FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1808, 325 aa 1>>>pF1KE1808 325 - 325 aa - 325 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4980+/-0.000604; mu= 14.7484+/- 0.037 mean_var=109.0594+/-26.555, 0's: 0 Z-trim(105.8): 237 B-trim: 780 in 1/48 Lambda= 0.122813 statistics sampled from 13671 (13966) to 13671 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.479), E-opt: 0.2 (0.164), width: 16 Scan time: 6.050 The best scores are: opt bits E(85289) NP_002368 (OMIM: 165180) proto-oncogene Mas [Homo ( 325) 2134 390.0 3.6e-108 NP_671732 (OMIM: 607227) mas-related G-protein cou ( 322) 617 121.2 2.9e-27 NP_473371 (OMIM: 607228) mas-related G-protein cou ( 330) 609 119.8 7.9e-27 NP_001290544 (OMIM: 607228) mas-related G-protein ( 330) 609 119.8 7.9e-27 NP_473373 (OMIM: 607230) mas-related G-protein cou ( 322) 605 119.1 1.3e-26 NP_944605 (OMIM: 607231) mas-related G-protein cou ( 321) 597 117.7 3.4e-26 NP_473372 (OMIM: 607229) mas-related G-protein cou ( 322) 580 114.6 2.7e-25 XP_011518184 (OMIM: 607229) PREDICTED: mas-related ( 322) 580 114.6 2.7e-25 NP_001091985 (OMIM: 607233) mas-related G-protein ( 343) 571 113.1 8.7e-25 XP_016872659 (OMIM: 607233) PREDICTED: mas-related ( 343) 571 113.1 8.7e-25 NP_659452 (OMIM: 607233) mas-related G-protein cou ( 343) 571 113.1 8.7e-25 NP_443199 (OMIM: 607235) mas-related G-protein cou ( 378) 563 111.7 2.5e-24 NP_001034254 (OMIM: 607232) mas-related G-protein ( 312) 495 99.6 9.2e-21 NP_001157849 (OMIM: 607234) mas-related G-protein ( 289) 369 77.2 4.6e-14 NP_004769 (OMIM: 604837) prostaglandin D2 receptor ( 395) 278 61.2 4e-09 NP_001313404 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 238 54.2 6.3e-07 NP_001313406 (OMIM: 605246) C3a anaphylatoxin chem ( 482) 238 54.2 6.3e-07 NP_004045 (OMIM: 605246) C3a anaphylatoxin chemota ( 482) 238 54.2 6.3e-07 XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 233 53.2 9.7e-07 NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 233 53.2 9.7e-07 NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 233 53.2 9.8e-07 NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 233 53.2 9.8e-07 NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 233 53.2 9.8e-07 NP_001243495 (OMIM: 601919) proteinase-activated r ( 352) 229 52.5 1.5e-06 NP_004092 (OMIM: 601919) proteinase-activated rece ( 374) 229 52.5 1.6e-06 NP_001497 (OMIM: 603195) probable G-protein couple ( 356) 226 52.0 2.2e-06 NP_005282 (OMIM: 603071) uracil nucleotide/cystein ( 367) 225 51.8 2.6e-06 XP_016859322 (OMIM: 603071) PREDICTED: uracil nucl ( 367) 225 51.8 2.6e-06 NP_001154887 (OMIM: 603071) uracil nucleotide/cyst ( 367) 225 51.8 2.6e-06 NP_001154888 (OMIM: 603071) uracil nucleotide/cyst ( 339) 224 51.6 2.8e-06 NP_001154889 (OMIM: 603071) uracil nucleotide/cyst ( 339) 224 51.6 2.8e-06 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 224 51.6 2.9e-06 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 224 51.6 2.9e-06 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 224 51.6 2.9e-06 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 224 51.6 2.9e-06 