FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1798, 802 aa 1>>>pF1KE1798 802 - 802 aa - 802 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2221+/-0.00054; mu= -8.9045+/- 0.032 mean_var=596.7601+/-140.710, 0's: 0 Z-trim(116.5): 1844 B-trim: 874 in 1/54 Lambda= 0.052502 statistics sampled from 26384 (28831) to 26384 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.312), width: 16 Scan time: 6.220 The best scores are: opt bits E(92320) NP_004746 (OMIM: 603607) ribosomal protein S6 kina ( 802) 5298 418.1 8.2e-116 NP_001309158 (OMIM: 603607) ribosomal protein S6 k ( 795) 5229 412.9 3.1e-114 NP_001309164 (OMIM: 603607) ribosomal protein S6 k ( 723) 4793 379.8 2.5e-104 NP_001309166 (OMIM: 603607) ribosomal protein S6 k ( 723) 4793 379.8 2.5e-104 NP_001309161 (OMIM: 603607) ribosomal protein S6 k ( 729) 4473 355.5 5e-97 NP_001309163 (OMIM: 603607) ribosomal protein S6 k ( 610) 3992 319.0 4.2e-86 NP_001309157 (OMIM: 603607) ribosomal protein S6 k ( 766) 3992 319.1 4.8e-86 XP_016877275 (OMIM: 603607) ribosomal protein S6 k ( 583) 3902 312.2 4.6e-84 NP_001309167 (OMIM: 603607) ribosomal protein S6 k ( 583) 3902 312.2 4.6e-84 NP_001309165 (OMIM: 603607) ribosomal protein S6 k ( 774) 3803 304.8 9.9e-82 NP_872198 (OMIM: 603607) ribosomal protein S6 kina ( 549) 3606 289.7 2.5e-77 NP_001309160 (OMIM: 603607) ribosomal protein S6 k ( 563) 3577 287.5 1.2e-76 NP_001309159 (OMIM: 603607) ribosomal protein S6 k ( 535) 3568 286.8 1.8e-76 NP_001309156 (OMIM: 603607) ribosomal protein S6 k ( 521) 3476 279.8 2.2e-74 NP_003933 (OMIM: 603606) ribosomal protein S6 kina ( 772) 3369 272.0 7.8e-72 NP_001006945 (OMIM: 603606) ribosomal protein S6 k ( 766) 3310 267.5 1.7e-70 NP_001287731 (OMIM: 603606) ribosomal protein S6 k ( 765) 3302 266.9 2.6e-70 NP_001305290 (OMIM: 603606) ribosomal protein S6 k ( 709) 3106 252.0 7.3e-66 NP_001309162 (OMIM: 603607) ribosomal protein S6 k ( 748) 2873 234.4 1.6e-60 XP_016874016 (OMIM: 603606) ribosomal protein S6 k ( 398) 1602 137.7 1e-31 XP_005274437 (OMIM: 603606) ribosomal protein S6 k ( 717) 1475 128.5 1.1e-28 NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1193 106.9 2.5e-22 NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1193 106.9 2.6e-22 NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1189 106.5 2.9e-22 NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1177 105.6 5.6e-22 NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1170 105.1 8.1e-22 NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 1145 103.5 3.9e-21 NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 1141 103.2 4.9e-21 NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 1133 102.6 7.3e-21 NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 1124 101.9 1.2e-20 NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 1124 101.9 1.2e-20 XP_006715612 (OMIM: 601685) ribosomal protein S6 k ( 761) 1124 101.9 1.2e-20 NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 1115 101.2 1.8e-20 XP_005274634 (OMIM: 300075,300844,303600) ribosoma ( 710) 1105 100.4 3.1e-20 XP_016885207 (OMIM: 300075,300844,303600) ribosoma ( 711) 1105 100.4 3.1e-20 XP_006724570 (OMIM: 300075,300844,303600) ribosoma ( 711) 1105 100.4 3.1e-20 XP_016885208 (OMIM: 300075,300844,303600) ribosoma ( 711) 1105 100.4 3.1e-20 XP_011543865 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_016885202 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_016885205 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_016885203 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_016885206 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_016885204 (OMIM: 300075,300844,303600) ribosoma ( 712) 1105 100.4 3.1e-20 XP_005274630 (OMIM: 300075,300844,303600) ribosoma ( 739) 1105 100.4 3.2e-20 NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 1105 100.4 3.2e-20 XP_011543864 (OMIM: 300075,300844,303600) ribosoma ( 717) 1083 98.8 9.9e-20 XP_011543863 (OMIM: 300075,300844,303600) ribosoma ( 718) 1083 98.8 9.9e-20 XP_011543859 (OMIM: 300075,300844,303600) ribosoma ( 718) 1083 98.8 9.9e-20 XP_011543862 (OMIM: 300075,300844,303600) ribosoma ( 718) 1083 98.8 9.9e-20 XP_011543860 (OMIM: 300075,300844,303600) ribosoma ( 718) 1083 98.8 9.9e-20 >>NP_004746 (OMIM: 603607) ribosomal protein S6 kinase a (802 aa) initn: 5298 init1: 5298 opt: 5298 Z-score: 2200.8 bits: 418.1 E(92320): 8.2e-116 Smith-Waterman score: 5298; 100.0% identity (100.0% similar) in 802 aa overlap (1-802:1-802) 10 20 30 40 50 60 pF1KE1 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE1 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE1 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE1 