FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1772, 279 aa 1>>>pF1KE1772 279 - 279 aa - 279 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1581+/-0.000274; mu= -0.0788+/- 0.017 mean_var=247.5482+/-50.397, 0's: 0 Z-trim(126.5): 5 B-trim: 973 in 1/58 Lambda= 0.081516 statistics sampled from 54755 (54770) to 54755 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.856), E-opt: 0.2 (0.593), width: 16 Scan time: 4.480 The best scores are: opt bits E(92320) NP_005470 (OMIM: 602503) proto-oncogene FRAT1 [Hom ( 279) 1913 236.8 3.9e-62 NP_036215 (OMIM: 605006) GSK-3-binding protein FRA ( 233) 872 114.3 2.4e-25 >>NP_005470 (OMIM: 602503) proto-oncogene FRAT1 [Homo sa (279 aa) initn: 1913 init1: 1913 opt: 1913 Z-score: 1237.2 bits: 236.8 E(92320): 3.9e-62 Smith-Waterman score: 1913; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279) 10 20 30 40 50 60 pF1KE1 MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL 190 200 210 220 230 240 250 260 270 pF1KE1 SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS ::::::::::::::::::::::::::::::::::::::: NP_005 SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS 250 260 270 >>NP_036215 (OMIM: 605006) GSK-3-binding protein FRAT2 [ (233 aa) initn: 1169 init1: 868 opt: 872 Z-score: 576.6 bits: 114.3 E(92320): 2.4e-25 Smith-Waterman score: 1136; 71.2% identity (78.0% similar) in 264 aa overlap (1-263:1-231) 10 20 30 40 50 60 pF1KE1 MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP :::::::::::::::::::::.::::::::::.:::::::::::::::::::::::: :: NP_036 MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR ::::.:::.:::::::::::::::::: :::::::::: :::::::: :.:::::::::: NP_036 ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR ::::::::::::.:.::::: :: :::::::: :..:: NP_036 VRGRAAPYCVAEVAAGPSAL------------PG------------PCRRGWLRDAVTSR 130 140 150 190 200 210 220 230 240 pF1KE1 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL :::::: .: .:.::::::::::::::::::::::::::. . : :: NP_036 RLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAAT-------GPA 160 170 180 190 200 250 260 270 pF1KE1 SAPVHEPPSPRS-PRAACSDPGASGRAQLRTGDGVLVPGS ::: : . :: : .:..: NP_036 SAP--GPGGGRSGPDRIALQPSGSLL 210 220 230 279 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:44:33 2019 done: Thu Oct 24 21:44:34 2019 Total Scan time: 4.480 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]