FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2019, 596 aa 1>>>pF1KE2019 596 - 596 aa - 596 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0777+/-0.000893; mu= 21.2962+/- 0.054 mean_var=84.0143+/-16.621, 0's: 0 Z-trim(106.5): 35 B-trim: 38 in 1/51 Lambda= 0.139926 statistics sampled from 9138 (9158) to 9138 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.274), width: 16 Scan time: 1.530 The best scores are: opt bits E(33420) CCDS55262.1 PDP1 gene_id:54704|Hs109|chr8 ( 562) 3818 781.0 0 CCDS6259.1 PDP1 gene_id:54704|Hs109|chr8 ( 537) 3637 744.4 8.5e-215 CCDS10822.1 PDP2 gene_id:57546|Hs109|chr16 ( 529) 1715 356.4 5.3e-98 >>CCDS55262.1 PDP1 gene_id:54704|Hs109|chr8 (562 aa) initn: 3818 init1: 3818 opt: 3818 Z-score: 4167.2 bits: 781.0 E(33420): 0 Smith-Waterman score: 3818; 100.0% identity (100.0% similar) in 562 aa overlap (35-596:1-562) 10 20 30 40 50 60 pF1KE2 ALLSMGRCCCRCCCPRGLWMLSAPCCDDRRMCVCPGPRRIGIPVRSSSLPLFSDAMPAPT :::::::::::::::::::::::::::::: CCDS55 MCVCPGPRRIGIPVRSSSLPLFSDAMPAPT 10 20 30 70 80 90 100 110 120 pF1KE2 QLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QLFFPLIRNCELSRIYGTACYCHHKHLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE2 TQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TQGRRYASTPQKFYLTPPQVNSILKANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIED 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 RRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RRSAATCLQTRGMLLGVFDGHAGCACSQAVSERLFYYIAVSLLPHETLLEIENAVESGRA 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE2 LLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDVKEALINAFKRLDN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KE2 DISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DISLEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSW 280 290 300 310 320 330 370 380 390 400 410 420 pF1KE2 SAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQ 340 350 360 370 380 390 430 440 450 460 470 480 pF1KE2 KRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMH 400 410 420 430 440 450 490 500 510 520 530 540 pF1KE2 RQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RQDVVRIVGEYLTGMHHQQPIAVGGYKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRH 460 470 480 490 500 510 550 560 570 580 590 pF1KE2 AVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AVGNNEFGTVDHERLSKMLSLPEELARMYRDDITIIVVQFNSHVVGAYQNQE 520 530 540 550 560 >>CCDS6259.1 PDP1 gene_id:54704|Hs109|chr8 (537 aa) initn: 3637 init1: 3637 opt: 3637 Z-score: 3970.0 bits: 744.4 E(33420): 8.5e-215 Smith-Waterman score: 3637; 100.0% identity (100.0% similar) in 537 aa overlap (60-596:1-537) 30 40 50 60 70 80 pF1KE2 CDDRRMCVCPGPRRIGIPVRSSSLPLFSDAMPAPTQLFFPLIRNCELSRIYGTACYCHHK :::::::::::::::::::::::::::::: CCDS62 MPAPTQLFFPLIRNCELSRIYGTACYCHHK 10 20 30 90 100 110 120 130 140 pF1KE2 HLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 HLCCSSSYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQKFYLTPPQVNSILK 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE2 ANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ANEYSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE2 CSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 CSQAVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFN 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE2 SLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SLRTYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFS 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE2 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHP 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE2 KSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 KSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYH 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE2 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 TPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVRIVGEYLTGMHHQQPIAVGG 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE2 YKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 YKVTLGQMHGLLTERRTKMSSVFEDQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEEL 460 470 480 490 500 510 570 580 590 pF1KE2 ARMYRDDITIIVVQFNSHVVGAYQNQE ::::::::::::::::::::::::::: CCDS62 ARMYRDDITIIVVQFNSHVVGAYQNQE 520 530 >>CCDS10822.1 PDP2 gene_id:57546|Hs109|chr16 (529 aa) initn: 1357 init1: 586 opt: 1715 Z-score: 1873.2 bits: 356.4 E(33420): 5.3e-98 Smith-Waterman score: 1715; 54.4% identity (79.9% similar) in 472 aa overlap (126-592:61-525) 100 110 120 130 140 150 pF1KE2 SYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQ---KFYLTPPQVNSILKANE .. :..:: . .. :.: :.: .:.:.: CCDS10 VSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE2 YSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQ . :. ..... .:.: :.:::: ::.:.::::..:.:::: :...:.::::.: ::.: CCDS10 TTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQ 100 110 120 130 140 150 220 230 240 250 260 270 pF1KE2 AVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLR :::::::::.::::. :.:: ..:.:.:: . :::::.: :::.: . :........ :: CCDS10 AVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLR 160 170 180 190 200 210 280 290 300 310 320 330 pF1KE2 TYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGAT .:::::.::. ....:::. .:.:::.::::: :. . : :.::::::: CCDS10 VYWQELLDLHM--EMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGAT 220 230 240 250 260 340 350 360 370 380 390 pF1KE2 ACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSE ::.:::::. :::::.:: ::.:::::..: :: . :. :::: :. :: ::: :::.:: CCDS10 ACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESE 270 280 290 300 310 320 400 410 420 430 440 450 pF1KE2 AKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPP .... .:::::.:.: ::::::..::: .::. ..: : . : : .: ::.:.::: CCDS10 DRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIY-QFTPPHYYTPP 330 340 350 360 370 380 460 470 480 490 500 510 pF1KE2 YLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVR-IVGEYLTGMHHQQPIAVGGYK :::::::::::::::::::::::.::::. . .:::: .::. . :. .: CCDS10 YLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLA--QRP 390 400 410 420 430 440 520 530 540 550 560 570 pF1KE2 VTLGQMHGLLTERRTKMSSVFE-DQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELA ..:: :..:: .: : :.. : ::::::.:::::.::::.: .. :::. ::.:::.:: CCDS10 ANLGLMQSLLLQR--KASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLA 450 460 470 480 490 500 580 590 pF1KE2 RMYRDDITIIVVQFNSHVVGAYQNQE ::::::::. :: :::. .::: CCDS10 RMYRDDITVTVVYFNSESIGAYYKGG 510 520 596 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 15:42:43 2019 done: Tue Jul 16 15:42:44 2019 Total Scan time: 1.530 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]