FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1747, 251 aa
  1>>>pF1KE1747 251 - 251 aa - 251 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1463+/-0.000691; mu= 11.5475+/- 0.042
 mean_var=92.0056+/-18.274, 0's: 0 Z-trim(112.4): 36  B-trim: 15 in 1/49
 Lambda= 0.133711
 statistics sampled from 13170 (13206) to 13170 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.406), width:  16
 Scan time:  1.870

The best scores are:                                      opt bits E(32554)
CCDS8526.1 FGF23 gene_id:8074|Hs108|chr12          ( 251) 1760 348.8   2e-96
CCDS12734.1 FGF21 gene_id:26291|Hs108|chr19        ( 209)  312 69.4 2.1e-12


>>CCDS8526.1 FGF23 gene_id:8074|Hs108|chr12               (251 aa)
 initn: 1760 init1: 1760 opt: 1760  Z-score: 1844.5  bits: 348.8 E(32554): 2e-96
Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)

               10        20        30        40        50        60
pF1KE1 MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MLGARLRLWVCALCSVCSMSVLRAYPNASPLLGSSWGGLIHLYTATARNSYHLQIHKNGH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 VDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 VDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFDPENCRFQHQTL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 ENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 ENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHFNTPIPRRHTRS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE1 AEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 AEDDSERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVRGGRVNTHAGGTG
              190       200       210       220       230       240

              250 
pF1KE1 PEGCRPFAKFI
       :::::::::::
CCDS85 PEGCRPFAKFI
              250 

>>CCDS12734.1 FGF21 gene_id:26291|Hs108|chr19             (209 aa)
 initn: 279 init1: 228 opt: 312  Z-score: 336.0  bits: 69.4 E(32554): 2.1e-12
Smith-Waterman score: 312; 32.2% identity (57.6% similar) in 205 aa overlap (8-205:13-209)

                    10        20          30        40           50
pF1KE1      MLGARLRLWVCALCSVCSMSVLRAYP--NASPLLGSSWGGLI---HLYTATARNS
                   ::: .: ..  ... .:.:  ..::::  ..:: .   .:::  :...
CCDS12 MDSDETGFEHSGLWVSVLAGLL-LGACQAHPIPDSSPLL--QFGGQVRQRYLYTDDAQQT
               10        20         30          40        50       

                60        70        80        90       100         
pF1KE1 Y-HLQIHKNGHVDGAPHQTIYSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGSHYFD
         ::.:...: : ::  :.  : :....   : . : :: . :.::.   : ..:: .::
CCDS12 EAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFD
        60        70        80        90       100       110       

     110       120       130       140       150       160         
pF1KE1 PENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMNPPPYSQFLSRRNEIPLIHF
       :: : :..  ::.::.::.:  . . . :   :    :  .: : .   .:   .: .  
CCDS12 PEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKS---PHRDPAPRGP--ARFLPLPGLPP
       120       130       140       150          160         170  

     170       180        190       200       210       220        
pF1KE1 NTPIPRRHTRSAEDD-SERDPLNVLKPRARMTPAPASCSQELPSAEDNSPMASDPLGVVR
         : :         : .  :::... :    .:. ::                       
CCDS12 ALPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS                       
            180       190       200                                

      230       240       250 
pF1KE1 GGRVNTHAGGTGPEGCRPFAKFI




251 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 14:57:57 2016 done: Sun Nov  6 14:57:57 2016
 Total Scan time:  1.870 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]