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 224 51.6 2.9e-06 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 224 51.6 2.9e-06 NP_001180235 (OMIM: 136537) fMet-Leu-Phe receptor ( 350) 216 50.2 7.6e-06 NP_002020 (OMIM: 136537) fMet-Leu-Phe receptor [Ho ( 350) 216 50.2 7.6e-06 NP_005284 (OMIM: 601908) G-protein coupled recepto ( 358) 209 49.0 1.8e-05 NP_005292 (OMIM: 602646) G-protein coupled recepto ( 309) 207 48.5 2.1e-05 NP_001182311 (OMIM: 602646) G-protein coupled rece ( 340) 207 48.6 2.2e-05 NP_001182310 (OMIM: 602646) G-protein coupled rece ( 340) 207 48.6 2.2e-05 NP_001184113 (OMIM: 610118) probable G-protein cou ( 333) 205 48.2 2.8e-05 NP_006009 (OMIM: 606039) hydroxycarboxylic acid re ( 387) 204 48.1 3.5e-05 XP_005274835 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 200 47.4 5.5e-05 XP_011543933 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 200 47.4 5.5e-05 XP_011544481 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 200 47.4 5.5e-05 XP_011543934 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 200 47.4 5.5e-05 XP_005274486 (OMIM: 300525) PREDICTED: P2Y purinoc ( 359) 200 47.4 5.5e-05 >>NP_002368 (OMIM: 165180) proto-oncogene Mas [Homo sapi (325 aa) initn: 2134 init1: 2134 opt: 2134 Z-score: 2063.0 bits: 390.0 E(85289): 3.6e-108 Smith-Waterman score: 2134; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325) 10 20 30 40 50 60 pF1KE1 MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 MRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 YLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 RNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 AMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLT 250 260 270 280 290 300 310 320 pF1KE1 RAFKDEMQPRRQKDNCNTVTVETVV ::::::::::::::::::::::::: NP_002 RAFKDEMQPRRQKDNCNTVTVETVV 310 320 >>NP_671732 (OMIM: 607227) mas-related G-protein coupled (322 aa) initn: 613 init1: 278 opt: 617 Z-score: 610.4 bits: 121.2 E(85289): 2.9e-27 Smith-Waterman score: 617; 38.3% identity (71.4% similar) in 269 aa overlap (42-305:37-297) 20 30 40 50 60 70 pF1KE1 EEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYIT .: ::.. :...::.: ::::: :..:: NP_671 TLDTELTPINGTEETLCYKQTLSLTVLTCIVSLVGLTGNAVVLWLLGCRMRRNAFSIYIL 10 20 30 40 50 60 80 90 100 110 120 130 pF1KE1 HLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERC .:. ::. .: .: :.: .: : . . : ..:.: .:: .:.:.:.::: NP_671 NLAAADFLFLSGRLI----YSLLSFISIPHTISKILYPV-MMFSYFAGLSFLSAVSTERC 70 80 90 100 110 120 140 150 160 170 180 190 pF1KE1 LSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFI ::::.::::::::: . ::.::.:::::: : . .:...: . . :.. :: NP_671 LSVLWPIWYRCHRPTHLSAVVCVLLWALSLLRSILEWMLC-GFLFSGADSAWCQTSD-FI 130 140 150 160 170 200 210 220 230 240 250 pF1KE1 AILSFLVFTPLMLV-SSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLL .. ..:.: ..: :: .:...: .. ..::..:..:...::. ..:. . ..: NP_671 TV-AWLIFLCVVLCGSSLVLLIRILCGSRKIPLTRLYVTILLTVLVFLLCGLPFGIQFFL 180 190 200 210 220 230 260 270 280 290 300 pF1KE1 YY----EYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDE . . : ..: .:...:..::::::.::::::: .... ...::.:: ::..: NP_671 FLWIHVDREVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDA 240 250 260 270 280 290 310 320 pF1KE1 MQPRRQKDNCNTVTVETVV NP_671 SEVDEGGGQLPEEILELSGSRLEQ 300 310 320 >>NP_473371 (OMIM: 607228) mas-related G-protein coupled (330 aa) initn: 531 init1: 250 opt: 609 Z-score: 602.6 bits: 119.8 E(85289): 7.9e-27 Smith-Waterman score: 609; 37.7% identity (72.2% similar) in 281 aa overlap (32-305:32-306) 10 20 30 40 50 60 pF1KE1 DGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRM ::. ..:. :. ::.: ::..::.: ::: NP_473 DPTTPAWGTESTTVNGNDQALLLLCGKETLIPV--FLILFIALVGLVGNGFVLWLLGFRM 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 RRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLY ::: :.::. :. ::. :..:. :.. :. . : ..... .: .:: NP_473 RRNAFSVYVLSLAGADF-LFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLAGLS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 LLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSR .:...:.:::::::.::::::.::.. ::.::.:::::: :.. .: .: .. : NP_473 MLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDS- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 NDCRAVIIFIAILSFLVFTPLMLVSSTI-LVVKIRKNTWASHSSKLYIVIMVTIIIFLIF . :.. .. : ..:.: ..: .:.. :.:.: .. . ..::..:..:...::. NP_473 GWCQTFDFITA--AWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLC 180 190 200 210 220 230 250 260 270 280 290 pF1KE1 AMPMRLLYLLYYEYWST----FGNLHHISLLFSTINSSANPFIYFFVGSSKKK-RFKES- ..:. . ..: :. : ..: .:...:..::::::.::::::: .:. :... NP_473 GLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPI 240 250 260 270 280 290 300 310 320 pF1KE1 LKVVLTRAFKDEMQPRRQKDNCNTVTVETVV ::..: ::..: NP_473 LKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV 300 310 320 330 >>NP_001290544 (OMIM: 607228) mas-related G-protein coup (330 aa) initn: 531 init1: 250 opt: 609 Z-score: 602.6 bits: 119.8 E(85289): 7.9e-27 Smith-Waterman score: 609; 37.7% identity (72.2% similar) in 281 aa overlap (32-305:32-306) 10 20 30 40 50 60 pF1KE1 DGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRM ::. ..:. :. ::.: ::..::.: ::: NP_001 DPTTPAWGTESTTVNGNDQALLLLCGKETLIPV--FLILFIALVGLVGNGFVLWLLGFRM 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 RRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLY ::: :.::. :. ::. :..:. :.. :. . : ..... .: .:: NP_001 RRNAFSVYVLSLAGADF-LFLCFQIINCLVYLSNFFCSISINFPSFFTTVMTCAYLAGLS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 LLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSR .:...:.:::::::.::::::.::.. ::.::.:::::: :.. .: .: .. : NP_001 MLSTVSTERCLSVLWPIWYRCRRPRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDS- 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 NDCRAVIIFIAILSFLVFTPLMLVSSTI-LVVKIRKNTWASHSSKLYIVIMVTIIIFLIF . :.. .. : ..:.: ..: .:.. :.:.: .. . ..::..:..:...::. NP_001 GWCQTFDFITA--AWLIFLFMVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLVFLLC 180 190 200 210 220 230 250 260 270 280 290 pF1KE1 AMPMRLLYLLYYEYWST----FGNLHHISLLFSTINSSANPFIYFFVGSSKKK-RFKES- ..:. . ..: :. : ..: .:...:..::::::.::::::: .:. :... NP_001 GLPFGIQWFLILWIWKDSDVLFCHIHPVSVVLSSLNSSANPIIYFFVGSFRKQWRLQQPI 240 250 260 270 280 290 300 310 320 pF1KE1 