Result of FASTA (omim) for
pF1KE1589
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1589, 1052 aa
1>>>pF1KE1589 1052 - 1052 aa - 1052 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2016+/-0.000506; mu= 2.9119+/- 0.031
mean_var=623.0868+/-139.479, 0's: 0 Z-trim(120.0): 1337 B-trim: 2130 in 1/53
Lambda= 0.051381
statistics sampled from 33989 (36123) to 33989 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.391), width: 16
Scan time: 7.770
The best scores are: opt bits E(92320)
NP_722560 (OMIM: 600758) focal adhesion kinase 1 i (1052) 7054 539.7 3.6e-152
NP_001339623 (OMIM: 600758) focal adhesion kinase (1052) 7054 539.7 3.6e-152
NP_005598 (OMIM: 600758) focal adhesion kinase 1 i (1074) 7054 539.7 3.6e-152
XP_024302973 (OMIM: 600758) focal adhesion kinase (1103) 7054 539.7 3.6e-152
NP_001339649 (OMIM: 600758) focal adhesion kinase (1055) 7038 538.5 8.1e-152
NP_001339648 (OMIM: 600758) focal adhesion kinase (1055) 7038 538.5 8.1e-152
NP_001339647 (OMIM: 600758) focal adhesion kinase (1055) 7038 538.5 8.1e-152
XP_016869146 (OMIM: 600758) focal adhesion kinase (1099) 7038 538.5 8.3e-152
XP_024302972 (OMIM: 600758) focal adhesion kinase (1106) 7038 538.5 8.3e-152
NP_001339646 (OMIM: 600758) focal adhesion kinase (1058) 7032 538.0 1.1e-151
XP_024302971 (OMIM: 600758) focal adhesion kinase (1109) 7032 538.1 1.1e-151
XP_016869158 (OMIM: 600758) focal adhesion kinase (1059) 7025 537.5 1.6e-151
XP_016869145 (OMIM: 600758) focal adhesion kinase (1103) 7025 537.6 1.6e-151
XP_024302970 (OMIM: 600758) focal adhesion kinase (1110) 7025 537.6 1.6e-151
XP_016869153 (OMIM: 600758) focal adhesion kinase (1061) 7016 536.9 2.5e-151
NP_001339644 (OMIM: 600758) focal adhesion kinase (1061) 7016 536.9 2.5e-151
XP_024302969 (OMIM: 600758) focal adhesion kinase (1112) 7016 536.9 2.6e-151
NP_001339642 (OMIM: 600758) focal adhesion kinase (1062) 7009 536.3 3.6e-151
NP_001339643 (OMIM: 600758) focal adhesion kinase (1062) 7009 536.3 3.6e-151
XP_016869143 (OMIM: 600758) focal adhesion kinase (1106) 7009 536.4 3.7e-151
XP_024302968 (OMIM: 600758) focal adhesion kinase (1113) 7009 536.4 3.7e-151
NP_001339665 (OMIM: 600758) focal adhesion kinase ( 960) 6328 485.8 5.4e-136
NP_001339645 (OMIM: 600758) focal adhesion kinase (1060) 6323 485.5 7.3e-136
NP_001339670 (OMIM: 600758) focal adhesion kinase ( 942) 6209 477.0 2.4e-133
XP_024302980 (OMIM: 600758) focal adhesion kinase ( 942) 6209 477.0 2.4e-133
NP_001339669 (OMIM: 600758) focal adhesion kinase ( 948) 6187 475.3 7.5e-133
XP_016869173 (OMIM: 600758) focal adhesion kinase ( 949) 6180 474.8 1.1e-132
NP_001339668 (OMIM: 600758) focal adhesion kinase ( 949) 6180 474.8 1.1e-132
NP_001186578 (OMIM: 600758) focal adhesion kinase (1065) 5901 454.2 1.9e-126
NP_001339654 (OMIM: 600758) focal adhesion kinase (1034) 5621 433.4 3.3e-120
XP_024302975 (OMIM: 600758) focal adhesion kinase (1085) 5621 433.5 3.4e-120
NP_001339657 (OMIM: 600758) focal adhesion kinase (1016) 4884 378.8 9.2e-104
XP_016869155 (OMIM: 600758) focal adhesion kinase (1060) 4884 378.8 9.4e-104
NP_001339674 (OMIM: 600758) focal adhesion kinase ( 913) 4839 375.4 8.8e-103
XP_024302977 (OMIM: 600758) focal adhesion kinase (1077) 4839 375.5 9.6e-103
NP_001339671 (OMIM: 600758) focal adhesion kinase ( 934) 4694 364.7 1.5e-99
NP_001339666 (OMIM: 600758) focal adhesion kinase ( 973) 4460 347.3 2.6e-94
NP_001339662 (OMIM: 600758) focal adhesion kinase ( 976) 4444 346.2 5.9e-94
NP_001339633 (OMIM: 600758) focal adhesion kinase (1089) 4444 346.2 6.3e-94
NP_001339661 (OMIM: 600758) focal adhesion kinase ( 980) 4431 345.2 1.2e-93
NP_001339641 (OMIM: 600758) focal adhesion kinase (1093) 4431 345.3 1.2e-93
NP_001339664 (OMIM: 600758) focal adhesion kinase ( 962) 4415 344.0 2.6e-93
NP_001339659 (OMIM: 600758) focal adhesion kinase ( 983) 4415 344.0 2.6e-93
NP_001339629 (OMIM: 600758) focal adhesion kinase (1096) 4415 344.1 2.8e-93
NP_001339628 (OMIM: 600758) focal adhesion kinase (1096) 4415 344.1 2.8e-93
NP_001339630 (OMIM: 600758) focal adhesion kinase (1096) 4415 344.1 2.8e-93
NP_001339631 (OMIM: 600758) focal adhesion kinase (1096) 4415 344.1 2.8e-93
NP_001339632 (OMIM: 600758) focal adhesion kinase (1096) 4415 344.1 2.8e-93
NP_001339627 (OMIM: 600758) focal adhesion kinase (1109) 4415 344.1 2.8e-93
NP_001339675 (OMIM: 600758) focal adhesion kinase ( 898) 4411 343.7 3.1e-93
>>NP_722560 (OMIM: 600758) focal adhesion kinase 1 isofo (1052 aa)
initn: 7054 init1: 7054 opt: 7054 Z-score: 2853.6 bits: 539.7 E(92320): 3.6e-152
