FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE1993, 572 aa 1>>>pF1KE1993 572 - 572 aa - 572 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8988+/-0.00035; mu= 16.1918+/- 0.022 mean_var=74.7541+/-14.820, 0's: 0 Z-trim(115.1): 29 B-trim: 477 in 1/51 Lambda= 0.148339 statistics sampled from 26314 (26343) to 26314 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.285), width: 16 Scan time: 4.920 The best scores are: opt bits E(92320) NP_001377 (OMIM: 602463) dihydropyrimidinase-relat ( 572) 3795 821.6 0 NP_001184222 (OMIM: 602463) dihydropyrimidinase-re ( 677) 3714 804.3 0 NP_001231533 (OMIM: 602463) dihydropyrimidinase-re ( 536) 3559 771.1 0 NP_001304 (OMIM: 602462) dihydropyrimidinase-relat ( 572) 3063 665.0 2e-190 NP_001378 (OMIM: 601168) dihydropyrimidinase-relat ( 570) 3062 664.8 2.3e-190 NP_006417 (OMIM: 608407) dihydropyrimidinase-relat ( 572) 3015 654.7 2.5e-187 NP_001275591 (OMIM: 602462) dihydropyrimidinase-re ( 566) 2990 649.4 9.9e-186 NP_001275590 (OMIM: 602462) dihydropyrimidinase-re ( 570) 2990 649.4 1e-185 NP_001014809 (OMIM: 602462) dihydropyrimidinase-re ( 686) 2990 649.4 1.2e-185 NP_001184223 (OMIM: 601168) dihydropyrimidinase-re ( 684) 2984 648.1 2.9e-185 XP_011535876 (OMIM: 601168) dihydropyrimidinase-re ( 566) 2977 646.6 6.8e-185 XP_016870972 (OMIM: 608407) dihydropyrimidinase-re ( 509) 2655 577.7 3.5e-164 XP_005252715 (OMIM: 608407) dihydropyrimidinase-re ( 509) 2655 577.7 3.5e-164 XP_016870971 (OMIM: 608407) dihydropyrimidinase-re ( 509) 2655 577.7 3.5e-164 XP_011537427 (OMIM: 608407) dihydropyrimidinase-re ( 509) 2655 577.7 3.5e-164 NP_001376 (OMIM: 222748,613326) dihydropyrimidinas ( 519) 2123 463.8 6.6e-130 XP_024308775 (OMIM: 608383) dihydropyrimidinase-re ( 564) 1967 430.4 8e-120 NP_001240652 (OMIM: 608383) dihydropyrimidinase-re ( 564) 1967 430.4 8e-120 NP_001240653 (OMIM: 608383) dihydropyrimidinase-re ( 564) 1967 430.4 8e-120 NP_064519 (OMIM: 608383) dihydropyrimidinase-relat ( 564) 1967 430.4 8e-120 XP_016868656 (OMIM: 222748,613326) dihydropyrimidi ( 454) 1794 393.4 9.2e-109 XP_011515205 (OMIM: 222748,613326) dihydropyrimidi ( 517) 1794 393.4 1e-108 XP_024302855 (OMIM: 222748,613326) dihydropyrimidi ( 555) 1794 393.4 1.1e-108 XP_005250875 (OMIM: 222748,613326) dihydropyrimidi ( 555) 1794 393.4 1.1e-108 XP_006716581 (OMIM: 222748,613326) dihydropyrimidi ( 502) 1274 282.1 3.2e-75 XP_024308899 (OMIM: 114010,616457) CAD protein iso (1484) 157 43.3 0.0075 >>NP_001377 (OMIM: 602463) dihydropyrimidinase-related p (572 aa) initn: 3795 init1: 3795 opt: 3795 Z-score: 4387.0 bits: 821.6 E(92320): 0 Smith-Waterman score: 3795; 100.0% identity (100.0% similar) in 572 aa overlap (1-572:1-572) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS 490 500 510 520 530 540 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG :::::::::::::::::::::::::::::::: NP_001 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG 550 560 570 >>NP_001184222 (OMIM: 602463) dihydropyrimidinase-relate (677 aa) initn: 3709 init1: 3709 opt: 3714 Z-score: 4292.2 bits: 804.3 E(92320): 0 Smith-Waterman score: 3714; 98.6% identity (99.1% similar) in 570 aa overlap (5-572:108-677) 10 20 30 pF1KE1 MSYQGKKNIPRIT--SDRLLIKGGKIVNDDQSFY ::. . :. ::::::::::::::::::: NP_001 PQPPYSRQGRRAGGEPSVESGRKVEIRRASGKEALQNINDQSDRLLIKGGKIVNDDQSFY 80 90 100 110 120 130 40 50 60 70 80 90 pF1KE1 ADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQG 140 150 160 170 180 190 100 110 120 130 140 150 pF1KE1 TKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEM 200 210 220 230 240 250 160 170 180 190 200 210 pF1KE1 EALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRI 260 270 280 290 300 310 220 230 240 250 260 270 pF1KE1 LDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGT 320 330 340 350 360 370 280 290 300 310 320 330 pF1KE1 VVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSA 380 390 400 410 420 430 340 350 360 370 380 390 pF1KE1 HCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVF 440 450 460 470 480 490 400 410 420 430 440 450 pF1KE1 NLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKI 500 510 520 530 540 550 460 470 480 490 500 510 pF1KE1 VLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKT 560 570 580 590 600 610 520 530 540 550 560 570 pF1KE1 VTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG 620 630 640 650 660 670 >>NP_001231533 (OMIM: 602463) dihydropyrimidinase-relate (536 aa) initn: 3559 init1: 3559 opt: 3559 Z-score: 4114.5 bits: 771.1 E(92320): 0 Smith-Waterman score: 3559; 100.0% identity (100.0% similar) in 536 aa overlap (37-572:1-536) 10 20 30 40 50 60 pF1KE1 KNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVI :::::::::::::::::::::::::::::: NP_001 MEDGLIKQIGENLIVPGGVKTIEAHSRMVI 10 20 30 70 80 90 100 110 120 pF1KE1 PGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREW 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE1 ADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE1 VIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQT 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE1 NCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPP 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE1 LSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIW 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE1 DKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE1 SSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARS 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE1 RLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQI 460 470 480 490 500 510 550 560 570 pF1KE1 DDNIPRRTTQRIVAPPGGRANITSLG :::::::::::::::::::::::::: NP_001 DDNIPRRTTQRIVAPPGGRANITSLG 520 530 >>NP_001304 (OMIM: 602462) dihydropyrimidinase-related p (572 aa) initn: 3063 init1: 3063 opt: 3063 Z-score: 3540.4 bits: 665.0 E(92320): 2e-190 Smith-Waterman score: 3063; 76.2% identity (94.4% similar) in 572 aa overlap (1-572:1-572) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA :::::::.::.:::::::::::.:.:::::.:::.:.::::::::::::::::::::::: NP_001 MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF ..::::::::::.: .: :.::::.::::::::.:::.:::::::::::::::.:::..: NP_001 NGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ ..:.: ::.::::::::::::. :. :..::.:.::.:.::::: ::::.:: .:..: : NP_001 EKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI .::... .. .::. :::::::.::.::.:::..::::::::.::::::.::::: ::: NP_001 LYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::.. :::.:::::::::.:..:: ::::: .:.::::.:::::::.:::::::::::: NP_001 TIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE :::::::::::::::.:.:::.:::::::::.:: ..:::::::::::::::::.:: :: NP_001 FVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI ::.:.:::::.:::::::::::::::::::.:::::::::::::::::.::::::..::: NP_001 RMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK .::.:.:..::::::::::.:::::::::::::.:::...:..: ::.:::: ::. .:. NP_001 TAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS :.: :... :.:: ::.::::: :: .::: .::: :::.::.:.: ::.::::::.:: NP_001 RVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFS 490 500 510 520 530 540 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG ::::::::: :::: .:::::::::.:::::: NP_001 LSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG 550 560 570 >>NP_001378 (OMIM: 601168) dihydropyrimidinase-related p (570 aa) initn: 3067 init1: 2862 opt: 3062 Z-score: 3539.3 bits: 664.8 E(92320): 2.3e-190 Smith-Waterman score: 3062; 76.7% identity (94.7% similar) in 571 aa overlap (1-571:1-569) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA ::::::::::::::::::::::.:::::::::::::::::::::::.::::::::::::: NP_001 MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF ...:::::::::::.:::: .:::..:::::::::::::::::::::::::: .:: :. NP_001 NGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ ..::::::.::::::.:::::..:. ....:.. :.::.:::::.::::.:: .:... . NP_001 EKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI .::... . ..:::::::::::::::.:: :.:..:::::::::::::::.::::: ::: NP_001 LYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::.:::::::.:::::::.:..:.::::::.::.::::::::: ::.:::::::::::: NP_001 TIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE :::::::::::::::..::::. ::::..:::::::.:::::.:::::: :::::::.:: NP_001 FVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI ::::::::::.:::::::::::::::::::.::::::::::.::::.::::::::.:: . NP_001 RMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK :::.:.:. ::::::::: ::.::::: ::::.::::.::::.:.::.:: .:: :.::: NP_001 SAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS ::::: ..:.:..::::.::::: ....::: :::.::. ::.. . :::::::::::: NP_001 RIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPN-PPVRNLHQSGFS 490 500 510 520 530 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG :::.:.:... : ...:::::::::.::::: NP_001 LSGTQVDEGV-RSASKRIVAPPGGRSNITSLS 540 550 560 570 >>NP_006417 (OMIM: 608407) dihydropyrimidinase-related p (572 aa) initn: 3015 init1: 3015 opt: 3015 Z-score: 3484.9 bits: 654.7 E(92320): 2.5e-187 Smith-Waterman score: 3015; 75.7% identity (92.6% similar) in 571 aa overlap (1-571:1-571) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA ::.::::.:::::::::::.::.:::::::::::...:::::::::::::::::.:::.: NP_006 MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGGIKTIDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF :. ::.:::.:::::.::: ::: :::: ::::::::::::::.::: :. :.:::::. NP_006 HGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ .:::: ::: .::::::::::..::..:.::.:::::..:::::::.::.::: : .: : NP_006 EQWRERADSAACCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI .::..:.:::.::.::::::::::. :::.:.:.::::::::::::.::::::::: ::. NP_006 MYEIFSIIRDLGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::.:.:::::.::::::..:..::::...:.::.::::::::::::::::::::::::: NP_006 TIAKQANCPLYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE ::::::..::::: : :. ::: :::::::::::::.:::::::::::.:::::::: :: NP_006 FVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI :::..:.: :..::::::.:::::::::::.::.::::::.:::::::::::.: ..: : NP_006 RMSMVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKII 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK :::::: ..:::::::.::::.: ::::::...:::: . :: :.::..::: ::::::: NP_006 SAKTHNLNVEYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS :::::.::::..::::::::::: :: : : . : . . :.: ..:::::::::::: NP_006 RIKARNRLAEIHGVPRGLYDGPVHEVMVPAKPGSGAPARASCPGKISVPPVRNLHQSGFS 490 500 510 520 530 540 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG :::.: ::.: :::.:.:.::::::.::::: NP_006 LSGSQADDHIARRTAQKIMAPPGGRSNITSLS 550 560 570 >>NP_001275591 (OMIM: 602462) dihydropyrimidinase-relate (566 aa) initn: 2990 init1: 2990 opt: 2990 Z-score: 3456.0 bits: 649.4 E(92320): 9.9e-186 Smith-Waterman score: 2990; 76.0% identity (94.3% similar) in 559 aa overlap (14-572:8-566) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA :::::::::.:.:::::.:::.:.::::::::::::::::::::::: NP_001 MRTTGAHSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF ..::::::::::.: .: :.::::.::::::::.:::.:::::::::::::::.:::..: NP_001 NGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ ..:.: ::.::::::::::::. :. :..::.:.::.:.::::: ::::.:: .:..: : NP_001 EKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI .::... .. .::. :::::::.::.::.:::..::::::::.::::::.::::: ::: NP_001 LYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::.. :::.:::::::::.:..:: ::::: .:.::::.:::::::.:::::::::::: NP_001 TIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE :::::::::::::::.:.:::.:::::::::.:: ..:::::::::::::::::.:: :: NP_001 FVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI ::.:.:::::.:::::::::::::::::::.:::::::::::::::::.::::::..::: NP_001 RMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK .::.:.:..::::::::::.:::::::::::::.:::...:..: ::.:::: ::. .:. NP_001 TAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS :.: :... :.:: ::.::::: :: .::: .::: :::.::.:.: ::.::::::.:: NP_001 RVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFS 480 490 500 510 520 530 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG ::::::::: :::: .:::::::::.:::::: NP_001 LSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG 540 550 560 >>NP_001275590 (OMIM: 602462) dihydropyrimidinase-relate (570 aa) initn: 2990 init1: 2990 opt: 2990 Z-score: 3456.0 bits: 649.4 E(92320): 1e-185 Smith-Waterman score: 2990; 76.0% identity (94.3% similar) in 559 aa overlap (14-572:12-570) 10 20 30 40 50 60 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEA :::::::::.:.:::::.:::.:.::::::::::::::::::::::: NP_001 MQKMNNEVVDKSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEA 10 20 30 40 50 70 80 90 100 110 120 pF1KE1 HSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAF ..::::::::::.: .: :.::::.::::::::.:::.:::::::::::::::.:::..: NP_001 NGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSF 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE1 DQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQ ..:.: ::.::::::::::::. :. :..::.:.::.:.::::: ::::.:: .:..: : NP_001 EKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE1 IYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAI .::... .. .::. :::::::.::.::.:::..::::::::.::::::.::::: ::: NP_001 LYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE1 TIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAA :::.. :::.:::::::::.:..:: ::::: .:.::::.:::::::.:::::::::::: NP_001 TIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAA 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE1 FVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEE :::::::::::::::.:.:::.:::::::::.:: ..:::::::::::::::::.:: :: NP_001 FVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE1 RMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI ::.:.:::::.:::::::::::::::::::.:::::::::::::::::.::::::..::: NP_001 RMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE1 SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYK .::.:.:..::::::::::.:::::::::::::.:::...:..: ::.:::: ::. .:. NP_001 TAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE1 RIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFS :.: :... :.:: ::.::::: :: .::: .::: :::.::.:.: ::.::::::.:: NP_001 RVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFS 480 490 500 510 520 530 550 560 570 pF1KE1 LSGAQIDDNIPRRTTQRIVAPPGGRANITSLG ::::::::: :::: .:::::::::.:::::: NP_001 LSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG 540 550 560 570 >>NP_001014809 (OMIM: 602462) dihydropyrimidinase-relate (686 aa) initn: 2990 init1: 2990 opt: 2990 Z-score: 3454.7 bits: 649.4 E(92320): 1.2e-185 Smith-Waterman score: 2990; 76.0% identity (94.3% similar) in 559 aa overlap (14-572:128-686) 10 20 30 40 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIK :::::::::.:.:::::.:::.:.:::::: NP_001 SPGERDERPPTLRIRRPAPRDLPLGRDNGQSDRLLIKGGRIINDDQSLYADVYLEDGLIK 100 110 120 130 140 150 50 60 70 80 90 100 pF1KE1 QIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTM :::::::::::::::::..::::::::::.: .: :.::::.::::::::.:::.::::: NP_001 QIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTM 160 170 180 190 200 210 110 120 130 140 150 160 pF1KE1 IIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNS ::::::::::.:::..:..:.: ::.::::::::::::. :. :..::.:.::.:.:::: NP_001 IIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNS 220 230 240 250 260 270 170 180 190 200 210 220 pF1KE1 FLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGH : ::::.:: .:..: :.::... .. .::. :::::::.::.::.:::..:::::::: NP_001 FQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGH 280 290 300 310 320 330 230 240 250 260 270 280 pF1KE1 VLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASL .::::::.::::: ::::::.. :::.:::::::::.:..:: ::::: .:.::::.::: NP_001 ALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASL 340 