Result of FASTA (omim) for
pF1KE1860
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1860, 380 aa
1>>>pF1KE1860 380 - 380 aa - 380 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.1558+/-0.000467; mu= -30.6875+/- 0.029
mean_var=811.1343+/-167.826, 0's: 0 Z-trim(126.6): 35 B-trim: 965 in 1/61
Lambda= 0.045033
statistics sampled from 52774 (52817) to 52774 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.847), E-opt: 0.2 (0.619), width: 16
Scan time: 11.180
The best scores are: opt bits E(85289)
NP_003361 (OMIM: 601703) vasodilator-stimulated ph ( 380) 2636 185.7 1.6e-46
XP_005259257 (OMIM: 601703) PREDICTED: vasodilator ( 379) 2617 184.4 3.7e-46
XP_005259256 (OMIM: 601703) PREDICTED: vasodilator ( 379) 2617 184.4 3.7e-46
XP_016882689 (OMIM: 601703) PREDICTED: vasodilator ( 378) 2598 183.2 8.6e-46
NP_001317150 (OMIM: 616912) ena/VASP-like protein ( 416) 958 76.7 1.1e-13
NP_057421 (OMIM: 616912) ena/VASP-like protein iso ( 418) 951 76.2 1.5e-13
XP_005267806 (OMIM: 616912) PREDICTED: ena/VASP-li ( 422) 951 76.2 1.5e-13
XP_016876852 (OMIM: 616912) PREDICTED: ena/VASP-li ( 429) 943 75.7 2.2e-13
XP_011535130 (OMIM: 616912) PREDICTED: ena/VASP-li ( 370) 940 75.5 2.3e-13
NP_060682 (OMIM: 609061) protein enabled homolog i ( 570) 585 52.6 2.7e-06
NP_001008493 (OMIM: 609061) protein enabled homolo ( 591) 585 52.6 2.8e-06
XP_005273244 (OMIM: 609061) PREDICTED: protein ena ( 605) 578 52.2 3.9e-06
XP_016857241 (OMIM: 609061) PREDICTED: protein ena ( 795) 578 52.3 4.8e-06
XP_016857240 (OMIM: 609061) PREDICTED: protein ena ( 832) 578 52.3 4.9e-06
XP_016857237 (OMIM: 609061) PREDICTED: protein ena ( 853) 578 52.3 5e-06
XP_016857245 (OMIM: 609061) PREDICTED: protein ena ( 578) 534 49.3 2.7e-05
XP_016857246 (OMIM: 609061) PREDICTED: protein ena ( 578) 534 49.3 2.7e-05
XP_016857238 (OMIM: 609061) PREDICTED: protein ena ( 851) 530 49.2 4.3e-05
XP_011542531 (OMIM: 609061) PREDICTED: protein ena ( 872) 530 49.2 4.4e-05
XP_016857243 (OMIM: 609061) PREDICTED: protein ena ( 614) 520 48.4 5.4e-05
XP_016857242 (OMIM: 609061) PREDICTED: protein ena ( 628) 513 47.9 7.5e-05
XP_016857239 (OMIM: 609061) PREDICTED: protein ena ( 839) 513 48.1 9.2e-05
XP_016857236 (OMIM: 609061) PREDICTED: protein ena ( 855) 513 48.1 9.4e-05
XP_016857235 (OMIM: 609061) PREDICTED: protein ena ( 876) 513 48.1 9.5e-05
XP_016857244 (OMIM: 609061) PREDICTED: protein ena ( 601) 469 45.1 0.00053
>>NP_003361 (OMIM: 601703) vasodilator-stimulated phosph (380 aa)
initn: 2636 init1: 2636 opt: 2636 Z-score: 956.4 bits: 185.7 E(85289): 1.6e-46
Smith-Waterman score: 2636; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
310 320 330 340 350 360
370 380
pF1KE1 KVKEEIIEAFVQELRKRGSP
::::::::::::::::::::
NP_003 KVKEEIIEAFVQELRKRGSP
370 380
>>XP_005259257 (OMIM: 601703) PREDICTED: vasodilator-sti (379 aa)
initn: 2077 init1: 2077 opt: 2617 Z-score: 949.7 bits: 184.4 E(85289): 3.7e-46
Smith-Waterman score: 2617; 99.7% identity (99.7% similar) in 380 aa overlap (1-380:1-379)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_005 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESAN-EEPEARVP
250 260 270 280 290
310 320 330 340 350 360
pF1KE1 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
300 310 320 330 340 350
370 380
pF1KE1 KVKEEIIEAFVQELRKRGSP
::::::::::::::::::::
XP_005 KVKEEIIEAFVQELRKRGSP
360 370
>>XP_005259256 (OMIM: 601703) PREDICTED: vasodilator-sti (379 aa)
initn: 1780 init1: 1780 opt: 2617 Z-score: 949.7 bits: 184.4 E(85289): 3.7e-46
Smith-Waterman score: 2617; 99.7% identity (99.7% similar) in 380 aa overlap (1-380:1-379)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 -EEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
250 260 270 280 290
310 320 330 340 350 360
pF1KE1 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
300 310 320 330 340 350
370 380
pF1KE1 KVKEEIIEAFVQELRKRGSP
::::::::::::::::::::
XP_005 KVKEEIIEAFVQELRKRGSP
360 370
>>XP_016882689 (OMIM: 601703) PREDICTED: vasodilator-sti (378 aa)
initn: 1780 init1: 1780 opt: 2598 Z-score: 943.1 bits: 183.2 E(85289): 8.6e-46