LKVVLTRAFKDEMQPRRQKDNCNTVTVETVV ::..: ::..: NP_001 LKLALQRALQDIAEVDHSEGCFRQGTPEMSRSSLV 300 310 320 330 >>NP_473373 (OMIM: 607230) mas-related G-protein coupled (322 aa) initn: 603 init1: 261 opt: 605 Z-score: 598.9 bits: 119.1 E(85289): 1.3e-26 Smith-Waterman score: 605; 37.3% identity (69.3% similar) in 306 aa overlap (13-306:2-298) 10 20 30 40 50 pF1KE1 MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIP----IVHWVIMS--ISPVGFVENGILL .:: : . . :.... : . ..... :: ::.. :...: NP_473 MDPTVPVFGTKLTPINGREETPCYNQTLSFTVLTCIISLVGLTGNAVVL 10 20 30 40 60 70 80 90 100 110 pF1KE1 WFLCFRMRRNPFTVYITHLSIADISLLFCIF-ILSIDYALDYELSSGHYYTIVTLSVTFL :.: .::::: ..:: .:. :: .:: : :. . : .. .: . .:: . NP_473 WLLGYRMRRNAVSIYILNLAAAD--FLFLSFQIIRLPLRL---INISHLIRKILVSV-MT 50 60 70 80 90 100 120 130 140 150 160 170 pF1KE1 FGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCID : : ::: .:.:::.:::::::.::::::.:: . ::.::.:::.:: : . .:. .: : NP_473 FPYFTGLSMLSAISTERCLSVLWPIWYRCRRPTHLSAVVCVLLWGLSLLFSMLEWRFC-D 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE1 REEESHSRNDCRAVIIFIAILSFLVFTPLML-VSSTILVVKIRKNTWASHSSKLYIVIMV . . . :.. :: . ..:.: ..: ::: .:.:.: .. ..::..:.. NP_473 FLFSGADSSWCETSD-FIPV-AWLIFLCVVLCVSSLVLLVRILCGSRKMPLTRLYVTILL 170 180 190 200 210 220 240 250 260 270 280 pF1KE1 TIIIFLIFAMPMRLLYLLYYEYWSTFGNLH-HISLL---FSTINSSANPFIYFFVGSSKK :...::. ..:. .: : :.. .. :. :. :. .:..::::::.::::::: .. NP_473 TVLVFLLCGLPFGILGALIYRMHLNLEVLYCHVYLVCMSLSSLNSSANPIIYFFVGSFRQ 230 240 250 260 270 280 290 300 310 320 pF1KE1 KRFKESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV .. ...::.:: ::..:. NP_473 RQNRQNLKLVLQRALQDKPEVDKGEGQLPEESLELSGSRLGP 290 300 310 320 >>NP_944605 (OMIM: 607231) mas-related G-protein coupled (321 aa) initn: 480 init1: 325 opt: 597 Z-score: 591.3 bits: 117.7 E(85289): 3.4e-26 Smith-Waterman score: 597; 34.0% identity (65.1% similar) in 315 aa overlap (1-306:1-303) 10 20 30 40 50 60 pF1KE1 MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFR :. . .: .:: : : : ...: .. . : :.. :....:.: :: NP_944 MNQTLNSSGTVESALNYSRG-----STVHTAYLVLSSLAMFTCLCGMAGNSMVIWLLGFR 10 20 30 40 50 70 80 90 100 110 pF1KE1 MRRNPFTVYITHLSIADISLLFCIF-ILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTG :.:::: .:: .:. ::. .:: . ::.. . .. . . : . :.:..: NP_944 MHRNPFCIYILNLAAADLLFLFSMASTLSLETQPLVNTTDKVHELMKRL---MYFAYTVG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE1 LYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESH : ::::::..::::::.:::..::::.. :: ::.:::.: :.. . .: . .. NP_944 LSLLTAISTQRCLSVLFPIWFKCHRPRHLSAWVCGLLWTLCLLMNGLTSSFCSKFLKFNE 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE1 SRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNT--WASHSSKLYIVIMVTIIIF .: : : . : : . :.::.: .:: : : .:... : . ..:..:.......: NP_944 DR--CFRVDMVQAALIMGVLTPVMTLSSLTLFVWVRRSSQQWRRQPTRLFVVVLASVLVF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE1 LIFAMPMRLLYLLYYEYWSTFGNLHHI-----SLLFSTINSSANPFIYFFVGSSKKKRFK :: ..:. . ... : : .. .. : : :...::::: :::.::: ...:. NP_944 LICSLPLSIYWFVLY--WLSLPPEMQVLCFSLSRLSSSVSSSANPVIYFLVGSRRSHRLP 240 250 260 270 280 300 310 320 pF1KE1 -ESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV .:: .:: .:...: NP_944 TRSLGTVLQQALREEPELEGGETPTVGTNEMGA 290 300 310 320 >>NP_473372 (OMIM: 607229) mas-related G-protein coupled (322 aa) initn: 552 init1: 262 opt: 580 Z-score: 575.0 bits: 114.6 E(85289): 2.7e-25 Smith-Waterman score: 580; 37.9% identity (71.4% similar) in 269 aa overlap (42-305:37-297) 20 30 40 50 60 70 pF1KE1 EEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYIT .: :... :...::.: ::::: ..:: NP_473 VLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVSIYIL 10 20 30 40 50 60 80 90 100 110 120 130 pF1KE1 HLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERC .: ::. .: .: : .. . : . . :: .. : : :: .:.:::.::: NP_473 NLVAADFLFLSGHIICSPLRLINIR----HPISKI-LSPVMTFPYFIGLSMLSAISTERC 70 80 90 100 110 120 140 150 160 170 180 190 pF1KE1 LSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFI ::.:.::::.:.::.: :...:.:::::: : . .:...: : . . :.. :: NP_473 LSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFC-DFLFSGANSVWCETSD-FI 130 140 150 160 170 200 210 220 230 240 250 pF1KE1 AILSFLVFTPLMLV-SSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLL .: ..::: ..: :: .:.:.: .. ..::..:..:...::. ..:. . . : NP_473 TI-AWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWAL 180 190 200 210 220 230 260 270 280 290 300 pF1KE1 YYEY---WST-FGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDE . . :.. : ..: .:...:..::::::.::::::: .... ...::.:: ::..: NP_473 FSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDT 240 250 260 270 280 290 310 320 pF1KE1 MQPRRQKDNCNTVTVETVV NP_473 PEVDEGGGWLPQETLELSGSRLEQ 300 310 320 >>XP_011518184 (OMIM: 607229) PREDICTED: mas-related G-p (322 aa) initn: 552 init1: 262 opt: 580 Z-score: 575.0 bits: 114.6 E(85289): 2.7e-25 Smith-Waterman score: 580; 37.9% identity (71.4% similar) in 269 aa overlap (42-305:37-297) 20 30 40 50 60 70 pF1KE1 EEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYIT .: :... :...::.: ::::: ..:: XP_011 VLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVSIYIL 10 20 30 40 50 60 80 90 100 110 120 130 pF1KE1 HLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERC .: ::. .: .: : .. . : . . :: .. : : :: .:.:::.::: XP_011 NLVAADFLFLSGHIICSPLRLINIR----HPISKI-LSPVMTFPYFIGLSMLSAISTERC 70 80 90 100 110 120 140 150 160 170 180 190 pF1KE1 LSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFI ::.:.::::.:.::.: :...:.:::::: : . .:...: : . . :.. :: XP_011 LSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFC-DFLFSGANSVWCETSD-FI 130 140 150 160 170 200 210 220 230 240 250 pF1KE1 AILSFLVFTPLMLV-SSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLL .: ..::: ..: :: .:.:.: .. ..::..:..:...::. ..:. . . : XP_011 TI-AWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWAL 180 190 200 210 220 230 260 270 280 290 300 pF1KE1 YYEY---WST-FGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDE . . :.. : ..: .:...:..::::::.::::::: .... ...::.:: ::..: XP_011 FSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDT 240 250 260 270 280 290 310 320 pF1KE1 MQPRRQKDNCNTVTVETVV XP_011 PEVDEGGGWLPQETLELSGSRLEQ 300 310 320 >>NP_001091985 (OMIM: 