: :
NP_001 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ..:  :.: .:.  :::.  :. ::. ::::.. :::::::::: ::.::::::::..::
NP_001 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
       .   ::.   ..::.: ...: :.::.::::.. ::.  :..::   .:::.: : ::::
NP_001 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::.:: ::....   .  . :  .. .:..::..:: : :.                   
NP_001 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ         
              190       200       210       220       230          

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK

>>NP_001273066 (OMIM: 125860) NAD(P)H dehydrogenase [qui  (202 aa)
 initn: 696 init1: 696 opt: 696  Z-score: 901.7  bits: 174.2 E(85289): 1.7e-43
Smith-Waterman score: 1177; 73.7% identity (73.7% similar) in 274 aa overlap (1-274:1-202)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       :::::::::::::::::::::::::::::::::::::::::                   
NP_001 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ-------------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
                                                            :::::::
NP_001 -----------------------------------------------------SGILHFC
                                                                   

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
      110       120       130       140       150       160        

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
       ::::::::::::::::::::::::::::::::::
NP_001 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
      170       180       190       200  

>>NP_001277151 (OMIM: 114480,160998) ribosyldihydronicot  (193 aa)
 initn: 565 init1: 306 opt: 309  Z-score: 403.8  bits: 82.0 E(85289): 9.4e-16
Smith-Waterman score: 502; 39.4% identity (62.9% similar) in 221 aa overlap (1-221:1-183)

               10        20        30        40        50        60
pF1KE1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
       :.:...::: ::.:  ::: ..:..:.  :...:  :. :::::::..:  . ::::: :
NP_001 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
       ..:  :.: .:.  :::.  :. ::. ::::.. :::::::                   
NP_001 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQ-------------------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KE1 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
                          .: :.::.::::.. ::.  :..::   .:::.: : ::::
NP_001 -------------------GKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
                                110       120       130       140  

              190       200       210       220       230       240
pF1KE1 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
       ::.:: ::....   .  . :  .. .:..::..:: : :.                   
NP_001 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ         
            150       160       170       180       190            

              250       260       270    
pF1KE1 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK




274 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 02:12:26 2016 done: Mon Nov  7 02:12:27 2016
 Total Scan time:  6.710 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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