Smith-Waterman score: 2598; 99.5% identity (99.5% similar) in 380 aa overlap (1-380:1-378)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPALPTWSVPNGPSPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGGAGAPGLAAAIAGAKLRKVSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 QEEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVP
:::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 -EEASGGPTAPKAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESAN-EEPEARVP
250 260 270 280 290
310 320 330 340 350 360
pF1KE1 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSESVRRPWEKNSTTLPRMKSSSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQ
300 310 320 330 340 350
370 380
pF1KE1 KVKEEIIEAFVQELRKRGSP
::::::::::::::::::::
XP_016 KVKEEIIEAFVQELRKRGSP
360 370
>>NP_001317150 (OMIM: 616912) ena/VASP-like protein isof (416 aa)
initn: 338 init1: 338 opt: 958 Z-score: 366.7 bits: 76.7 E(85289): 1.1e-13
Smith-Waterman score: 1100; 48.1% identity (67.5% similar) in 428 aa overlap (1-374:1-410)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::: ::..::.::.::: .:.:.: : :.:::..:::: ..:.::::: :.: ::::
NP_001 MSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQQV
10 20 30 40 50
70 80 90 100 110
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEG--GGP
::: .::.:.:::::::.::::::::::.::::.:::.:. :. .: ::. ... :::
NP_001 VINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 PPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAPPAGGPP
.: :::::.:.. :.:: : .: .:::.: .: ::. :...
NP_001 SSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSAAS
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 PP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGGAGAPGL
: :::::: :: :: ::.:. ::: ::::: ::: . .. ::
NP_001 APVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDESSMSGL
180 190 200 210 220
230 240 250 260 270
pF1KE1 AAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLARRRKA-
::::::::::.:.. :.:::: :. : .: :: .:::::::::: .::.::::
NP_001 AAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLAKRRKAA
230 240 250 260 270 280
280 290 300 310 320
pF1KE1 TQVGEKTPKDESANQEE-------PEARV----PAQSESVRRPWEK-NSTTLPR---MKS
.: . . : :. .: : : .:. : .::. :.:::. ::. : ..
NP_001 SQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSILSR
290 300 310 320 330 340
330 340 350 360
pF1KE1 SSSVTTS-------ETQPCT---PSSS------DYSDLQRVKQELLEEVKKELQKVKEEI
. ::. : ..:: . :..: : ::.:.:::.:::: .::.::::::
NP_001 TPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKEEI
350 360 370 380 390 400
370 380
pF1KE1 IEAFVQELRKRGSP
:.:. :::
NP_001 IDAIRQELSGISTT
410
>>NP_057421 (OMIM: 616912) ena/VASP-like protein isoform (418 aa)
initn: 338 init1: 338 opt: 951 Z-score: 364.2 bits: 76.2 E(85289): 1.5e-13
Smith-Waterman score: 1093; 48.0% identity (67.4% similar) in 427 aa overlap (2-374:4-412)
10 20 30 40 50
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQ
:: ::..::.::.::: .:.:.: : :.:::..:::: ..:.::::: :.: ::
NP_057 MATSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQ-DQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEG--G
::::: .::.:.:::::::.::::::::::.::::.:::.:. :. .: ::. ... :
NP_057 QVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMNSQEG
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 GPPPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAPPAGG
:: .: :::::.:.. :.:: : .: .:::.: .: ::. :...
NP_057 GPSSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHPSSA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 PPPP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGGAGAP
: :::::: :: :: ::.:. ::: ::::: ::: . ..
NP_057 ASAPVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDESSMS
180 190 200 210 220
230 240 250 260 270
pF1KE1 GLAAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLARRRK
::::::::::::.:.. :.:::: :. : .: :: .:::::::::: .::.:::
NP_057 GLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLAKRRK
230 240 250 260 270 280
280 290 300 310 320
pF1KE1 A-TQVGEKTPKDESANQEE-------PEARV----PAQSESVRRPWEK-NSTTLPR---M
: .: . . : :. .: : : .:. : .::. :.:::. ::. : .