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL 730 740 750 760 770 780 790 800 pF1KE1 QPSNPADSNNPETLFQFSDSVA :::::::::::::::::::::: NP_004 QPSNPADSNNPETLFQFSDSVA 790 800 >>NP_001309158 (OMIM: 603607) ribosomal protein S6 kinas (795 aa) initn: 4189 init1: 4053 opt: 5229 Z-score: 2172.6 bits: 412.9 E(92320): 3.1e-114 Smith-Waterman score: 5229; 99.1% identity (99.1% similar) in 802 aa overlap (1-802:1-795) 10 20 30 40 50 60 pF1KE1 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE1 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE1 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA :::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_001 ESCDLWSLGVIL-------VPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 610 620 630 640 650 670 680 690 700 710 720 pF1KE1 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE1 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL 720 730 740 750 760 770 790 800 pF1KE1 QPSNPADSNNPETLFQFSDSVA :::::::::::::::::::::: NP_001 QPSNPADSNNPETLFQFSDSVA 780 790 >>NP_001309164 (OMIM: 603607) ribosomal protein S6 kinas (723 aa) initn: 4793 init1: 4793 opt: 4793 Z-score: 1994.5 bits: 379.8 E(92320): 2.5e-104 Smith-Waterman score: 4793; 100.0% identity (100.0% similar) in 723 aa overlap (80-802:1-723) 50 60 70 80 90 100 pF1KE1 ELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIR :::::::::::::::::::::::::::::: NP_001 MKVLKKATIVQKAKTTEHTRTERQVLEHIR 10 20 30 110 120 130 140 150 160 pF1KE1 QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLH 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE1 KLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE1 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE1 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KE1 EEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVA 280 290 300 310 320 330 410 420 430 440 450 460 pF1KE1 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KE1 TALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KE1 SAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYA 460 470 480 490 500 510 590 600 610 620 630 640 pF1KE1 APELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE 520 530 540 550 560 570 650 660 670 680 690 700 pF1KE1 GEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGA 580 590 600 610 620 630 710 720 730 740 750 760 pF1KE1 AVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSH 640 650 660 670 680 690 770 780 790 800 pF1KE1 SHGKTTPTKTLQPSNPADSNNPETLFQFSDSVA ::::::::::::::::::::::::::::::::: NP_001 SHGKTTPTKTLQPSNPADSNNPETLFQFSDSVA 700 710 720 >>NP_001309166 (OMIM: 603607) ribosomal protein S6 kinas (723 aa) initn: 4793 init1: 4793 opt: 4793 Z-score: 1994.5 bits: 379.8 E(92320): 2.5e-104 Smith-Waterman score: 4793; 100.0% identity (100.0% similar) in 723 aa overlap (80-802:1-723) 50 60 70 80 90 100 pF1KE1 ELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIR :::::::::::::::::::::::::::::: NP_001 MKVLKKATIVQKAKTTEHTRTERQVLEHIR 10 20 30 110 120 130 140 150 160 pF1KE1 QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLH 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE1 KLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGD 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE1 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE1 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFA 220 230 240 250 260 270 350 360 370 380 390 400 pF1KE1 EEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVA 280 290 300 310 320 330 410 420 430 440 450 460 pF1KE1 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEI 340 350 360 370 380 390 470 480 490 500 510 520 pF1KE1 TALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLV 400 410 420 430 440 450 530 540 550 560 570 580 pF1KE1 SAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYA 460 470 480 490 500 510 590 600 610 620 630 640 pF1KE1 APELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFE 520 530 540 550 560 570 650 660 670 680 690 700 pF1KE1 GEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGA 580 590 600 610 620 630 710 720 730 740 750 760 pF1KE1 AVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSH 640 650 660 670 680 690 770 780 790 800 pF1KE1 SHGKTTPTKTLQPSNPADSNNPETLFQFSDSVA ::::::::::::::::::::::::::::::::: NP_001 SHGKTTPTKTLQPSNPADSNNPETLFQFSDSVA 700 710 720 >>NP_001309161 (OMIM: 603607) ribosomal protein S6 kinas (729 aa) initn: 4473 init1: 4473 opt: 4473 Z-score: 1863.5 bits: 355.5 E(92320): 5e-97 Smith-Waterman score: 4686; 90.9% identity (90.9% similar) in 802 aa overlap (1-802:1-729) 10 20 30 40 50 60 pF1KE1 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTG-- 