Result of FASTA (omim) for
pF1KE1499
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1499, 3097 aa
1>>>pF1KE1499 3097 - 3097 aa - 3097 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.0162+/-0.000688; mu= -25.1520+/- 0.043
mean_var=964.6688+/-201.709, 0's: 0 Z-trim(120.5): 1024 B-trim: 0 in 0/57
Lambda= 0.041294
statistics sampled from 34620 (35781) to 34620 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.42), width: 16
Scan time: 24.930
The best scores are: opt bits E(85289)
NP_009049 (OMIM: 601893,617061) triple functional (3097) 20546 1242.6 0
XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093) 20507 1240.3 0
XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 20215 1222.9 0
XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058) 20215 1222.9 0
XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076) 20207 1222.4 0
XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 20165 1219.9 0
XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880) 19041 1153.0 0
XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 17213 1044.0 0
XP_006713876 (OMIM: 604605,608901) PREDICTED: kali (2966) 9432 580.5 1.4e-163
XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643) 8769 540.8 7.1e-152
NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641) 8721 537.9 5.1e-151
XP_006713875 (OMIM: 604605,608901) PREDICTED: kali (2975) 7565 469.3 4.2e-130
XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652) 7122 442.6 2.5e-122
NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650) 7074 439.8 1.8e-121
XP_016862920 (OMIM: 604605,608901) PREDICTED: kali (2398) 3874 249.3 5.6e-64
XP_011511582 (OMIM: 604605,608901) PREDICTED: kali (2987) 3874 249.4 6.6e-64
XP_011511585 (OMIM: 604605,608901) PREDICTED: kali (2401) 3868 249.0 7.2e-64
XP_016862918 (OMIM: 604605,608901) PREDICTED: kali (2968) 3868 249.0 8.4e-64
XP_011511581 (OMIM: 604605,608901) PREDICTED: kali (2987) 3868 249.0 8.4e-64
XP_006713873 (OMIM: 604605,608901) PREDICTED: kali (2988) 3868 249.0 8.4e-64
XP_006713878 (OMIM: 604605,608901) PREDICTED: kali (1665) 3837 246.9 2e-63
XP_016862922 (OMIM: 604605,608901) PREDICTED: kali (1656) 3834 246.8 2.3e-63
XP_016862921 (OMIM: 604605,608901) PREDICTED: kali (2366) 3837 247.1 2.6e-63
XP_011511587 (OMIM: 604605,608901) PREDICTED: kali (2367) 3837 247.1 2.6e-63
XP_016862919 (OMIM: 604605,608901) PREDICTED: kali (2955) 3837 247.2 3e-63
XP_006713877 (OMIM: 604605,608901) PREDICTED: kali (2956) 3837 247.2 3e-63
XP_006713874 (OMIM: 604605,608901) PREDICTED: kali (2979) 3834 247.0 3.4e-63
NP_001309917 (OMIM: 604605,608901) kalirin isoform (2396) 3826 246.5 4.1e-63
NP_001019831 (OMIM: 604605,608901) kalirin isoform (2986) 3820 246.2 6.1e-63
NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613) 3789 244.1 1.4e-62
NP_003938 (OMIM: 604605,608901) kalirin isoform 2 (1663) 3789 244.1 1.5e-62
NP_001309918 (OMIM: 604605,608901) kalirin isoform (1654) 3786 243.9 1.6e-62
XP_011511583 (OMIM: 604605,608901) PREDICTED: kali (2977) 3786 244.2 2.5e-62
NP_001309924 (OMIM: 604605,608901) kalirin isoform ( 701) 1603 113.5 1.3e-23
NP_001309926 (OMIM: 604605,608901) kalirin isoform ( 699) 1599 113.3 1.5e-23
NP_001309925 (OMIM: 604605,608901) kalirin isoform ( 700) 1599 113.3 1.5e-23
NP_891992 (OMIM: 610215) rho guanine nucleotide ex ( 580) 1594 112.9 1.6e-23
NP_001104740 (OMIM: 610215) rho guanine nucleotide ( 619) 1594 112.9 1.7e-23
NP_001309928 (OMIM: 604605,608901) kalirin isoform ( 668) 1500 107.3 8.6e-22
NP_001309927 (OMIM: 604605,608901) kalirin isoform ( 669) 1498 107.2 9.4e-22
NP_001309930 (OMIM: 604605,608901) kalirin isoform ( 667) 1496 107.1 1e-21
NP_001309929 (OMIM: 604605,608901) kalirin isoform ( 668) 1494 107.0 1.1e-21
NP_001309922 (OMIM: 604605,608901) kalirin isoform (1288) 1294 95.3 6.8e-18
NP_008995 (OMIM: 604605,608901) kalirin isoform 3 (1289) 1294 95.3 6.8e-18
NP_001309923 (OMIM: 604605,608901) kalirin isoform ( 709) 1124 85.0 5e-15
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 748 62.4 2e-08
NP_001339 (OMIM: 603289) death-associated protein ( 454) 748 62.4 2e-08
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 757 63.2 2.1e-08
NP_001275659 (OMIM: 600831) death-associated prote (1430) 757 63.4 3.1e-08
NP_001275658 (OMIM: 600831) death-associated prote (1430) 757 63.4 3.1e-08
>>NP_009049 (OMIM: 601893,617061) triple functional doma (3097 aa)
initn: 20546 init1: 20546 opt: 20546 Z-score: 6636.0 bits: 1242.6 E(85289): 0
Smith-Waterman score: 20546; 100.0% identity (100.0% similar) in 3097 aa overlap (1-3097:1-3097)
10 20 30 40 50 60
pF1KE1 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE1 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE1 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE1 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE1 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE1 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE1 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE1 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE1 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE1 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE1 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE1 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE1 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE1 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE1 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE1 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE1 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE1 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE1 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE1 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE1 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE1 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE1 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE1 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE1 KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE1 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KE1 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KE1 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KE1 VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
2890 2900 2910 2920 2930 2940
2950 2960 2970 2980 2990 3000
pF1KE1 VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
2950 2960 2970 2980 2990 3000
3010 3020 3030 3040 3050 3060
pF1KE1 CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
3010 3020 3030 3040 3050 3060
3070 3080 3090
pF1KE1 LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
:::::::::::::::::::::::::::::::::::::
NP_009 LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
3070 3080 3090
>>XP_016865290 (OMIM: 601893,617061) PREDICTED: triple f (3093 aa)
initn: 17714 init1: 17714 opt: 20507 Z-score: 6623.4 bits: 1240.3 E(85289): 0
Smith-Waterman score: 20507; 99.9% identity (99.9% similar) in 3097 aa overlap (1-3097:1-3093)
10 20 30 40 50 60
pF1KE1 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE1 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE1 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE1 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE1 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE1 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE1 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE1 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE1 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE1 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE1 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE1 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE1 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE1 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE1 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE1 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE1 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE1 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE1 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE1 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE1 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE1 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE1 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE1 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE1 KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
:::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_016 KSEKKDKDGKREGKLENGYRKSREGLSN----KLLNPNYIYDVPPEFVIPLSEVTCETGE
2650 2660 2670 2680 2690
2710 2720 2730 2740 2750 2760
pF1KE1 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
2700 2710 2720 2730 2740 2750
2770 2780 2790 2800 2810 2820
pF1KE1 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
2760 2770 2780 2790 2800 2810
2830 2840 2850 2860 2870 2880
pF1KE1 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
2820 2830 2840 2850 2860 2870
2890 2900 2910 2920 2930 2940
pF1KE1 VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
2880 2890 2900 2910 2920 2930