350 360 370 380 390 290 300 310 320 330 340 pF1KE1 GTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAV ::::.:::::::::::::::::::::::::::.:.:::.:::::::::.:: ..:::::: NP_001 GTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAV 400 410 420 430 440 450 350 360 370 380 390 400 pF1KE1 GKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAV :::::::::::.:: ::::.:.:::::.:::::::::::::::::::.:::::::::::: NP_001 GKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAV 460 470 480 490 500 510 410 420 430 440 450 460 pF1KE1 GSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTE :::::.::::::..:::.::.:.:..::::::::::.:::::::::::::.:::...:.. NP_001 GSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNK 520 530 540 550 560 570 470 480 490 500 510 520 pF1KE1 GSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSP : ::.:::: ::. .:.:.: :... :.:: ::.::::: :: .::: .::: :::.:: NP_001 GMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSP 580 590 600 610 620 630 530 540 550 560 570 pF1KE1 AKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG .:.: ::.::::::.::::::::::: :::: .:::::::::.:::::: NP_001 SKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG 640 650 660 670 680 >>NP_001184223 (OMIM: 601168) dihydropyrimidinase-relate (684 aa) initn: 3009 init1: 2776 opt: 2984 Z-score: 3447.8 bits: 648.1 E(92320): 2.9e-185 Smith-Waterman score: 2984; 75.8% identity (94.3% similar) in 562 aa overlap (10-571:124-683) 10 20 30 pF1KE1 MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMED :. :::::::::.:::::::::::::::: NP_001 ESREPAPASPAPAGVEIRSATGKEVLQNLGPKDKSDRLLIKGGRIVNDDQSFYADIYMED 100 110 120 130 140 150 40 50 60 70 80 90 pF1KE1 GLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAG :::::::.:::::::::::::...:::::::::::.:::: .:::..::::::::::::: NP_001 GLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAG 160 170 180 190 200 210 100 110 120 130 140 150 pF1KE1 GTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDH ::::::::::::: .:: :...::::::.::::::.:::::..:. ....:.. :.::. NP_001 GTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDK 220 230 240 250 260 270 160 170 180 190 200 210 pF1KE1 GVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITG :::::.::::.:: .:... ..::... . ..:::::::::::::::.:: :.:..:::: NP_001 GVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITG 280 290 300 310 320 330 220 230 240 250 260 270 pF1KE1 PEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPI :::::::::::.::::: ::::::.:::::::.:::::::.:..:.::::::.::.:::: NP_001 PEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPI 340 350 360 370 380 390 280 290 300 310 320 330 pF1KE1 TASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTA ::::: ::.:::::::::::::::::::::::::::..::::. ::::..:::::::.:: NP_001 TASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTA 400 410 420 430 440 450 340 350 360 370 380 390 pF1KE1 QKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKG :::.:::::: :::::::.::::::::::::.:::::::::::::::::::.:::::::: NP_001 QKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKG 460 470 480 490 500 510 400 410 420 430 440 450 pF1KE1 RIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTL ::.::::.::::::::.:: .:::.:.:. ::::::::: ::.::::: ::::.::::.: NP_001 RISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNL 520 530 540 550 560 570 460 470 480 490 500 510 pF1KE1 HVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSA :::.:.::.:: .:: :.:::::::: ..:.:..::::.::::: ....::: :::.:: NP_001 HVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSA 580 590 600 610 620 630 520 530 540 550 560 570 pF1KE1 KTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG . ::.. . :::::::::::::::.:.:... : ...:::::::::.::::: NP_001 RGSPTRPN-PPVRNLHQSGFSLSGTQVDEGV-RSASKRIVAPPGGRSNITSLS 640 650 660 670 680 572 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:42:05 2019 done: Thu Oct 24 21:42:06 2019 Total Scan time: 4.920 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]