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA NP_001 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KE1 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----------DYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL 60 70 80 90 100 190 200 210 220 230 240 pF1KE1 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 110 120 130 140 150 160 250 260 270 280 290 300 pF1KE1 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 170 180 190 200 210 220 310 320 330 340 350 360 pF1KE1 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS 230 240 250 260 270 280 370 380 390 400 410 420 pF1KE1 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY 290 300 310 320 330 340 430 440 450 460 470 480 pF1KE1 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN 350 360 370 380 390 400 490 500 510 520 530 540 pF1KE1 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV 410 420 430 440 450 460 550 560 570 580 590 600 pF1KE1 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD 470 480 490 500 510 520 610 620 630 640 650 660 pF1KE1 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 530 540 550 560 570 580 670 680 690 700 710 720 pF1KE1 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH 590 600 610 620 630 640 730 740 750 760 770 780 pF1KE1 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL 650 660 670 680 690 700 790 800 pF1KE1 QPSNPADSNNPETLFQFSDSVA :::::::::::::::::::::: NP_001 QPSNPADSNNPETLFQFSDSVA 710 720 >>NP_001309163 (OMIM: 603607) ribosomal protein S6 kinas (610 aa) initn: 3992 init1: 3992 opt: 3992 Z-score: 1667.4 bits: 319.0 E(92320): 4.2e-86 Smith-Waterman score: 3992; 99.8% identity (100.0% similar) in 597 aa overlap (206-802:14-610) 180 190 200 210 220 230 pF1KE1 RDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKA .::::::::::::::::::::::::::::: NP_001 MNLKSNPFFVCLFKTERAYSFCGTIEYMAPDIVRGGDSGHDKA 10 20 30 40 240 250 260 270 280 290 pF1KE1 VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLM 50 60 70 80 90 100 300 310 320 330 340 350 pF1KE1 KDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEM 110 120 130 140 150 160 360 370 380 390 400 410 pF1KE1 DPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMK 170 180 190 200 210 220 420 430 440 450 460 470 pF1KE1 DSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLC 230 240 250 260 270 280 480 490 500 510 520 530 pF1KE1 EGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHM 290 300 310 320 330 340 540 550 560 570 580 590 pF1KE1 HDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLN 350 360 370 380 390 400 600 610 620 630 640 650 pF1KE1 QNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKN 410 420 430 440 450 460 660 670 680 690 700 710 pF1KE1 VSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCV 470 480 490 500 510 520 720 730 740 750 760 770 pF1KE1 KATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTT 530 540 550 560 570 580 780 790 800 pF1KE1 PTKTLQPSNPADSNNPETLFQFSDSVA ::::::::::::::::::::::::::: NP_001 PTKTLQPSNPADSNNPETLFQFSDSVA 590 600 610 >>NP_001309157 (OMIM: 603607) ribosomal protein S6 kinas (766 aa) initn: 3992 init1: 3992 opt: 3992 Z-score: 1666.4 bits: 319.1 E(92320): 4.8e-86 Smith-Waterman score: 4990; 95.5% identity (95.5% similar) in 802 aa overlap (1-802:1-766) 10 20 30 40 50 60 pF1KE1 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHK---------- 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS :::::::::::::::::::::::::::::::::: NP_001 --------------------------TERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS 180 190 200 250 260 270 280 290 300 pF1KE1 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 210 220 230 240 250 260 310 320 330 340 350 360 pF1KE1 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS 270 280 290 300 310 320 370 380 390 400 410 420 pF1KE1 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY 330 340 350 360 370 380 430 440 450 460 470 480 pF1KE1 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN 390 400 410 420 430 440 490 500 510 520 530 540 pF1KE1 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV 450 460 470 480 490 500 550 560 570 580 590 600 pF1KE1 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD 510 520 530 540 550 560 610 620 630 640 650 660 pF1KE1 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 570 580 590 600 610 620 670 680 690 700 710 720 pF1KE1 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH 630 640 650 660 670 680 730 740 750 760 770 780 pF1KE1 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL 690 700 710 720 730 740 790 800 pF1KE1 QPSNPADSNNPETLFQFSDSVA :::::::::::::::::::::: NP_001 