FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1861, 380 aa 1>>>pF1KE1861 380 - 380 aa - 380 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2521+/-0.00037; mu= 17.6680+/- 0.023 mean_var=84.7819+/-17.285, 0's: 0 Z-trim(113.6): 65 B-trim: 89 in 2/51 Lambda= 0.139291 statistics sampled from 23952 (24017) to 23952 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.26), width: 16 Scan time: 3.900 The best scores are: opt bits E(92320) NP_003383 (OMIM: 164975,180700) protein Wnt-5a iso ( 380) 2662 545.0 1.1e-154 XP_016862616 (OMIM: 164975,180700) protein Wnt-5a ( 394) 2650 542.6 6.2e-154 XP_011532391 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_011532387 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_006713387 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_011532388 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_011532390 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_016862617 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_011532389 (OMIM: 164975,180700) protein Wnt-5a ( 365) 2569 526.3 4.6e-149 XP_024304972 (OMIM: 606361) protein Wnt-5b isoform ( 380) 2129 437.9 2e-122 XP_024304971 (OMIM: 606361) protein Wnt-5b isoform ( 411) 2129 438.0 2.1e-122 XP_024304973 (OMIM: 606361) protein Wnt-5b isoform ( 359) 2125 437.1 3.3e-122 XP_024304975 (OMIM: 606361) protein Wnt-5b isoform ( 359) 2125 437.1 3.3e-122 NP_110402 (OMIM: 606361) protein Wnt-5b precursor ( 359) 2125 437.1 3.3e-122 XP_024304976 (OMIM: 606361) protein Wnt-5b isoform ( 359) 2125 437.1 3.3e-122 XP_024304974 (OMIM: 606361) protein Wnt-5b isoform ( 359) 2125 437.1 3.3e-122 XP_024304977 (OMIM: 606361) protein Wnt-5b isoform ( 359) 2125 437.1 3.3e-122 NP_116031 (OMIM: 606361) protein Wnt-5b precursor ( 359) 2125 437.1 3.3e-122 NP_078613 (OMIM: 601968,618168) protein Wnt-2b iso ( 391) 1236 258.5 2.1e-68 NP_004176 (OMIM: 601968,618168) protein Wnt-2b iso ( 372) 1234 258.1 2.7e-68 NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 1215 254.2 3.6e-67 NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 1214 254.0 4.3e-67 XP_011539899 (OMIM: 158330,603490,611812) protein ( 373) 1207 252.6 1.2e-66 XP_011528668 (OMIM: 601967) protein Wnt-7b isoform ( 353) 1184 248.0 2.7e-65 NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 1183 247.8 3.1e-65 NP_001278809 (OMIM: 601968,618168) protein Wnt-2b ( 299) 1158 242.7 9.1e-64 XP_011539900 (OMIM: 158330,603490,611812) protein ( 296) 1157 242.5 1e-63 NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 1140 239.2 1.2e-62 NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 1130 237.1 5.1e-62 NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 1128 236.7 6.7e-62 XP_011542621 (OMIM: 606359) protein Wnt-3a isoform ( 446) 1128 236.8 8e-62 XP_011532393 (OMIM: 228930,276820,601570) protein ( 282) 1039 218.8 1.4e-56 NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 993 209.6 9.9e-54 NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 990 209.0 1.5e-53 XP_005274288 (OMIM: 603699) protein Wnt-11 isoform ( 354) 950 201.0 3.9e-51 NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 950 201.0 3.9e-51 XP_011543540 (OMIM: 603699) protein Wnt-11 isoform ( 364) 921 195.2 2.3e-49 XP_011543542 (OMIM: 603699) protein Wnt-11 isoform ( 364) 921 195.2 2.3e-49 XP_011543541 (OMIM: 603699) protein Wnt-11 isoform ( 364) 921 195.2 2.3e-49 NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 861 183.1 9.5e-46 NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 854 181.7 2.5e-45 NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 854 181.7 2.6e-45 XP_016865314 (OMIM: 606360) protein Wnt-8a isoform ( 391) 854 181.7 2.7e-45 NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 831 177.1 6.6e-44 XP_016865313 (OMIM: 606360) protein Wnt-8a isoform ( 408) 831 177.1 6.9e-44 NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 743 159.4 1.4e-38 XP_011541927 (OMIM: 606360) protein Wnt-8a isoform ( 337) 716 153.9 5.4e-37 XP_024304947 (OMIM: 225300,601906,617073) protein ( 267) 669 144.4 3.2e-34 XP_016875408 (OMIM: 225300,601906,617073) protein ( 267) 669 144.4 3.2e-34 >>NP_003383 (OMIM: 164975,180700) protein Wnt-5a isoform (380 aa) initn: 2662 init1: 2662 opt: 2662 Z-score: 2898.5 bits: 545.0 E(92320): 1.1e-154 Smith-Waterman score: 2662; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 310 320 330 340 350 360 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: NP_003 WCCYVKCKKCTEIVDQFVCK 370 380 >>XP_016862616 (OMIM: 164975,180700) protein Wnt-5a isof (394 aa) initn: 2650 init1: 2650 opt: 2650 Z-score: 2885.2 bits: 542.6 E(92320): 6.2e-154 Smith-Waterman score: 2650; 99.7% identity (100.0% similar) in 379 aa overlap (2-380:16-394) 10 20 30 40 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSW .:::::::::::::::::::::::::::::::::::::::::::: XP_016 MHPTTQVPTTLGTLQEKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSW 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 WSLGMNNPVQMSEVYIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSLGMNNPVQMSEVYIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQY 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE1 QFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFRHRRWNCSTVDNTSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSR 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE1 AARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AARPKDLPRDWLWGGCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAG 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE1 RRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRTVYNLADVACKCHGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQ 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE1 VNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNSRFNSPTTQDLVYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQ 310 320 330 340 350 360 350 360 370 380 pF1KE1 FKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK :::::::::::::::::::::::::::::::::: XP_016 FKTVQTERCHCKFHWCCYVKCKKCTEIVDQFVCK 370 380 390 >>XP_011532391 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_011 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_011532387 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_011 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_006713387 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_006 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_011532388 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_011 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_011532390 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_011 WCCYVKCKKCTEIVDQFVCK 350 360 >>NP_001243034 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: NP_001 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_016862617 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_016 WCCYVKCKKCTEIVDQFVCK 350 360 >>XP_011532389 (OMIM: 164975,180700) protein Wnt-5a isof (365 aa) initn: 2569 init1: 2569 opt: 2569 Z-score: 2797.7 bits: 526.3 E(92320): 4.6e-149 Smith-Waterman score: 2569; 100.0% identity (100.0% similar) in 365 aa overlap (16-380:1-365) 10 20 30 40 50 60 pF1KE1 MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV ::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV 10 20 30 40 70 80 90 100 110 120 pF1KE1 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KE1 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KE1 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE1 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE1 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH 290 300 310 320 330 340 370 380 pF1KE1 WCCYVKCKKCTEIVDQFVCK :::::::::::::::::::: XP_011 WCCYVKCKKCTEIVDQFVCK 350 360 380 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:52:58 2019 done: Thu Oct 24 21:52:58 2019 Total Scan time: 3.900 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]