2950 2960 2970 2980 2990 3000
pF1KE1 VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEET
2940 2950 2960 2970 2980 2990
3010 3020 3030 3040 3050 3060
pF1KE1 CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGV
3000 3010 3020 3030 3040 3050
3070 3080 3090
pF1KE1 LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
:::::::::::::::::::::::::::::::::::::
XP_016 LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
3060 3070 3080 3090
>>XP_011512411 (OMIM: 601893,617061) PREDICTED: triple f (3048 aa)
initn: 20215 init1: 20215 opt: 20215 Z-score: 6529.5 bits: 1222.9 E(85289): 0
Smith-Waterman score: 20215; 100.0% identity (100.0% similar) in 3045 aa overlap (53-3097:4-3048)
30 40 50 60 70 80
pF1KE1 AAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDK
::::::::::::::::::::::::::::::
XP_011 MAEGFRKNDEMKAMDVLPILKEKVAYLSGGRDK
10 20 30
90 100 110 120 130 140
pF1KE1 RGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 KILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEF
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 DGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 LKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 QHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQT
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE1 QHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERST
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE1 LLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVS
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE1 QDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRL
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE1 HQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYT
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE1 NADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKE
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE1 LWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSA
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE1 ISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDL
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE1 ESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQAS
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE1 GVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGW
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE1 IRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDM
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE1 DMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCG
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE1 GADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHI
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE1 KAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYL
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE1 STHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVT
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE1 AVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHEL
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE1 NEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFG
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE1 NMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAG
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE1 SYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPK
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500 1510 1520
pF1KE1 RANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEV
1420 1430 1440 1450 1460 1470
1530 1540 1550 1560 1570 1580
pF1KE1 KDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDW
1480 1490 1500 1510 1520 1530
1590 1600 1610 1620 1630 1640
pF1KE1 IKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIAS
1540 1550 1560 1570 1580 1590
1650 1660 1670 1680 1690 1700
pF1KE1 RTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTD
1600 1610 1620 1630 1640 1650
1710 1720 1730 1740 1750 1760
pF1KE1 RSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQS
1660 1670 1680 1690 1700 1710
1770 1780 1790 1800 1810 1820
pF1KE1 SPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSA
1720 1730 1740 1750 1760 1770
1830 1840 1850 1860 1870 1880
pF1KE1 ATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQ
1780 1790 1800 1810 1820 1830
1890 1900 1910 1920 1930 1940
pF1KE1 PDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSF
1840 1850 1860 1870 1880 1890
1950 1960 1970 1980 1990 2000
pF1KE1 NPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKED
1900 1910 1920 1930 1940 1950
2010 2020 2030 2040 2050 2060
pF1KE1 GVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYC
1960 1970 1980 1990 2000 2010
2070 2080 2090 2100 2110 2120
pF1KE1 QNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKAS
2020 2030 2040 2050 2060 2070
2130 2140 2150 2160 2170 2180
pF1KE1 LDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPR
2080 2090 2100 2110 2120 2130
2190 2200 2210 2220 2230 2240
pF1KE1 CRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRT
2140 2150 2160 2170 2180 2190
2250 2260 2270 2280 2290 2300
pF1KE1 GDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGS
2200 2210 2220 2230 2240 2250
2310 2320 2330 2340 2350 2360
pF1KE1 GGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAE
2260 2270 2280 2290 2300 2310
2370 2380 2390 2400 2410 2420
pF1KE1 ADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGA
2320 2330 2340 2350 2360 2370
2430 2440 2450 2460 2470 2480
pF1KE1 ANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKG
2380 2390 2400 2410 2420 2430
2490 2500 2510 2520 2530 2540
pF1KE1 GSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQS
2440 2450 2460 2470 2480 2490
2550 2560 2570 2580 2590 2600
pF1KE1 NGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAA
2500 2510 2520 2530 2540 2550
2610 2620 2630 2640 2650 2660
pF1KE1 EGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKS
2560 2570 2580 2590 2600 2610
2670 2680 2690 2700 2710 2720
pF1KE1 REGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPE
2620 2630 2640 2650 2660 2670
2730 2740 2750 2760 2770 2780
pF1KE1 HNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMD
2680 2690 2700 2710 2720 2730
2790 2800 2810 2820 2830 2840
pF1KE1 GIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELG
2740 2750 2760 2770 2780 2790
2850 2860 2870 2880 2890 2900
pF1KE1 ILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEA
2800 2810 2820 2830 2840 2850
2910 2920 2930 2940 2950 2960
pF1KE1 VRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPE
2860 2870 2880 2890 2900 2910
2970 2980 2990 3000 3010 3020
pF1KE1 IILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQK
2920 2930 2940 2950 2960 2970
3030 3040 3050 3060 3070 3080
pF1KE1 AKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPI
2980 2990 3000 3010 3020 3030
3090
pF1KE1 RSIKNFLQSRLLPRV
:::::::::::::::
XP_011 RSIKNFLQSRLLPRV
3040
>>XP_011512410 (OMIM: 601893,617061) PREDICTED: triple f (3058 aa)
initn: 20215 init1: 20215 opt: 20215 Z-score: 6529.5 bits: 1222.9 E(85289): 0
Smith-Waterman score: 20215; 100.0% identity (100.0% similar) in 3045 aa overlap (53-3097:14-3058)
30 40 50 60 70 80
pF1KE1 AAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDK
::::::::::::::::::::::::::::::
XP_011 MQTPGWRAEEGGPGFRKNDEMKAMDVLPILKEKVAYLSGGRDK
10 20 30 40
90 100 110 120 130 140
pF1KE1 RGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE1 KILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEF
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE1 DGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQ
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE1 LKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTR
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE1 QHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQT
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE1 QHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERST
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE1 LLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVS
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE1 QDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRL
470 480 490 500 510 520
570 580 590 600 610 620
pF1KE1 HQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYT
530 540 550 560 570 580
630 640 650 660 670 680
pF1KE1 NADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKE
590 600 610 620 630 640
690 700 710 720 730 740
pF1KE1 LWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSA
650 660 670 680 690 700
750 760 770 780 790 800
pF1KE1 ISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDL
710 720 730 740 750 760
810 820 830 840 850 860
pF1KE1 ESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQAS
770 780 790 800 810 820
870 880 890 900 910 920
pF1KE1 GVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGW
830 840 850 860 870 880
930 940 950 960 970 980
pF1KE1 IRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDM
890 900 910 920 930 940
990 1000 1010 1020 1030 1040
pF1KE1 DMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCG
950 960 970 980 990 1000
1050 1060 1070 1080 1090 1100
pF1KE1 GADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHI
1010 1020 1030 1040 1050 1060
1110 1120 1130 1140 1150 1160
pF1KE1 KAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYL
1070 1080 1090 1100 1110 1120
1170 1180 1190 1200 1210 1220
pF1KE1 STHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVT
1130 1140 1150 1160 1170 1180
1230 1240 1250 1260 1270 1280
pF1KE1 AVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHEL
1190 1200 1210 1220 1230 1240
1290 1300 1310 1320 1330 1340
pF1KE1 NEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFG
1250 1260 1270 1280 1290 1300
1350 1360 1370 1380 1390 1400
pF1KE1 NMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAG
1310 1320 1330 1340 1350 1360
1410 1420 1430 1440 1450 1460
pF1KE1 SYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPK
1370 1380 1390 1400 1410 1420
1470 1480 1490 1500 1510 1520
pF1KE1 RANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEV
1430 1440 1450 1460 1470 1480
1530 1540 1550 1560 1570 1580
pF1KE1 KDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDW
1490 1500 1510 1520 1530 1540
1590 1600 1610 1620 1630 1640
pF1KE1 IKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIAS
1550 1560 1570 1580 1590 1600
1650 1660 1670 1680 1690 1700
pF1KE1 RTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTD
1610 1620 1630 1640 1650 1660
1710 1720 1730 1740 1750 1760
pF1KE1 RSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQS
1670 1680 1690 1700 1710 1720
1770 1780 1790 1800 1810 1820
pF1KE1 SPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSA
1730 1740 1750 1760 1770 1780
1830 1840 1850 1860 1870 1880
pF1KE1 ATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQ
1790 1800 1810 1820 1830 1840
1890 1900 1910 1920 1930 1940
pF1KE1 PDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSF
1850 1860 1870 1880 1890 1900
1950 1960 1970 1980 1990 2000
pF1KE1 NPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKED
1910 1920 1930 1940 1950 1960
2010 2020 2030 2040 2050 2060
pF1KE1 GVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYC
1970 1980 1990 2000 2010 2020
2070 2080 2090 2100 2110 2120
pF1KE1 QNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKAS
2030 2040 2050 2060 2070 2080
2130 2140 2150 2160 2170 2180
pF1KE1 LDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPR
2090 2100 2110 2120 2130 2140
2190 2200 2210 2220 2230 2240
pF1KE1 CRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRT
2150 2160 2170 2180 2190 2200
2250 2260 2270 2280 2290 2300
pF1KE1 GDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGS
2210 2220 2230 2240 2250 2260
2310 2320 2330 2340 2350 2360
pF1KE1 GGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAE
2270 2280 2290 2300 2310 2320
2370 2380 2390 2400 2410 2420
pF1KE1 ADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGA
2330 2340 2350 2360 2370 2380
2430 2440 2450 2460 2470 2480
pF1KE1 ANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKG
2390 2400 2410 2420 2430 2440
2490 2500 2510 2520 2530 2540
pF1KE1 GSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQS
2450 2460 2470 2480 2490 2500
2550 2560 2570 2580 2590 2600
pF1KE1 NGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAA
2510 2520 2530 2540 2550 2560
2610 2620 2630 2640 2650 2660
pF1KE1 EGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKS
2570 2580 2590 2600 2610 2620
2670 2680 2690 2700 2710 2720
pF1KE1 REGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPE
2630 2640 2650 2660 2670 2680
2730 2740 2750 2760 2770 2780
pF1KE1 HNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMD
2690 2700 2710 2720 2730 2740
2790 2800 2810 2820 2830 2840
pF1KE1 GIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELG
2750 2760 2770 2780 2790 2800
2850 2860 2870 2880 2890 2900
pF1KE1 ILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEA
2810 2820 2830 2840 2850 2860
2910 2920 2930 2940 2950 2960
pF1KE1 VRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPE
2870 2880 2890 2900 2910 2920
2970 2980 2990 3000 3010 3020
pF1KE1 IILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQK
2930 2940 2950 2960 2970 2980
3030 3040 3050 3060 3070 3080
pF1KE1 AKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPI
2990 3000 3010 3020 3030 3040
3090
pF1KE1 RSIKNFLQSRLLPRV
:::::::::::::::
XP_011 RSIKNFLQSRLLPRV
3050
>>XP_011512409 (OMIM: 601893,617061) PREDICTED: triple f (3076 aa)
initn: 20207 init1: 20207 opt: 20207 Z-score: 6526.8 bits: 1222.4 E(85289): 0
Smith-Waterman score: 20207; 100.0% identity (100.0% similar) in 3044 aa overlap (54-3097:33-3076)
30 40 50 60 70 80
pF1KE1 AGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKR
::::::::::::::::::::::::::::::
XP_011 RRGLGRAARGCRSSCPSYLERIRWRAVWTWFRKNDEMKAMDVLPILKEKVAYLSGGRDKR
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE1 GGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLK
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE1 ILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFD
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE1 GCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQL
190 200 210 220 230 240
270 280 290 300 310 320
pF1KE1 KKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQ
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE1 HLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQ
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE1 HNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTL
370 380 390 400 410 420
450 460 470 480 490 500
pF1KE1 LDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQ
430 440 450 460 470 480
510 520 530 540 550 560
pF1KE1 DGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLH
490 500 510 520 530 540
570 580 590 600 610 620
pF1KE1 QRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTN
550 560 570 580 590 600
630 640 650 660 670 680
pF1KE1 ADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKEL
610 620 630 640 650 660
690 700 710 720 730 740
pF1KE1 WTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAI
670 680 690 700 710 720
750 760 770 780 790 800
pF1KE1 SSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLE
730 740 750 760 770 780
810 820 830 840 850 860
pF1KE1 SWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASG
790 800 810 820 830 840
870 880 890 900 910 920
pF1KE1 VELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWI
850 860 870 880 890 900
930 940 950 960 970 980
pF1KE1 RNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMD
910 920 930 940 950 960
990 1000 1010 1020 1030 1040
pF1KE1 MIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGG
970 980 990 1000 1010 1020
1050 1060 1070 1080 1090 1100
pF1KE1 ADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIK
1030 1040 1050 1060 1070 1080
1110 1120 1130 1140 1150 1160
pF1KE1 APEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLS
1090 1100 1110 1120 1130 1140
1170 1180 1190 1200 1210 1220
pF1KE1 THTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTA
1150 1160 1170 1180 1190 1200
1230 1240 1250 1260 1270 1280
pF1KE1 VDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELN
1210 1220 1230 1240 1250 1260
1290 1300 1310 1320 1330 1340
pF1KE1 EEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGN
1270 1280 1290 1300 1310 1320
1350 1360 1370 1380 1390 1400
pF1KE1 MQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGS
1330 1340 1350 1360 1370 1380
1410 1420 1430 1440 1450 1460
pF1KE1 YFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKR
1390 1400 1410 1420 1430 1440
1470 1480 1490 1500 1510 1520
pF1KE1 ANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVK
1450 1460 1470 1480 1490 1500
1530 1540 1550 1560 1570 1580
pF1KE1 DSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWI
1510 1520 1530 1540 1550 1560
1590 1600 1610 1620 1630 1640
pF1KE1 KHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASR
1570 1580 1590 1600 1610 1620
1650 1660 1670 1680 1690 1700
pF1KE1 TSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDR
1630 1640 1650 1660 1670 1680
1710 1720 1730 1740 1750 1760
pF1KE1 SPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSS
1690 1700 1710 1720 1730 1740
1770 1780 1790 1800 1810 1820
pF1KE1 PGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAA
1750 1760 1770 1780 1790 1800
1830 1840 1850 1860 1870 1880
pF1KE1 TPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQP
1810 1820 1830 1840 1850 1860
1890 1900 1910 1920 1930 1940
pF1KE1 DSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFN
1870 1880 1890 1900 1910 1920
1950 1960 1970 1980 1990 2000
pF1KE1 PSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDG
1930 1940 1950 1960 1970 1980
2010 2020 2030 2040 2050 2060
pF1KE1 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQ
1990 2000 2010 2020 2030 2040
2070 2080 2090 2100 2110 2120
pF1KE1 NKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASL
2050 2060 2070 2080 2090 2100
2130 2140 2150 2160 2170 2180