QPSNPADSNNPETLFQFSDSVA 750 760 >>XP_016877275 (OMIM: 603607) ribosomal protein S6 kinas (583 aa) initn: 3902 init1: 3902 opt: 3902 Z-score: 1630.8 bits: 312.2 E(92320): 4.6e-84 Smith-Waterman score: 3902; 100.0% identity (100.0% similar) in 583 aa overlap (220-802:1-583) 190 200 210 220 230 240 pF1KE1 HVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELL :::::::::::::::::::::::::::::: XP_016 MAPDIVRGGDSGHDKAVDWWSLGVLMYELL 10 20 30 250 260 270 280 290 300 pF1KE1 TGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDA 40 50 60 70 80 90 310 320 330 340 350 360 pF1KE1 DEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSE 100 110 120 130 140 150 370 380 390 400 410 420 pF1KE1 KLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKD 160 170 180 190 200 210 430 440 450 460 470 480 pF1KE1 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFH 220 230 240 250 260 270 490 500 510 520 530 540 pF1KE1 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 280 290 300 310 320 330 550 560 570 580 590 600 pF1KE1 LLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLG 340 350 360 370 380 390 610 620 630 640 650 660 pF1KE1 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 400 410 420 430 440 450 670 680 690 700 710 720 pF1KE1 VDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREG 460 470 480 490 500 510 730 740 750 760 770 780 pF1KE1 FCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTLQPSNPADSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTLQPSNPADSN 520 530 540 550 560 570 790 800 pF1KE1 NPETLFQFSDSVA ::::::::::::: XP_016 NPETLFQFSDSVA 580 >>NP_001309167 (OMIM: 603607) ribosomal protein S6 kinas (583 aa) initn: 3902 init1: 3902 opt: 3902 Z-score: 1630.8 bits: 312.2 E(92320): 4.6e-84 Smith-Waterman score: 3902; 100.0% identity (100.0% similar) in 583 aa overlap (220-802:1-583) 190 200 210 220 230 240 pF1KE1 HVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELL :::::::::::::::::::::::::::::: NP_001 MAPDIVRGGDSGHDKAVDWWSLGVLMYELL 10 20 30 250 260 270 280 290 300 pF1KE1 TGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDA 40 50 60 70 80 90 310 320 330 340 350 360 pF1KE1 DEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSE 100 110 120 130 140 150 370 380 390 400 410 420 pF1KE1 KLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKD 160 170 180 190 200 210 430 440 450 460 470 480 pF1KE1 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFH 220 230 240 250 260 270 490 500 510 520 530 540 pF1KE1 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 280 290 300 310 320 330 550 560 570 580 590 600 pF1KE1 LLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLG 340 350 360 370 380 390 610 620 630 640 650 660 pF1KE1 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 400 410 420 430 440 450 670 680 690 700 710 720 pF1KE1 VDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREG 460 470 480 490 500 510 730 740 750 760 770 780 pF1KE1 FCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTLQPSNPADSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTLQPSNPADSN 520 530 540 550 560 570 790 800 pF1KE1 NPETLFQFSDSVA ::::::::::::: NP_001 NPETLFQFSDSVA 580 >>NP_001309165 (OMIM: 603607) ribosomal protein S6 kinas (774 aa) initn: 3803 init1: 3803 opt: 3803 Z-score: 1588.9 bits: 304.8 E(92320): 9.9e-82 Smith-Waterman score: 5035; 96.5% identity (96.5% similar) in 802 aa overlap (1-802:1-774) 10 20 30 40 50 60 pF1KE1 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS :::::::::::::::::::::::::: :::::: NP_001 ENILLDSNGHVVLTDFGLSKEFVADE----------------------------AVDWWS 190 200 210 250 260 270 280 290 300 pF1KE1 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE1 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE1 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE1 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE1 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV 460 470 480 490 500 510 550 560 570 580 590 600 pF1KE1 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD 520 530 540 550 560 570 610 620 630 640 650 660 pF1KE1 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA 580 590 600 610 620 630 670 680 690 700 710 720 pF1KE1 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH 640 650 660 670 680 690 730 740 750 760 770 780 pF1KE1 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL 700 710 720 730 740 750 790 800 pF1KE1 QPSNPADSNNPETLFQFSDSVA :::::::::::::::::::::: NP_001 QPSNPADSNNPETLFQFSDSVA 760 770 802 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:32:42 2019 done: Thu Oct 24 21:32:43 2019 Total Scan time: 6.220 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]