FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1913, 450 aa 1>>>pF1KE1913 450 - 450 aa - 450 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5629+/-0.000914; mu= 16.5937+/- 0.055 mean_var=73.4691+/-14.669, 0's: 0 Z-trim(106.4): 38 B-trim: 257 in 2/50 Lambda= 0.149631 statistics sampled from 9029 (9067) to 9029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.271), width: 16 Scan time: 1.430 The best scores are: opt bits E(33420) CCDS10988.1 TUBB3 gene_id:10381|Hs109|chr16 ( 450) 3025 662.4 2.6e-190 CCDS7039.1 TUBB4B gene_id:10383|Hs109|chr9 ( 445) 2817 617.5 8.5e-177 CCDS11858.1 TUBB6 gene_id:84617|Hs109|chr18 ( 446) 2810 616.0 2.4e-176 CCDS4485.1 TUBB2B gene_id:347733|Hs109|chr6 ( 445) 2808 615.6 3.3e-176 CCDS4687.1 TUBB gene_id:203068|Hs109|chr6 ( 444) 2793 612.4 3.1e-175 CCDS4484.1 TUBB2A gene_id:7280|Hs109|chr6 ( 445) 2793 612.4 3.1e-175 CCDS12168.1 TUBB4A gene_id:10382|Hs109|chr19 ( 444) 2787 611.1 7.6e-175 CCDS7051.1 TUBB8 gene_id:347688|Hs109|chr10 ( 444) 2634 578.0 6.6e-165 CCDS86657.1 TUBB8P12 gene_id:260334|Hs109|chr18 ( 444) 2559 561.8 5e-160 CCDS56012.1 TUBB3 gene_id:10381|Hs109|chr16 ( 378) 2536 556.8 1.4e-158 CCDS13475.1 TUBB1 gene_id:81027|Hs109|chr20 ( 451) 2437 535.5 4.3e-152 CCDS78124.1 TUBB gene_id:203068|Hs109|chr6 ( 372) 2347 516.0 2.6e-146 CCDS31792.1 TUBA1B gene_id:10376|Hs109|chr12 ( 451) 1273 284.2 1.9e-76 CCDS58227.1 TUBA1A gene_id:7846|Hs109|chr12 ( 451) 1265 282.5 6.2e-76 CCDS8781.1 TUBA1A gene_id:7846|Hs109|chr12 ( 451) 1265 282.5 6.2e-76 CCDS8782.1 TUBA1C gene_id:84790|Hs109|chr12 ( 449) 1262 281.9 9.6e-76 CCDS2438.1 TUBA4A gene_id:7277|Hs109|chr2 ( 448) 1261 281.6 1.1e-75 CCDS76556.1 TUBA1C gene_id:84790|Hs109|chr12 ( 519) 1255 280.4 3.1e-75 CCDS9284.1 TUBA3C gene_id:7278|Hs109|chr13 ( 450) 1248 278.8 7.8e-75 CCDS33290.1 TUBA3D gene_id:113457|Hs109|chr2 ( 450) 1248 278.8 7.8e-75 CCDS13751.1 TUBA8 gene_id:51807|Hs109|chr22 ( 449) 1239 276.9 3e-74 CCDS2158.1 TUBA3E gene_id:112714|Hs109|chr2 ( 450) 1222 273.2 3.8e-73 CCDS63131.1 TUBA4A gene_id:7277|Hs109|chr2 ( 433) 1209 270.4 2.6e-72 CCDS58226.1 TUBA1A gene_id:7846|Hs109|chr12 ( 416) 1169 261.8 1e-69 CCDS54495.1 TUBA8 gene_id:51807|Hs109|chr22 ( 383) 1087 244.0 2e-64 CCDS53491.1 TUBAL3 gene_id:79861|Hs109|chr10 ( 406) 1075 241.5 1.3e-63 CCDS7066.2 TUBAL3 gene_id:79861|Hs109|chr10 ( 446) 1075 241.5 1.4e-63 CCDS11433.1 TUBG1 gene_id:7283|Hs109|chr17 ( 451) 997 224.6 1.6e-58 CCDS32658.1 TUBG2 gene_id:27175|Hs109|chr17 ( 451) 987 222.5 7.2e-58 CCDS77153.1 TUBB6 gene_id:84617|Hs109|chr18 ( 104) 569 131.9 3.1e-31 CCDS86922.1 TUBA4B gene_id:80086|Hs109|chr2 ( 241) 545 126.9 2.2e-29 CCDS5100.1 TUBE1 gene_id:51175|Hs109|chr6 ( 475) 500 117.4 3.3e-26 CCDS54154.1 TUBD1 gene_id:51174|Hs109|chr17 ( 396) 450 106.5 5.1e-23 CCDS11620.1 TUBD1 gene_id:51174|Hs109|chr17 ( 453) 450 106.6 5.7e-23 CCDS54152.1 TUBD1 gene_id:51174|Hs109|chr17 ( 351) 428 101.8 1.2e-21 CCDS54153.1 TUBD1 gene_id:51174|Hs109|chr17 ( 398) 428 101.8 1.4e-21 >>CCDS10988.1 TUBB3 gene_id:10381|Hs109|chr16 (450 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 3530.3 bits: 662.4 E(33420): 2.6e-190 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::::::::::::::::: CCDS10 EYQQYQDATAEEEGEMYEDDEEESEAQGPK 430 440 450 >>CCDS7039.1 TUBB4B gene_id:10383|Hs109|chr9 (445 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 3287.7 bits: 617.5 E(33420): 8.5e-177 Smith-Waterman score: 2817; 93.2% identity (98.2% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. ::: CCDS70 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: CCDS70 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS70 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : CCDS70 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS70 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: CCDS70 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::. :. ::: CCDS70 EYQQYQDATAEEEGEFEEEAEEEVA 430 440 >>CCDS11858.1 TUBB6 gene_id:84617|Hs109|chr18 (446 aa) initn: 2810 init1: 2810 opt: 2810 Z-score: 3279.6 bits: 616.0 E(33420): 2.4e-176 Smith-Waterman score: 