FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1875, 398 aa 1>>>pF1KE1875 398 - 398 aa - 398 aa Library: /omim/omim.rfq.tfa 62246620 residues in 87639 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6747+/-0.000329; mu= 2.9366+/- 0.021 mean_var=186.7181+/-37.854, 0's: 0 Z-trim(121.3): 36 B-trim: 2151 in 1/54 Lambda= 0.093860 statistics sampled from 38131 (38167) to 38131 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.436), width: 16 Scan time: 10.160 The best scores are: opt bits E(87639) NP_001488 (OMIM: 137060,607091) beta-1,4-galactosy ( 398) 2723 380.6 3.7e-105 XP_005251497 (OMIM: 137060,607091) PREDICTED: beta ( 357) 1902 269.4 1e-71 XP_016858206 (OMIM: 604013) PREDICTED: beta-1,4-ga ( 372) 1339 193.2 9.2e-49 NP_001005417 (OMIM: 604013) beta-1,4-galactosyltra ( 372) 1339 193.2 9.2e-49 XP_016858205 (OMIM: 604013) PREDICTED: beta-1,4-ga ( 372) 1339 193.2 9.2e-49 NP_003771 (OMIM: 604013) beta-1,4-galactosyltransf ( 372) 1339 193.2 9.2e-49 NP_085076 (OMIM: 604013) beta-1,4-galactosyltransf ( 401) 1339 193.2 9.7e-49 NP_003770 (OMIM: 604014) beta-1,4-galactosyltransf ( 393) 1122 163.8 6.7e-40 XP_005245623 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 393) 1122 163.8 6.7e-40 NP_001186803 (OMIM: 604014) beta-1,4-galactosyltra ( 393) 1122 163.8 6.7e-40 NP_001186802 (OMIM: 604014) beta-1,4-galactosyltra ( 393) 1122 163.8 6.7e-40 XP_011508395 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 310) 983 144.9 2.6e-34 XP_016858203 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 310) 983 144.9 2.6e-34 NP_997708 (OMIM: 604015) beta-1,4-galactosyltransf ( 344) 937 138.7 2.1e-32 NP_003769 (OMIM: 604015) beta-1,4-galactosyltransf ( 344) 937 138.7 2.1e-32 XP_006713863 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 XP_006713862 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 XP_011511562 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 XP_005247912 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 XP_006713864 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 XP_006713861 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 344) 937 138.7 2.1e-32 NP_004767 (OMIM: 604016) beta-1,4-galactosyltransf ( 388) 833 124.7 4e-28 NP_001317499 (OMIM: 604017) beta-1,4-galactosyltra ( 343) 788 118.5 2.5e-26 XP_006722642 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 338) 780 117.5 5.2e-26 XP_016881578 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 338) 780 117.5 5.2e-26 XP_005258444 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 370) 780 117.5 5.6e-26 NP_004766 (OMIM: 604017) beta-1,4-galactosyltransf ( 382) 780 117.5 5.7e-26 XP_006722641 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 344) 746 112.9 1.3e-24 XP_016881580 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 269) 696 106.0 1.1e-22 XP_016881579 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 274) 696 106.0 1.2e-22 XP_016858204 (OMIM: 604014) PREDICTED: beta-1,4-ga ( 227) 623 96.1 9.4e-20 XP_016881581 (OMIM: 604017) PREDICTED: beta-1,4-ga ( 202) 602 93.2 6.1e-19 XP_016862890 (OMIM: 604015) PREDICTED: beta-1,4-ga ( 303) 541 85.1 2.6e-16 NP_009186 (OMIM: 130070,604327) beta-1,4-galactosy ( 327) 430 70.0 9.3e-12 XP_016864488 (OMIM: 130070,604327) PREDICTED: beta ( 213) 356 59.9 6.8e-09 XP_006714879 (OMIM: 130070,604327) PREDICTED: beta ( 167) 252 45.8 9.7e-05 >>NP_001488 (OMIM: 137060,607091) beta-1,4-galactosyltra (398 aa) initn: 2723 init1: 2723 opt: 2723 Z-score: 2009.1 bits: 380.6 E(87639): 3.7e-105 Smith-Waterman score: 2723; 100.0% identity (100.0% similar) in 398 aa overlap (1-398:1-398) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 YTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 NGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIA 310 320 330 340 350 360 370 380 390 pF1KE1 HTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS :::::::::::::::::::::::::::::::::::::: NP_001 HTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS 370 380 390 >>XP_005251497 (OMIM: 137060,607091) PREDICTED: beta-1,4 (357 aa) initn: 1902 init1: 1902 opt: 1902 Z-score: 1408.9 bits: 269.4 E(87639): 1e-71 Smith-Waterman score: 2332; 89.7% identity (89.7% similar) in 398 aa overlap (1-398:1-357) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 YTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLTI :::::::::::::::::::::::::::::::::::::: XP_005 YTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGF---------------------- 250 260 270 310 320 330 340 350 360 pF1KE1 NGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIA ::::::::::::::::::::::::::::::::::::::::: XP_005 -------------------RLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRIA 280 290 300 310 370 380 390 pF1KE1 HTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS :::::::::::::::::::::::::::::::::::::: XP_005 HTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS 320 330 340 350 >>XP_016858206 (OMIM: 604013) PREDICTED: beta-1,4-galact (372 aa) initn: 1323 init1: 809 opt: 1339 Z-score: 996.7 bits: 193.2 E(87639): 9.2e-49 Smith-Waterman score: 1366; 54.0% identity (74.2% similar) in 383 aa overlap (16-397:6-365) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :..:.:.:. .. .: ::. :... :. :. .:. : XP_016 MSRLLGGTLERVCKAVLLLCLLHFLVAVILYF---DV-YAQHLAFFSRFS 10 20 30 40 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP : : . ::. .. .:: ..:. :. : .. ::: XP_016 ARGPAHALHPAASSSSSSSNCSRPNATASSSGLPE-------VPSALPGP---------- 50 60 70 80 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :: .:: ::. : ::: .::::. :. :: : ..::.: :::::.: ::. . ::. XP_016 --TAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLMGGRYTPPDCTPAQTVAV 90 100 110 120 130 140 190 200 210 220 230 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALK-DY :::::.:..::.:::.::::.:.::.: ::.::::: :. ::::::::::: :::: : XP_016 IIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE1 DYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT : ::.::::::.::.:.: ::: .::::...::::::: :::. ::::::.::: ::: XP_016 AYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLR 210 220 230 240 250 260 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI ::::::.::::::::::::::. . ::.::::. .:: :::.:.:::.:::::::: .: XP_016 INGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKI 270 280 290 300 310 320 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS .:: :: ::..:. ::::.:.: ::.:.:::::: : XP_016 QNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG 330 340 350 360 370 >>NP_001005417 (OMIM: 604013) beta-1,4-galactosyltransfe (372 aa) initn: 1323 init1: 809 opt: 1339 Z-score: 996.7 bits: 193.2 E(87639): 9.2e-49 Smith-Waterman score: 1366; 54.0% identity (74.2% similar) in 383 aa overlap (16-397:6-365) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :..:.:.:. .. .: ::. :... :. :. .:. : NP_001 MSRLLGGTLERVCKAVLLLCLLHFLVAVILYF---DV-YAQHLAFFSRFS 10 20 30 40 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP : : . ::. .. .:: ..:. :. : .. ::: NP_001 ARGPAHALHPAASSSSSSSNCSRPNATASSSGLPE-------VPSALPGP---------- 50 60 70 80 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :: .:: ::. : ::: .::::. :. :: : ..::.: :::::.: ::. . ::. NP_001 --TAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLMGGRYTPPDCTPAQTVAV 90 100 110 120 130 140 190 200 210 220 230 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALK-DY :::::.:..::.:::.::::.:.::.: ::.::::: :. ::::::::::: :::: : NP_001 IIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE1 DYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT : ::.::::::.::.:.: ::: .::::...::::::: :::. ::::::.::: ::: NP_001 AYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLR 210 220 230 240 250 260 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI ::::::.::::::::::::::. . ::.::::. .:: :::.:.:::.:::::::: .: NP_001 INGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKI 270 280 290 300 310 320 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS .:: :: ::..:. ::::.:.: ::.:.:::::: : NP_001 QNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG 330 340 350 360 370 >>XP_016858205 (OMIM: 604013) PREDICTED: beta-1,4-galact (372 aa) initn: 1323 init1: 809 opt: 1339 Z-score: 996.7 bits: 193.2 E(87639): 9.2e-49 Smith-Waterman score: 1366; 54.0% identity (74.2% similar) in 383 aa overlap (16-397:6-365) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :..:.:.:. .. .: ::. :... :. :. .:. : XP_016 MSRLLGGTLERVCKAVLLLCLLHFLVAVILYF---DV-YAQHLAFFSRFS 10 20 30 40 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP : : . ::. .. .:: ..:. :. : .. ::: XP_016 ARGPAHALHPAASSSSSSSNCSRPNATASSSGLPE-------VPSALPGP---------- 50 60 70 80 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :: .:: ::. : ::: .::::. :. :: : ..::.: :::::.: ::. . ::. XP_016 --TAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLMGGRYTPPDCTPAQTVAV 90 100 110 120 130 140 190 200 210 220 230 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALK-DY :::::.:..::.:::.::::.:.::.: ::.::::: :. ::::::::::: :::: : XP_016 IIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE1 DYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT : ::.::::::.::.:.: ::: .::::...::::::: :::. ::::::.::: ::: XP_016 AYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLR 210 220 230 240 250 260 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI ::::::.::::::::::::::. . ::.::::. .:: :::.:.:::.:::::::: .: XP_016 INGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKI 270 280 290 300 310 320 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS .:: :: ::..:. ::::.:.: ::.:.:::::: : XP_016 QNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG 330 340 350 360 370 >>NP_003771 (OMIM: 604013) beta-1,4-galactosyltransferas (372 aa) initn: 1323 init1: 809 opt: 1339 Z-score: 996.7 bits: 193.2 E(87639): 9.2e-49 Smith-Waterman score: 1366; 54.0% identity (74.2% similar) in 383 aa overlap (16-397:6-365) 10 20 30 40 50 60 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLSRLPQLVGVSTPL :..:.:.:. .. .: ::. :... :. :. .:. : NP_003 MSRLLGGTLERVCKAVLLLCLLHFLVAVILYF---DV-YAQHLAFFSRFS 10 20 30 40 70 80 90 100 110 120 pF1KE1 QGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVDSGPGPASNLTSVPVP : : . ::. .. .:: ..:. :. : .. ::: NP_003 ARGPAHALHPAASSSSSSSNCSRPNATASSSGLPE-------VPSALPGP---------- 50 60 70 80 130 140 150 160 170 180 pF1KE1 HTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNVKMGGRYAPRDCVSPHKVAI :: .:: ::. : ::: .::::. :. :: : ..::.: :::::.: ::. . ::. NP_003 --TAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLMGGRYTPPDCTPAQTVAV 90 100 110 120 130 140 190 200 210 220 230 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALK-DY :::::.:..::.:::.::::.:.::.: ::.::::: :. ::::::::::: :::: : NP_003 IIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE1 DYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT : ::.::::::.::.:.: ::: .::::...::::::: :::. ::::::.::: ::: NP_003 AYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLR 210 220 230 240 250 260 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI ::::::.::::::::::::::. . ::.::::. .:: :::.:.:::.:::::::: .: