FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1731, 239 aa
1>>>pF1KE1731 239 - 239 aa - 239 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4183+/-0.000609; mu= 15.2397+/- 0.037
mean_var=79.3508+/-15.666, 0's: 0 Z-trim(113.3): 35 B-trim: 0 in 0/52
Lambda= 0.143979
statistics sampled from 14079 (14114) to 14079 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.422), width: 16
Scan time: 1.200
The best scores are: opt bits E(33420)
CCDS8195.1 FGF3 gene_id:2248|Hs109|chr11 ( 239) 1617 344.4 4e-95
CCDS34021.1 FGF5 gene_id:2250|Hs109|chr4 ( 268) 349 81.1 8.4e-16
CCDS12037.1 FGF22 gene_id:27006|Hs109|chr19 ( 170) 339 78.9 2.5e-15
CCDS3950.1 FGF10 gene_id:2255|Hs109|chr5 ( 208) 338 78.7 3.4e-15
CCDS9298.1 FGF9 gene_id:2254|Hs109|chr13 ( 208) 332 77.5 8e-15
CCDS5998.1 FGF20 gene_id:26281|Hs109|chr8 ( 211) 330 77.1 1.1e-14
CCDS75996.1 FGF16 gene_id:8823|Hs109|chrX ( 207) 324 75.8 2.5e-14
CCDS8527.1 FGF6 gene_id:2251|Hs109|chr12 ( 208) 299 70.6 9.2e-13
CCDS10131.1 FGF7 gene_id:2252|Hs109|chr15 ( 194) 282 67.1 1e-11
>>CCDS8195.1 FGF3 gene_id:2248|Hs109|chr11 (239 aa)
initn: 1617 init1: 1617 opt: 1617 Z-score: 1821.5 bits: 344.4 E(33420): 4e-95
Smith-Waterman score: 1617; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)
10 20 30 40 50 60
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 SGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 IHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLP
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 RVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 RVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
190 200 210 220 230
>>CCDS34021.1 FGF5 gene_id:2250|Hs109|chr4 (268 aa)
initn: 368 init1: 312 opt: 349 Z-score: 397.4 bits: 81.1 E(33420): 8.4e-16
Smith-Waterman score: 404; 37.1% identity (67.0% similar) in 197 aa overlap (17-209:63-246)
10 20 30 40
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRR
:::. :.. .: . . .. .. :
CCDS34 GPAATDRNPRGSSSRQSSSSAMSSSSASSSPAASLGSQ---GSGLEQSSFQWSPSGRRTG
40 50 60 70 80
50 60 70 80 90 100
pF1KE1 KLYC--ATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGR
.::: . .:::..:.:.:::: : . :.::: :: :::.:::.::...:::.:.:.
CCDS34 SLYCRVGIGFHLQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGK
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE1 LYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPR
:.:: ... .:.: ::..: .:::::: ..:: .. : : :::..: .:. .
CCDS34 LHASAKFTDDCKFRERFQENSYNTYASAIHRTEKT--G--------REWYVALNKRGKAK
150 160 170 180 190
170 180 190 200 210 220
pF1KE1 RGFKTR-RTQK-SSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEP
:: . : . :. :. :::: . .. :. . . : . ..:.
CCDS34 RGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKKPPSPIKPKIPLSAPRKNTNSV
200 210 220 230 240 250
230
pF1KE1 SHVQASRLGSQLEASAH
CCDS34 KYRLKFRFG
260
>>CCDS12037.1 FGF22 gene_id:27006|Hs109|chr19 (170 aa)
initn: 352 init1: 234 opt: 339 Z-score: 388.9 bits: 78.9 E(33420): 2.5e-15
Smith-Waterman score: 392; 41.2% identity (65.9% similar) in 182 aa overlap (1-180:7-166)
10 20 30 40 50
pF1KE1 MGLIWLLLLSLLEP-GWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATK
.:: :::: . : :.:. : : : :: : : :.:. .:.
CCDS12 MRRRLWLGLAWLLLARAPDAAGTPSASRGPR----------SYPHLEGDVRWRRLFSSTH
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 YHLQLHPSGRVNGS-LENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYS
. :.. :.:::.:. ... ::::: .:.::.:.:... :: :.:::.:::::.:. :.
CCDS12 FFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 AECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRT
..:.: :::.: :.:::::. .: : :: ..... .: :: : .:::
CCDS12 VDCRFRERIEENGHNTYASQRWRR-------RGQP-----MFLALDRRGGPRPGGRTRRY
120 130 140 150
180 190 200 210 220 230
pF1KE1 QKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGS
. :. :::
CCDS12 HLSAHFLPVLVS
160 170
>>CCDS3950.1 FGF10 gene_id:2255|Hs109|chr5 (208 aa)
initn: 448 init1: 252 opt: 338 Z-score: 386.6 bits: 78.7 E(33420): 3.4e-15
Smith-Waterman score: 422; 47.4% identity (71.2% similar) in 156 aa overlap (29-183:63-206)
10 20 30 40 50
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQL
:: . :.:: : : :::. ::: :..
CCDS39 VPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKI
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE1 HPSGRVNGSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEF
. .:.:.:. :: :::::::.::.:.::.... :. ::::::.:.::.:.... .:..
CCDS39 EKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKL
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE1 VERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSL
:::.: ::::::: .. . : ::..:::: :::: :::: . :.
CCDS39 KERIEENGYNTYASFNWQHNG------------RQMYVALNGKGAPRRGQKTRRKNTSAH
160 170 180 190 200
180 190 200 210 220 230
pF1KE1 FLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEAS
::: :.