2810; 93.0% identity (98.4% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV :::::::::::::::::.::::::::::::::.:.::::: ::::::.:::::.::.::: CCDS11 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::: ::::::::::::::: ::.:::::::::::.:::::::::::::::::::.::::: CCDS11 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV :::::.::::::::::::::::::::::::::::.:::.::::::::::.:::::::::: CCDS11 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS11 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::.::: CCDS11 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS11 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::.:::::::::::::::::::::.:::::::::::.:::::::::::::::::::::: CCDS11 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.. : .::.::: CCDS11 EYQQYQDATANDGEEAFEDEEEEIDG 430 440 >>CCDS4485.1 TUBB2B gene_id:347733|Hs109|chr6 (445 aa) initn: 2799 init1: 2799 opt: 2808 Z-score: 3277.2 bits: 615.6 E(33420): 3.3e-176 Smith-Waterman score: 2808; 92.2% identity (98.4% similar) in 446 aa overlap (1-446:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: ::::::::::.::::::...::: CCDS44 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: CCDS44 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::.:::::::::: CCDS44 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : CCDS44 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::.:::: CCDS44 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::..::::::::::::::: .:.:::::::::::::::.::::::::: CCDS44 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.:.:: .:..: :.:: CCDS44 EYQQYQDATADEQGE-FEEEEGEDEA 430 440 >>CCDS4687.1 TUBB gene_id:203068|Hs109|chr6 (444 aa) initn: 2793 init1: 2793 opt: 2793 Z-score: 3259.8 bits: 612.4 E(33420): 3.1e-175 Smith-Waterman score: 2793; 92.6% identity (97.7% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: :::::::.:::::::::.. ::: CCDS46 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: CCDS46 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS46 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : CCDS46 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::.::::::: CCDS46 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: CCDS46 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::. ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::::: .. :. :::. CCDS46 EYQQYQDATAEEEEDFGEEAEEEA 430 440 >>CCDS4484.1 TUBB2A gene_id:7280|Hs109|chr6 (445 aa) initn: 2784 init1: 2784 opt: 2793 Z-score: 3259.7 bits: 612.4 E(33420): 3.1e-175 Smith-Waterman score: 2793; 91.9% identity (98.2% similar) in 446 aa overlap (1-446:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: ::::::::::.::::::...::: CCDS44 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: CCDS44 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::.:::::::::: CCDS44 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::: ::::::::::::::::.:::::::::::::::::::: : CCDS44 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::.:::: CCDS44 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::..::::::::::::::: .:.:::::::::::::::.::::::::: CCDS44 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.:.:: .:..: :.:: CCDS44 EYQQYQDATADEQGE-FEEEEGEDEA 430 440 >>CCDS12168.1 TUBB4A gene_id:10382|Hs109|chr19 (444 aa) initn: 2768 init1: 2768 opt: 2787 Z-score: 3252.8 bits: 611.1 E(33420): 7.6e-175 Smith-Waterman score: 2787; 92.3% identity (98.2% similar) in 443 aa overlap (1-443:1-442) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. .:: CCDS12 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.:::::::::::::::::::::::.::::: CCDS12 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.:::.::::::::::::::::::::: CCDS12 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : CCDS12 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: CCDS12 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.::::::::::::::::..:::::::::::::::::.::::::::: CCDS12 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::: ::. :. ::: CCDS12 EYQQYQDATAEE-GEFEEEAEEEVA 430 440 >>CCDS7051.1 TUBB8 gene_id:347688|Hs109|chr10 (444 