FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1913, 450 aa 1>>>pF1KE1913 450 - 450 aa - 450 aa Library: /omim/omim.rfq.tfa 64092750 residues in 91774 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5917+/-0.000367; mu= 16.4584+/- 0.023 mean_var=77.7414+/-15.377, 0's: 0 Z-trim(113.6): 113 B-trim: 374 in 2/53 Lambda= 0.145462 statistics sampled from 23698 (23819) to 23698 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.26), width: 16 Scan time: 4.230 The best scores are: opt bits E(91774) NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 3025 644.6 1.7e-184 NP_006079 (OMIM: 602660,617879) tubulin beta-4B ch ( 445) 2817 600.9 2.3e-171 NP_115914 (OMIM: 615103,617732) tubulin beta-6 cha ( 446) 2810 599.5 6.4e-171 NP_001290453 (OMIM: 615103,617732) tubulin beta-6 ( 446) 2810 599.5 6.4e-171 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 2808 599.1 8.5e-171 NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 2793 595.9 7.5e-170 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 2793 595.9 7.5e-170 NP_006078 (OMIM: 128101,602662,612438) tubulin bet ( 444) 2787 594.7 1.8e-169 NP_001276058 (OMIM: 128101,602662,612438) tubulin ( 444) 2787 594.7 1.8e-169 NP_001276056 (OMIM: 128101,602662,612438) tubulin ( 489) 2787 594.7 1.9e-169 NP_001276052 (OMIM: 128101,602662,612438) tubulin ( 495) 2787 594.7 2e-169 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 2668 569.7 6.2e-162 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 2634 562.5 8.3e-160 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 2536 541.9 1.1e-153 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 2447 523.3 5e-148 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 2437 521.2 2.4e-147 NP_001290456 (OMIM: 615103,617732) tubulin beta-6 ( 374) 2370 507.1 3.5e-143 NP_001276059 (OMIM: 128101,602662,612438) tubulin ( 372) 2351 503.1 5.5e-142 NP_001276060 (OMIM: 128101,602662,612438) tubulin ( 372) 2351 503.1 5.5e-142 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 2347 502.3 9.8e-142 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 2347 502.3 9.8e-142 XP_016883574 (OMIM: 612901,613112) tubulin beta-1 ( 429) 2283 488.9 1.2e-137 NP_001290457 (OMIM: 615103,617732) tubulin beta-6 ( 381) 2245 480.9 2.8e-135 XP_011517761 (OMIM: 616768,616780) tubulin beta-8 ( 372) 2243 480.4 3.6e-135 NP_001290455 (OMIM: 615103,617732) tubulin beta-6 ( 409) 2235 478.8 1.3e-134 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 2221 475.8 8.7e-134 XP_016871682 (OMIM: 616768,616780) tubulin beta-8 ( 332) 1984 426.1 7.6e-119 XP_016871681 (OMIM: 616768,616780) tubulin beta-8 ( 332) 1984 426.1 7.6e-119 NP_001290459 (OMIM: 615103,617732) tubulin beta-6 ( 300) 1874 402.9 6.2e-112 NP_001290458 (OMIM: 615103,617732) tubulin beta-6 ( 300) 1874 402.9 6.2e-112 XP_011517762 (OMIM: 616768,616780) tubulin beta-8 ( 291) 1614 348.4 1.6e-95 NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 1273 276.9 8e-74 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 1265 275.3 2.6e-73 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 1265 275.3 2.6e-73 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 1261 274.4 4.6e-73 NP_005992 (OMIM: 602528) tubulin alpha-3C chain [H ( 450) 1248 271.7 3e-72 NP_525125 (OMIM: 617878,617928) tubulin alpha-3D c ( 450) 1248 271.7 3e-72 NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 1239 269.8 1.1e-71 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 1209 263.5 8.6e-70 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 1169 255.1 2.8e-67 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 1087 237.9 4e-62 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 997 219.0 2.2e-56 NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 987 216.9 9.4e-56 XP_024306672 (OMIM: 191135,615412) tubulin gamma-1 ( 538) 826 183.2 1.6e-45 XP_024306463 (OMIM: 605785) tubulin gamma-2 chain ( 587) 825 183.0 2e-45 XP_016860313 (OMIM: 191110,616208) tubulin alpha-4 ( 295) 779 173.1 9.2e-43 NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 777 172.7 1e-42 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 629 141.8 3.9e-33 NP_001290454 (OMIM: 615103,617732) tubulin beta-6 ( 104) 569 128.8 7.3e-30 XP_024306467 (OMIM: 605785) tubulin gamma-2 chain ( 357) 536 122.2 