FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1689, 199 aa 1>>>pF1KE1689 199 - 199 aa - 199 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3840+/-0.000256; mu= 6.8077+/- 0.016 mean_var=151.3059+/-30.863, 0's: 0 Z-trim(125.8): 2 B-trim: 1629 in 1/60 Lambda= 0.104267 statistics sampled from 50372 (50374) to 50372 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.853), E-opt: 0.2 (0.591), width: 16 Scan time: 7.940 The best scores are: opt bits E(85289) NP_000632 (OMIM: 147681) interleukin-11 isoform 1 ( 199) 1338 211.2 8.7e-55 NP_001254647 (OMIM: 147681) interleukin-11 isoform ( 120) 797 129.7 1.9e-30 >>NP_000632 (OMIM: 147681) interleukin-11 isoform 1 prec (199 aa) initn: 1338 init1: 1338 opt: 1338 Z-score: 1104.5 bits: 211.2 E(85289): 8.7e-55 Smith-Waterman score: 1338; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199) 10 20 30 40 50 60 pF1KE1 MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 RDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 TLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGG 130 140 150 160 170 180 190 pF1KE1 LHLTLDWAVRGLLLLKTRL ::::::::::::::::::: NP_000 LHLTLDWAVRGLLLLKTRL 190 >>NP_001254647 (OMIM: 147681) interleukin-11 isoform 2 [ (120 aa) initn: 797 init1: 797 opt: 797 Z-score: 667.8 bits: 129.7 E(85289): 1.9e-30 Smith-Waterman score: 797; 100.0% identity (100.0% similar) in 120 aa overlap (80-199:1-120) 50 60 70 80 90 100 pF1KE1 LADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQ :::::::::::::::::::::::::::::: NP_001 MSAGALGALQLPGVLTRLRADLLSYLRHVQ 10 20 30 110 120 130 140 150 160 pF1KE1 WLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWG 40 50 60 70 80 90 170 180 190 pF1KE1 GIRAAHAILGGLHLTLDWAVRGLLLLKTRL :::::::::::::::::::::::::::::: NP_001 GIRAAHAILGGLHLTLDWAVRGLLLLKTRL 100 110 120 199 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 04:49:04 2016 done: Mon Nov 7 04:49:05 2016 Total Scan time: 7.940 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]