FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1617, 127 aa 1>>>pF1KE1617 127 - 127 aa - 127 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4996+/-0.000346; mu= 10.0470+/- 0.022 mean_var=66.7353+/-13.245, 0's: 0 Z-trim(113.9): 32 B-trim: 0 in 0/53 Lambda= 0.156999 statistics sampled from 24334 (24362) to 24334 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.264), width: 16 Scan time: 2.820 The best scores are: opt bits E(92320) NP_733759 (OMIM: 609904) histone H2B type 1-A [Hom ( 127) 771 183.1 1.2e-46 NP_003510 (OMIM: 602800) histone H2B type 1-L [Hom ( 126) 673 160.9 5.6e-40 NP_003511 (OMIM: 602801) histone H2B type 1-N [Hom ( 126) 670 160.2 8.9e-40 NP_066406 (OMIM: 602803) histone H2B type 1-B [Hom ( 126) 670 160.2 8.9e-40 NP_619790 (OMIM: 602799) histone H2B type 1-D [Hom ( 126) 667 159.5 1.4e-39 NP_066407 (OMIM: 602799) histone H2B type 1-D [Hom ( 126) 667 159.5 1.4e-39 NP_003519 (OMIM: 601831) histone H2B type 2-E [Hom ( 126) 667 159.5 1.4e-39 NP_778225 (OMIM: 615046) histone H2B type 3-B [Hom ( 126) 667 159.5 1.4e-39 XP_005249096 (OMIM: 602799) histone H2B type 1-D i ( 150) 667 159.5 1.7e-39 NP_003513 (OMIM: 602804) histone H2B type 1-C/E/F/ ( 126) 666 159.3 1.7e-39 NP_003517 (OMIM: 602847) histone H2B type 1-C/E/F/ ( 126) 666 159.3 1.7e-39 NP_003509 (OMIM: 602798) histone H2B type 1-C/E/F/ ( 126) 666 159.3 1.7e-39 NP_003516 (OMIM: 602807) histone H2B type 1-C/E/F/ ( 126) 666 159.3 1.7e-39 NP_003514 (OMIM: 602805) histone H2B type 1-C/E/F/ ( 126) 666 159.3 1.7e-39 NP_003512 (OMIM: 602802) histone H2B type 1-M [Hom ( 126) 664 158.8 2.3e-39 NP_066402 (OMIM: 615044) histone H2B type 1-J [Hom ( 126) 663 158.6 2.7e-39 NP_003518 (OMIM: 602808) histone H2B type 1-O [Hom ( 126) 663 158.6 2.7e-39 NP_001299582 (OMIM: 615045) histone H2B type 1-K [ ( 126) 662 158.4 3.1e-39 NP_003515 (OMIM: 602806) histone H2B type 1-H [Hom ( 126) 662 158.4 3.1e-39 NP_542160 (OMIM: 615045) histone H2B type 1-K [Hom ( 126) 662 158.4 3.1e-39 NP_001002916 (OMIM: 300507) histone H2B type W-T [ ( 175) 299 76.2 2.3e-14 >>NP_733759 (OMIM: 609904) histone H2B type 1-A [Homo sa (127 aa) initn: 771 init1: 771 opt: 771 Z-score: 959.3 bits: 183.1 E(92320): 1.2e-46 Smith-Waterman score: 771; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_733 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_733 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV 70 80 90 100 110 120 pF1KE1 TKYTSSK ::::::: NP_733 TKYTSSK >>NP_003510 (OMIM: 602800) histone H2B type 1-L [Homo sa (126 aa) initn: 661 init1: 661 opt: 673 Z-score: 839.4 bits: 160.9 E(92320): 5.6e-40 Smith-Waterman score: 673; 85.8% identity (96.1% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA :::.. :.: ::: ::::.:.:::.::::::.::::::.:.::::::::::::::::: NP_003 MPELA-KSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.::::::::::::::::.:::::.:::::::::::::::::::::::::::: NP_003 MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_003 TKYTSSK 120 >>NP_003511 (OMIM: 602801) histone H2B type 1-N [Homo sa (126 aa) initn: 660 init1: 660 opt: 670 Z-score: 835.7 bits: 160.2 E(92320): 8.9e-40 Smith-Waterman score: 670; 85.8% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: ::.: ::: ::::.:.:::.::::::.::::::.:.::::::::::::::::: NP_003 MPE-PSKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_003 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_003 TKYTSSK 120 >>NP_066406 (OMIM: 602803) histone H2B type 1-B [Homo sa (126 aa) initn: 660 init1: 660 opt: 670 Z-score: 835.7 bits: 160.2 E(92320): 8.9e-40 Smith-Waterman score: 670; 85.8% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: ::.: ::: :::..:.:::.::::::.::::::::.::::::::::::::::: NP_066 MPE-PSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_066 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_066 TKYTSSK 120 >>NP_619790 (OMIM: 602799) histone H2B type 1-D [Homo sa (126 aa) initn: 657 init1: 657 opt: 667 Z-score: 832.0 bits: 159.5 E(92320): 1.4e-39 Smith-Waterman score: 667; 85.0% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: .:.: ::: ::::.:.:::.::::::.::::::.:.::::::::::::::::: NP_619 MPE-PTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_619 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_619 TKYTSSK 120 >>NP_066407 (OMIM: 602799) histone H2B type 1-D [Homo sa (126 aa) initn: 657 init1: 657 opt: 667 Z-score: 832.0 bits: 159.5 E(92320): 1.4e-39 Smith-Waterman score: 667; 85.0% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: .:.: ::: ::::.:.:::.::::::.::::::.:.::::::::::::::::: NP_066 MPE-PTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_066 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_066 TKYTSSK 120 >>NP_003519 (OMIM: 601831) histone H2B type 2-E [Homo sa (126 aa) initn: 657 init1: 657 opt: 667 Z-score: 832.0 bits: 159.5 E(92320): 1.4e-39 Smith-Waterman score: 667; 85.8% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: .:.: ::: ::::.:.:::.::::::.::::::::.::::::::::::::::: NP_003 MPE-PAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_003 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_003 TKYTSSK 120 >>NP_778225 (OMIM: 615046) histone H2B type 3-B [Homo sa (126 aa) initn: 661 init1: 661 opt: 667 Z-score: 832.0 bits: 159.5 E(92320): 1.4e-39 Smith-Waterman score: 667; 85.8% identity (94.5% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::. ::.: ::: ::::.:.:::.:::::: ::::::::.::::::::::::::::: NP_778 MPD-PSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.::::::::::::::::.:::::.:::.:::::::::::::::::::::::: NP_778 MGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_778 TKYTSSK 120 >>XP_005249096 (OMIM: 602799) histone H2B type 1-D isofo (150 aa) initn: 657 init1: 657 opt: 667 Z-score: 830.8 bits: 159.5 E(92320): 1.7e-39 Smith-Waterman score: 667; 85.0% identity (95.3% similar) in 127 aa overlap (1-127:25-150) 10 20 30 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRK ::: .:.: ::: ::::.:.:::.::::::.:: XP_005 MNRASAGVIIFSGVCNSVLTINATMPE-PTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRK 10 20 30 40 50 40 50 60 70 80 90 pF1KE1 ESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREI ::::.:.::::::::::::::::::.::::::.:::::::.::::::::.:::::.:::: XP_005 ESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREI 60 70 80 90 100 110 100 110 120 pF1KE1 QTAVRLLLPGELAKHAVSEGTKAVTKYTSSK ::::::::::::::::::::::::::::::: XP_005 QTAVRLLLPGELAKHAVSEGTKAVTKYTSSK 120 130 140 150 >>NP_003513 (OMIM: 602804) histone H2B type 1-C/E/F/G/I (126 aa) initn: 656 init1: 656 opt: 666 Z-score: 830.8 bits: 159.3 E(92320): 1.7e-39 Smith-Waterman score: 666; 85.0% identity (95.3% similar) in 127 aa overlap (1-127:1-126) 10 20 30 40 50 60 pF1KE1 MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKA ::: .:.: ::: ::::.:.:::.::::::.::::::.:.::::::::::::::::: NP_003 MPE-PAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 MSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAV :.::::::.:::::::.::::::::.:::::.:::::::::::::::::::::::::::: NP_003 MGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAV 60 70 80 90 100 110 pF1KE1 TKYTSSK ::::::: NP_003 TKYTSSK 120 127 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:40:13 2019 done: Thu Oct 24 21:40:13 2019 Total Scan time: 2.820 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]