607233) mas-related G-protein coup (343 aa) initn: 559 init1: 343 opt: 571 Z-score: 566.0 bits: 113.1 E(85289): 8.7e-25 Smith-Waterman score: 571; 34.4% identity (65.6% similar) in 291 aa overlap (34-322:46-334) 10 20 30 40 50 60 pF1KE1 SNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRR ....... . :.: ::..:::. : ..: NP_001 KMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIKR 20 30 40 50 60 70 70 80 90 100 110 120 pF1KE1 NPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLL :::..:. ::. ::.. :: ..:: . . . . : : : : . ::. :: NP_001 NPFSIYFLHLASADVGYLFSKAVFSILNTGGFLGTFADYIRSVC-RVLGLCMFLTGVSLL 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE1 TAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRND :.:.::: ::..: :: .::: ::.::::::.:: ::: .. .:. .. NP_001 PAVSAERCASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCV-FLGRGAPGAA 140 150 160 170 180 190 190 200 210 220 230 240 pF1KE1 CRAVIIFIAILSFLVFTPLMLVSSTILVVKIR-KNTWASHSSKLYIVIMVTIIIFLIFAM :: . ::..:: ::. :::.. :..... . ..:.:: ::.. . .::. .. NP_001 CRHMDIFLGILLFLLCCPLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSI 200 210 220 230 240 250 250 260 270 280 290 300 pF1KE1 PMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRA . . ..:.. . .... : :::::.:..::..: .:..:. : :.::. :: NP_001 YLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRA 260 270 280 290 300 310 310 320 pF1KE1 FKDEMQPRRQKDNC-NTVTVETVV ..: . . . ::::.: NP_001 LRDGAELGEAGGSTPNTVTMEMQCPPGNAS 320 330 340 >>XP_016872659 (OMIM: 607233) PREDICTED: mas-related G-p (343 aa) initn: 559 init1: 343 opt: 571 Z-score: 566.0 bits: 113.1 E(85289): 8.7e-25 Smith-Waterman score: 571; 34.4% identity (65.6% similar) in 291 aa overlap (34-322:46-334) 10 20 30 40 50 60 pF1KE1 SNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRR ....... . :.: ::..:::. : ..: XP_016 KMCPGLSEAPELYSRGFLTIEQIAMLPPPAVMNYIFLLLCLCGLVGNGLVLWFFGFSIKR 20 30 40 50 60 70 70 80 90 100 110 120 pF1KE1 NPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLL :::..:. ::. ::.. :: ..:: . . . . : : : : . ::. :: XP_016 NPFSIYFLHLASADVGYLFSKAVFSILNTGGFLGTFADYIRSVC-RVLGLCMFLTGVSLL 80 90 100 110 120 130 130 140 150 160 170 180 pF1KE1 TAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRND :.:.::: ::..: :: .::: ::.::::::.:: ::: .. .:. .. XP_016 PAVSAERCASVIFPAWYWRRRPKRLSAVVCALLWVLSLLVTCLHNYFCV-FLGRGAPGAA 140 150 160 170 180 190 190 200 210 220 230 240 pF1KE1 CRAVIIFIAILSFLVFTPLMLVSSTILVVKIR-KNTWASHSSKLYIVIMVTIIIFLIFAM :: . ::..:: ::. :::.. :..... . ..:.:: ::.. . .::. .. XP_016 CRHMDIFLGILLFLLCCPLMVLPCLALILHVECRARRRQRSAKLNHVILAMVSVFLVSSI 200 210 220 230 240 250 250 260 270 280 290 300 pF1KE1 PMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRA . . ..:.. . .... : :::::.:..::..: .:..:. : :.::. :: XP_016 YLGIDWFLFWVFQIPAPFPEYVTDLCICINSSAKPIVYFLAGRDKSQRLWEPLRVVFQRA 260 270 280 290 300 310 310 320 pF1KE1 FKDEMQPRRQKDNC-NTVTVETVV ..: . . . ::::.: XP_016 LRDGAELGEAGGSTPNTVTMEMQCPPGNAS 320 330 340 325 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 03:26:17 2016 done: Mon Nov 7 03:26:18 2016 Total Scan time: 6.050 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]