FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1911, 445 aa 1>>>pF1KE1911 445 - 445 aa - 445 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5966+/-0.000358; mu= 16.6176+/- 0.023 mean_var=74.6496+/-14.871, 0's: 0 Z-trim(113.8): 115 B-trim: 444 in 1/53 Lambda= 0.148443 statistics sampled from 24143 (24264) to 24143 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.263), width: 16 Scan time: 4.190 The best scores are: opt bits E(92320) NP_006079 (OMIM: 602660,617879) tubulin beta-4B ch ( 445) 2992 650.2 3.3e-186 NP_006078 (OMIM: 128101,602662,612438) tubulin bet ( 444) 2944 640.0 4.1e-183 NP_001276058 (OMIM: 128101,602662,612438) tubulin ( 444) 2944 640.0 4.1e-183 NP_001276056 (OMIM: 128101,602662,612438) tubulin ( 489) 2944 640.0 4.4e-183 NP_001276052 (OMIM: 128101,602662,612438) tubulin ( 495) 2944 640.0 4.5e-183 NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 2929 636.8 3.8e-182 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 2929 636.8 3.8e-182 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 2910 632.7 6.4e-181 NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 2817 612.8 6.4e-175 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 2807 610.6 2.9e-174 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 2770 602.7 6.7e-172 NP_001290453 (OMIM: 615103,617732) tubulin beta-6 ( 446) 2754 599.3 7.3e-171 NP_115914 (OMIM: 615103,617732) tubulin beta-6 cha ( 446) 2754 599.3 7.3e-171 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 2554 556.4 5.2e-158 NP_001276060 (OMIM: 128101,602662,612438) tubulin ( 372) 2455 535.2 1.2e-151 NP_001276059 (OMIM: 128101,602662,612438) tubulin ( 372) 2455 535.2 1.2e-151 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 2448 533.7 3.3e-151 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 2448 533.7 3.3e-151 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 2434 530.8 3.1e-150 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 2375 518.1 1.7e-146 XP_011517761 (OMIM: 616768,616780) tubulin beta-8 ( 372) 2339 510.4 3.6e-144 NP_001290456 (OMIM: 615103,617732) tubulin beta-6 ( 374) 2333 509.1 8.7e-144 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 2291 500.1 4.3e-141 XP_016883574 (OMIM: 612901,613112) tubulin beta-1 ( 429) 2283 498.4 1.6e-140 NP_001290457 (OMIM: 615103,617732) tubulin beta-6 ( 381) 2194 479.3 8.1e-135 NP_001290455 (OMIM: 615103,617732) tubulin beta-6 ( 409) 2185 477.4 3.3e-134 XP_016871681 (OMIM: 616768,616780) tubulin beta-8 ( 332) 2061 450.8 2.7e-126 XP_016871682 (OMIM: 616768,616780) tubulin beta-8 ( 332) 2061 450.8 2.7e-126 NP_001290459 (OMIM: 615103,617732) tubulin beta-6 ( 300) 1840 403.4 4.4e-112 NP_001290458 (OMIM: 615103,617732) tubulin beta-6 ( 300) 1840 403.4 4.4e-112 XP_011517762 (OMIM: 616768,616780) tubulin beta-8 ( 291) 1679 369.0 1e-101 NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 1288 285.3 2.4e-76 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 1280 283.6 7.8e-76 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 1280 283.6 7.8e-76 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 1272 281.9 2.5e-75 NP_525125 (OMIM: 617878,617928) tubulin alpha-3D c ( 450) 1263 280.0 9.7e-75 NP_005992 (OMIM: 602528) tubulin alpha-3C chain [H ( 450) 1263 280.0 9.7e-75 NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 1251 277.4 5.7e-74 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 1223 271.4 3.6e-72 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 1176 261.3 3.7e-69 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 1086 242.0 2.2e-63 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 1013 226.4 1.3e-58 NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 1003 224.3 5.6e-58 XP_024306672 (OMIM: 191135,615412) tubulin gamma-1 ( 538) 847 190.9 7.4e-48 XP_024306463 (OMIM: 605785) tubulin gamma-2 chain ( 587) 846 190.7 9.2e-48 NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 834 187.9 2.6e-47 XP_016860313 (OMIM: 191110,616208) tubulin alpha-4 ( 295) 773 174.9 2.7e-43 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 624 143.1 1.5e-33 NP_001290454 (OMIM: 615103,617732) tubulin beta-6 ( 104) 563 129.7 3.9e-30 XP_024306467 (OMIM: 605785) tubulin gamma-2 chain ( 357) 530 122.9 1.4e-27 >>NP_006079 (OMIM: 602660,617879) tubulin beta-4B chain (445 aa) initn: 2992 init1: 2992 opt: 2992 Z-score: 3464.6 bits: 650.2 E(92320): 3.3e-186 Smith-Waterman score: 2992; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA ::::::::::::::::::::::::: NP_006 EYQQYQDATAEEEGEFEEEAEEEVA 430 440 >>NP_006078 (OMIM: 128101,602662,612438) tubulin beta-4A (444 aa) initn: 2893 init1: 2893 opt: 2944 Z-score: 3409.1 bits: 640.0 E(92320): 4.1e-183 Smith-Waterman score: 2944; 98.4% identity (99.8% similar) in 445 aa overlap (1-445:1-444) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::.::.::::::::::::::::::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA :::::::::::: :::::::::::: NP_006 EYQQYQDATAEE-GEFEEEAEEEVA 430 440 >>NP_001276058 (OMIM: 128101,602662,612438) tubulin beta (444 aa) initn: 2893 init1: 2893 opt: 2944 Z-score: 3409.1 bits: 640.0 E(92320): 4.1e-183 Smith-Waterman score: 2944; 98.4% identity (99.8% similar) in 445 aa overlap (1-445:1-444) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: NP_001 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_001 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::.::.::::::::::::::::::::::::: NP_001 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA :::::::::::: :::::::::::: NP_001 EYQQYQDATAEE-GEFEEEAEEEVA 430 440 >>NP_001276056 (OMIM: 128101,602662,612438) tubulin beta (489 aa) initn: 2893 init1: 2893 opt: 2944 Z-score: 3408.5 bits: 640.0 E(92320): 4.4e-183 Smith-Waterman score: 2944; 98.4% identity (99.8% similar) in 445 aa overlap (1-445:46-489) 10 20 30 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGI :::::::::::::::::::::::::::::: NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE1 DPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE1 VFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL 140 150 160 170 180 190 160 170 180 190 200 210 pF1KE1 LISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 200 210 220 230 240 250 220 230 240 250 260 270 pF1KE1 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF 260 270 280 290 300 310 280 290 300 310 320 330 pF1KE1 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 320 330 340 350 360 370 340 350 360 370 380 390 pF1KE1 LNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFR :.::.::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 380 390 400 410 420 430 400 410 420 430 440 pF1KE1 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA :::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE-GEFEEEAEEEVA 440 450 460 470 480 >>NP_001276052 (OMIM: 128101,602662,612438) tubulin beta (495 aa) initn: 2893 init1: 2893 opt: 2944 Z-score: 3408.4 bits: 640.0 E(92320): 4.5e-183 Smith-Waterman score: 2944; 98.4% identity (99.8% similar) in 445 aa overlap (1-445:52-495) 10 20 30 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGI :::::::::::::::::::::::::::::: NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KE1 DPTGTYHGDSDLQLERINVYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF 90 100 110 120 130 140 100 110 120 130 140 150 pF1KE1 VFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KE1 LISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 210 220 230 240 250 260 220 230 240 250 260 270 pF1KE1 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF 270 280 290 300 310 320 280 290 300 310 320 330 pF1KE1 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 330 340 350 360 370 380 340 350 360 370 380 390 pF1KE1 LNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFR :.::.::::::::::::::::::::::::::::.:::::::::::::::::::::::::: NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 390 400 410 420 430 440 400 410 420 430 440 pF1KE1 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA :::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE-GEFEEEAEEEVA 450 460 470 480 490 >>NP_821133 (OMIM: 156610,191130,615771) tubulin beta ch (444 aa) initn: 2929 init1: 2929 opt: 2929 Z-score: 3391.7 bits: 636.8 E(92320): 3.8e-182 Smith-Waterman score: 2929; 97.7% identity (99.5% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::::::::::::.::.:::::::::::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA ::::::::::::: .: :::::: NP_821 EYQQYQDATAEEEEDFGEEAEEEA 430 440 >>NP_821080 (OMIM: 610031,612850) tubulin beta-2B chain (445 aa) initn: 2929 init1: 2929 opt: 2929 Z-score: 3391.7 bits: 636.8 E(92320): 3.8e-182 Smith-Waterman score: 2929; 96.9% identity (99.3% similar) in 445 aa overlap (1-445:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::.:::::::::::::::::::::.::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_821 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_821 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA ::::::::::.:.:::::: :. : NP_821 EYQQYQDATADEQGEFEEEEGEDEA 430 440 >>NP_001060 (OMIM: 615101,615763) tubulin beta-2A chain (445 aa) initn: 2910 init1: 2910 opt: 2910 Z-score: 3369.7 bits: 632.7 E(92320): 6.4e-181 Smith-Waterman score: 2910; 96.4% identity (99.1% similar) in 445 aa overlap (1-445:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::.:::::::::::::::::::.:.::: NP_001 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_001 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_001 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_001 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA ::::::::::.:.:::::: :. : NP_001 EYQQYQDATADEQGEFEEEEGEDEA 430 440 >>NP_006077 (OMIM: 600638,602661,614039) tubulin beta-3 (450 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 3262.0 bits: 612.8 E(92320): 6.4e-175 Smith-Waterman score: 2817; 93.2% identity (98.2% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. ::: NP_006 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_006 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_006 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: NP_006 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KE1 EYQQYQDATAEEEGEFEEEAEEEVA :::::::::::::::. :. ::: NP_006 EYQQYQDATAEEEGEMYEDDEEESEAQGPK 430 440 450 >>NP_001280141 (OMIM: 156610,191130,615771) tubulin beta (464 aa) initn: 2807 init1: 2807 opt: 2807 Z-score: 3250.3 bits: 610.6 E(92320): 2.9e-174 Smith-Waterman score: 2807; 97.9% identity (99.5% similar) in 425 aa overlap (19-443:39-463) 10 20 30 40 pF1KE1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERIN ::::::::::::::::::::::::::.::. NP_001 ANWDPSRSGVRDHPGQQSETLPHATFLQKIKFWEVISDEHGIDPTGTYHGDSDLQLDRIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KE1 VYYNEATGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTE :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_001 VYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE1 GAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE1 VVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE1 VSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPE 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE1 LTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNN ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE1 VKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF :::::::::::::::..::::::::::::::::::::::::::::::::::::::::::: NP_001 VKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF 370 380 390 400 410 420 410 420 430 440 pF1KE1 TEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEEVA ::::::::::::::::::::::::: .: :::::: NP_001 TEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA 430 440 450 460 445 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:44:04 2019 done: Thu Oct 24 21:44:04 2019 Total Scan time: 4.190 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]