Smith-Waterman score: 7054; 100.0% identity (100.0% similar) in 1052 aa overlap (1-1052:1-1052)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 GVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 GVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_722 LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE1 LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
::::::::::::::::::::::::::::::::
NP_722 LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
>>NP_001339623 (OMIM: 600758) focal adhesion kinase 1 is (1052 aa)
initn: 7054 init1: 7054 opt: 7054 Z-score: 2853.6 bits: 539.7 E(92320): 3.6e-152
Smith-Waterman score: 7054; 100.0% identity (100.0% similar) in 1052 aa overlap (1-1052:1-1052)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE1 GVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE1 LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
970 980 990 1000 1010 1020
1030 1040 1050
pF1KE1 LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
::::::::::::::::::::::::::::::::
NP_001 LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
>>NP_005598 (OMIM: 600758) focal adhesion kinase 1 isofo (1074 aa)
initn: 7054 init1: 7054 opt: 7054 Z-score: 2853.6 bits: 539.7 E(92320): 3.6e-152
Smith-Waterman score: 7054; 100.0% identity (100.0% similar) in 1052 aa overlap (1-1052:23-1074)
10 20 30
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLK
::::::::::::::::::::::::::::::::::::::
NP_005 MISADCNLCLPEYDRYLASSKIMAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE1 VFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 HVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 IADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 TLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 GISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 NMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE1 EIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE1 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE1 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYK
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE1 ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENG
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE1 ERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE1 ATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAG
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE1 SIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQE
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE1 MEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPR
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE1 PGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEM
910 920 930 940 950 960
940 950 960 970 980 990
pF1KE1 SSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELI
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KE1 NKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050 1060 1070
>>XP_024302973 (OMIM: 600758) focal adhesion kinase 1 is (1103 aa)
initn: 7054 init1: 7054 opt: 7054 Z-score: 2853.4 bits: 539.7 E(92320): 3.6e-152
Smith-Waterman score: 7054; 100.0% identity (100.0% similar) in 1052 aa overlap (1-1052:52-1103)
10 20 30
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSP
::::::::::::::::::::::::::::::
XP_024 QLQIQCLLQFPQSSSRITEEYDRYLASSKIMAAAYLDPNLNHTPNSSTKTHLGTGMERSP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE1 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE1 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE1 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE1 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
630 640 650 660 670 680
640 650 660 670 680 690
pF1KE1 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
690 700 710 720 730 740
700 710 720 730 740 750
pF1KE1 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
750 760 770 780 790 800
760 770 780 790 800 810
pF1KE1 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
810 820 830 840 850 860
820 830 840 850 860 870
pF1KE1 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
870 880 890 900 910 920
880 890 900 910 920 930
pF1KE1 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTG
930 940 950 960 970 980
940 950 960 970 980 990
pF1KE1 LVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLL
990 1000 1010 1020 1030 1040
1000 1010 1020 1030 1040 1050
pF1KE1 NSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 NSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTR
1050 1060 1070 1080 1090 1100
pF1KE1 PH
::
XP_024 PH