CCDS39 FLPMVVHS
>>CCDS9298.1 FGF9 gene_id:2254|Hs109|chr13 (208 aa)
initn: 429 init1: 210 opt: 332 Z-score: 379.8 bits: 77.5 E(33420): 8e-15
Smith-Waterman score: 418; 44.2% identity (71.2% similar) in 163 aa overlap (28-184:41-193)
10 20 30 40 50
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGG--RGGVY---EHLGGAPRRRKLYCAT
.::: :: . .:: : :::.::: :
CCDS92 FGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRT
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 KYHLQLHPSGRVNGSLEN-SAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHY
.::.. :.: ..:. .. : ..:::. .. ::.:.:::. :: ::.::..:.::.::.
CCDS92 GFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKL
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 SAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRR
. :: : :...: ::::.: ::. :.. .:: .::..: : ::.: .:.:
CCDS92 TQECVFREQFEENWYNTYSSNLYKHVDT---GRR-------YYVALNKDGTPREGTRTKR
140 150 160 170 180
180 190 200 210 220 230
pF1KE1 TQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLG
:: . :::: .:
CCDS92 HQKFTHFLPRPVDPDKVPELYKDILSQS
190 200
>>CCDS5998.1 FGF20 gene_id:26281|Hs109|chr8 (211 aa)
initn: 393 init1: 202 opt: 330 Z-score: 377.5 bits: 77.1 E(33420): 1.1e-14
Smith-Waterman score: 407; 41.9% identity (68.6% similar) in 172 aa overlap (26-194:46-207)
10 20 30 40 50
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVY-EHLGGAPRRRKLYCATKY
: :: :.. :: : :::.::: : .
CCDS59 GLGQQVGSHFLLPPAGERPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTGF
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE1 HLQLHPSGRVNGSLEN-SAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSA
:::. :.: :.:. .. : ..:::. .: ::.:.:::. :: ::.:: .:.::.::. ..
CCDS59 HLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTS
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE1 ECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQ
:: : :...: ::::.: .:. . .. : ..:..: : :: : ...: :
CCDS59 ECIFREQFEENWYNTYSSNIYK----------HGDTGRRYFVALNKDGTPRDGARSKRHQ
140 150 160 170 180
180 190 200 210 220 230
pF1KE1 KSSLFLPRVLD-HRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGS
: . :::: .: .: :. ..:
CCDS59 KFTHFLPRPVDPERVPELYKDLLMYT
190 200 210
>>CCDS75996.1 FGF16 gene_id:8823|Hs109|chrX (207 aa)
initn: 430 init1: 204 opt: 324 Z-score: 370.9 bits: 75.8 E(33420): 2.5e-14
Smith-Waterman score: 423; 44.7% identity (72.7% similar) in 150 aa overlap (36-184:53-192)
10 20 30 40 50 60
pF1KE1 LLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVN
. :: : :::.::: : .::.. :.: :.
CCDS75 GNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTGFHLEIFPNGTVH
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 GSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHEL
:. ..: ..:::. .. ::...:::. :: ::.::.::.::.:.. . :: : :...:
CCDS75 GTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEEN
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 GYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLD
:::::: ::. . ..:: .::..: : ::.:..:.: :: . :::: .:
CCDS75 WYNTYASTLYK----------HSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVD
150 160 170 180 190
190 200 210 220 230
pF1KE1 HRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
CCDS75 PSKLPSMSRDLFHYR
200
>>CCDS8527.1 FGF6 gene_id:2251|Hs109|chr12 (208 aa)
initn: 343 init1: 260 opt: 299 Z-score: 342.8 bits: 70.6 E(33420): 9.2e-13
Smith-Waterman score: 324; 35.0% identity (60.6% similar) in 180 aa overlap (5-182:54-208)
10 20 30
pF1KE1 MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGG
: ::: . : :: : . ..:
CCDS85 ALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSRSRAG--LAGEIAGVNWESG----
30 40 50 60 70
40 50 60 70 80 90
pF1KE1 VYEHLGGAPRRRKLYCATK--YHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLF
.: : :.:.::: . .:::. :.::..:. :.. ::.:::..:: :.:.. :.
CCDS85 ---YLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 SGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERL
:. ..:::..:::::. .. ::.: : . .::.: : ::. .
CCDS85 SALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGT---------------
140 150 160 170
160 170 180 190 200 210
pF1KE1 WYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRR
:.... :: .:: :. . . ::::.
CCDS85 -YIALSKYGRVKRGSKVSPIMTVTHFLPRI
180 190 200
>>CCDS10131.1 FGF7 gene_id:2252|Hs109|chr15 (194 aa)
initn: 282 init1: 200 opt: 282 Z-score: 324.1 bits: 67.1 E(33420): 1e-11
Smith-Waterman score: 337; 42.2% identity (69.4% similar) in 147 aa overlap (36-180:56-190)
10 20 30 40 50 60
pF1KE1 LLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHL-GGAPRRRKLYCATKYHLQLHPSGRV
:... :: : :.:.: :...:.. :.:
CCDS10 GTISLACNDMTPEQMATNVNCSSPERHTRSYDYMEGGDIRVRRLFCRTQWYLRIDKRGKV
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE1 NGSLE-NSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHE
.:. : .. :.:.:: .: ::::::.:. : ::::::.:.:::... . .:.: : : :
CCDS10 KGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEGKLYAKKECNEDCNFKELILE
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE1 LGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVL
:::::: :. .. .. .:..: :: : :: ::.. ::.. :::
CCDS10 NHYNTYAS-----------AKWTHNGGEM-FVALNQKGIPVRGKKTKKEQKTAHFLPMAI
150 160 170 180 190
190 200 210 220 230
pF1KE1 DHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
CCDS10 T
239 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:47:33 2019 done: Tue Jul 16 15:47:33 2019
Total Scan time: 1.200 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]