aa) initn: 2631 init1: 2631 opt: 2634 Z-score: 3074.3 bits: 578.0 E(33420): 6.6e-165 Smith-Waterman score: 2634; 86.7% identity (95.5% similar) in 442 aa overlap (1-441:1-442) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::: : :::::::::::::::::::.:: .:.: ::: ::::::.:::::::. .:: CCDS70 MREIVLTQIGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVYYNEASGGRYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..:::::::::: :::::::::::::::::..::.::: CCDS70 PRAVLVDLEPGTMDSVRSGPFGQVFRPDNFIFGQCGAGNNWAKGHYTEGAELMESVMDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.:::::::::::::::::::::::::.::.::::::::.::::..:::::::::: CCDS70 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLLSKIREEYPDRIINTFSILPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.:::.::.:::.::::::::::: .:::: :::::::::::::::::::: : CCDS70 EPYNATLSVHQLIENADETFCIDNEALYDICSKTLKLPTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::: ::::::::::::: CCDS70 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::.:..::::: :.::::::. ::.::::::..:.:::::.::::::::: CCDS70 AACDPRHGRYLTAAAIFRGRMPMREVDEQMFNIQDKNSSYFADWLPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.:::::.:::::::::.::::::::::::::::::::::::::::::::::::::: CCDS70 LKMSATFIGNNTAIQELFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEE-GEMYEDDEEESEAQGPK ::::::::::::: : : ..: CCDS70 EYQQYQDATAEEEEDEEYAEEEVA 430 440 >>CCDS86657.1 TUBB8P12 gene_id:260334|Hs109|chr18 (444 aa) initn: 2556 init1: 2556 opt: 2559 Z-score: 2986.8 bits: 561.8 E(33420): 5e-160 Smith-Waterman score: 2559; 84.8% identity (94.8% similar) in 442 aa overlap (1-441:1-442) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::: :.:::::::::::::::::::.:: .:.: ::: ::::::.:...:::. .:: CCDS86 MREIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::.:: ::..::::::: :: :::::::::.:::::::..::.::: CCDS86 PRAVLVDLEPGTMDSVHSGPFGQVFRPDNFISGQCGAGNNWAKGRYTEGAELTESVMDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::.::::..:::::::::: CCDS86 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.:::.::.:::.::::::::::: ::::: :::::::::::::::::::: : CCDS86 EPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::: ::::::::::::: CCDS86 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG :::::::: :::::..::::: :.::::::. ::.::::::..:.:.:::.::::::::: CCDS86 AACDPRHGCYLTVAAIFRGRMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.:::::..:::::: .::::::::::::::::::::::::::::::::::::::: CCDS86 LKMSATFIGNNAAIQELFTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEE-GEMYEDDEEESEAQGPK ::::::::::::: : : ..: CCDS86 EYQQYQDATAEEEEDEEYAEEEVA 430 440 >>CCDS56012.1 TUBB3 gene_id:10381|Hs109|chr16 (378 aa) initn: 2536 init1: 2536 opt: 2536 Z-score: 2961.0 bits: 556.8 E(33420): 1.4e-158 Smith-Waterman score: 2536; 100.0% identity (100.0% similar) in 378 aa overlap (73-450:1-378) 50 60 70 80 90 100 pF1KE1 QLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWA :::::::::::::::::::::::::::::: CCDS56 MDSVRSGAFGHLFRPDNFIFGQSGAGNNWA 10 20 30 110 120 130 140 150 160 pF1KE1 KGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 KGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDR 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE1 IMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 IMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTY 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE1 GDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 GDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYR 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE1 ALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 ALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KE1 EWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 EWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEG 280 290 300 310 320 330 410 420 430 440 450 pF1KE1 MDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK 340 350 360 370 450 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 16:05:24 2019 done: Tue Jul 16 16:05:24 2019 Total Scan time: 1.430 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]