NP_057 AASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPVSSIL
290 300 310 320 330 340
330 340 350 360
pF1KE1 KSSSSVTTS-------ETQPCT---PSSS------DYSDLQRVKQELLEEVKKELQKVKE
. . ::. : ..:: . :..: : ::.:.:::.:::: .::.::::
NP_057 SRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELHKVKE
350 360 370 380 390 400
370 380
pF1KE1 EIIEAFVQELRKRGSP
:::.:. :::
NP_057 EIIDAIRQELSGISTT
410
>>XP_005267806 (OMIM: 616912) PREDICTED: ena/VASP-like p (422 aa)
initn: 338 init1: 338 opt: 951 Z-score: 364.1 bits: 76.2 E(85289): 1.5e-13
Smith-Waterman score: 1093; 48.0% identity (67.4% similar) in 427 aa overlap (2-374:8-416)
10 20 30 40 50
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKM
:: ::..::.::.::: .:.:.: : :.:::..:::: ..:.::::: :.
XP_005 MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE
: ::::::: .::.:.:::::::.::::::::::.::::.:::.:. :. .: ::. ..
XP_005 Q-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN
70 80 90 100 110
120 130 140 150 160
pF1KE1 G--GGPPPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAP
. ::: .: :::::.:.. :.:: : .: .:::.: .: ::.
XP_005 SQEGGPSSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 PAGGPPPP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGG
:... : :::::: :: :: ::.:. ::: ::::: ::: .
XP_005 PSSAASAPVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDE
180 190 200 210 220
230 240 250 260 270
pF1KE1 AGAPGLAAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLA
.. ::::::::::::.:.. :.:::: :. : .: :: .:::::::::: .::
XP_005 SSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLA
230 240 250 260 270 280
280 290 300 310
pF1KE1 RRRKA-TQVGEKTPKDESANQEE-------PEARV----PAQSESVRRPWEK-NSTTLPR
.:::: .: . . : :. .: : : .:. : .::. :.:::. ::. :
XP_005 KRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNSVEKPV
290 300 310 320 330 340
320 330 340 350 360
pF1KE1 ---MKSSSSVTTS-------ETQPCT---PSSS------DYSDLQRVKQELLEEVKKELQ
.. . ::. : ..:: . :..: : ::.:.:::.:::: .::.
XP_005 SSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEVVRELH
350 360 370 380 390 400
370 380
pF1KE1 KVKEEIIEAFVQELRKRGSP
:::::::.:. :::
XP_005 KVKEEIIDAIRQELSGISTT
410 420
>>XP_016876852 (OMIM: 616912) PREDICTED: ena/VASP-like p (429 aa)
initn: 667 init1: 338 opt: 943 Z-score: 361.2 bits: 75.7 E(85289): 2.2e-13
Smith-Waterman score: 961; 49.0% identity (68.1% similar) in 351 aa overlap (2-325:8-339)
10 20 30 40 50
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKM
:: ::..::.::.::: .:.:.: : :.:::..:::: ..:.::::: :.
XP_016 MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE
: ::::::: .::.:.:::::::.::::::::::.::::.:::.:. :. .: ::. ..
XP_016 Q-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN
70 80 90 100 110
120 130 140 150 160
pF1KE1 G--GGPPPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAP
. ::: .: :::::.:.. :.:: : .: .:::.: .: ::.
XP_016 SQEGGPSSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 PAGGPPPP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGG
:... : :::::: :: :: ::.:. ::: ::::: ::: .
XP_016 PSSAASAPVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDE
180 190 200 210 220
230 240 250 260 270
pF1KE1 AGAPGLAAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLA
.. ::::::::::::.:.. :.:::: :. : .: :: .:::::::::: .::
XP_016 SSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLA
230 240 250 260 270 280
280 290 300 310 320
pF1KE1 RRRKA-TQVGEKTPKDESANQ----EEPEARVPAQSESVRRPWEKNSTTLPRMKSSSSVT
.:::: .: . . : :. .: : : ... . :: :.. :: : : :. :
XP_016 KRRKAASQSDKPAEKKEDESQMGYLAFPGAPGSTDQPGSRRDWDSRST-LQRGTSARSPE
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE1 TSETQPCTPSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSP
XP_016 RKILVPPPLRGPEQPASHLTPQRLAGSPGSGATRWRSLCPRFCPEPRLWQRAPKLRAPFS
350 360 370 380 390 400
>>XP_011535130 (OMIM: 616912) PREDICTED: ena/VASP-like p (370 aa)
initn: 667 init1: 338 opt: 940 Z-score: 361.0 bits: 75.5 E(85289): 2.3e-13
Smith-Waterman score: 961; 49.0% identity (68.1% similar) in 351 aa overlap (2-325:8-339)
10 20 30 40 50
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKM
:: ::..::.::.::: .:.:.: : :.:::..:::: ..:.::::: :.