NP_003 INGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKI 270 280 290 300 310 320 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS .:: :: ::..:. ::::.:.: ::.:.:::::: : NP_003 QNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG 330 340 350 360 370 >>NP_085076 (OMIM: 604013) beta-1,4-galactosyltransferas (401 aa) initn: 1323 init1: 809 opt: 1339 Z-score: 996.2 bits: 193.2 E(87639): 9.7e-49 Smith-Waterman score: 1370; 53.5% identity (73.8% similar) in 389 aa overlap (10-397:29-394) 10 20 30 40 pF1KE1 MRLREPLLSGSAAMPGASLQRACRLLVAVCALHLGVTLVYY : . . :..:.:.:. .. .: ::. :... : NP_085 MAVEVQEQWPCLPAAGCPGPLGGPVAACGMSRLLGGTLERVCKAVLLLCLLHFLVAVILY 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 LAGRDLSRLPQLVGVSTPLQGGSNSAAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSS . :. .:. : : : . ::. .. .:: ..:. :. NP_085 F---DV-YAQHLAFFSRFSARGPAHALHPAASSSSSSSNCSRPNATASSSGLPE------ 70 80 90 100 110 110 120 130 140 150 160 pF1KE1 PVVDSGPGPASNLTSVPVPHTTALSLPACPEESPLLVGPMLIEFNMPVDLELVAKQNPNV : .. ::: :: .:: ::. : ::: .::::. :. :: : ..::.: NP_085 -VPSALPGP------------TAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGV 120 130 140 150 170 180 190 200 210 220 pF1KE1 KMGGRYAPRDCVSPHKVAIIIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTI :::::.: ::. . ::.:::::.:..::.:::.::::.:.::.: ::.::::: :. NP_085 LMGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDT 160 170 180 190 200 210 230 240 250 260 270 280 pF1KE1 FNRAKLLNVGFQEALK-DYDYTCFVFSDVDLIPMNDHNAYRCFSQPRHISVAMDKFGFSL ::::::::::: :::: : : ::.::::::.::.:.: ::: .::::...::::::: : NP_085 FNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRL 220 230 240 250 260 270 290 300 310 320 330 340 pF1KE1 PYVQYFGGVSALSKQQFLTINGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRM ::. ::::::.::: ::: ::::::.::::::::::::::. . ::.::::. .:: :: NP_085 PYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRM 280 290 300 310 320 330 350 360 370 380 390 pF1KE1 IRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS :.:.:::.:::::::: .: .:: :: ::..:. ::::.:.: ::.:.:::::: : NP_085 IKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSW 340 350 360 370 380 390 NP_085 PPRG 400 >>NP_003770 (OMIM: 604014) beta-1,4-galactosyltransferas (393 aa) initn: 1124 init1: 576 opt: 1122 Z-score: 837.5 bits: 163.8 E(87639): 6.7e-40 Smith-Waterman score: 1122; 55.4% identity (77.2% similar) in 307 aa overlap (97-396:39-344) 70 80 90 100 110 120 pF1KE1 AAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVD-SGPGPA-SNLTSVP-VPH-- : :..:. : : : . :::. .: .: NP_003 PCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGP 10 20 30 40 50 60 130 140 150 160 170 180 pF1KE1 TTALSLPACPEESPLLVGPMLIEFNMPV-DLELVAKQNPNVKMGGRYAPRDCVSPHKVAI . .:: :::.:::::::. . :. :: .: ....:: :. :::: : : ..:: NP_003 PAPQGLPYCPERSPLLVGPVSVSFS-PVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAI 70 80 90 100 110 120 190 200 210 220 230 240 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD :.: : :..::. ::.::: :::::: ::::::.:::. :::::::::: .:::.: . NP_003 IVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEE 130 140 150 160 170 180 250 260 270 280 290 pF1KE1 YTCFVFSDVDLIPMNDHNAYRCFSQ-PRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT . :. . ::::.: :::: : : . :::..:::.:::.:::: :::::::::. .:.: NP_003 WDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLK 190 200 210 220 230 240 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI .:::::.::::::::::: .:. . ::.:::: . ::. .:..: :: :: ::.::: . NP_003 MNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLL 250 260 270 280 290 300 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS ..:... .::.::::::.: . ::::.::.:::: NP_003 VRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQ 310 320 330 340 350 360 NP_003 EMLQRRPPARPGPLSTANHTALRGSH 370 380 390 >>XP_005245623 (OMIM: 604014) PREDICTED: beta-1,4-galact (393 aa) initn: 1124 init1: 576 opt: 1122 Z-score: 837.5 bits: 163.8 E(87639): 6.7e-40 Smith-Waterman score: 1122; 55.4% identity (77.2% similar) in 307 aa overlap (97-396:39-344) 70 80 90 100 110 120 pF1KE1 AAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVD-SGPGPA-SNLTSVP-VPH-- : :..:. : : : . :::. .: .: XP_005 PCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGP 10 20 30 40 50 60 130 140 150 160 170 180 pF1KE1 TTALSLPACPEESPLLVGPMLIEFNMPV-DLELVAKQNPNVKMGGRYAPRDCVSPHKVAI . .:: :::.:::::::. . :. :: .: ....:: :. :::: : : ..:: XP_005 PAPQGLPYCPERSPLLVGPVSVSFS-PVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAI 70 80 90 100 110 120 190 200 210 220 230 240 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD :.: : :..::. ::.::: :::::: ::::::.:::. :::::::::: .:::.: . XP_005 IVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEE 130 140 150 160 170 180 250 260 270 280 290 pF1KE1 YTCFVFSDVDLIPMNDHNAYRCFSQ-PRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT . :. . ::::.: :::: : : . :::..:::.:::.:::: :::::::::. .:.: XP_005 WDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLK 190 200 210 220 230 240 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI .:::::.::::::::::: .:. . ::.:::: . ::. .:..: :: :: ::.::: . XP_005 MNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLL 250 260 270 280 290 300 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS ..:... .::.::::::.: . ::::.::.:::: XP_005 VRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQ 310 320 330 340 350 360 XP_005 EMLQRRPPARPGPLSTANHTALRGSH 370 380 390 >>NP_001186803 (OMIM: 604014) beta-1,4-galactosyltransfe (393 aa) initn: 1124 init1: 576 opt: 1122 Z-score: 837.5 bits: 163.8 E(87639): 6.7e-40 Smith-Waterman score: 1122; 55.4% identity (77.2% similar) in 307 aa overlap (97-396:39-344) 70 80 90 100 110 120 pF1KE1 AAAIGQSSGELRTGGARPPPPLGASSQPRPGGDSSPVVD-SGPGPA-SNLTSVP-VPH-- : :..:. : : : . :::. .: .: NP_001 PCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGP 10 20 30 40 50 60 130 140 150 160 170 180 pF1KE1 TTALSLPACPEESPLLVGPMLIEFNMPV-DLELVAKQNPNVKMGGRYAPRDCVSPHKVAI . .:: :::.:::::::. . :. :: .: ....:: :. :::: : : ..:: NP_001 PAPQGLPYCPERSPLLVGPVSVSFS-PVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAI 70 80 90 100 110 120 190 200 210 220 230 240 pF1KE1 IIPFRNRQEHLKYWLYYLHPVLQRQQLDYGIYVINQAGDTIFNRAKLLNVGFQEALKDYD :.: : :..::. ::.::: :::::: ::::::.:::. :::::::::: .:::.: . NP_001 IVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEE 130 140 150 160 170 180 250 260 270 280 290 pF1KE1 YTCFVFSDVDLIPMNDHNAYRCFSQ-PRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLT . :. . ::::.: :::: : : . :::..:::.:::.:::: :::::::::. .:.: NP_001 WDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLK 190 200 210 220 230 240 300 310 320 330 340 350 pF1KE1 INGFPNNYWGWGGEDDDIFNRLVFRGMSISRPNAVVGRCRMIRHSRDKKNEPNPQRFDRI .:::::.::::::::::: .:. . ::.:::: . ::. .:..: :: :: ::.::: . NP_001 MNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLL 250 260 270 280 290 300 360 370 380 390 pF1KE1 AHTKETMLSDGLNSLTYQVLDVQRYPLYTQITVDIGTPS ..:... .::.::::::.: . ::::.::.:::: NP_001 VRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQ 310 320 330 340 350 360 NP_001 EMLQRRPPARPGPLSTANHTALRGSH 370 380 390 398 residues in 1 query sequences 62246620 residues in 87639 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jul 27 10:34:06 2017 done: Thu Jul 27 10:34:08 2017 Total Scan time: 10.160 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]