pF1KE1 DTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRC
2110 2120 2130 2140 2150 2160
2190 2200 2210 2220 2230 2240
pF1KE1 RERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTG
2170 2180 2190 2200 2210 2220
2250 2260 2270 2280 2290 2300
pF1KE1 DVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSG
2230 2240 2250 2260 2270 2280
2310 2320 2330 2340 2350 2360
pF1KE1 GGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEA
2290 2300 2310 2320 2330 2340
2370 2380 2390 2400 2410 2420
pF1KE1 DKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAA
2350 2360 2370 2380 2390 2400
2430 2440 2450 2460 2470 2480
pF1KE1 NASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGG
2410 2420 2430 2440 2450 2460
2490 2500 2510 2520 2530 2540
pF1KE1 SFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSN
2470 2480 2490 2500 2510 2520
2550 2560 2570 2580 2590 2600
pF1KE1 GSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAE
2530 2540 2550 2560 2570 2580
2610 2620 2630 2640 2650 2660
pF1KE1 GWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSR
2590 2600 2610 2620 2630 2640
2670 2680 2690 2700 2710 2720
pF1KE1 EGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEH
2650 2660 2670 2680 2690 2700
2730 2740 2750 2760 2770 2780
pF1KE1 NTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDG
2710 2720 2730 2740 2750 2760
2790 2800 2810 2820 2830 2840
pF1KE1 IMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGI
2770 2780 2790 2800 2810 2820
2850 2860 2870 2880 2890 2900
pF1KE1 LQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAV
2830 2840 2850 2860 2870 2880
2910 2920 2930 2940 2950 2960
pF1KE1 RYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEI
2890 2900 2910 2920 2930 2940
2970 2980 2990 3000 3010 3020
pF1KE1 ILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILGNPVSLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKA
2950 2960 2970 2980 2990 3000
3030 3040 3050 3060 3070 3080
pF1KE1 KEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEFVCFLLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIR
3010 3020 3030 3040 3050 3060
3090
pF1KE1 SIKNFLQSRLLPRV
::::::::::::::
XP_011 SIKNFLQSRLLPRV
3070
>>XP_011512412 (OMIM: 601893,617061) PREDICTED: triple f (3038 aa)
initn: 20165 init1: 20165 opt: 20165 Z-score: 6513.4 bits: 1219.9 E(85289): 0
Smith-Waterman score: 20165; 100.0% identity (100.0% similar) in 3038 aa overlap (60-3097:1-3038)
30 40 50 60 70 80
pF1KE1 GGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILT
::::::::::::::::::::::::::::::
XP_011 MKAMDVLPILKEKVAYLSGGRDKRGGPILT
10 20 30
90 100 110 120 130 140
pF1KE1 FPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESF
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE1 PCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYN
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE1 HEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIK
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE1 APIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMW
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE1 HVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAM
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE1 NCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE1 FHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE1 DKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLQRPLTPGSSDSLTASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLC
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE1 VFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLE
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE1 AAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEE
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE1 LQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTP
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE1 HNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNSSINHIETVLQQLDEAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDEL
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE1 SQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQMNDFDTEDLTIAEQRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCD
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE1 RDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDVDMATRVQDLLEFLHEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESM
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE1 LNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNAGLITASSLQEAEQLQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCA
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE1 EKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGP
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE1 NSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSETDHVTPMISKHLEQKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQV
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE1 KNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNILNELFQRENRVLHYWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTG
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE1 SSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIQHTQELLKEHEEFQITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYR
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE1 DFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELNEEKRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFSLRMEKYRTSLEKALGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELNEEKRKS
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE1 ARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARRKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYE
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE1 FHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQ
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE1 QRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMH
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500 1510 1520
pF1KE1 LSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMLEGFDENIESQGELILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRS
1420 1430 1440 1450 1460 1470
1530 1540 1550 1560 1570 1580
pF1KE1 KYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWIKHIREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYLYKSKLFTSELGVTEHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWIKHIREV
1480 1490 1500 1510 1520 1530
1590 1600 1610 1620 1630 1640
pF1KE1 IQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQERTIHLKGALKEPIHIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTL
1540 1550 1560 1570 1580 1590
1650 1660 1670 1680 1690 1700
pF1KE1 DSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSDKLSGGCELTVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEG
1600 1610 1620 1630 1640 1650
1710 1720 1730 1740 1750 1760
pF1KE1 LVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSSPGPKRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSSPGPKRP
1660 1670 1680 1690 1700 1710
1770 1780 1790 1800 1810 1820
pF1KE1 GNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNTLRKWLTSPVRRLSSGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDET
1720 1730 1740 1750 1760 1770
1830 1840 1850 1860 1870 1880
pF1KE1 VEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEERGRNEGLSSGTLSKSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDK
1780 1790 1800 1810 1820 1830
1890 1900 1910 1920 1930 1940
pF1KE1 ASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSRLLVRPTSSETPSAAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSL
1840 1850 1860 1870 1880 1890
1950 1960 1970 1980 1990 2000
pF1KE1 LSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSSSPIDEMEERKSSSLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMK
1900 1910 1920 1930 1940 1950
2010 2020 2030 2040 2050 2060
pF1KE1 GKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQNKPKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKDKIVFGNIHQIYDWHRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQNKPKSE
1960 1970 1980 1990 2000 2010
2070 2080 2090 2100 2110 2120
pF1KE1 HIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLDTSELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIVSEYIDTFFEDLKQRLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLDTSELE
2020 2030 2040 2050 2060 2070
2130 2140 2150 2160 2170 2180
pF1KE1 RAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCRERRIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAVEVMCIVPRRCNDMMNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCRERRIF
2080 2090 2100 2110 2120 2130
2190 2200 2210 2220 2230 2240
pF1KE1 LFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTGDVVETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFEQIVIFSEPLDKKKGFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTGDVVETF
2140 2150 2160 2170 2180 2190
2250 2260 2270 2280 2290 2300
pF1KE1 ILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSGGGGGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSGGGGGSG
2200 2210 2220 2230 2240 2250
2310 2320 2330 2340 2350 2360