2.4e-27 >>NP_006077 (OMIM: 600638,602661,614039) tubulin beta-3 (450 aa) initn: 3025 init1: 3025 opt: 3025 Z-score: 3433.9 bits: 644.6 E(91774): 1.7e-184 Smith-Waterman score: 3025; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::::::::::::::::: NP_006 EYQQYQDATAEEEGEMYEDDEEESEAQGPK 430 440 450 >>NP_006079 (OMIM: 602660,617879) tubulin beta-4B chain (445 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 3198.1 bits: 600.9 E(91774): 2.3e-171 Smith-Waterman score: 2817; 93.2% identity (98.2% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. ::: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::. :. ::: NP_006 EYQQYQDATAEEEGEFEEEAEEEVA 430 440 >>NP_115914 (OMIM: 615103,617732) tubulin beta-6 chain i (446 aa) initn: 2810 init1: 2810 opt: 2810 Z-score: 3190.1 bits: 599.5 E(91774): 6.4e-171 Smith-Waterman score: 2810; 93.0% identity (98.4% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV :::::::::::::::::.::::::::::::::.:.::::: ::::::.:::::.::.::: NP_115 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::: ::::::::::::::: ::.:::::::::::.:::::::::::::::::::.::::: NP_115 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV :::::.::::::::::::::::::::::::::::.:::.::::::::::.:::::::::: NP_115 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_115 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::.::: NP_115 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_115 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::.:::::::::::::::::::::.:::::::::::.:::::::::::::::::::::: NP_115 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.. : .::.::: NP_115 EYQQYQDATANDGEEAFEDEEEEIDG 430 440 >>NP_001290453 (OMIM: 615103,617732) tubulin beta-6 chai (446 aa) initn: 2810 init1: 2810 opt: 2810 Z-score: 3190.1 bits: 599.5 E(91774): 6.4e-171 Smith-Waterman score: 2810; 93.0% identity (98.4% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV :::::::::::::::::.::::::::::::::.:.::::: ::::::.:::::.::.::: NP_001 MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::: ::::::::::::::: ::.:::::::::::.:::::::::::::::::::.::::: NP_001 PRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV :::::.::::::::::::::::::::::::::::.:::.::::::::::.:::::::::: NP_001 RKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::::: NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::::::.::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: NP_001 AACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::.:::::::::::::::::::::.:::::::::::.:::::::::::::::::::::: NP_001 LKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.. : .::.::: NP_001 EYQQYQDATANDGEEAFEDEEEEIDG 430 440 >>NP_821080 (OMIM: 610031,612850) tubulin beta-2B chain (445 aa) initn: 2799 init1: 2799 opt: 2808 Z-score: 3187.9 bits: 599.1 E(91774): 8.5e-171 Smith-Waterman score: 2808; 92.2% identity (98.4% similar) in 446 aa overlap (1-446:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: ::::::::::.::::::...::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::.:::::::::: NP_821 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::.:::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::..::::::::::::::: .:.:::::::::::::::.::::::::: NP_821 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.:.:: .:..: :.:: NP_821 EYQQYQDATADEQGE-FEEEEGEDEA 430 440 >>NP_821133 (OMIM: 156610,191130,615771) tubulin beta ch (444 aa) initn: 2793 init1: 2793 opt: 2793 Z-score: 3170.9 bits: 595.9 E(91774): 7.5e-170 Smith-Waterman score: 2793; 92.6% identity (97.7% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: :::::::.:::::::::.. ::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_821 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::.::::::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: NP_821 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::. ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::::: .. :. :::. NP_821 EYQQYQDATAEEEEDFGEEAEEEA 430 440 >>NP_001060 (OMIM: 615101,615763) tubulin beta-2A chain (445 aa) initn: 2784 init1: 2784 opt: 2793 Z-score: 3170.9 bits: 595.9 E(91774): 7.5e-170 Smith-Waterman score: 2793; 91.9% identity (98.2% similar) in 446 aa overlap (1-446:1-445) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::::::::::::::::::::::::::::.:.: ::::::::::.::::::...::: NP_001 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_001 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::.:::::::::: NP_001 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::: ::::::::::::::::.:::::::::::::::::::: : NP_001 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::.:::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::..::::::::::::::: .:.:::::::::::::::.::::::::: NP_001 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK ::::::::::.:.:: .:..: :.:: NP_001 EYQQYQDATADEQGE-FEEEEGEDEA 430 440 >>NP_006078 (OMIM: 128101,602662,612438) tubulin beta-4A (444 aa) initn: 2768 init1: 2768 opt: 2787 Z-score: 3164.1 bits: 594.7 E(91774): 1.8e-169 Smith-Waterman score: 2787; 92.3% identity (98.2% similar) in 443 aa overlap (1-443:1-442) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. .:: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.:::::::::::::::::::::::.::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.:::.::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.::::::::::::::::..:::::::::::::::::.::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::: ::. :. ::: NP_006 EYQQYQDATAEE-GEFEEEAEEEVA 430 440 >>NP_001276058 (OMIM: 128101,602662,612438) tubulin beta (444 aa) initn: 2768 init1: 2768 opt: 2787 Z-score: 3164.1 bits: 594.7 E(91774): 1.8e-169 Smith-Waterman score: 2787; 92.3% identity (98.2% similar) in 443 aa overlap (1-443:1-442) 10 20 30 40 50 60 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV ::::::.:::::::::::::::::::::::::.:.: ::::::::::.::::::.. .:: NP_001 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::: ::..::::::.:::::::::::::::::::::::.::::: NP_001 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.:::.::::::::::::::::::::: NP_001 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM ::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG ::::::::::::::.::::::::::::::::..:::::::::::::::::.::::::::: NP_001 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 450 pF1KE1 EYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::: ::. :. ::: NP_001 EYQQYQDATAEE-GEFEEEAEEEVA 430 440 >>NP_001276056 (OMIM: 128101,602662,612438) tubulin beta (489 aa) initn: 2768 init1: 2768 opt: 2787 Z-score: 3163.5 bits: 594.7 E(91774): 1.9e-169 Smith-Waterman score: 2787; 92.3% identity (98.2% similar) in 443 aa overlap (1-443:46-487) 10 20 30 pF1KE1 MREIVHIQAGQCGNQIGAKFWEVISDEHGI ::::::.::::::::::::::::::::::: NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI 20 30 40 50 60 70 40 50 60 70 80 90 pF1KE1 DPSGNYVGDSDLQLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNF ::.:.: ::::::::::.::::::.. .:::::.::::::::::::::: ::..:::::: NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF 80 90 100 110 120 130 100 110 120 130 140 150 pF1KE1 IFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTL .:::::::::::::::::::::::.:::::::: :.:::::::::::::::::::::::: NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL 140 150 160 170 180 190 160 170 180 190 200 210 pF1KE1 LISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDI ::::.:::.:::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 200 210 220 230 240 250 220 230 240 250 260 270 pF1KE1 CFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF :::::::.:::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF 260 270 280 290 300 310 280 290 300 310 320 330 pF1KE1 APLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQM ::::.:::::::::::::::::::::::::::::::::::::::.::::::::::::::: NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 320 330 340 350 360 370 340 350 360 370 380 390 pF1KE1 LAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFR :..:::::::::::::::::.::::::::::::..::::::::::::::::::::::::: NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 380 390 400 410 420 430 400 410 420 430 440 450 pF1KE1 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK :::::::::::::::::::::::::::::::::::::::::: ::. :. ::: NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEE-GEFEEEAEEEVA 440 450 460 470 480 450 residues in 1 query sequences 64092750 residues in 91774 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 16:05:24 2019 done: Tue Jul 16 16:05:25 2019 Total Scan time: 4.230 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]