>>NP_001339649 (OMIM: 600758) focal adhesion kinase 1 is (1055 aa)
initn: 6114 init1: 6114 opt: 7038 Z-score: 2847.2 bits: 538.5 E(92320): 8.1e-152
Smith-Waterman score: 7038; 99.7% identity (99.7% similar) in 1055 aa overlap (1-1052:1-1055)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
850 860 870 880 890 900
910 920 930 940 950
pF1KE1 GVK---LQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE1 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
970 980 990 1000 1010 1020
1020 1030 1040 1050
pF1KE1 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
:::::::::::::::::::::::::::::::::::
NP_001 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
>>NP_001339648 (OMIM: 600758) focal adhesion kinase 1 is (1055 aa)
initn: 6114 init1: 6114 opt: 7038 Z-score: 2847.2 bits: 538.5 E(92320): 8.1e-152
Smith-Waterman score: 7038; 99.7% identity (99.7% similar) in 1055 aa overlap (1-1052:1-1055)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
850 860 870 880 890 900
910 920 930 940 950
pF1KE1 GVK---LQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE1 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
970 980 990 1000 1010 1020
1020 1030 1040 1050
pF1KE1 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
:::::::::::::::::::::::::::::::::::
NP_001 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
>>NP_001339647 (OMIM: 600758) focal adhesion kinase 1 is (1055 aa)
initn: 6114 init1: 6114 opt: 7038 Z-score: 2847.2 bits: 538.5 E(92320): 8.1e-152
Smith-Waterman score: 7038; 99.7% identity (99.7% similar) in 1055 aa overlap (1-1052:1-1055)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE1 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE1 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE1 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE1 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE1 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE1 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
850 860 870 880 890 900
910 920 930 940 950
pF1KE1 GVK---LQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEV
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE1 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYK
970 980 990 1000 1010 1020
1020 1030 1040 1050
pF1KE1 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
:::::::::::::::::::::::::::::::::::
NP_001 KQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
>>XP_016869146 (OMIM: 600758) focal adhesion kinase 1 is (1099 aa)
initn: 6114 init1: 6114 opt: 7038 Z-score: 2847.1 bits: 538.5 E(92320): 8.3e-152
Smith-Waterman score: 7038; 99.7% identity (99.7% similar) in 1055 aa overlap (1-1052:45-1099)
10 20 30
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSP
::::::::::::::::::::::::::::::
XP_016 GAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNSSTKTHLGTGMERSP
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE1 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE1 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE1 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
320 330 340 350 360 370
340 350 360 370 380 390
pF1KE1 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
380 390 400 410 420 430
400 410 420 430 440 450
pF1KE1 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
440 450 460 470 480 490
460 470 480 490 500 510
pF1KE1 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
500 510 520 530 540 550
520 530 540 550 560 570
pF1KE1 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
560 570 580 590 600 610
580 590 600 610 620 630
pF1KE1 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
620 630 640 650 660 670
640 650 660 670 680 690
pF1KE1 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
680 690 700 710 720 730
700 710 720 730 740 750
pF1KE1 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
740 750 760 770 780 790
760 770 780 790 800 810
pF1KE1 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
800 810 820 830 840 850
820 830 840 850 860 870
pF1KE1 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
860 870 880 890 900 910
880 890 900 910 920
pF1KE1 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVK---LQPQEISPPPTANLDRSNDKVYEN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_016 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYEN
920 930 940 950 960 970
930 940 950 960 970 980
pF1KE1 VTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQ
980 990 1000 1010 1020 1030
990 1000 1010 1020 1030 1040
pF1KE1 KLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLG
1040 1050 1060 1070 1080 1090
1050
pF1KE1 QTRPH
:::::
XP_016 QTRPH
>>XP_024302972 (OMIM: 600758) focal adhesion kinase 1 is (1106 aa)
initn: 6114 init1: 6114 opt: 7038 Z-score: 2847.0 bits: 538.5 E(92320): 8.3e-152
Smith-Waterman score: 7038; 99.7% identity (99.7% similar) in 1055 aa overlap (1-1052:52-1106)
10 20 30
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSP
::::::::::::::::::::::::::::::
XP_024 QLQIQCLLQFPQSSSRITEEYDRYLASSKIMAAAYLDPNLNHTPNSSTKTHLGTGMERSP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQ
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKS
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISV
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 ELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVT
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 APSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVS
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE1 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALA
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE1 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSF
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE1 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 LQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRY
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE1 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNND
630 640 650 660 670 680
640 650 660 670 680 690
pF1KE1 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEER
690 700 710 720 730 740
700 710 720 730 740 750
pF1KE1 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 MRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGS
750 760 770 780 790 800
760 770 780 790 800 810
pF1KE1 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 HGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEE
810 820 830 840 850 860
820 830 840 850 860 870
pF1KE1 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPA
870 880 890 900 910 920
880 890 900 910 920
pF1KE1 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVK---LQPQEISPPPTANLDRSNDKVYEN
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
XP_024 APPKKPPRPGAPGHLGSLASLSSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYEN
930 940 950 960 970 980
930 940 950 960 970 980
pF1KE1 VTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 VTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQ
990 1000 1010 1020 1030 1040
990 1000 1010 1020 1030 1040
pF1KE1 KLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 KLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLG
1050 1060 1070 1080 1090 1100
1050
pF1KE1 QTRPH
:::::
XP_024 QTRPH
>>NP_001339646 (OMIM: 600758) focal adhesion kinase 1 is (1058 aa)
initn: 4456 init1: 4456 opt: 7032 Z-score: 2844.8 bits: 538.0 E(92320): 1.1e-151
Smith-Waterman score: 7032; 99.4% identity (99.4% similar) in 1058 aa overlap (1-1052:1-1058)
10 20 30 40 50 60
pF1KE1 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
310 320 330 340 350 360
370 380 390 400 410
pF1KE1 RPQKEGERALPSIPKLANSEKQGMRTHAVSVS------ETDDYAEIIDEEDTYTMPSTRD
:::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 RPQKEGERALPSIPKLANSEKQGMRTHAVSVSDEISGDETDDYAEIIDEEDTYTMPSTRD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE1 YEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALT
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE1 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE1 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE1 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE1 MTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPK
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE1 PSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSW
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE1 NHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLK
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE1 PDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE1 ADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMV
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE1 KEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQ
970 980 990 1000 1010 1020
1020 1030 1040 1050
pF1KE1 EYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
::::::::::::::::::::::::::::::::::::::
NP_001 EYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
1030 1040 1050
1052 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:55:57 2019 done: Thu Oct 24 21:55:58 2019
Total Scan time: 7.770 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]