pF1KE1 GGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGAPSGGSGHSGGPSSCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGT
2260 2270 2280 2290 2300 2310
2370 2380 2390 2400 2410 2420
pF1KE1 STPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSS
2320 2330 2340 2350 2360 2370
2430 2440 2450 2460 2470 2480
pF1KE1 PDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGGSFWSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGGSFWSSI
2380 2390 2400 2410 2420 2430
2490 2500 2510 2520 2530 2540
pF1KE1 PASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PASPASRPGSFTFPGDSDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSS
2440 2450 2460 2470 2480 2490
2550 2560 2570 2580 2590 2600
pF1KE1 SSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNISTMLVTHDYTAVKEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGF
2500 2510 2520 2530 2540 2550
2610 2620 2630 2640 2650 2660
pF1KE1 VLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGHTSAVIVENPDGTLKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNK
2560 2570 2580 2590 2600 2610
2670 2680 2690 2700 2710 2720
pF1KE1 VSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSVKLLNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNND
2620 2630 2640 2650 2660 2670
2730 2740 2750 2760 2770 2780
pF1KE1 GHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDGIMVTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHYSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDGIMVTWK
2680 2690 2700 2710 2720 2730
2790 2800 2810 2820 2830 2840
pF1KE1 DNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNFDSFYSEVAELGRGRFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQH
2740 2750 2760 2770 2780 2790
2850 2860 2870 2880 2890 2900
pF1KE1 PLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLVGLLDTFETPTSYILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNC
2800 2810 2820 2830 2840 2850
2910 2920 2930 2940 2950 2960
pF1KE1 RIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIAHLDLKPENILVDESLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPV
2860 2870 2880 2890 2900 2910
2970 2980 2990 3000 3010 3020
pF1KE1 SLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLTSDTWSVGVLTYVLLSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCF
2920 2930 2940 2950 2960 2970
3030 3040 3050 3060 3070 3080
pF1KE1 LLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQEDPAKRPSAALALQEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFL
2980 2990 3000 3010 3020 3030
3090
pF1KE1 QSRLLPRV
::::::::
XP_011 QSRLLPRV
>>XP_016865291 (OMIM: 601893,617061) PREDICTED: triple f (2880 aa)
initn: 19830 init1: 19041 opt: 19041 Z-score: 6151.8 bits: 1153.0 E(85289): 0
Smith-Waterman score: 19041; 100.0% identity (100.0% similar) in 2871 aa overlap (1-2871:1-2871)
10 20 30 40 50 60
pF1KE1 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKT
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE1 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE1 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE1 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE1 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE1 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLW
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE1 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE1 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELL
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE1 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE1 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE1 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE1 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE1 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE1 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLAHKH
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE1 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGEEEG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE1 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELVKSK
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE1 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQELVET
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE1 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKCLED
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE1 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLLIKP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE1 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGKIVA
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE1 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNSIKV
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE1 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNAL
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE1 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPSR
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE1 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAE
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE1 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSP
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE1 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGDSDSLQRQTPRHAAPG
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE1 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQGEVVQI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE1 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGTLKKSTSWHTALRLRK
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE1 KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPPEFVIPLSEVTCETGE
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE1 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLKIVGVTTEDDGIYTCI
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KE1 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRGRFSVVKKCDQKGTKR
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KE1 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMADQGRLLDC
::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 AVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEILRISWWMRV
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KE1 VVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTIKLADFGDA
>>XP_016865292 (OMIM: 601893,617061) PREDICTED: triple f (2612 aa)
initn: 17213 init1: 17213 opt: 17213 Z-score: 5563.8 bits: 1044.0 E(85289): 0
Smith-Waterman score: 17213; 99.8% identity (100.0% similar) in 2602 aa overlap (496-3097:11-2612)
470 480 490 500 510 520
pF1KE1 KACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLT
....::::::::::::::::::::::::::
XP_016 MGKYLSLGTHMTFQEVSQDGKSLLDKLQRPLTPGSSDSLT
10 20 30 40
530 540 550 560 570 580
pF1KE1 ASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASANYSKAVHHVLDVIHEVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENH
50 60 70 80 90 100
590 600 610 620 630 640
pF1KE1 GEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEAFLSKHTGVGKSLHRARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEI
110 120 130 140 150 160
650 660 670 680 690 700
pF1KE1 YQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQAAHQLEDRIQDFVRRVEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEA
170 180 190 200 210 220
710 720 730 740 750 760
pF1KE1 VQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLD
230 240 250 260 270 280
770 780 790 800 810 820
pF1KE1 EAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQSQMEELFQERKIKLELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAE
290 300 310 320 330 340
830 840 850 860 870 880
pF1KE1 QRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRLQHHADKALTMNNLTFDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFL
350 360 370 380 390 400
890 900 910 920 930 940
pF1KE1 HEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEKQQELDLAAEQHRKHLEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQ
410 420 430 440 450 460
950 960 970 980 990 1000
pF1KE1 LQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQREHEQFQHAIEKTHQSALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMED
470 480 490 500 510 520
1010 1020 1030 1040 1050 1060
pF1KE1 RLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLKLVNASVAFYKTSEQVCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLE
530 540 550 560 570 580
1070 1080 1090 1100 1110 1120
pF1KE1 QKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEAFLKACTLARRNADVFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLH
590 600 610 620 630 640
1130 1140 1150 1160 1170 1180
pF1KE1 YWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YWTMRKRRLDQCQQYVVFERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEF
650 660 670 680 690 700
1190 1200 1210 1220 1230 1240
pF1KE1 QITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QITAKQTKERVKLLIQLADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKA
710 720 730 740 750 760
1250 1260 1270 1280 1290 1300
pF1KE1 LGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGISSDSNKSSKSLQLDIIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEK
770 780 790 800 810 820
1310 1320 1330 1340 1350 1360
pF1KE1 AYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQL
830 840 850 860 870 880
1370 1380 1390 1400 1410 1420
pF1KE1 PEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEDVGHCFVTWADKFQMYVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKP
890 900 910 920 930 940
1430 1440 1450 1460 1470 1480
pF1KE1 VQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQRITKYQLLLKELLTCCEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGE
950 960 970 980 990 1000
1490 1500 1510 1520 1530 1540
pF1KE1 LILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILQESFQVWDPKTLIRKGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVT
1010 1020 1030 1040 1050 1060
1550 1560 1570 1580 1590 1600
pF1KE1 EHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHVEGDPCKFALWVGRTPTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPI
1070 1080 1090 1100 1110 1120
1610 1620 1630 1640 1650 1660
pF1KE1 HIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIPKTAPATRQKGRRDGEDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIH
1130 1140 1150 1160 1170 1180
1670 1680 1690 1700 1710 1720
pF1KE1 DFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSM
1190 1200 1210 1220 1230 1240
1730 1740 1750 1760 1770 1780
pF1KE1 EMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEGIFNHKDSLSVSSNDASPPASVASLQPHMIGAQSSPGPKRPGNTLRKWLTSPVRRLS
1250 1260 1270 1280 1290 1300
1790 1800 1810 1820 1830 1840
pF1KE1 SGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGKADGHVKKLAHKHKKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLS
1310 1320 1330 1340 1350 1360
1850 1860 1870 1880 1890 1900
pF1KE1 KSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSSSSGMQSCGEEEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPS
1370 1380 1390 1400 1410 1420
1910 1920 1930 1940 1950 1960
pF1KE1 AAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAELVSAIEELVKSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSS
1430 1440 1450 1460 1470 1480
1970 1980 1990 2000 2010 2020
pF1KE1 SLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDW
1490 1500 1510 1520 1530 1540
2030 2040 2050 2060 2070 2080
pF1KE1 HRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRDFFLGELEKCLEDPEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQ
1550 1560 1570 1580 1590 1600
2090 2100 2110 2120 2130 2140
pF1KE1 RLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLGHRLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDM
1610 1620 1630 1640 1650 1660
2150 2160 2170 2180 2190 2200
pF1KE1 MNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNVGRLQGFDGKIVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKK
1670 1680 1690 1700 1710 1720
2210 2220 2230 2240 2250 2260
pF1KE1 GFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSMPGFLFKNSIKVSCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHE
1730 1740 1750 1760 1770 1780
2270 2280 2290 2300 2310 2320
pF1KE1 INQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INQILENQRNFLNALTSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPS
1790 1800 1810 1820 1830 1840
2330 2340 2350 2360 2370 2380
pF1KE1 SCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCGGAPSTSRSRPSRIPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEA
1850 1860 1870 1880 1890 1900
2390 2400 2410 2420 2430 2440
pF1KE1 GPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLP
1910 1920 1930 1940 1950 1960
2450 2460 2470 2480 2490 2500
pF1KE1 LGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGKPRAGAASPLNSPLSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTFPGD
1970 1980 1990 2000 2010 2020
2510 2520 2530 2540 2550 2560
pF1KE1 SDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDSLQRQTPRHAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAV
2030 2040 2050 2060 2070 2080
2570 2580 2590 2600 2610 2620
pF1KE1 KEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEDEINVYQGEVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGHTSAVIVENPDGT
2090 2100 2110 2120 2130 2140
2630 2640 2650 2660 2670 2680
pF1KE1 LKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKSTSWHTALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNKVSVKLLNPNYIYDVPP
2150 2160 2170 2180 2190 2200
2690 2700 2710 2720 2730 2740
pF1KE1 EFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGHYSISYSDLGEATLK
2210 2220 2230 2240 2250 2260
2750 2760 2770 2780 2790 2800
pF1KE1 IVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVGVTTEDDGIYTCIAVNDMGSASSSASLRVLGPGMDGIMVTWKDNFDSFYSEVAELGRG
2270 2280 2290 2300 2310 2320
2810 2820 2830 2840 2850 2860
pF1KE1 RFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFSVVKKCDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSY
2330 2340 2350 2360 2370 2380
2870 2880 2890 2900 2910 2920
pF1KE1 ILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVLEMADQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDE
2390 2400 2410 2420 2430 2440
2930 2940 2950 2960 2970 2980
pF1KE1 SLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLAKPTIKLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVL
2450 2460 2470 2480 2490 2500
2990 3000 3010 3020 3030 3040
pF1KE1 LSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGVSPFLDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALAL
2510 2520 2530 2540 2550 2560
3050 3060 3070 3080 3090
pF1KE1 QEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEQWLQAGNGRSTGVLDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
2570 2580 2590 2600 2610
>>XP_006713876 (OMIM: 604605,608901) PREDICTED: kalirin (2966 aa)
initn: 9268 init1: 6479 opt: 9432 Z-score: 3057.9 bits: 580.5 E(85289): 1.4e-163
Smith-Waterman score: 12660; 62.1% identity (79.9% similar) in 3192 aa overlap (34-3093:5-2962)
10 20 30 40 50 60
pF1KE1 SSGGAAAPAASSGPAAAASAAGSGCGGGAGEGA-EEAAKDLADIAAFFRSGFRKNDEMKA
::: ::.. .:. ::::.: .:: .::
XP_006 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKA
10 20 30
70 80 90 100 110 120
pF1KE1 MDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKR
:::::::::::..:::::::::::::::::::::::::::::.:..::: .:::.::::
XP_006 SDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 GFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETN
:::::.:::::::: :::::: :::.:: ::::::::::::::::.:::::::: :::.
XP_006 GFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 MVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILA
:::.:::::.::::::: :::: :.::::::::.:...:.....:.:.:::::.::..::
XP_006 MVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 KKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNA
.::.: :.::.: .:.::.::::::.:::.:.:: :::.::: :. :..: .: :.:
XP_006 RKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 DLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGL
:.:.:.::....::.:::::::::::::::::::::::::::::::::::::::.::: :
XP_006 DFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKEL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 FLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQI
::.:.::::.:. .:..::::::::::: ::.:::::::::::.:: :.::::::::.::
XP_006 FLQSHTEIGVSYQYALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 ASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLED
..::.::::.::::::::::.: ::..::::::...:.::.::: :.: ::::.::::
XP_006 STQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLEL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 AIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIH
:::::: .::..: ::.:::::::.::: :::::.::.:.::::.::::::::.::::.:
XP_006 AIHHHQTLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVH
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 EVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHR
:::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 ARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRR
::::::::.:::::::::::::::::::::::::::::::::::.::..:: ::::::::
XP_006 ARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 VEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQ
:::::.:::::::::::.::::::.:.::::.:.:: :.::.:::.:::.: ::: .::.
XP_006 VEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLD
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE1 VTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKL
.:.:::::::::::::::::.:.:::::.:::.:::.::::::.:: ::::::.::::::
XP_006 ATLNVIKEGEDLIQQLRDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE1 ELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLT
..::::::::. .:.. ..:..::..: .:::::.:::::.::::::.:... :.:::.:
XP_006 DIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE1 FDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKH
:.::.::::: ::..::::::.::.:..:.:.:..::.:::::::::.::.: ::: .:.
XP_006 FEVIQQGQDLHQYITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKR
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE1 LEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQ
::::.:::::::::::::::::::::::::.:..::::.::::::::::::: :::::::
XP_006 LEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQ
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE1 SALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQ
::::::::::..:::.::: : ::.:::::: ::::::::::::::::::::::::::::
XP_006 SALQVQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQ
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE1 VCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNAD
::::::::::::.:.:::::: ::::: .: ::: :.::::::::::::::::::::::.
XP_006 VCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAE
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE1 VFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVV
:::::.:::.:.::....: ..:::::: ::.::.::::::::.::..::::::::::::
XP_006 VFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVV
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE1 FERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQL
:::::::::.::...:::::::::::: . ..:::::::. ::.. ::::::.:::::::
XP_006 FERSAKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQL
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE1 ADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLD
::.: :::: ::.::.: ::.:::.:::::::: ::: :::::::.....:: .:.::
XP_006 ADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNK---DLELD
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE1 IIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEM
:::::. ::::::: ::.:::::::::.::::::::.::::::::::.::..::::::
XP_006 IIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEM
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE1 TSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQM
:::::::::::.::: :::::.::::.:::::::::::::::::::::::::::::::::
XP_006 TSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQM
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE1 YVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTC
:::::::::::.::::::::..::::::::::::::::::::::::::::::::::::::
XP_006 YVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTC
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE1 CEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIR
:::::::.::::::::::::.::::::.:::::::::.. :::::::..:::::::.:::
XP_006 CEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIR
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE1 KGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRT
:::::::::::.:::::::.:::::..::.::.::.:::::::::::::::::::: :::
XP_006 KGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRT
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE1 PTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDG
:.:::: :::::.::.::.:::.:::::::: ::::::::::...::: :....:::
XP_006 PSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDG
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE1 -EDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQ
::.:::::::::::::::::::::::.::::::::::::::..::.: .:.::::. ::
XP_006 VEDIDSQGDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGHSSELTIQVGQ
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730
pF1KE1 TVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNH-KDSLS-V
:::.:::: ..: :::::::.::: ::::: ..:::.:::::.::. .: ::. :
XP_006 TVELLERPSERPGWCLVRTTERSPPLEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHS
1660 1670 1680 1690 1700 1710
1740 1750 1760 1770 1780 1790
pF1KE1 SSNDASPPASVASLQ--PHMIGAQSSPGPKRPGNTLRKWLTSPVRRLSSGKADGHVKKLA
::.... :::.:: : . . .::::::: :::.::::::::::.::::::..::
XP_006 SSENGGKSESVANLQAQPSLNSIHSSPGPKRSTNTLKKWLTSPVRRLNSGKADGNIKK--
1720 1730 1740 1750 1760
1800 1810 1820 1830 1840 1850
pF1KE1 HKHKKSREVRKSADAGSQKDSDDSAATPQDETVEERGRNEGLSSGTLSKSSSSGMQSCGE
.:: :. ::: : :: : .:.. ::: ....:. :..: ::
XP_006 --QKKVRDGRKSFDLGSPKPGDET--TPQGDSADEK--------------SKKGW---GE
1770 1780 1790 1800
1860 1870 1880 1890 1900 1910
pF1KE1 EEGEEGADAVPLPPPMAIQQHSLLQPDSQDDKASSRLLVRPTSSETPSAAELVSAIEELV
.: .: . .:::::: : ... : .::. .:: : .: .:.:.:.::.::.:::.::
XP_006 DEPDE-ESHTPLPPPMKIFDND---P-TQDEMSSSLLAARQASTEVPTAADLVNAIEKLV
1810 1820 1830 1840 1850 1860
1920 1930 1940 1950 1960 1970
pF1KE1 KSKMALEDRPSSLLVDQGDSSSPSFNPSDNSLLSSSSPIDEMEERKSSSLKRRHYVLQEL
:.:..:: :: .:. ..:. . .... . : . ::.:...:. : .::.::
XP_006 KNKLSLEG--SSY---RGSLKDPA-GCLNEGMAPPTPPKNPEEEQKAKALRGRMFVLNEL
1870 1880 1890 1900 1910
1980 1990 2000 2010 2020 2030
pF1KE1 VETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWHRDFFLGELEKC
:.::.:::.::: ::::.: ..: :::.::.:::::::::::::::::.::::.:::::
XP_006 VQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDFFLAELEKC
1920 1930 1940 1950 1960 1970
2040 2050 2060 2070 2080 2090
pF1KE1 LEDPEKLGSLFVKHERRLHMYIAYCQNKPKSEHIVSEYIDTFFEDLKQRLGHRLQLTDLL
... ..:..::.::::.::.:. ::::::.::.::.:: :..::..::....:: :.:.:
XP_006 IQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEY-DAYFEEVKQEINQRLTLSDFL
1980 1990 2000 2010 2020 2030
2100 2110 2120 2130 2140 2150
pF1KE1 IKPVQRIMKYQLLLKDFLKYSKKASLDTSELERAVEVMCIVPRRCNDMMNVGRLQGFDGK
:::.::: ::::::::::.::.::.:. :..:.:::.::.::.:::::::.::::::.:
XP_006 IKPIQRITKYQLLLKDFLRYSEKAGLECSDIEKAVELMCLVPKRCNDMMNLGRLQGFEGT
2040 2050 2060 2070 2080 2090
2160 2170 2180 2190 2200 2210
pF1KE1 IVAQGKLLLQDTFLVTDQDAGLLPRCRERRIFLFEQIVIFSEPLDKKKGFSMPGFLFKNS
..:::::: :::: : . :::. : .:::.::::::::::: : .:: ::..:: :
XP_006 LTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELL--RKGSLTPGYMFKRS
2100 2110 2120 2130 2140 2150
2220 2230 2240 2250 2260 2270
pF1KE1 IKVSCLCLEENVENDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFL
::.. : :::::.:::::::: .: .. : .:.... ...:.:...:::.::.::.::
XP_006 IKMNYLVLEENVDNDPCKFALMNR--ETSERVVLQAANADIQQAWVQDINQVLETQRDFL
2160 2170 2180 2190 2200 2210
2280 2290 2300 2310 2320 2330
pF1KE1 NALTSPIEYQRNHSGGGGGGGSGGSGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSR
::: :::::::.. . .. ::.
XP_006 NALQSPIEYQRKER--------------------------------------STAVMRSQ
2220 2230
2340 2350 2360 2370 2380 2390
pF1KE1 PSRIPQPVRHHPPVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGA
:.:.:: :.:. :.:.
XP_006 PARLPQ-------------------------------------ASPRPYSSVPA------
2240 2250
2400 2410 2420 2430 2440 2450
pF1KE1 DAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDARASLGTLPLGKPRAGAASPL
:::. : ::
XP_006 ---GSEK-------------PPKG------------------------------------
2460 2470 2480 2490 2500 2510
pF1KE1 NSPLSSAVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFTF--PGDSDSLQRQTPR
:: : :.:: . ..:: :: : . :::. ..:
XP_006 ----SSYNP-----PLPPLKISTSNGS------------PG-FEYHQPGDKFEASKQ---
2260 2270 2280 2290
2520 2530 2540 2550 2560 2570
pF1KE1 HAAPGKDTDRMSTCSSASEQSVQSTQSNGSESSSSSNISTMLVTHDYTAVKEDEINVYQG
. .. : ::. :.: : .:: :.::.:: : ::
XP_006 --------NDLGGC-------------NGT--------SSMAVIKDYYALKENEICVSQG
2300 2310 2320
2580 2590 2600 2610 2620 2630
pF1KE1 EVVQILASNQQNMFLVFRAATDQCPAAEGWIPGFVLGH-TSAVIVENPDGTLKKSTSWHT
::::.:: ::::: ::.. :.:. ::::::.:: .:. :.:. .:. ::..::: ::::
XP_006 EVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSDGSIKKSCSWHT
2330 2340 2350 2360 2370 2380
2640 2650 2660 2670
pF1KE1 ALRLRKKSEKKDKDGKREGKLENGYRKSREGLSNKVSVK--------------------L
::.::..: .. :: :. .: :: .. :.:::::: .
XP_006 -LRMRKRAEVENT-GKNEA---TGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI
2390 2400 2410 2420 2430 2440
2680 2690 2700 2710 2720 2730
pF1KE1 LNPNYIYDVPPEFVIPLSEVTCETGETVVLRCRVCGRPKASITWKGPEHNTLNNDGH---
::::.: .: :::..:: .::: :.::.:.:.:::::: .::::::..: :..:.
XP_006 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT
2450 2460 2470 2480 2490 2500
2740 2750 2760 2770
pF1KE1 YSISYSDLGEATLKIVGVTTEDDGIYTCIAVNDMGSASSSASLRVLG-------------
:..: : :: :::: .. .:.:::::::.:: :..:.::...: :
XP_006 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER
2510 2520 2530 2540 2550 2560
2780
pF1KE1 -----------------------------------------------------PG-----
::
XP_006 SCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQF
2570 2580 2590 2600 2610 2620
2790 2800 2810
pF1KE1 ----------------------------MDGIMVTWKDNFDSFYSEVAELGRGRFSVVKK
:: ..::.:::: :.:. :.::::::.:::
XP_006 RVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKK
2630 2640 2650 2660 2670 2680
2820 2830 2840 2850 2860 2870
pF1KE1 CDQKGTKRAVATKFVNKKLMKRDQVTHELGILQSLQHPLLVGLLDTFETPTSYILVLEMA
: .:.:.. ::.:::.::. :..:..:: ..:: :::: . : ::.:.::::::.::.
XP_006 CIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELM
2690 2700 2710 2720 2730 2740
2880 2890 2900 2910 2920 2930
pF1KE1 DQGRLLDCVVRWGSLTEGKIRAHLGEVLEAVRYLHNCRIAHLDLKPENILVDESLAKPTI
:.::::: .. : : :. .. ...::..::::::.::::.::::.:.: . : .
XP_006 DDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRV
2750 2760 2770 2780 2790 2800
2940 2950 2960 2970 2980 2990
pF1KE1 KLADFGDAVQLNTTYYIHQLLGNPEFAAPEIILGNPVSLTSDTWSVGVLTYVLLSGVSPF
:: :. ::::.. ..::.:::::::::::.: : :::: .: ::.::::::.:::::::
XP_006 KLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPF
2810 2820 2830 2840 2850 2860
3000 3010 3020 3030 3040 3050
pF1KE1 LDDSVEETCLNICRLDFSFPDDYFKGVSQKAKEFVCFLLQEDPAKRPSAALALQEQWLQA
::.: ::::.:.::.::::: .:: :::. :..:. .:::: .::.:: ::. :::
XP_006 LDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQP
2870 2880 2890 2900 2910 2920
3060 3070 3080 3090
pF1KE1 GNGRSTGV-LDTSRLTSFIERRKHQNDVRPIRSIKNFLQSRLLPRV
:: . . ::::::. :::::::::::::: ..:... .:.