XP_011 MFAFEEFSEQSICQARASVMVYDDTSKKWVPIKPGQQGFSRINIYHNTASNTFRVVGVKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 QPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE
: ::::::: .::.:.:::::::.::::::::::.::::.:::.:. :. .: ::. ..
XP_011 Q-DQQVVINYSIVKGLKYNQATPTFHQWRDARQVYGLNFASKEEATTFSNAMLFALNIMN
70 80 90 100 110
120 130 140 150 160
pF1KE1 G--GGPPPPPALPTWSVPNGPSPEEVEQQKRQ-----QPGPSEHIERRVSNAGG--PPAP
. ::: .: :::::.:.. :.:: : .: .:::.: .: ::.
XP_011 SQEGGPSSQR-----QVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 PAGGPPPP---PGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPA--AQGPGGGG
:... : :::::: :: :: ::.:. ::: ::::: ::: .
XP_011 PSSAASAPVSCSGPPPPPPPPVPP--PPTGAT---------PPPPPPLPAGGAQGSSHDE
180 190 200 210 220
230 240 250 260 270
pF1KE1 AGAPGLAAAIAGAKLRKVSKQEEASGG--PT------APKAESGRSGGGGLMEEMNAMLA
.. ::::::::::::.:.. :.:::: :. : .: :: .:::::::::: .::
XP_011 SSMSGLAAAIAGAKLRRVQRPEDASGGSSPSGTSKSDANRASSG-GGGGGLMEEMNKLLA
230 240 250 260 270 280
280 290 300 310 320
pF1KE1 RRRKA-TQVGEKTPKDESANQ----EEPEARVPAQSESVRRPWEKNSTTLPRMKSSSSVT
.:::: .: . . : :. .: : : ... . :: :.. :: : : :. :
XP_011 KRRKAASQSDKPAEKKEDESQMGYLAFPGAPGSTDQPGSRRDWDSRST-LQRGTSARSPE
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE1 TSETQPCTPSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQELRKRGSP
XP_011 RPRDNHRHQNTVASLQPQPWGSEDIAGLS
350 360 370
>>NP_060682 (OMIM: 609061) protein enabled homolog isofo (570 aa)
initn: 1012 init1: 281 opt: 585 Z-score: 233.9 bits: 52.6 E(85289): 2.7e-06
Smith-Waterman score: 594; 37.1% identity (47.1% similar) in 412 aa overlap (1-243:1-409)
10 20 30 40 50 60
pF1KE1 MSETVICSSRATVMLYDDGNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQV
::: ::..::.::.:::.::.:.::: : .::::.:::. :.:::::::.: :.::
NP_060 MSEQSICQARAAVMVYDDANKKWVPAG-GSTGFSRVHIYHHTGNNTFRVVGRKIQ-DHQV
10 20 30 40 50
70 80 90 100 110
pF1KE1 VINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGG--GP
:::::: .:.:::::: .::::::::::.:::::::::: ::..: :::.:.. ::
NP_060 VINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQETGP
60 70 80 90 100 110
120 130 140 150
pF1KE1 PPP---PALPTWSVPNGPSPEEVE-------QQKRQQPGPSEHIER--------------
: ::. .: :::: ::.: .:.::. :..::
NP_060 TLPRQNSQLPA-QVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLE
120 130 140 150 160 170
pF1KE1 ------------------------------------------------------------
NP_060 RERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLER
180 190 200 210 220 230
160
pF1KE1 -------------------------RVSNAGGP--------------------------P
:.:.:..: :
NP_060 LERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQP
240 250 260 270 280 290
170 180 190 200
pF1KE1 A-----------PPAGGPPPP--PGP-------PPPPGPPPPPGLPPSGVPAAAHGA---
: : : :::: ::: :::::::::: :: .: :
NP_060 AETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLP
300 310 320 330 340 350
210 220 230 240 250
pF1KE1 GGGPPPAPPLPAAQGPGGGGAGA-------P--GLAAAIAGAKLRKVSKQEEASGGPTAP
. ::: :: :: :..: : : :::::::::::::::..:.
NP_060 NQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGN
360 370 380 390 400 410
260 270 280 290 300 310
pF1KE1 KAESGRSGGGGLMEEMNAMLARRRKATQVGEKTPKDESANQEEPEARVPAQSESVRRPWE
NP_060 AIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDS
420 430 440 450 460 470
380 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:09:58 2016 done: Sun Nov 6 12:09:59 2016
Total Scan time: 11.180 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]