XP_006 HNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT
2930 2940 2950 2960
>>XP_016862924 (OMIM: 604605,608901) PREDICTED: kalirin (1643 aa)
initn: 6975 init1: 6479 opt: 8769 Z-score: 2847.6 bits: 540.8 E(85289): 7.1e-152
Smith-Waterman score: 8769; 79.0% identity (94.6% similar) in 1622 aa overlap (34-1653:5-1623)
10 20 30 40 50 60
pF1KE1 SSGGAAAPAASSGPAAAASAAGSGCGGGAGEGA-EEAAKDLADIAAFFRSGFRKNDEMKA
::: ::.. .:. ::::.: .:: .::
XP_016 MNPPEGAAEEGGAADSDVDAFFRTGSFRNDGLKA
10 20 30
70 80 90 100 110 120
pF1KE1 MDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKR
:::::::::::..:::::::::::::::::::::::::::::.:..::: .:::.::::
XP_016 SDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE1 GFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETN
:::::.:::::::: :::::: :::.:: ::::::::::::::::.:::::::: :::.
XP_016 GFTVIIDMRGSKWDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE1 MVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILA
:::.:::::.::::::: :::: :.::::::::.:...:.....:.:.:::::.::..::
XP_016 MVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE1 KKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNA
.::.: :.::.: .:.::.::::::.:::.:.:: :::.::: :. :..: .: :.:
XP_016 RKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRNCIPGSA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE1 DLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGL
:.:.:.::....::.:::::::::::::::::::::::::::::::::::::::.::: :
XP_016 DFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKEL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE1 FLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQI
::.:.::::.:. .:..::::::::::: ::.:::::::::::.:: :.::::::::.::
XP_016 FLQSHTEIGVSYQYALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQI
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE1 ASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLED
..::.::::.::::::::::.: ::..::::::...:.::.::: :.: ::::.::::
XP_016 STQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGGLPSEMQDLEL
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE1 AIHHHQGIYEHITLAYSEVSQDGKSLLDKLQRPLTPGSSDSLTASANYSKAVHHVLDVIH
:::::: .::..: ::.:::::::.::: :::::.::.:.::::.::::::::.::::.:
XP_016 AIHHHQTLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNSESLTATANYSKAVHQVLDVVH
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE1 EVLHHQRQLENIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHR
:::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHR
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE1 ARALQKRHEDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRR
::::::::.:::::::::::::::::::::::::::::::::::.::..:: ::::::::
XP_016 ARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE1 VEQRKILLDMSVSFHTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQ
:::::.:::::::::::.::::::.:.::::.:.:: :.::.:::.:::.: ::: .::.
XP_016 VEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADSVDAVQELIKQFQQQQTATLD
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE1 VTVNVIKEGEDLIQQLRDSAISSNKTPHNSSINHIETVLQQLDEAQSQMEELFQERKIKL
.:.:::::::::::::::::.:.:::::.:::.:::.::::::.:: ::::::.::::::
XP_016 ATLNVIKEGEDLIQQLRDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE1 ELFLQLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQHHADKALTMNNLT
..::::::::. .:.. ..:..::..: .:::::.:::::.::::::.:... :.:::.:
XP_016 DIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE1 FDVIHQGQDLLQYVNEVQASGVELLCDRDVDMATRVQDLLEFLHEKQQELDLAAEQHRKH
:.::.::::: ::..::::::.::.:..:.:.:..::.:::::::::.::.: ::: .:.
XP_016 FEVIQQGQDLHQYITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKR
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE1 LEQCVQLRHLQAEVKQVLGWIRNGESMLNAGLITASSLQEAEQLQREHEQFQHAIEKTHQ
::::.:::::::::::::::::::::::::.:..::::.::::::::::::: :::::::
XP_016 LEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIEKTHQ
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE1 SALQVQQKAEAMLQANHYDMDMIRDCAEKVASHWQQLMLKMEDRLKLVNASVAFYKTSEQ
::::::::::..:::.::: : ::.:::::: ::::::::::::::::::::::::::::
XP_016 SALQVQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQ
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE1 VCSVLESLEQEYKREEDWCGGADKLGPNSETDHVTPMISKHLEQKEAFLKACTLARRNAD
::::::::::::.:.:::::: ::::: .: ::: :.::::::::::::::::::::::.
XP_016 VCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAE
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE1 VFLKYLHRNSVNMPGMVTHIKAPEQQVKNILNELFQRENRVLHYWTMRKRRLDQCQQYVV
:::::.:::.:.::....: ..:::::: ::.::.::::::::.::..::::::::::::
XP_016 VFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVV
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE1 FERSAKQALEWIHDNGEFYLSTHTSTGSSIQHTQELLKEHEEFQITAKQTKERVKLLIQL
:::::::::.::...:::::::::::: . ..:::::::. ::.. ::::::.:::::::
XP_016 FERSAKQALDWIQETGEFYLSTHTSTGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQL
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE1 ADGFCEKGHAHAAEIKKCVTAVDKRYRDFSLRMEKYRTSLEKALGISSDSNKSSKSLQLD
::.: :::: ::.::.: ::.:::.:::::::: ::: :::::::.....:: .:.::
XP_016 ADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTEDNK---DLELD
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE1 IIPASIPGSEVKLRDAAHELNEEKRKSARRKEFIMAELIQTEKAYVRDLRECMDTYLWEM
:::::. ::::::: ::.:::::::::.::::::::.::::::::::.::..::::::
XP_016 IIPASLSDREVKLRDANHEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEM
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE1 TSGVEEIPPGIVNKELIIFGNMQEIYEFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQM
:::::::::::.::: :::::.::::.:::::::::::::::::::::::::::::::::
XP_016 TSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQM
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE1 YVTYCKNKPDSTQLILEHAGSYFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTC
:::::::::::.::::::::..::::::::::::::::::::::::::::::::::::::
XP_016 YVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTC
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE1 CEEGKGEIKDGLEVMLSVPKRANDAMHLSMLEGFDENIESQGELILQESFQVWDPKTLIR
:::::::.::::::::::::.::::::.:::::::::.. :::::::..:::::::.:::
XP_016 CEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIR
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE1 KGRERHLFLFEMSLVFSKEVKDSSGRSKYLYKSKLFTSELGVTEHVEGDPCKFALWVGRT
:::::::::::.:::::::.:::::..::.::.::.:::::::::::::::::::: :::
XP_016 KGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRT
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE1 PTSDNKIVLKASSIENKQDWIKHIREVIQERTIHLKGALKEPIHIPKTAPATRQKGRRDG
:.:::: :::::.::.::.:::.:::::::: ::::::::::...::: :....:::
XP_016 PSSDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDG
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE1 -EDLDSQGDGSSQPDTISIASRTSQNTLDSDKLSGGCELTVVIHDFTACNSNELTIRRGQ
::.:::::::::::::::::::::::.::::
XP_016 VEDIDSQGDGSSQPDTISIASRTSQNTVDSDKDGNLVPRWHLGPGDPFSTYV
1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KE1 TVEVLERPHDKPDWCLVRTTDRSPAAEGLVPCGSLCIAHSRSSMEMEGIFNHKDSLSVSS
3097 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:17:25 2016 done: Sun Nov 6 17:17:29 2016
Total Scan time: 24.930 Total Display time: 2.640
Function used was FASTA [36.3.4 Apr, 2011]